Manipulating niche composition limits damage to haematopoietic stem cells during Plasmodium infection

Dynamic responses of the haematopoietic stem cell niche to diverse stresses

(2020) Antoniana Batsivari et al.   NATURE CELL BIOLOGY

Machine learning predicts putative haematopoietic stem cells within large single-cell transcriptomics datasets

(2019) Fiona K. Hamey et al.   EXPERIMENTAL HEMATOLOGY

Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML

(2018) Delfim Duarte et al.   Cell Stem Cell

A Macrophage Colony-Stimulating-Factor-Producing γδ T Cell Subset Prevents Malarial Parasitemic Recurrence

(2018) Murad R. Mamedov et al.   IMMUNITY

Inhibition of ex vivo erythropoiesis by secreted and haemozoin-associated Plasmodium falciparum products

(2018) Daniela Boehm et al.   PARASITOLOGY

Proliferation dynamics of acute myeloid leukaemia and haematopoietic progenitors competing for bone marrow space

(2018) O. Akinduro et al.   Nature Communications

Plasmodium gametocytes display homing and vascular transmigration in the host bone marrow

(2018) Mariana De Niz et al.   Science Advances

The Majority of CD45– Ter119– CD31– Bone Marrow Cell Fraction Is of Hematopoietic Origin and Contains Erythroid and Lymphoid Progenitors

(2018) Philip E. Boulais et al.   IMMUNITY

Parathyroid hormone regulates fates of murine osteoblast precursors in vivo

(2017) Deepak H. Balani et al.   JOURNAL OF CLINICAL INVESTIGATION

Malaria

(2017) Margaret A. Phillips et al.   Nature Reviews Disease Primers

IFNα-mediated remodeling of endothelial cells in the bone marrow niche

(2016) Áine M. Prendergast et al.   HAEMATOLOGICA

Sepsis-Induced Osteoblast Ablation Causes Immunodeficiency

(2016) Asuka Terashima et al.   IMMUNITY

T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments

(2016) Edwin D. Hawkins et al.   NATURE

Distinct bone marrow blood vessels differentially regulate haematopoiesis

(2016) Tomer Itkin et al.   NATURE

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

IFN-γ protects hepatocytes againstPlasmodium vivaxinfection via LAP-like degradation of sporozoites

(2016) Patrick M. Lelliott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic Infection Depletes Hematopoietic Stem Cells through Stress-Induced Terminal Differentiation

(2016) Katie A. Matatall et al.   Cell Reports

Systematic tracking of altered haematopoiesis during sporozoite-mediated malaria development reveals multiple response points

(2016) Maria L. Vainieri et al.   Open Biology

IFNα-mediated remodeling of endothelial cells in the bone marrow niche

(2016) Áine M. Prendergast et al.   HAEMATOLOGICA

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Interferon-γ: The Jekyll and Hyde of Malaria

(2015) Thayer King et al.   PLoS Pathogens

In vivo time-lapse imaging shows diverse niche engagement by quiescent and naturally activated hematopoietic stem cells

(2014) N. M. Rashidi et al.   BLOOD

Cytotoxic CD8+ T Cells Stimulate Hematopoietic Progenitors by Promoting Cytokine Release from Bone Marrow Mesenchymal Stromal Cells

(2014) Christian M. Schürch et al.   Cell Stem Cell

Identification of Regulatory Networks in HSCs and Their Immediate Progeny via Integrated Proteome, Transcriptome, and DNA Methylome Analysis

(2014) Nina Cabezas-Wallscheid et al.   Cell Stem Cell

The bone marrow niche for haematopoietic stem cells

(2014) Sean J. Morrison et al.   NATURE

Plasmodium falciparum transmission stages accumulate in the human bone marrow

(2014) R. Joice et al.   Science Translational Medicine

Parathyroid Hormone Enhances Hematopoietic Expansion Via Upregulation of Cadherin-11 in Bone Marrow Mesenchymal Stromal Cells

(2014) Hisayuki Yao et al.   STEM CELLS

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

SLAM Family Markers Resolve Functionally Distinct Subpopulations of Hematopoietic Stem Cells and Multipotent Progenitors

(2013) Hideyuki Oguro et al.   Cell Stem Cell

PTH expands short-term murine hemopoietic stem cells through T cells

(2012) J.-Y. Li et al.   BLOOD

Intermittent parathyroid hormone administration converts quiescent lining cells to active osteoblasts

(2012) Sang Wan Kim et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Cutting Edge: LPS-Induced Emergency Myelopoiesis Depends on TLR4-Expressing Nonhematopoietic Cells

(2012) S. Boettcher et al.   JOURNAL OF IMMUNOLOGY

Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance

(2012) Ingrid G Winkler et al.   NATURE MEDICINE

Chronic Exposure to a TLR Ligand Injures Hematopoietic Stem Cells

(2011) B. L. Esplin et al.   JOURNAL OF IMMUNOLOGY

Transient Activation of Hematopoietic Stem and Progenitor Cells by IFNγ during Acute Bacterial Infection

(2011) Katherine C. MacNamara et al.   PLoS One

Endothelial Cells Are Essential for the Self-Renewal and Repopulation of Notch-Dependent Hematopoietic Stem Cells

(2010) Jason M. Butler et al.   Cell Stem Cell

Flk1-GFP BAC Tg Mice: An Animal Model for the Study of Blood Vessel Development

(2010) Hiroyuki ISHITOBI et al.   EXPERIMENTAL ANIMALS

Quiescent haematopoietic stem cells are activated by IFN-γ in response to chronic infection

(2010) Megan T. Baldridge et al.   NATURE

Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells

(2010) Hideki Kobayashi et al.   NATURE CELL BIOLOGY

Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential

(2009) D. G. Kent et al.   BLOOD

T Lymphocytes Amplify the Anabolic Activity of Parathyroid Hormone through Wnt10b Signaling

(2009) Masakazu Terauchi et al.   Cell Metabolism

Engraftment and Reconstitution of Hematopoiesis Is Dependent on VEGFR2-Mediated Regeneration of Sinusoidal Endothelial Cells

(2009) Andrea T. Hooper et al.   Cell Stem Cell

IFNα activates dormant haematopoietic stem cells in vivo

(2009) Marieke A. G. Essers et al.   NATURE

Intermittent PTH stimulates periosteal bone formation by actions on post-mitotic preosteoblasts

(2008) Robert L. Jilka et al.   BONE

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

(2008) Anne Wilson et al.   CELL

Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche

(2008) Cristina Lo Celso et al.   NATURE

Alteration of the Parasite Plasma Membrane and the Parasitophorous Vacuole Membrane during Exo-Erythrocytic Development of Malaria Parasites

(2008) Angelika Sturm et al.   PROTIST