Genotoxicity and Gene Expression in the Rat Lung Tissue following Instillation and Inhalation of Different Variants of Amorphous Silica Nanomaterials (aSiO2 NM)

A Guide for Using Transmission Electron Microscopy for Studying the Radiosensitizing Effects of Gold Nanoparticles In Vitro

(2021) Ioanna Tremi et al.   Nanomaterials

Pulmonary toxicity and gene expression changes after short-term inhalation exposure to surface-modified copper oxide nanoparticles

(2021) Ilse Gosens et al.   NanoImpact

Metabolomics profiling to investigate nanomaterial toxicity in vitro and in vivo

(2020) Anne Bannuscher et al.   Nanotoxicology

Nanomaterial categorization by surface reactivity: A case study comparing 35 materials with four different test methods

(2020) Aileen Bahl et al.   NanoImpact

Minimum Information for Reporting on the Comet Assay (MIRCA): recommendations for describing comet assay procedures and results

(2020) Peter Møller et al.   Nature Protocols

Cellular Toxicity and Immunological Effects of Carbon-based Nanomaterials

(2019) Xia Yuan et al.   Particle and Fibre Toxicology

Multifaceted Application of Silica Nanoparticles. A Review

(2019) Peerzada Gh Jeelani et al.   Silicon

An in-depth multi-omics analysis in RLE-6TN rat alveolar epithelial cells allows for nanomaterial categorization

(2019) Isabel Karkossa et al.   Particle and Fibre Toxicology

Fast, asymmetric and nonhomogeneous clearance of SiC nanoaerosol assessed by micro-particle-induced x-ray emission

(2018) Omar Lozano et al.   Nanomedicine

Phosphonate coating of SiO2 nanoparticles abrogates inflammatory effects and local changes of the lipid composition in the rat lung: a complementary bioimaging study

(2018) Mandy Großgarten et al.   Particle and Fibre Toxicology

The asbestos-carbon nanotube analogy: An update

(2018) Agnes B. Kane et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Regulatory and Mechanistic Actions of Glucocorticoids on T and Inflammatory Cells

(2018) Ana C. Liberman et al.   Frontiers in Endocrinology

Genotoxicity of amorphous silica nanoparticles: Status and prospects

(2018) Mostafa Yazdimamaghani et al.   Nanomedicine-Nanotechnology Biology and Medicine

Subacute inhalation toxicity study of synthetic amorphous silica nanoparticles in Sprague-Dawley rats

(2017) Jae Hoon Shin et al.   INHALATION TOXICOLOGY

Mechanistic understanding of nanoparticles’ interactions with extracellular matrix: the cell and immune system

(2017) Ayse Basak Engin et al.   Particle and Fibre Toxicology

Current and Potential Developments of Cortisol Aptasensing towards Point-of-Care Diagnostics (POTC)

(2017) Azrul Zainol Abidin et al.   SENSORS

Study of TiO 2 P25 nanoparticles genotoxicity on lung, blood and liver cells in lung overload and non-overload conditions after repeated respiratory exposure in rats

(2017) Charlène Relier et al.   TOXICOLOGICAL SCIENCES

A paradoxical response of the rat organism to long-term inhalation of silica-containing submicron (predominantly nanoscale) particles of a collected industrial aerosol at realistic exposure levels

(2017) Marina P. Sutunkova et al.   TOXICOLOGY

Moving into advanced nanomaterials. Toxicity of rutile TiO2 nanoparticles immobilized in nanokaolin nanocomposites on HepG2 cell line

(2017) Maria João Bessa et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Dependence between cytotoxicity and dynamic subcellular localization of up-conversion nanoparticles with different surface charges

(2017) Xiaodan Li et al.   RSC Advances

Colloidal Silica Particle Synthesis and Future Industrial Manufacturing Pathways: A Review

(2016) Emily D. E. R. Hyde et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Macrophages participate in local and systemic inflammation induced by amorphous silica nanoparticles through intratracheal instillation

(2016) Man Yang et al.   International Journal of Nanomedicine

Oxidative stress, inflammation, and DNA damage in multiple organs of mice acutely exposed to amorphous silica nanoparticles

(2016) Abderrahim Nemmar et al.   International Journal of Nanomedicine

Weak silica nanomaterial-induced genotoxicity can be explained by indirect DNA damage as shown by the OGG1-modified comet assay and genomic analysis

(2016) Stefan Pfuhler et al.   MUTAGENESIS

NanoGenotoxicology: present and the future

(2016) Shareen H. Doak et al.   MUTAGENESIS

Genotoxicity and gene expression analyses of liver and lung tissues of mice treated with titanium dioxide nanoparticles

(2016) Yan Li et al.   MUTAGENESIS

Characterization of in vitro genotoxic, cytotoxic and transcriptomic responses following exposures to amorphous silica of different sizes

(2016) Nathalie Decan et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Case studies putting the decision-making framework for the grouping and testing of nanomaterials (DF4nanoGrouping) into practice

(2016) Josje H.E. Arts et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Cytotoxic and genotoxic evaluation of different synthetic amorphous silica nanomaterials in the V79 cell line

(2016) Y Guichard et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Amine modification of nonporous silica nanoparticles reduces inflammatory response following intratracheal instillation in murine lungs

(2016) Angie S. Morris et al.   TOXICOLOGY LETTERS

Targeted metabolomics of nonhuman primate serum after exposure to ionizing radiation: potential tools for high-throughput biodosimetry

(2016) Evan L. Pannkuk et al.   RSC Advances

An in vitro alveolar macrophage assay for predicting the short-term inhalation toxicity of nanomaterials

(2016) Martin Wiemann et al.   JOURNAL OF NANOBIOTECHNOLOGY

Silica nanoparticle-generated ROS as a predictor of cellular toxicity: mechanistic insights and safety by design

(2016) Sean E. Lehman et al.   Environmental Science-Nano

Mitochondrial dysfunction in fatty acid oxidation disorders: insights from human and animal studies

(2015) M. Wajner et al.   BIOSCIENCE REPORTS

Industrial applications of nanoparticles

(2015) W. J. Stark et al.   CHEMICAL SOCIETY REVIEWS

In vitro and in vivo genotoxicity investigations of differently sized amorphous SiO2 nanomaterials

(2015) Elena Maser et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Genotoxicity and gene expression modulation of silver and titanium dioxide nanoparticles in mice

(2015) Nana Asare et al.   Nanotoxicology

Proteomic analysis of protein carbonylation: a useful tool to unravel nanoparticle toxicity mechanisms

(2015) Marc D. Driessen et al.   Particle and Fibre Toxicology

The use of the comet assay for the evaluation of the genotoxicity of nanomaterials

(2015) Amaya Azqueta et al.   Frontiers in Genetics

Tissue cohesion and the mechanics of cell rearrangement

(2014) R. David et al.   DEVELOPMENT

Genotoxicity of synthetic amorphous silica nanoparticles in rats following short-term exposure. Part 1: Oral route

(2014) Adeline Tarantini et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Genotoxicity of synthetic amorphous silica nanoparticles in rats following short-term exposure, part 2: Intratracheal instillation and intravenous injection

(2014) Yves Guichard et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Surface modifications of silica nanoparticles are crucial for their inert versus proinflammatory and immunomodulatory properties

(2014) Alessandrini et al.   International Journal of Nanomedicine

Application of short-term inhalation studies to assess the inhalation toxicity of nanomaterials

(2014) Robert Landsiedel et al.   Particle and Fibre Toxicology

Genotoxic evaluation of titanium dioxide nanoparticles in vivo and in vitro

(2014) Zhangjian Chen et al.   TOXICOLOGY LETTERS

Measuring oxidative damage to DNA and its repair with the comet assay

(2013) Andrew R. Collins   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Engineered nanomaterial uptake and tissue distribution: from cell to organism

(2013) Joerg Huwyler et al.   International Journal of Nanomedicine

Co-assessment of cell cycle and micronucleus frequencies demonstrates the influence of serum on thein vitrogenotoxic response to amorphous monodisperse silica nanoparticles of varying sizes

(2013) Laetitia Gonzalez et al.   Nanotoxicology

Mechanisms of genotoxicity. A review ofin vitroandin vivostudies with engineered nanoparticles

(2013) Zuzana Magdolenova et al.   Nanotoxicology

Inflammation and gene expression in the rat lung after instillation of silica nanoparticles: Effect of size, dispersion medium and particle surface charge

(2013) David M. Brown et al.   TOXICOLOGY LETTERS

Hazard identification of inhaled nanomaterials: making use of short-term inhalation studies

(2012) Christoph L. Klein et al.   ARCHIVES OF TOXICOLOGY

CuO Nanoparticle Interaction with Human Epithelial Cells: Cellular Uptake, Location, Export, and Genotoxicity

(2012) Zhenyu Wang et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Mechanism of cellular uptake of genotoxic silica nanoparticles

(2012) Qingshan Mu et al.   Particle and Fibre Toxicology

Wheat-derived arabinoxylan oligosaccharides with prebiotic effect increase satietogenic gut peptides and reduce metabolic endotoxemia in diet-induced obese mice

(2012) A M Neyrinck et al.   Nutrition & Diabetes

Role of intranuclear lipids in health and disease

(2011) Elisabetta Albi   Clinical Lipidology

Genotoxic effects of silver nanoparticles stimulated by oxidative stress in human normal bronchial epithelial (BEAS-2B) cells

(2011) Ha Ryong Kim et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

In vitro genotoxicity testing strategy for nanomaterials and the adaptation of current OECD guidelines

(2011) S.H. Doak et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Genotoxicity of inhaled nanosized TiO2 in mice

(2011) Hanna K. Lindberg et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Cellular toxicity of inorganic nanoparticles: Common aspects and guidelines for improved nanotoxicity evaluation

(2011) Stefaan J. Soenen et al.   Nano Today

Titanium dioxide nanoparticles exhibit genotoxicity and impair DNA repair activity in A549 cells

(2011) Mary-Line Jugan et al.   Nanotoxicology

In vivo genotoxicity study of titanium dioxide nanoparticles using comet assay following intratracheal instillation in rats

(2011) Masato Naya et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

The innate and adaptive immune response induced by alveolar macrophages exposed to ambient particulate matter

(2011) Ryohei Miyata et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Surface-Charge-Dependent Cell Localization and Cytotoxicity of Cerium Oxide Nanoparticles

(2010) Atul Asati et al.   ACS Nano

A framework for oligonucleotide microarray preprocessing

(2010) Benilton S. Carvalho et al.   BIOINFORMATICS

Impact of agglomeration state of nano- and submicron sized gold particles on pulmonary inflammation

(2010) Ilse Gosens et al.   Particle and Fibre Toxicology

NanoGenotoxicology: The DNA damaging potential of engineered nanomaterials

(2009) Neenu Singh et al.   BIOMATERIALS

Acylcarnitine profile analysis

(2009) Piero Rinaldo et al.   GENETICS IN MEDICINE

Changing the dose metric for inhalation toxicity studies: Short-term study in rats with engineered aerosolized amorphous silica nanoparticles

(2009) Christie M. Sayes et al.   INHALATION TOXICOLOGY

Interaction Between Nano-Anatase TiO2 and Liver DNA from Mice In Vivo

(2009) Na Li et al.   Nanoscale Research Letters

Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE-/- mice

(2009) Nicklas Jacobsen et al.   Particle and Fibre Toxicology

Development of a Short-Term Inhalation Test in the Rat Using Nano-Titanium Dioxide as a Model Substance

(2008) Lan Ma-Hock et al.   INHALATION TOXICOLOGY

Reproducible Comet Assay of Amorphous Silica Nanoparticles Detects No Genotoxicity

(2008) Clifford A. Barnes et al.   NANO LETTERS

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols