Pathological Neuroinflammatory Conversion of Reactive Astrocytes Is Induced by Microglia and Involves Chromatin Remodeling

Reactive astrocyte nomenclature, definitions, and future directions

(2021) Carole Escartin et al.   NATURE NEUROSCIENCE

Interaction of Microglia and Astrocytes in the Neurovascular Unit

(2020) Li-rong Liu et al.   Frontiers in Immunology

Crosstalk Between Astrocytes and Microglia: An Overview

(2020) Agata Matejuk et al.   Frontiers in Immunology

Synergistic Enhancement of Cancer Therapy Using HDAC Inhibitors: Opportunity for Clinical Trials

(2020) Lourdes Hontecillas-Prieto et al.   Frontiers in Genetics

Astrocyte function from information processing to cognition and cognitive impairment

(2019) Mirko Santello et al.   NATURE NEUROSCIENCE

Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells

(2019) Rodolfo Soria-Castro et al.   Journal of Immunology Research

Astrocyte Heterogeneity: Impact to Brain Aging and Disease

(2019) Isadora Matias et al.   Frontiers in Aging Neuroscience

Detrimental Effects of HMGB-1 Require Microglial-Astroglial Interaction: Implications for the Status Epilepticus -Induced Neuroinflammation

(2019) Gerardo Rosciszewski et al.   Frontiers in Cellular Neuroscience

Epigenetic regulation of astrocyte function in neuroinflammation and neurodegeneration

(2018) Matthew Neal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome

(2018) Brian T. Weinert et al.   CELL

Spinal Cord Injury Scarring and Inflammation: Therapies Targeting Glial and Inflammatory Responses

(2018) Michael B. Orr et al.   Neurotherapeutics

Histone Lysine and Genomic Targets of Histone Acetyltransferases in Mammals

(2018) Anne K. Voss et al.   BIOESSAYS

Histone Deacetylase Inhibitors: A Therapeutic Key in Neurological Disorders?

(2018) Malgorzata Ziemka-Nalecz et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Clonal Glial Response in a Multiple Sclerosis Mouse Model

(2018) Ana Bribian et al.   Frontiers in Cellular Neuroscience

Inhibition of histone deacetylase 1 or 2 reduces induced cytokine expression in microglia through a protein synthesis independent mechanism

(2017) Benjamin S. Durham et al.   JOURNAL OF NEUROCHEMISTRY

Microglia amplify inflammatory activation of astrocytes in manganese neurotoxicity

(2017) Kelly S. Kirkley et al.   Journal of Neuroinflammation

Toll-Like Receptor 4 (TLR4) and Triggering Receptor Expressed on Myeloid Cells-2 (TREM-2) Activation Balance Astrocyte Polarization into a Proinflammatory Phenotype

(2017) Gerardo Rosciszewski et al.   MOLECULAR NEUROBIOLOGY

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Differentiation of Inflammation-Responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells

(2017) Renata Santos et al.   Stem Cell Reports

The development prospection of HDAC inhibitors as a potential therapeutic direction in Alzheimer’s disease

(2017) Shuang-shuang Yang et al.   Translational Neurodegeneration

Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease

(2016) H. Lian et al.   JOURNAL OF NEUROSCIENCE

Astrocyte scar formation aids central nervous system axon regeneration

(2016) Mark A. Anderson et al.   NATURE

Astroglial heterogeneity: merely a neurobiological question? Or an opportunity for neuroprotection and regeneration after brain injury?

(2016) AlbertoJavier Ramos   Neural Regeneration Research

H3K9me3-Dependent Heterochromatin: Barrier to Cell Fate Changes

(2016) Justin S. Becker et al.   TRENDS IN GENETICS

Isolation and Characterization of Ischemia-Derived Astrocytes (IDAs) with Ability to Transactivate Quiescent Astrocytes

(2016) Alejandro Villarreal et al.   Frontiers in Cellular Neuroscience

Astrocytes: a central element in neurological diseases

(2015) Milos Pekny et al.   ACTA NEUROPATHOLOGICA

NFκB-Activated Astroglial Release of Complement C3 Compromises Neuronal Morphology and Function Associated with Alzheimer’s Disease

(2015) Hong Lian et al.   NEURON

Functional regeneration beyond the glial scar

(2014) Jared M. Cregg et al.   EXPERIMENTAL NEUROLOGY

S100B protein activates a RAGE-dependent autocrine loop in astrocytes: implications for its role in the propagation of reactive gliosis

(2014) Alejandro Villarreal et al.   JOURNAL OF NEUROCHEMISTRY

Histone core modifications regulating nucleosome structure and dynamics

(2014) Peter Tessarz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Proinflammatory RAGE/NF-κB Pathway Is Involved in Neuronal Damage and Reactive Gliosis in a Model of Sleep Apnea by Intermittent Hypoxia

(2014) Maria Florencia Angelo et al.   PLoS One

Microglia change from a reactive to an age-like phenotype with the time in culture

(2014) Cláudia Caldeira et al.   Frontiers in Cellular Neuroscience

Writers and Readers of Histone Acetylation: Structure, Mechanism, and Inhibition

(2014) R. Marmorstein et al.   Cold Spring Harbor Perspectives in Biology

Astrogliosis

(2014) Michael V. Sofroniew   Cold Spring Harbor Perspectives in Biology

Nuclear Factor  B-Dependent Histone Acetylation is Specifically Involved in Persistent Forms of Memory

(2013) N. Federman et al.   JOURNAL OF NEUROSCIENCE

Emerging roles of astrocytes in neural circuit development

(2013) Laura E. Clarke et al.   NATURE REVIEWS NEUROSCIENCE

Heterogeneity of reactive astrocytes

(2013) Mark A. Anderson et al.   NEUROSCIENCE LETTERS

Analysis of the RelA:CBP/p300 Interaction Reveals Its Involvement in NF-κB-Driven Transcription

(2013) Sulakshana P. Mukherjee et al.   PLOS BIOLOGY

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

S100B alters neuronal survival and dendrite extension via RAGE-mediated NF-κB signaling

(2011) Alejandro Villarreal et al.   JOURNAL OF NEUROCHEMISTRY

Cross talk between activation of microglia and astrocytes in pathological conditions in the central nervous system

(2011) W. Liu et al.   LIFE SCIENCES

Phenotypically aberrant astrocytes that promote motoneuron damage in a model of inherited amyotrophic lateral sclerosis

(2011) P. Diaz-Amarilla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonhistone protein acetylation as cancer therapy targets

(2010) Brahma N Singh et al.   Expert Review of Anticancer Therapy

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Intermittent hypoxia during sleep induces reactive gliosis and limited neuronal death in rats: implications for sleep apnea

(2009) Rolando Xavier Aviles-Reyes et al.   JOURNAL OF NEUROCHEMISTRY

Multiple roles of HDAC inhibition in neurodegenerative conditions

(2009) De-Maw Chuang et al.   TRENDS IN NEUROSCIENCES

Molecular dissection of reactive astrogliosis and glial scar formation

(2009) Michael V. Sofroniew   TRENDS IN NEUROSCIENCES

The Mystery and Magic of Glia: A Perspective on Their Roles in Health and Disease

(2008) Ben A. Barres   NEURON