Mechanistic understanding of nanoparticles’ interactions with extracellular matrix: the cell and immune system

Innate Immune Cytokines, Fibroblast Phenotypes, and Regulation of Extracellular Matrix in Lung

(2017) Carl D. Richards   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Protein bio-corona: critical issue in immune nanotoxicology

(2016) Monica Neagu et al.   ARCHIVES OF TOXICOLOGY

Emerging aspects of nanotoxicology in health and disease: From agriculture and food sector to cancer therapeutics

(2016) Zoi Piperigkou et al.   FOOD AND CHEMICAL TOXICOLOGY

Nanoparticle-Delivered IRF5 siRNA Facilitates M1 to M2 Transition, Reduces Demyelination and Neurofilament Loss, and Promotes Functional Recovery After Spinal Cord Injury in Mice

(2016) Jun Li et al.   INFLAMMATION

Bifunctional Therapeutic High-Valence Silver-Pyridoxine Nanoparticles with Proliferative and Antibacterial Wound-Healing Activities

(2016) Sabarinathan Rangasamy et al.   Journal of Biomedical Nanotechnology

First in vivo detection and characterization of hyaluronan-coated extracellular vesicles in human synovial fluid

(2016) Anne-Mari Mustonen et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Macrophage-derived MCPIP1 mediates silica-induced pulmonary fibrosis via autophagy

(2016) Haijun Liu et al.   Particle and Fibre Toxicology

Persistence of cirrhosis is maintained by intrahepatic regulatory T cells that inhibit fibrosis resolution by regulating the balance of tissue inhibitors of metalloproteinases and matrix metalloproteinases

(2016) Xiaohui Zhang et al.   Translational Research

Selective binding and lateral clustering of α5β1 and αvβ3 integrins: Unraveling the spatial requirements for cell spreading and focal adhesion assembly

(2016) Viktoria Schaufler et al.   Cell Adhesion & Migration

Preparation and evaluation of PEGylated phospholipid membrane coated layered double hydroxide nanoparticles

(2016) Mina Yan et al.   Asian Journal of Pharmaceutical Sciences

Nanoparticle interaction with the immune system / Interakcije nanodelcev z imunskim sistemom

(2015) Veno Kononenko et al.   Arhiv za Higijenu Rada i Toksikologiju-Archives of Industrial Hygiene and Toxicology

The Role of Negative Charge in the Delivery of Quantum Dots to Neurons

(2015) Ryan Walters et al.   ASN Neuro

Paracrine co-delivery of TGF-β and IL-2 using CD4-targeted nanoparticles for induction and maintenance of regulatory T cells

(2015) Michael D. McHugh et al.   BIOMATERIALS

Matrix metalloproteinases contribute to the regulation of chemokine expression and pulmonary inflammation inCryptococcusinfection

(2015) O. Supasorn et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Specific hepatic delivery of procollagen α1(I) small interfering RNA in lipid-like nanoparticles resolves liver fibrosis

(2015) Carolina Jiménez Calvente et al.   HEPATOLOGY

Collagen nanofiber containing silver nanoparticles for improved wound-healing applications

(2015) Goutam Rath et al.   JOURNAL OF DRUG TARGETING

Silver nanoparticles of 70 nm and 20 nm affect differently the biology of human neutrophils

(2015) Michelle Poirier et al.   Journal of Immunotoxicology

Human Monocyte Response to S-Nitrosoglutathione-Loaded Nanoparticles: Uptake, Viability, and Transcriptome

(2015) Ramia Safar et al.   MOLECULAR PHARMACEUTICS

The functional dissection of the plasma corona of SiO2-NPs spots histidine rich glycoprotein as a major player able to hamper nanoparticle capture by macrophages

(2015) Chiara Fedeli et al.   Nanoscale

Proinflammatory Effects of Pyrogenic and Precipitated Amorphous Silica Nanoparticles in Innate Immunity Cells

(2015) Luisana Di Cristo et al.   TOXICOLOGICAL SCIENCES

Influence of Particle Size on Persistence and Clearance of Aerosolized Silver Nanoparticles in the Rat Lung

(2015) Donald S. Anderson et al.   TOXICOLOGICAL SCIENCES

Effects of amorphous silica coating on cerium oxide nanoparticles induced pulmonary responses

(2015) Jane Ma et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Hyaluronan regulates chemical allergen-induced IL-18 production in human keratinocytes

(2015) Dragana Nikitovic et al.   TOXICOLOGY LETTERS

Pulmonary surfactant augments cytotoxicity of silica nanoparticles: Studies on an in vitro air–blood barrier model

(2015) Jennifer Y Kasper et al.   Beilstein Journal of Nanotechnology

Comparative evaluation of the impact on endothelial cells induced by different nanoparticle structures and functionalization

(2015) Lisa Landgraf et al.   Beilstein Journal of Nanotechnology

Type VI Collagen Regulates Pericellular Matrix Properties, Chondrocyte Swelling, and Mechanotransduction in Mouse Articular Cartilage

(2015) Nicole A. Zelenski et al.   Arthritis & Rheumatology

M2 polarization enhances silica nanoparticle uptake by macrophages

(2015) Jessica Hoppstädter et al.   Frontiers in Pharmacology

Acceleration of Wound Healing byα-gal Nanoparticles Interacting with the Natural Anti-Gal Antibody

(2015) Uri Galili   Journal of Immunology Research

Different Interaction Modes of Biomolecules with Citrate-Capped Gold Nanoparticles

(2014) Shiyun Zhang et al.   ACS Applied Materials & Interfaces

Anthracycline-Dependent Cardiotoxicity and Extracellular Matrix Remodeling

(2014) Dragana Nikitovic et al.   CHEST

Exosomes as Immunotheranostic Nanoparticles

(2014) Natasha G et al.   CLINICAL THERAPEUTICS

A Molecular Switch for the Orientation of Epithelial Cell Polarization

(2014) David M. Bryant et al.   DEVELOPMENTAL CELL

Basement membrane influences intestinal epithelial cell growth and presents a barrier to the movement of macromolecules

(2014) Driton Vllasaliu et al.   EXPERIMENTAL CELL RESEARCH

Influence of HepG2 cell shape on nanoparticle uptake

(2014) Batirtze Prats-Mateu et al.   MICROSCOPY RESEARCH AND TECHNIQUE

Single particle tracking reveals biphasic transport during nanorod magnetophoresis through extracellular matrix

(2014) L. O. Mair et al.   Soft Matter

Comparative study of various growth factors and cytokines on type I collagen and hyaluronan production in human dermal fibroblasts

(2014) Mi-Sun Kim et al.   Journal of Cosmetic Dermatology

Polymer-Coated Nanoparticles Interacting with Proteins and Cells: Focusing on the Sign of the Net Charge

(2013) Dominik Hühn et al.   ACS Nano

Nanoparticles for localized delivery of hyaluronan oligomers towards regenerative repair of elastic matrix

(2013) Andrew Sylvester et al.   Acta Biomaterialia

Rapid binding of electrostatically stabilized iron oxide nanoparticles to THP-1 monocytic cells via interaction with glycosaminoglycans

(2013) Antje Ludwig et al.   BASIC RESEARCH IN CARDIOLOGY

Interaction between silver nanoparticles of 20 nm (AgNP20) and human neutrophils: induction of apoptosis and inhibition ofde novoprotein synthesis by AgNP20aggregates

(2013) Michelle Poirier et al.   JOURNAL OF APPLIED TOXICOLOGY

Development of novel aligned nanofibrous composite membranes for guided bone regeneration

(2013) M. Kharaziha et al.   Journal of the Mechanical Behavior of Biomedical Materials

Lumican affects tumor cell functions, tumor–ECM interactions, angiogenesis and inflammatory response

(2013) Dragana Nikitovic et al.   MATRIX BIOLOGY

Single-walled carbon nanotubes and graphene oxides induce autophagosome accumulation and lysosome impairment in primarily cultured murine peritoneal macrophages

(2013) Bin Wan et al.   TOXICOLOGY LETTERS

Scavenger Receptor Mediated Endocytosis of Silver Nanoparticles into J774A.1 Macrophages Is Heterogeneous

(2012) Hongyun Wang et al.   ACS Nano

Nitric Oxide–Releasing Nanoparticles Accelerate Wound Healing by Promoting Fibroblast Migration and Collagen Deposition

(2012) George Han et al.   AMERICAN JOURNAL OF PATHOLOGY

Titanium Dioxide Nanoparticles Induce Matrix Metalloprotease 1 in Human Pulmonary Fibroblasts Partly via an Interleukin-1β–Dependent Mechanism

(2012) Lucie Armand et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

MMP-2 Selectivity in Hydroxamate-Type Inhibitors

(2012) P. Serra et al.   CURRENT MEDICINAL CHEMISTRY

Glycosaminoglycans: from “cellular glue” to novel therapeutical agents

(2012) Nikos K Karamanos et al.   CURRENT OPINION IN PHARMACOLOGY

Glycosaminoglycans: key players in cancer cell biology and treatment

(2012) Nikos Afratis et al.   FEBS Journal

The Biology of Small Leucine-rich Proteoglycans in Bone Pathophysiology

(2012) Dragana Nikitovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nanoparticle Surface Charge Mediates the Cellular Receptors Used by Protein–Nanoparticle Complexes

(2012) Candace C. Fleischer et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Carbon nanoparticles induce ceramide- and lipid raft-dependent signalling in lung epithelial cells: a target for a preventive strategy against environmentally-induced lung inflammation

(2012) Henrike Peuschel et al.   Particle and Fibre Toxicology

WARP Interacts with Collagen VI-Containing Microfibrils in the Pericellular Matrix of Human Chondrocytes

(2012) Uwe Hansen et al.   PLoS One

Nanoparticle-Induced Exosomes Target Antigen-Presenting Cells to Initiate Th1-Type Immune Activation

(2012) Motao Zhu et al.   Small

Tissue Engineering and Regenerative Strategies to Replicate Biocomplexity of Vascular Elastic Matrix Assembly

(2012) Chris A. Bashur et al.   TISSUE ENGINEERING PART B-REVIEWS

Induction of pulmonary fibrosis by cerium oxide nanoparticles

(2012) Jane Y. Ma et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Cellular uptake, intracellular trafficking and cytotoxicity of silver nanoparticles

(2012) Raman Preet Singh et al.   TOXICOLOGY LETTERS

Intratracheally administered titanium dioxide or carbon black nanoparticles do not aggravate elastase-induced pulmonary emphysema in rats

(2012) Agnès Roulet et al.   BMC Pulmonary Medicine

N-acetylgalactosamine-functionalized dendrimers as hepatic cancer cell-targeted carriers

(2011) Scott H. Medina et al.   BIOMATERIALS

Cellular interactions of therapeutically delivered nanoparticles

(2011) Avnesh Kumari et al.   Expert Opinion on Drug Delivery

Effect of Different Forms of Anionic Nanoclays on Cytotoxicity

(2011) Miri Baek et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Modulation of collagen alignment by silver nanoparticles results in better mechanical properties in wound healing

(2011) Karen H.L. Kwan et al.   Nanomedicine-Nanotechnology Biology and Medicine

Surface charge of gold nanoparticles mediates mechanism of toxicity

(2011) Nicole M. Schaeublin et al.   Nanoscale

Penetration of Lipid Membranes by Gold Nanoparticles: Insights into Cellular Uptake, Cytotoxicity, and Their Relationship

(2010) Jiaqi Lin et al.   ACS Nano

Diffusion of Particles in the Extracellular Matrix: The Effect of Repulsive Electrostatic Interactions

(2010) Triantafyllos Stylianopoulos et al.   BIOPHYSICAL JOURNAL

S-Glutathionylation Regulates Inflammatory Activities of S100A9

(2010) Su Yin Lim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Engineered CH2 domains (nanoantibodies)

(2010) Dimiter S Dimitrov   mAbs

Breaching multiple barriers: leukocyte motility through venular walls and the interstitium

(2010) Sussan Nourshargh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Basement Membranes: Cell Scaffoldings and Signaling Platforms

(2010) P. D. Yurchenco   Cold Spring Harbor Perspectives in Biology

Lysyl oxidase resolves inflammation by reducing monocyte chemoattractant protein-1 in abdominal aortic aneurysm

(2009) Masahiko Onoda et al.   ATHEROSCLEROSIS

Selective Filtering of Particles by the Extracellular Matrix: An Electrostatic Bandpass

(2009) Oliver Lieleg et al.   BIOPHYSICAL JOURNAL

The extracellular matrix in development and morphogenesis: A dynamic view

(2009) Tania Rozario et al.   DEVELOPMENTAL BIOLOGY

The Molecular Basis of Vascular Lumen Formation in the Developing Mouse Aorta

(2009) Boris Strilić et al.   DEVELOPMENTAL CELL

The Extracellular Matrix: Not Just Pretty Fibrils

(2009) R. O. Hynes   SCIENCE

Oxidative stress and proinflammatory effects of carbon black and titanium dioxide nanoparticles: Role of particle surface area and internalized amount

(2009) Salik Hussain et al.   TOXICOLOGY

Effects of ultrafine TiO2 particles on gene expression profile in human keratinocytes without illumination: Involvement of extracellular matrix and cell adhesion

(2009) Katsuhide Fujita et al.   TOXICOLOGY LETTERS

Quantification of the force of nanoparticle-cell membrane interactions and its influence on intracellular trafficking of nanoparticles

(2008) Jaspreet K. Vasir et al.   BIOMATERIALS

Cell adhesion to agrin presented as a nanopatterned substrate is consistent with an interaction with the extracellular matrix and not transmembrane adhesion molecules

(2008) Tobias Wolfram et al.   BMC CELL BIOLOGY

Supramolecular Interactions in the Dermo-epidermal Junction Zone

(2008) Daniela Villone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protection from High Fat Diet-induced Increase in Ceramide in Mice Lacking Plasminogen Activator Inhibitor 1

(2008) Charmi Shah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induction of mesothelioma in p53+/− mouse by intraperitoneal application of multi-wall carbon nanotube

(2008) Atsuya Takagi et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

From cells to organs: building polarized tissue

(2008) David M. Bryant et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The extracellular matrix of the spleen as a potential organizer of immune cell compartments

(2008) Zerina Lokmic et al.   SEMINARS IN IMMUNOLOGY

Transforming Growth Factor Beta 1 and Hyaluronan Oligomers Synergistically Enhance Elastin Matrix Regeneration by Vascular Smooth Muscle Cells

(2008) Chandrasekhar R. Kothapalli et al.   TISSUE ENGINEERING PART A

Breaching the basement membrane: who, when and how?

(2008) R. Grant Rowe et al.   TRENDS IN CELL BIOLOGY

Carbon nanoparticle-induced lung epithelial cell proliferation is mediated by receptor-dependent Akt activation

(2007) Klaus Unfried et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY