- Home
- Publications
- Publication Search
- Publication Details
Title
The Hematopoietic Bone Marrow Niche Ecosystem
Authors
Keywords
-
Journal
Frontiers in Cell and Developmental Biology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-07-23
DOI
10.3389/fcell.2021.705410
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Loss of KDM4B exacerbates bone-fat imbalance and mesenchymal stromal cell exhaustion in skeletal aging
- (2021) Peng Deng et al. Cell Stem Cell
- A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis
- (2021) Bo Shen et al. NATURE
- In situ mapping identifies distinct vascular niches for myelopoiesis
- (2021) Jizhou Zhang et al. NATURE
- Connecting the Dots: Resolving the Bone Marrow Niche Heterogeneity
- (2021) Igor Dolgalev et al. Frontiers in Cell and Developmental Biology
- Radiation-induced bystander effects impair transplanted human hematopoietic stem cells via oxidative DNA damage
- (2021) Tao Cheng et al. BLOOD
- Bone marrow stromal cells from MDS and AML patients show increased adipogenic potential with reduced Delta-like-1 expression
- (2021) Marie-Theresa Weickert et al. Scientific Reports
- The effect of exercise and nutrition interventions on physical functioning in patients undergoing haematopoietic stem cell transplantation: a systematic review and meta-analysis
- (2021) Marianne C. Prins et al. SUPPORTIVE CARE IN CANCER
- Conditioned Medium from Human Tonsil-Derived Mesenchymal Stem Cells Enhances Bone Marrow Engraftment via Endothelial Cell Restoration by Pleiotrophin
- (2020) Yu-Hee Kim et al. Cells
- Mesenchymal niche remodeling impairs hematopoiesis via stanniocalcin 1 in acute myeloid leukemia
- (2020) Alexander Waclawiczek et al. JOURNAL OF CLINICAL INVESTIGATION
- Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment
- (2020) Leilei Zhong et al. eLife
- Inferring Gene Networks in Bone Marrow Hematopoietic Stem Cell-Supporting Stromal Niche Populations
- (2020) Christophe Desterke et al. iScience
- Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis
- (2020) Nils B. Leimkühler et al. Cell Stem Cell
- AMD3100 redosing fails to repeatedly mobilize hematopoietic stem cells in the nonhuman primate and humanized mouse
- (2020) Clare Samuelson et al. EXPERIMENTAL HEMATOLOGY
- Manipulating niche composition limits damage to haematopoietic stem cells during Plasmodium infection
- (2020) Myriam L. R. Haltalli et al. NATURE CELL BIOLOGY
- UniProt: the universal protein knowledgebase in 2021
- (2020) et al. NUCLEIC ACIDS RESEARCH
- Restricted Hematopoietic Progenitors and Erythropoiesis Require SCF from Leptin Receptor+ Niche Cells in the Bone Marrow
- (2019) Stefano Comazzetto et al. Cell Stem Cell
- Integrin alpha11 is an Osteolectin receptor and is required for the maintenance of adult skeletal bone mass
- (2019) Bo Shen et al. eLife
- S100A9-induced overexpression of PD-1/PD-L1 contributes to ineffective hematopoiesis in myelodysplastic syndromes
- (2019) Pinyang Cheng et al. LEUKEMIA
- P62 deficiency shifts mesenchymal/stromal stem cell commitment toward adipogenesis and disrupts bone marrow homeostasis in aged mice
- (2019) Giovanna Lacava et al. JOURNAL OF CELLULAR PHYSIOLOGY
- An early-senescence state in aged mesenchymal stromal cells contributes to hematopoietic stem and progenitor cell clonogenic impairment through the activation of a pro-inflammatory program
- (2019) Daniela Gnani et al. AGING CELL
- A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia
- (2019) Ninib Baryawno et al. CELL
- The vascular bone marrow niche influences outcome in chronic myeloid leukemia via the E-selectin - SCL/TAL1 - CD44 axis
- (2019) Parimala Sonika Godavarthy et al. HAEMATOLOGICA
- Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation
- (2019) Adam C. Wilkinson et al. NATURE
- The bone marrow microenvironment at single-cell resolution
- (2019) Anastasia N. Tikhonova et al. NATURE
- Prospective isolation of non-hematopoietic cells of the niche and their differential molecular interactions with HSCs
- (2019) Nicole Mende et al. BLOOD
- TNF-alpha driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging
- (2019) Pavel Davizon-Castillo et al. BLOOD
- Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging
- (2019) Ya-Hsuan Ho et al. Cell Stem Cell
- Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping
- (2019) Nicolas Severe et al. Cell Stem Cell
- Multilevel defects in the hematopoietic niche in essential thrombocythemia
- (2019) Ting Sun et al. HAEMATOLOGICA
- Plasma Cells Are Obligate Effectors of Enhanced Myelopoiesis in Aging Bone Marrow
- (2019) Peter D. Pioli et al. IMMUNITY
- Mapping Distinct Bone Marrow Niche Populations and Their Differentiation Paths
- (2019) Samuel L. Wolock et al. Cell Reports
- Bmi1 restricts the adipogenic differentiation of bone marrow stromal cells to maintain the integrity of the hematopoietic stem cell niche
- (2019) Yuko Kato et al. EXPERIMENTAL HEMATOLOGY
- Haematopoietic stem cells in perisinusoidal niches are protected from ageing
- (2019) Mehmet Saçma et al. NATURE CELL BIOLOGY
- Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells
- (2019) Vanessa Frodermann et al. NATURE MEDICINE
- ROS-mediated PI3K activation drives mitochondrial transfer from stromal cells to hematopoietic stem cells in response to infection
- (2019) Jayna J. Mistry et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PDGFB-expressing mesenchymal stem cells improve human hematopoietic stem cell engraftment in immunodeficient mice
- (2019) Xiuxiu Yin et al. BONE MARROW TRANSPLANTATION
- Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization
- (2019) Chiara Baccin et al. NATURE CELL BIOLOGY
- Global Transcriptomic Profiling of the Bone Marrow Stromal Microenvironment during Postnatal Development, Aging, and Inflammation
- (2019) Patrick M. Helbling et al. Cell Reports
- Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms
- (2018) Maria Kleppe et al. CANCER CELL
- Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML
- (2018) Delfim Duarte et al. Cell Stem Cell
- PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ
- (2018) Bo Yu et al. Cell Stem Cell
- Imaging the Vascular Bone Marrow Niche During Inflammatory Stress
- (2018) Katrien Vandoorne et al. CIRCULATION RESEARCH
- Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche
- (2018) Maria Maryanovich et al. NATURE MEDICINE
- A mouse model for evaluation of efficacy and concomitant toxicity of anti-human CXCR4 therapeutics
- (2018) Maria José Costa et al. PLoS One
- Hepatic thrombopoietin is required for bone marrow hematopoietic stem cell maintenance
- (2018) Matthew Decker et al. SCIENCE
- CXCL12/CXCR4 Signaling Enhances Human PSC-Derived Hematopoietic Progenitor Function and Overcomes Early In Vivo Transplantation Failure
- (2018) Jennifer C. Reid et al. Stem Cell Reports
- Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance
- (2018) Karin Golan et al. Cell Stem Cell
- Distinct Bone Marrow Sources of Pleiotrophin Control Hematopoietic Stem Cell Maintenance and Regeneration
- (2018) Heather A. Himburg et al. Cell Stem Cell
- Endothelial transplantation rejuvenates aged hematopoietic stem cell function
- (2017) Michael G. Poulos et al. JOURNAL OF CLINICAL INVESTIGATION
- Bone marrow adipocytes promote the regeneration of stem cells and haematopoiesis by secreting SCF
- (2017) Bo O. Zhou et al. NATURE CELL BIOLOGY
- Differential cytokine contributions of perivascular haematopoietic stem cell niches
- (2017) Noboru Asada et al. NATURE CELL BIOLOGY
- Intercellular competition and the inevitability of multicellular aging
- (2017) Paul Nelson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Systemic Virus Infections Differentially Modulate Cell Cycle State and Functionality of Long-Term Hematopoietic Stem Cells In Vivo
- (2017) Christoph Hirche et al. Cell Reports
- Bioengineering of Humanized Bone Marrow Microenvironments in Mouse and Their Visualization by Live Imaging
- (2017) Diana Passaro et al. Jove-Journal of Visualized Experiments
- In middle-aged and old obese patients, training intervention reduces leptin level: A meta-analysis
- (2017) Ildikó Rostás et al. PLoS One
- TGF-β Inhibition Rescues Hematopoietic Stem Cell Defects and Bone Marrow Failure in Fanconi Anemia
- (2016) Haojian Zhang et al. Cell Stem Cell
- CD82/KAI1 Maintains the Dormancy of Long-Term Hematopoietic Stem Cells through Interaction with DARC-Expressing Macrophages
- (2016) Jin Hur et al. Cell Stem Cell
- Mesenchymal Inflammation Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Disease Evolution in Human Pre-leukemia
- (2016) Noemi A. Zambetti et al. Cell Stem Cell
- IFNα-mediated remodeling of endothelial cells in the bone marrow niche
- (2016) Áine M. Prendergast et al. HAEMATOLOGICA
- Extracellular matrix protein Matrilin-4 regulates stress-induced HSC proliferation via CXCR4
- (2016) Hannah Uckelmann et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Niche WNT5A regulates the actin cytoskeleton during regeneration of hematopoietic stem cells
- (2016) Christina Schreck et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Massive parallel RNA sequencing of highly purified mesenchymal elements in low-risk MDS reveals tissue-context-dependent activation of inflammatory programs
- (2016) S Chen et al. LEUKEMIA
- Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance
- (2016) K. Ito et al. SCIENCE
- Loss of Sfrp2 in the Niche Amplifies Stress-Induced Cellular Responses, and Impairs the In Vivo Regeneration of the Hematopoietic Stem Cell Pool
- (2016) Franziska Ruf et al. STEM CELLS
- Clec11a/osteolectin is an osteogenic growth factor that promotes the maintenance of the adult skeleton
- (2016) Rui Yue et al. eLife
- IFNα-mediated remodeling of endothelial cells in the bone marrow niche
- (2016) Áine M. Prendergast et al. HAEMATOLOGICA
- Enhanced Reconstitution of Human Erythropoiesis and Thrombopoiesis in an Immunodeficient Mouse Model with Kit Wv Mutations
- (2016) Ayano Yurino et al. Stem Cell Reports
- Improved Human Erythropoiesis and Platelet Formation in Humanized NSGW41 Mice
- (2016) Susann Rahmig et al. Stem Cell Reports
- Immunological Basis of Bone Marrow Failure after Allogeneic Hematopoietic Stem Cell Transplantation
- (2016) Stavroula Masouridi-Levrat et al. Frontiers in Immunology
- The Hematopoietic Niche in Myeloproliferative Neoplasms
- (2015) Annette H. Schmitt-Graeff et al. MEDIATORS OF INFLAMMATION
- Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal
- (2015) Melih Acar et al. NATURE
- Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells
- (2015) Dagmar Walter et al. NATURE
- Hematopoietic stem and progenitor cells regulate the regeneration of their niche by secreting Angiopoietin-1
- (2015) Bo O Zhou et al. eLife
- Nonirradiated NOD,B6.SCID Il2rγ−/− KitW41/W41 (NBSGW) Mice Support Multilineage Engraftment of Human Hematopoietic Cells
- (2015) Brian E. McIntosh et al. Stem Cell Reports
- Stroma-Derived Connective Tissue Growth Factor Maintains Cell Cycle Progression and Repopulation Activity of Hematopoietic Stem Cells In Vitro
- (2015) Rouzanna Istvánffy et al. Stem Cell Reports
- Inhibition of leukemia cell engraftment and disease progression in mice by osteoblasts
- (2014) M. Krevvata et al. BLOOD
- Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis
- (2014) S. Boettcher et al. BLOOD
- Estrogen Signaling Selectively Induces Apoptosis of Hematopoietic Progenitors and Myeloid Neoplasms without Harming Steady-State Hematopoiesis
- (2014) Abel Sánchez-Aguilera et al. Cell Stem Cell
- Kit Regulates HSC Engraftment across the Human-Mouse Species Barrier
- (2014) Kadriye Nehir Cosgun et al. Cell Stem Cell
- Myelodysplastic Cells in Patients Reprogram Mesenchymal Stromal Cells to Establish a Transplantable Stem Cell Niche Disease Unit
- (2014) Hind Medyouf et al. Cell Stem Cell
- Effective expansion of engrafted human hematopoietic stem cells in bone marrow of mice expressing human Jagged1
- (2014) Naoko Negishi et al. EXPERIMENTAL HEMATOLOGY
- Intrinsic Sex-Linked Variations in Osteogenic and Adipogenic Differentiation Potential of Bone Marrow Multipotent Stromal Cells
- (2014) Beth Bragdon et al. JOURNAL OF CELLULAR PHYSIOLOGY
- High c-Kit expression identifies hematopoietic stem cells with impaired self-renewal and megakaryocytic bias
- (2014) Joseph Y. Shin et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Clonal expansion capacity defines two consecutive developmental stages of long-term hematopoietic stem cells
- (2014) Tatyana Grinenko et al. JOURNAL OF EXPERIMENTAL MEDICINE
- G-CSF regulates hematopoietic stem cell activity, in part, through activation of Toll-like receptor signaling
- (2014) L G Schuettpelz et al. LEUKEMIA
- Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells
- (2014) Johanna Flach et al. NATURE
- Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms
- (2014) Lorena Arranz et al. NATURE
- Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts
- (2014) Aruna Kode et al. NATURE
- Oestrogen increases haematopoietic stem-cell self-renewal in females and during pregnancy
- (2014) Daisuke Nakada et al. NATURE
- Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone
- (2014) Anjali P. Kusumbe et al. NATURE
- Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells
- (2014) Meng Zhao et al. NATURE MEDICINE
- Age-related mutations associated with clonal hematopoietic expansion and malignancies
- (2014) Mingchao Xie et al. NATURE MEDICINE
- Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion
- (2014) Ingmar Bruns et al. NATURE MEDICINE
- Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence
- (2014) Giulio Genovese et al. NEW ENGLAND JOURNAL OF MEDICINE
- Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes
- (2014) Siddhartha Jaiswal et al. NEW ENGLAND JOURNAL OF MEDICINE
- Delayed Marrow Infusion in Mice Enhances Hematopoietic and Osteopoietic Engraftment by Facilitating Transient Expansion of the Osteoblastic Niche
- (2013) Roberta Marino et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Megakaryocytes promote murine osteoblastic HSC niche expansion and stem cell engraftment after radioablative conditioning
- (2013) T. S. Olson et al. BLOOD
- Protein Kinase C-β-Dependent Activation of NF-κB in Stromal Cells Is Indispensable for the Survival of Chronic Lymphocytic Leukemia B Cells In Vivo
- (2013) Gloria Lutzny et al. CANCER CELL
- Regional Localization within the Bone Marrow Influences the Functional Capacity of Human HSCs
- (2013) Borhane Guezguez et al. Cell Stem Cell
- CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance
- (2013) Adam Greenbaum et al. NATURE
- Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches
- (2013) Lei Ding et al. NATURE
- Arteriolar niches maintain haematopoietic stem cell quiescence
- (2013) Yuya Kunisaki et al. NATURE
- Differential regulation of myeloid leukemias by the bone marrow microenvironment
- (2013) Daniela S Krause et al. NATURE MEDICINE
- Endothelial Jagged-1 Is Necessary for Homeostatic and Regenerative Hematopoiesis
- (2013) Michael G. Poulos et al. Cell Reports
- FGF signaling facilitates postinjury recovery of mouse hematopoietic system
- (2012) M. Zhao et al. BLOOD
- FGF-2 expands murine hematopoietic stem and progenitor cells via proliferation of stromal cells, c-Kit activation, and CXCL12 down-regulation
- (2012) T. Itkin et al. BLOOD
- Myelopoiesis is regulated by osteocytes through Gs -dependent signaling
- (2012) K. Fulzele et al. BLOOD
- Hematopoietic stem cell mobilizing agents G-CSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation
- (2012) I G Winkler et al. LEUKEMIA
- Chronic inflammation as a promotor of mutagenesis in essential thrombocythemia, polycythemia vera and myelofibrosis. A human inflammation model for cancer development?
- (2012) Hans Carl Hasselbalch LEUKEMIA RESEARCH
- Endothelial and perivascular cells maintain haematopoietic stem cells
- (2012) Lei Ding et al. NATURE
- Pleiotrophin Regulates the Retention and Self-Renewal of Hematopoietic Stem Cells in the Bone Marrow Vascular Niche
- (2012) Heather A. Himburg et al. Cell Reports
- Stromal pleiotrophin regulates repopulation behavior of hematopoietic stem cells
- (2011) R. Istvanffy et al. BLOOD
- Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche
- (2011) Satoshi Yamazaki et al. CELL
- In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche
- (2011) Joji Fujisaki et al. NATURE
- Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo
- (2011) A. Rongvaux et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Engraftment of human hematopoietic stem cells is more efficient in female NOD/SCID/IL-2Rgc-null recipients
- (2010) F. Notta et al. BLOOD
- Loss of Cxcl12/Sdf-1 in adult mice decreases the quiescent state of hematopoietic stem/progenitor cells and alters the pattern of hematopoietic regeneration after myelosuppression
- (2010) Y.-S. Tzeng et al. BLOOD
- Novel markers of mesenchymal stem cells defined by genome-wide gene expression analysis of stromal cells from different sources
- (2010) Nikolas Kaltz et al. EXPERIMENTAL CELL RESEARCH
- Maf promotes osteoblast differentiation in mice by mediating the age-related switch in mesenchymal cell differentiation
- (2010) Keizo Nishikawa et al. JOURNAL OF CLINICAL INVESTIGATION
- Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
- (2010) Marc H. G. P. Raaijmakers et al. NATURE
- Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells
- (2010) Heather A Himburg et al. NATURE MEDICINE
- Early Radiation-induced Bone Marrow Injury
- (2009) Wencai Huang et al. ACADEMIC RADIOLOGY
- Interleukin-1 is essential for systemic inflammatory bone loss
- (2009) K Polzer et al. ANNALS OF THE RHEUMATIC DISEASES
- Restoration and reversible expansion of the osteoblastic hematopoietic stem cell niche after marrow radioablation
- (2009) M. Dominici et al. BLOOD
- Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with 9 1 and 4 1 integrins
- (2009) J. Grassinger et al. BLOOD
- Secreted Frizzled-Related Protein 1 Extrinsically Regulates Cycling Activity and Maintenance of Hematopoietic Stem Cells
- (2009) Jonas Renström et al. Cell Stem Cell
- Functional differences between two Tie2 ligands, angiopoietin-1 and -2, in regulation of adult bone marrow hematopoietic stem cells
- (2009) Yumiko Gomei et al. EXPERIMENTAL HEMATOLOGY
- Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment
- (2009) Olaia Naveiras et al. NATURE
- IFNα activates dormant haematopoietic stem cells in vivo
- (2009) Marieke A. G. Essers et al. NATURE
- Hematopoietic stem cell transplantation without irradiation
- (2009) Claudia Waskow et al. NATURE METHODS
- Efficient Hematopoietic Differentiation of Human Embryonic Stem Cells on Stromal Cells Derived from Hematopoietic Niches
- (2008) Maria H. Ledran et al. Cell Stem Cell
- Mesenchymal Stem Cells: Revisiting History, Concepts, and Assays
- (2008) Paolo Bianco et al. Cell Stem Cell
- Endogenous FGF-2 is critically important in PTH anabolic effects on bone
- (2008) Maria Giovanna Sabbieti et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche
- (2008) Cristina Lo Celso et al. NATURE
- Haematopoietic stem cell release is regulated by circadian oscillations
- (2008) Simón Méndez-Ferrer et al. NATURE
- Leukemic Cells Create Bone Marrow Niches That Disrupt the Behavior of Normal Hematopoietic Progenitor Cells
- (2008) Angela Colmone et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started