Cyclin-dependent kinases

Phylogenetic analysis of CDK and cyclin proteins in premetazoan lineages

(2014) Lihuan Cao et al.   BMC EVOLUTIONARY BIOLOGY

In a Nongenomic Action, Steroid Hormone 20-Hydroxyecdysone Induces Phosphorylation of Cyclin-Dependent Kinase 10 to Promote Gene Transcription

(2014) Wen Liu et al.   ENDOCRINOLOGY

Cyclin-Dependent Kinase 6 Is a Chromatin-Bound Cofactor for NF-κB-Dependent Gene Expression

(2014) Katja Handschick et al.   MOLECULAR CELL

A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis

(2013) Karoline Kollmann et al.   CANCER CELL

Genome-wide Profiling of Genetic Synthetic Lethality Identifies CDK12 as a Novel Determinant of PARP1/2 Inhibitor Sensitivity

(2013) I. Bajrami et al.   CANCER RESEARCH

Cdks, cyclins and CKIs: roles beyond cell cycle regulation

(2013) S. Lim et al.   DEVELOPMENT

CCRK depletion inhibits glioblastoma cell proliferation in a cilium-dependent manner

(2013) Ying Yang et al.   EMBO REPORTS

CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome

(2013) V. J. Guen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The multitalented Mediator complex

(2013) Jonas O.P. Carlsten et al.   TRENDS IN BIOCHEMICAL SCIENCES

Cell cycle control across the eukaryotic kingdom

(2013) Hirofumi Harashima et al.   TRENDS IN CELL BIOLOGY

Extraneuronal activities and regulatory mechanisms of the atypical cyclin-dependent kinase Cdk5

(2012) Abul Arif   BIOCHEMICAL PHARMACOLOGY

Orphan kinases turn eccentric

(2012) Petra Mikolcevic et al.   CELL CYCLE

Phylogenetic analysis reveals the evolution and diversification of cyclins in eukaryotes

(2012) Zhaowu Ma et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION

Exome sequencing of hepatitis B virus–associated hepatocellular carcinoma

(2012) Jian Huang et al.   NATURE GENETICS

Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II

(2012) Stéphane Larochelle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Deciphering the retinoblastoma protein phosphorylation code

(2012) Seth M. Rubin   TRENDS IN BIOCHEMICAL SCIENCES

Updating the RNA polymerase CTD code: adding gene-specific layers

(2012) Sylvain Egloff et al.   TRENDS IN GENETICS

Cyclin K goes with Cdk12 and Cdk13

(2012) Jiri Kohoutek et al.   Cell Division

Cdk11-CyclinL Controls the Assembly of the RNA Polymerase II Mediator Complex

(2012) Julie Drogat et al.   Cell Reports

The cyclin-dependent kinase PITSLRE/CDK11 is required for successful autophagy

(2011) Simon Wilkinson et al.   Autophagy

A history of TFIIH: Two decades of molecular biology on a pivotal transcription/repair factor

(2011) Jean-Marc Egly et al.   DNA REPAIR

The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes

(2011) D. Blazek et al.   GENES & DEVELOPMENT

Cell cycle–related kinase is a direct androgen receptor–regulated gene that drives β-catenin/T cell factor–dependent hepatocarcinogenesis

(2011) Hai Feng et al.   JOURNAL OF CLINICAL INVESTIGATION

Cyclin-Dependent Kinase 16/PCTAIRE Kinase 1 Is Activated by Cyclin Y and Is Essential for Spermatogenesis

(2011) P. Mikolcevic et al.   MOLECULAR AND CELLULAR BIOLOGY

Cdc14 phosphatase promotes segregation of telomeres through repression of RNA polymerase II transcription

(2011) Andres Clemente-Blanco et al.   NATURE CELL BIOLOGY

A novel interplay between oncogenic PFTK1 protein kinase and tumor suppressor TAGLN2 in the control of liver cancer cell motility

(2011) W K C Leung et al.   ONCOGENE

Cdk5: a multifaceted kinase in neurodegenerative diseases

(2011) Zelda H. Cheung et al.   TRENDS IN CELL BIOLOGY

CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1

(2010) B. Bartkowiak et al.   GENES & DEVELOPMENT

Emerging links between CDK cell cycle regulators and Wnt signaling

(2010) Gary Davidson et al.   TRENDS IN CELL BIOLOGY

CDK11p58 represses vitamin D receptor-mediated transcriptional activation through promoting its ubiquitin–proteasome degradation

(2009) Yayun Chi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cell Cycle Control of Wnt Receptor Activation

(2009) Gary Davidson et al.   DEVELOPMENTAL CELL

Repression of Estrogen Receptor alpha by CDK11p58 Through Promoting its Ubiquitin-Proteasome Degradation

(2009) Y. Wang et al.   JOURNAL OF BIOCHEMISTRY

Cyclin-dependent kinases: a family portrait

(2009) Marcos Malumbres et al.   NATURE CELL BIOLOGY

The structure of CDK4/cyclin D3 has implications for models of CDK activation

(2009) T. Takaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of human CDK4 in complex with a D-type cyclin

(2009) P. J. Day et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of CDK10 as an Important Determinant of Resistance to Endocrine Therapy for Breast Cancer

(2008) Elizabeth Iorns et al.   CANCER CELL

The multi-tasking P-TEFb complex

(2008) Vanessa Brès et al.   CURRENT OPINION IN CELL BIOLOGY

Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate

(2008) Hideki Yokoyama et al.   JOURNAL OF CELL BIOLOGY

E2F1 represses β-catenin transcription and is antagonized by both pRB and CDK8

(2008) Erick J. Morris et al.   NATURE

CDK8 is a colorectal cancer oncogene that regulates β-catenin activity

(2008) Ron Firestein et al.   NATURE