From Mesenchymal Stromal Cells to Engineered Extracellular Vesicles: A New Therapeutic Paradigm
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Title
From Mesenchymal Stromal Cells to Engineered Extracellular Vesicles: A New Therapeutic Paradigm
Authors
Keywords
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Journal
Frontiers in Cell and Developmental Biology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-07-20
DOI
10.3389/fcell.2021.705676
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Note: Only part of the references are listed.- A Versatile Platform for Generating Engineered Extracellular Vesicles with Defined Therapeutic Properties
- (2021) Kevin Dooley et al. MOLECULAR THERAPY
- Mesenchymal Stem Cell–Derived Exosomes: A Promising Biological Tool in Nanomedicine
- (2021) Wumei Wei et al. Frontiers in Pharmacology
- Exosomal delivery of NF-κB inhibitor delays LPS-induced preterm birth and modulates fetal immune cell profile in mouse models
- (2021) Samantha Sheller-Miller et al. Science Advances
- Natural or Synthetic RNA Delivery: A Stoichiometric Comparison of Extracellular Vesicles and Synthetic Nanoparticles
- (2021) Daniel E. Murphy et al. NANO LETTERS
- Critical considerations for the development of potency tests for therapeutic applications of mesenchymal stromal cell-derived small extracellular vesicles
- (2021) Mario Gimona et al. CYTOTHERAPY
- Therapeutic Efficacy of Cryopreserved, Allogeneic Extracellular Vesicles for Treatment of Acute Myocardial Infarction
- (2021) Jennifer J. Chung et al. International Heart Journal
- Encapsulation of Hydrophilic Compounds in Small Extracellular Vesicles: Loading Capacity and Impact on Vesicle Functions
- (2021) Britta Franziska Hettich et al. Advanced Healthcare Materials
- Assessment of Tumorigenic Potential in Mesenchymal-Stem/Stromal-Cell-Derived Small Extracellular Vesicles (MSC-sEV)
- (2021) Thong Teck Tan et al. Pharmaceuticals
- Mesenchymal stem cell-derived exosomal miR-223 regulates neuronal cell apoptosis
- (2020) Hong Wei et al. Cell Death & Disease
- Boosting the Biogenesis and Secretion of Mesenchymal Stem Cell-Derived Exosomes
- (2020) Jinli Wang et al. Cells
- Mesenchymal Stem Cell-Derived Extracellular Vesicles: Challenges in Clinical Applications
- (2020) Austin Gowen et al. Frontiers in Cell and Developmental Biology
- Functionally engineered extracellular vesicles improve bone regeneration
- (2020) Chun-Chieh Huang et al. Acta Biomaterialia
- Intranasal delivery of mesenchymal stem cell‐derived extracellular vesicles exerts immunomodulatory and neuroprotective effects in a 3xTg model of Alzheimer's disease
- (2020) Morris Losurdo et al. Stem Cells Translational Medicine
- Sex-Specific Transcriptome Differences in Human Adipose Mesenchymal Stem Cells
- (2020) Eva Bianconi et al. Genes
- Shattering barriers toward clinically meaningful MSC therapies
- (2020) Oren Levy et al. Science Advances
- Production, safety and efficacy of iPSC-derived mesenchymal stromal cells in acute steroid-resistant graft versus host disease: a phase I, multicenter, open-label, dose-escalation study
- (2020) Adrian J. C. Bloor et al. NATURE MEDICINE
- Extracellular Vesicles as an Efficient and Versatile System for Drug Delivery
- (2020) Xuan T. T. Dang et al. Cells
- Engineered extracellular vesicle decoy receptor-mediated modulation of the IL6 trans-signalling pathway in muscle
- (2020) Mariana Conceição et al. BIOMATERIALS
- Exosome surface display of IL-12 results in tumor-retained pharmacology with superior potency and limited systemic exposure compared to recombinant IL-12
- (2020) Nuruddeen D. Lewis et al. MOLECULAR CANCER THERAPEUTICS
- Cymerus™ iPSC-MSCs significantly prolong survival in a pre-clinical, humanized mouse model of Graft-vs-host disease
- (2019) E. Ilker Ozay et al. Stem Cell Research
- The current state and future directions of RNAi-based therapeutics
- (2019) Ryan L. Setten et al. NATURE REVIEWS DRUG DISCOVERY
- Manufacturing and characterization of extracellular vesicles from umbilical cord–derived mesenchymal stromal cells for clinical testing
- (2019) Eva Rohde et al. CYTOTHERAPY
- Concise Review: Challenges in Clinical Development of Mesenchymal Stromal/Stem Cells
- (2019) Ilenia Mastrolia et al. Stem Cells Translational Medicine
- Exosomes produced from 3D cultures of umbilical cord mesenchymal stem cells in a hollow-fiber bioreactor show improved osteochondral regeneration activity
- (2019) Litao Yan et al. CELL BIOLOGY AND TOXICOLOGY
- Methotrexate-Loaded Extracellular Vesicles Functionalized with Therapeutic and Targeted Peptides for the Treatment of Glioblastoma Multiforme
- (2018) Zhilan Ye et al. ACS Applied Materials & Interfaces
- Technologies for large-scale umbilical cord-derived MSC expansion: Experimental performance and cost of goods analysis
- (2018) Amanda Mizukami et al. BIOCHEMICAL ENGINEERING JOURNAL
- Impact of allogeneic stem cell manufacturing decisions on cost of goods, process robustness and reimbursement
- (2018) Tania D. Pereira Chilima et al. BIOCHEMICAL ENGINEERING JOURNAL
- Mesenchymal Stromal Cell Characteristics and Regenerative Potential in Cardiovascular Disease
- (2018) F. C. C. van Rhijn-Brouwer et al. CELL TRANSPLANTATION
- Ethical and Safety Issues of Stem Cell-Based Therapy
- (2018) Vladislav Volarevic et al. International Journal of Medical Sciences
- Employing mesenchymal stem cells to support tumor-targeted delivery of extracellular vesicle (EV)-encapsulated microRNA-379
- (2018) K. P. O’Brien et al. ONCOGENE
- Manufacturing Exosomes: A Promising Therapeutic Platform
- (2018) Ivano Luigi Colao et al. TRENDS IN MOLECULAR MEDICINE
- Induced pluripotent stem cell-derived mesenchymal stem cells activate quiescent T cells and elevate regulatory T cell response via NF-κB in allergic rhinitis patients
- (2018) Xing-Liang Fan et al. Stem Cell Research & Therapy
- Isolation of Extracellular Vesicles: General Methodologies and Latest Trends
- (2018) Maria Yu. Konoshenko et al. Biomed Research International
- Multiparametric Analysis of Circulating Exosomes and Other Small Extracellular Vesicles by Advanced Imaging Flow Cytometry
- (2018) Sotiris Mastoridis et al. Frontiers in Immunology
- Exosomes produced from three-dimensional cultures of mesenchymal stem cells by tangential flow filtration show higher yield and improved activity
- (2018) Reka Agnes Haraszti et al. MOLECULAR THERAPY
- Extracellular vesicles protect glucuronidase model enzymes during freeze-drying
- (2018) Julia Frank et al. Scientific Reports
- Concise Review: Mesenchymal Stem Cells Derived from Human Pluripotent Cells, an Unlimited and Quality-Controllable Source, for Therapeutic Applications
- (2018) Bin Jiang et al. STEM CELLS
- Application of Mesenchymal Stem Cell-Derived Extracellular Vesicles for Stroke: Biodistribution and MicroRNA Study
- (2018) Gyeong Joon Moon et al. Translational Stroke Research
- To Protect and to Preserve: Novel Preservation Strategies for Extracellular Vesicles
- (2018) Gina D. Kusuma et al. Frontiers in Pharmacology
- Tangential Flow Filtration for Highly Efficient Concentration of Extracellular Vesicles from Large Volumes of Fluid
- (2018) Sara Busatto et al. Cells
- Cell type-specific and common characteristics of exosomes derived from mouse cell lines: Yield, physicochemical properties, and pharmacokinetics
- (2017) Chonlada Charoenviriyakul et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Manufacturing of Human Extracellular Vesicle-Based Therapeutics for Clinical Use
- (2017) Mario Gimona et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Pseudotyping exosomes for enhanced protein delivery in mammalian cells
- (2017) Conary Meyer et al. International Journal of Nanomedicine
- Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
- (2017) Sushrut Kamerkar et al. NATURE
- CRISPR/Cas9-mediated reversibly immortalized mouse bone marrow stromal stem cells (BMSCs) retain multipotent features of mesenchymal stem cells (MSCs)
- (2017) Xue Hu et al. Oncotarget
- Exosomes derived from platelet-rich plasma promote the re-epithelization of chronic cutaneous wounds via activation of YAP in a diabetic rat model
- (2017) Shang-Chun Guo et al. Theranostics
- Myocardial reparative functions of exosomes from mesenchymal stem cells are enhanced by hypoxia treatment of the cells via transferring microRNA-210 in an nSMase2-dependent way
- (2017) Jinyun Zhu et al. Artificial Cells Nanomedicine and Biotechnology
- Mesenchymal Stem Cells Deliver Exogenous MicroRNA-let7c via Exosomes to Attenuate Renal Fibrosis
- (2016) Bo Wang et al. MOLECULAR THERAPY
- Fetal Bovine Serum RNA Interferes with the Cell Culture derived Extracellular RNA
- (2016) Zhiyun Wei et al. Scientific Reports
- Recent Developments in Cellular Immunotherapy for HSCT-Associated Complications
- (2016) Monica Reis et al. Frontiers in Immunology
- Identification and Characterization of 293T Cell-Derived Exosomes by Profiling the Protein, mRNA and MicroRNA Components
- (2016) Jing Li et al. PLoS One
- The Effect of Gender on Mesenchymal Stem Cell (MSC) Efficacy in Neonatal Hyperoxia-Induced Lung Injury
- (2016) Ibrahim Sammour et al. PLoS One
- Trehalose prevents aggregation of exosomes and cryodamage
- (2016) Steffi Bosch et al. Scientific Reports
- MSC Transplantation Improves Osteopenia via Epigenetic Regulation of Notch Signaling in Lupus
- (2015) Shiyu Liu et al. Cell Metabolism
- Stem Cell Therapies in Clinical Trials: Progress and Challenges
- (2015) Alan Trounson et al. Cell Stem Cell
- Intracarotid Infusion of Mesenchymal Stem Cells in an Animal Model of Parkinson's Disease, Focusing on Cell Distribution and Neuroprotective and Behavioral Effects
- (2015) Silvia Cerri et al. Stem Cells Translational Medicine
- Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: A new approach for drug delivery
- (2014) Luisa Pascucci et al. JOURNAL OF CONTROLLED RELEASE
- MSC-derived exosomes: a novel tool to treat therapy-refractory graft-versus-host disease
- (2014) L Kordelas et al. LEUKEMIA
- MSCs derived from iPSCs with a modified protocol are tumor-tropic but have much less potential to promote tumors than bone marrow MSCs
- (2014) Qingguo Zhao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Treatment of Graft versus Host Disease with Mesenchymal Stromal Cells: A Phase I Study on 40 Adult and Pediatric Patients
- (2013) Martino Introna et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Serum-free media for the production of human mesenchymal stromal cells: a review
- (2013) S. Gottipamula et al. CELL PROLIFERATION
- Genetically Matched Human iPS Cells Reveal that Propensity for Cartilage and Bone Differentiation Differs with Clones, not Cell Type of Origin
- (2013) Akira Nasu et al. PLoS One
- The Relative Contribution of Paracine Effect versus Direct Differentiation on Adipose-Derived Stem Cell Transplantation Mediated Cardiac Repair
- (2013) Dezhong Yang et al. PLoS One
- Exosome-Mediated Transfer of miR-133b from Multipotent Mesenchymal Stromal Cells to Neural Cells Contributes to Neurite Outgrowth
- (2012) Hongqi Xin et al. STEM CELLS
- Ex VivoExpansion of Human Mesenchymal Stem Cells in Defined Serum-Free Media
- (2012) Sunghoon Jung et al. Stem Cells International
- Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC
- (2011) Ralf Hass et al. Cell Communication and Signaling
- The MSC: An Injury Drugstore
- (2011) Arnold I. Caplan et al. Cell Stem Cell
- Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
- (2011) Lydia Alvarez-Erviti et al. NATURE BIOTECHNOLOGY
- Intravenous administration of mesenchymal stem cells exerts therapeutic effects on parkinsonian model of rats: Focusing on neuroprotective effects of stromal cell-derived factor-1α
- (2010) Feifei Wang et al. BMC NEUROSCIENCE
- Paracrine Factors of Multipotent Stromal Cells Ameliorate Lung Injury in an Elastase-induced Emphysema Model
- (2010) Ahmed M Katsha et al. MOLECULAR THERAPY
- Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury
- (2010) Ruenn Chai Lai et al. Stem Cell Research
- Mesenchymal Stem Cell-Derived Microvesicles Protect Against Acute Tubular Injury
- (2009) S. Bruno et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Aging and Replicative Senescence Have Related Effects on Human Stem and Progenitor Cells
- (2009) Wolfgang Wagner et al. PLoS One
- Age-related intrinsic changes in human bone-marrow-derived mesenchymal stem cells and their differentiation to osteoblasts
- (2008) Shuanhu Zhou et al. AGING CELL
- Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium
- (2008) Leo Timmers et al. Stem Cell Research
- Age-related changes in human bone marrow-derived mesenchymal stem cells: Consequences for cell therapies
- (2007) A. Stolzing et al. MECHANISMS OF AGEING AND DEVELOPMENT
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