Nicotinamide N-methyltransferase inhibits autophagy induced by oxidative stress through suppressing the AMPK pathway in breast cancer cells

Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts

(2019) Mark A. Eckert et al.   NATURE

A molecular perspective of mammalian autophagosome biogenesis

(2018) Thomas J. Mercer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nicotinamide-N-methyltransferase controls behavior, neurodegeneration and lifespan by regulating neuronal autophagy

(2018) Kathrin Schmeisser et al.   PLoS Genetics

NNMT depletion contributes to liver cancer cell survival by enhancing autophagy under nutrient starvation

(2018) Ji Hye Shin et al.   Oncogenesis

Halofuginone dually regulates autophagic flux through nutrient-sensing pathways in colorectal cancer

(2017) Guo-Qing Chen et al.   Cell Death & Disease

Nicotinamide N-methyltransferase enhances resistance to 5-fluorouracil in colorectal cancer cells through inhibition of the ASK1-p38 MAPK pathway

(2016) Xinyou Xie et al.   Oncotarget

Cross-cancer profiling of molecular alterations within the human autophagy interaction network

(2015) Chandra B Lebovitz et al.   Autophagy

Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization

(2015) Shangyu Hong et al.   NATURE MEDICINE

MnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signalling in cancer

(2015) Peter C. Hart et al.   Nature Communications

Oxidative stress induces autophagy in response to multiple noxious stimuli in retinal ganglion cells

(2014) Wen-jian Lin et al.   Autophagy

Metabolic Control of Autophagy

(2014) Lorenzo Galluzzi et al.   CELL

To Be or Not to Be? How Selective Autophagy and Cell Death Govern Cell Fate

(2014) Douglas R. Green et al.   CELL

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity

(2014) Daniel Kraus et al.   NATURE

Down-Regulation of Nicotinamide N-methyltransferase Induces Apoptosis in Human Breast Cancer Cells via the Mitochondria-Mediated Pathway

(2014) Jun Zhang et al.   PLoS One

ROS play a critical role in the differentiation of alternatively activated macrophages and the occurrence of tumor-associated macrophages

(2013) Yan Zhang et al.   CELL RESEARCH

Atg9 Interacts with dTRAF2/TRAF6 to Regulate Oxidative Stress-Induced JNK Activation and Autophagy Induction

(2013) Hong-Wen Tang et al.   DEVELOPMENTAL CELL

Mechanism of Siglec-8–mediated cell death in IL-5–activated eosinophils: Role for reactive oxygen species–enhanced MEK/ERK activation

(2013) Gen Kano et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink

(2013) Olesya A Ulanovskaya et al.   Nature Chemical Biology

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

Reactive Oxygen Species-Induced Autophagic Degradation of Helicobacter pylori CagA Is Specifically Suppressed in Cancer Stem-like Cells

(2012) Hitoshi Tsugawa et al.   Cell Host & Microbe

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

A Genome-Wide siRNA Screen Reveals Multiple mTORC1 Independent Signaling Pathways Regulating Autophagy under Normal Nutritional Conditions

(2010) Marta M. Lipinski et al.   DEVELOPMENTAL CELL

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

(2010) Brinda Ravikumar et al.   PHYSIOLOGICAL REVIEWS

Expression of nicotinamide N-methyltransferase in hepatocellular carcinoma is associated with poor prognosis

(2009) Jongmin Kim et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Regulation of autophagy by cytoplasmic p53

(2008) Ezgi Tasdemir et al.   NATURE CELL BIOLOGY