S100A9-induced overexpression of PD-1/PD-L1 contributes to ineffective hematopoiesis in myelodysplastic syndromes

Immune dysregulation in myelodysplastic syndrome: Clinical features, pathogenesis and therapeutic strategies

(2018) Cong Wang et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Pro-inflammatory proteins S100A9 and tumor necrosis factor-α suppress erythropoietin elaboration in myelodysplastic syndromes

(2017) Thomas Cluzeau et al.   HAEMATOLOGICA

Novel therapeutic approach to improve hematopoiesis in low risk MDS by targeting MDSCs with the Fc-engineered CD33 antibody BI 836858

(2017) E A Eksioglu et al.   LEUKEMIA

The emerging role of immune checkpoint based approaches in AML and MDS

(2017) Prajwal Boddu et al.   LEUKEMIA & LYMPHOMA

Pro-inflammatory proteins S100A9 and tumor necrosis factor-α suppress erythropoietin elaboration in myelodysplastic syndromes

(2017) Thomas Cluzeau et al.   HAEMATOLOGICA

The NLRP3 inflammasome functions as a driver of the myelodysplastic syndrome phenotype

(2016) A. A. Basiorka et al.   BLOOD

Mesenchymal Inflammation Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Disease Evolution in Human Pre-leukemia

(2016) Noemi A. Zambetti et al.   Cell Stem Cell

Immune suppressive mechanisms in the tumor microenvironment

(2016) David H Munn et al.   CURRENT OPINION IN IMMUNOLOGY

The PD-1/PD-L1 axis contributes to immune metabolic dysfunctions of monocytes in chronic lymphocytic leukemia

(2016) M Qorraj et al.   LEUKEMIA

PD1 and PDL1 upregulation and survival after decitabine treatment in lower risk MDS

(2016) Sameem Abedin et al.   LEUKEMIA & LYMPHOMA

Rps14 haploinsufficiency causes a block in erythroid differentiation mediated by S100A8 and S100A9

(2016) Rebekka K Schneider et al.   NATURE MEDICINE

MYC regulates the antitumor immune response through CD47 and PD-L1

(2016) S. C. Casey et al.   SCIENCE

30 MDS GENETIC DAMAGE IS LINKED TO INFLAMMAGING INDUCED BONE MARROW HYPERGLYCEMIA

(2015) S. Wei et al.   LEUKEMIA RESEARCH

T-cell exhaustion in the tumor microenvironment

(2015) Y Jiang et al.   Cell Death & Disease

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

The Transcription Factor FoxO1 Sustains Expression of the Inhibitory Receptor PD-1 and Survival of Antiviral CD8+ T Cells during Chronic Infection

(2014) Matthew M. Staron et al.   IMMUNITY

Targeting IRAK1 as a Therapeutic Approach for Myelodysplastic Syndrome

(2013) Garrett W. Rhyasen et al.   CANCER CELL

Induction of myelodysplasia by myeloid-derived suppressor cells

(2013) Xianghong Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Expression of PD-L1, PD-L2, PD-1 and CTLA4 in myelodysplastic syndromes is enhanced by treatment with hypomethylating agents

(2013) H Yang et al.   LEUKEMIA

Myelodysplastic syndromes: revisiting the role of the bone marrow microenvironment in disease pathogenesis

(2012) Marc H. G. P. Raaijmakers   INTERNATIONAL JOURNAL OF HEMATOLOGY

Glucose-Induced β-Catenin Acetylation Enhances Wnt Signaling in Cancer

(2012) Ana Chocarro-Calvo et al.   MOLECULAR CELL

Deregulation of innate immune signaling in myelodysplastic syndromes is associated with deletion of chromosome arm 5q

(2011) Daniel T. Starczynowski et al.   CELL CYCLE

Chronic Immune Stimulation Might Act As a Trigger for the Development of Acute Myeloid Leukemia or Myelodysplastic Syndromes

(2011) Sigurdur Y. Kristinsson et al.   JOURNAL OF CLINICAL ONCOLOGY

Myelodysplastic syndromes and bone marrow microenvironment

(2011) Matteo Giovanni Della Porta   LEUKEMIA RESEARCH

Innate Immune Signaling in the Myelodysplastic Syndromes

(2010) Daniel T. Starczynowski et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia

(2010) Marc H. G. P. Raaijmakers et al.   NATURE

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

A critical role for phosphatase haplodeficiency in the selective suppression of deletion 5q MDS by lenalidomide

(2009) S. Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myelodysplastic syndromes

(2008) S. D. Nimer   BLOOD

Tumour necrosis factor-induced gene expression in human marrow stroma: clues to the pathophysiology of MDS?

(2008) Derek L. Stirewalt et al.   BRITISH JOURNAL OF HAEMATOLOGY

Relationship of SNCG, S100A4, S100A9 and LCN2 gene expression and DNA methylation in bladder cancer

(2008) Olusola Y. Dokun et al.   INTERNATIONAL JOURNAL OF CANCER

Inhibition of p38α MAPK disrupts the pathological loop of proinflammatory factor production in the myelodysplastic syndrome bone marrow microenvironment

(2008) Tony Navas et al.   LEUKEMIA & LYMPHOMA