Genotoxicity of synthetic amorphous silica nanoparticles in rats following short-term exposure. Part 1: Oral route

Genotoxicity of synthetic amorphous silica nanoparticles in rats following short-term exposure, part 2: Intratracheal instillation and intravenous injection

(2014) Yves Guichard et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Amorphous silica nanoparticles impair vascular homeostasis and induce systemic inflammation

(2014) Abderrahim Nemmar et al.   International Journal of Nanomedicine

Sub-chronic toxicity study in rats orally exposed to nanostructured silica

(2014) Meike van der Zande et al.   Particle and Fibre Toxicology

The absorption, distribution, excretion and toxicity of mesoporous silica nanoparticles in mice following different exposure routes

(2013) Changhui Fu et al.   BIOMATERIALS

In vivo biodistribution and synergistic toxicity of silica nanoparticles and cadmium chloride in mice

(2013) Mingchun Guo et al.   JOURNAL OF HAZARDOUS MATERIALS

Genotoxicity evaluation of nanosized titanium dioxide, synthetic amorphous silica and multi-walled carbon nanotubes in human lymphocytes

(2013) Ana M. Tavares et al.   TOXICOLOGY IN VITRO

Presence of Nano-Sized Silica during In Vitro Digestion of Foods Containing Silica as a Food Additive

(2012) Ruud Peters et al.   ACS Nano

Effects of the Presence or Absence of a Protein Corona on Silica Nanoparticle Uptake and Impact on Cells

(2012) Anna Lesniak et al.   ACS Nano

Mechanism of transport of saquinavir-loaded nanostructured lipid carriers across the intestinal barrier

(2012) Ana Beloqui et al.   JOURNAL OF CONTROLLED RELEASE

Silica nanoparticles administered at the maximum tolerated dose induce genotoxic effects through an inflammatory reaction while gold nanoparticles do not

(2012) Thomas R. Downs et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Knowledge gaps in risk assessment of nanosilica in food: evaluation of the dissolution and toxicity of different forms of silica

(2012) Susan Dekkers et al.   Nanotoxicology

Effect of surface modification of silica nanoparticles on toxicity and cellular uptake by human peripheral blood lymphocytesin vitro

(2012) Anna Lankoff et al.   Nanotoxicology

In vitrotoxicity of amorphous silica nanoparticles in human colon carcinoma cells

(2012) Helge Gehrke et al.   Nanotoxicology

Mechanism of cellular uptake of genotoxic silica nanoparticles

(2012) Qingshan Mu et al.   Particle and Fibre Toxicology

The Shape Effect of Mesoporous Silica Nanoparticles on Biodistribution, Clearance, and Biocompatibility in Vivo

(2011) Xinglu Huang et al.   ACS Nano

A Single Instillation of Amorphous Silica Nanoparticles Induced Inflammatory Responses and Tissue Damage until Day 28 after Exposure

(2011) Eun-Jung Park et al.   JOURNAL OF HEALTH SCIENCE

Amorphous silica nanoparticles do not induce cytotoxicity, cell transformation or genotoxicity in Balb/3T3 mouse fibroblasts

(2011) Chiara Uboldi et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Induction of oxidative stress, DNA damage and apoptosis in mouse liver after sub-acute oral exposure to zinc oxide nanoparticles

(2011) Vyom Sharma et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Size and surface charge of gold nanoparticles determine absorption across intestinal barriers and accumulation in secondary target organs after oral administration

(2011) Carsten Schleh et al.   Nanotoxicology

Distribution of silver in rats following 28 days of repeated oral exposure to silver nanoparticles or silver acetate

(2011) Katrin Loeschner et al.   Particle and Fibre Toxicology

Models for oral uptake of nanoparticles in consumer products

(2011) Eleonore Fröhlich et al.   TOXICOLOGY

Toxicity of zinc oxide nanoparticles through oral route

(2011) Surekha Pasupuleti et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Sustained Small Interfering RNA Delivery by Mesoporous Silicon Particles

(2010) Takemi Tanaka et al.   CANCER RESEARCH

Cytotoxic and genotoxic effects of cylindrospermopsin in mice treated by gavage or intraperitoneal injection

(2010) Emmanuelle Bazin et al.   ENVIRONMENTAL TOXICOLOGY

Genotoxicity evaluation of amorphous silica nanoparticles of different sizes using the micronucleus and the plasmidlacZgene mutation assay

(2010) Margriet V. D. Z. Park et al.   Nanotoxicology

Exploring the aneugenic and clastogenic potential in the nanosize range: A549 human lung carcinoma cells and amorphous monodisperse silica nanoparticles as models

(2010) Laetitia Gonzalez et al.   Nanotoxicology

Activation of the inflammasome by amorphous silica and TiO2nanoparticles in murine dendritic cells

(2010) Meike Winter et al.   Nanotoxicology

Presence and risks of nanosilica in food products

(2010) Susan Dekkers et al.   Nanotoxicology

The nanosilica hazard: another variable entity

(2010) Dorota Napierska et al.   Particle and Fibre Toxicology

Nanotoxicity of pure silica mediated through oxidant generation rather than glutathione depletion in human lung epithelial cells

(2010) Mohd Javed Akhtar et al.   TOXICOLOGY

Titanium Dioxide Nanoparticles Induce DNA Damage and Genetic Instability In vivo in Mice

(2009) B. Trouiller et al.   CANCER RESEARCH

Silica nanoparticles as hepatotoxicants

(2009) Hikaru Nishimori et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Interaction of biodegradable nanoparticles with intestinal cells: The effect of surface hydrophilicity

(2009) Marie Gaumet et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Oxidative stress contributes to silica nanoparticle-induced cytotoxicity in human embryonic kidney cells

(2009) Fen Wang et al.   TOXICOLOGY IN VITRO

The impact of size on tissue distribution and elimination by single intravenous injection of silica nanoparticles

(2009) Minjung Cho et al.   TOXICOLOGY LETTERS

The biocompatibility of mesoporous silicates

(2008) Sarah P. Hudson et al.   BIOMATERIALS

Effect of Micro/Nano Silica Particle Feeding for Mice

(2008) Soo Jeong So et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Reproducible Comet Assay of Amorphous Silica Nanoparticles Detects No Genotoxicity

(2008) Clifford A. Barnes et al.   NANO LETTERS

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

Pulmonary response to intratracheal instillation of ultrafine versus fine titanium dioxide: role of particle surface area

(2008) Tina M Sager et al.   Particle and Fibre Toxicology

Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

(2008) M. Lundqvist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidative stress and pro-inflammatory responses induced by silica nanoparticles in vivo and in vitro

(2008) Eun-Jung Park et al.   TOXICOLOGY LETTERS