Production, safety and efficacy of iPSC-derived mesenchymal stromal cells in acute steroid-resistant graft versus host disease: a phase I, multicenter, open-label, dose-escalation study
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Title
Production, safety and efficacy of iPSC-derived mesenchymal stromal cells in acute steroid-resistant graft versus host disease: a phase I, multicenter, open-label, dose-escalation study
Authors
Keywords
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Journal
NATURE MEDICINE
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-09-15
DOI
10.1038/s41591-020-1050-x
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Note: Only part of the references are listed.- Combined Mesenchymal Stromal Cell Therapy and ECMO in ARDS: A Controlled Experimental Study in Sheep
- (2020) Jonathan E Millar et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
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- (2019) E. Ilker Ozay et al. Stem Cell Research
- Challenges for mesenchymal stromal cell therapies
- (2019) Ivan Martin et al. Science Translational Medicine
- iPSC- and mesenchymoangioblast-derived mesenchymal stem cells provide greater protection against experimental chronic allergic airways disease compared with a clinically used corticosteroid
- (2019) Simon G. Royce et al. FASEB JOURNAL
- A Phase 3 Randomized Study of Remestemcel-L versus Placebo Added to Second-Line Therapy in Patients with Steroid-Refractory Acute Graft-versus-Host Disease
- (2019) Partow Kebriaei et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
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- (2019) Mohammad Afzal Khan et al. Stem Cell Research & Therapy
- Trends in mesenchymal stem cell clinical trials 2004‐2018: Is efficacy optimal in a narrow dose range?
- (2019) Maciej Kabat et al. Stem Cells Translational Medicine
- Mesenchymal Stem Cell-Derived Exosomes and Other Extracellular Vesicles as New Remedies in the Therapy of Inflammatory Diseases
- (2019) Carl Randall Harrell et al. Cells
- Effective treatment of steroid and therapy-refractory acute graft-versus-host disease with a novel mesenchymal stromal cell product (MSC-FFM)
- (2018) Peter Bader et al. BONE MARROW TRANSPLANTATION
- Mesenchymal Stromal Cells: Clinical Challenges and Therapeutic Opportunities
- (2018) Jacques Galipeau et al. Cell Stem Cell
- The mesenchymoangioblast, mesodermal precursor for mesenchymal and endothelial cells
- (2018) Igor I. Slukvin et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- iPSC-Derived Cardiomyocytes Taken to Rescue Infarcted Heart Muscle in Coronary Heart Disease Patients
- (2018) Seppo Ylä-Herttuala MOLECULAR THERAPY
- Intranasal administration of mesenchymoangioblast-derived mesenchymal stem cells abrogates airway fibrosis and airway hyperresponsiveness associated with chronic allergic airways disease
- (2017) Simon G. Royce et al. FASEB JOURNAL
- Autologous Induced Stem-Cell–Derived Retinal Cells for Macular Degeneration
- (2017) NEW ENGLAND JOURNAL OF MEDICINE
- Etanercept for steroid-refractory acute graft-versus-host disease: A single center experience
- (2017) Cornelis N. De Jong et al. PLoS One
- Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation
- (2017) Antonio Galleu et al. Science Translational Medicine
- Mesenchymoangioblast-derived mesenchymal stromal cells inhibit cell damage, tissue damage and improve peripheral blood flow following hindlimb ischemic injury in mice
- (2016) Jill M. Koch et al. CYTOTHERAPY
- A robust potency assay highlights significant donor variation of human mesenchymal stem/progenitor cell immune modulatory capacity and extended radio-resistance
- (2015) Nina Ketterl et al. Stem Cell Research & Therapy
- Etanercept for steroid-refractory acute graft versus host disease following allogeneic hematopoietic stem cell transplantation
- (2014) Joo Han Park et al. KOREAN JOURNAL OF INTERNAL MEDICINE
- Tenascin C Promotes Hematoendothelial Development and T Lymphoid Commitment from Human Pluripotent Stem Cells in Chemically Defined Conditions
- (2014) Gene Uenishi et al. Stem Cell Reports
- Phenotype, donor age and gender affect function of human bone marrow-derived mesenchymal stromal cells
- (2013) Georg Siegel et al. BMC Medicine
- The mesenchymal stromal cells dilemma—does a negative phase III trial of random donor mesenchymal stromal cells in steroid-resistant graft-versus-host disease represent a death knell or a bump in the road?
- (2013) Jacques Galipeau CYTOTHERAPY
- Mesenchymal Stromal Cell Characteristics Vary Depending on Their Origin
- (2013) Heike Wegmeyer et al. STEM CELLS AND DEVELOPMENT
- Mesenchymal stem or stromal cells: a review of clinical applications and manufacturing practices
- (2013) Ratti Ram Sharma et al. TRANSFUSION
- Long-Term Complications, Immunologic Effects, and Role of Passage for Outcome in Mesenchymal Stromal Cell Therapy
- (2011) Lena von Bahr et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Human MSC Suppression Correlates With Cytokine Induction of Indoleamine 2,3-Dioxygenase and Bystander M2 Macrophage Differentiation
- (2011) Moïra François et al. MOLECULAR THERAPY
- Chemically defined conditions for human iPSC derivation and culture
- (2011) Guokai Chen et al. NATURE METHODS
- Generation of Induced Pluripotent Stem Cells from CD34+ Cells across Blood Drawn from Multiple Donors with Non-Integrating Episomal Vectors
- (2011) Amanda A. Mack et al. PLoS One
- A Mesoderm-Derived Precursor for Mesenchymal Stem and Endothelial Cells
- (2010) Maxim A. Vodyanik et al. Cell Stem Cell
- Replicative Senescence of Mesenchymal Stem Cells: A Continuous and Organized Process
- (2008) Wolfgang Wagner et al. PLoS One
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