Inhibition of histone deacetylase 1 or 2 reduces induced cytokine expression in microglia through a protein synthesis independent mechanism

The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation

(2016) Anja Henn   ALTEX-Alternatives to Animal Experimentation

Acetylome Analysis Reveals Diverse Functions of Lysine Acetylation inMycobacterium tuberculosis

(2014) Fengying Liu et al.   MOLECULAR & CELLULAR PROTEOMICS

The physiological roles of histone deacetylase (HDAC) 1 and 2: complex co-stars with multiple leading parts

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Histone deacetylase 1 and 2 are essential for normal T-cell development and genomic stability in mice

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Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability

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Histone deacetylase isoforms regulate innate immune responses by deacetylating mitogen-activated protein kinase phosphatase-1

(2013) Y. Jeong et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Oral Administration of Histone Deacetylase Inhibitor MS-275 Ameliorates Neuroinflammation and Cerebral Amyloidosis and Improves Behavior in a Mouse Model

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Histone deacetylase inhibitors suppress immune activation in primary mouse microglia

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A comparative review of cell culture systems for the study of microglial biology in Alzheimer’s disease

(2012) Branden Stansley et al.   Journal of Neuroinflammation

Induction of differentiation and apoptosis in leukaemic cell lines by the novel benzamide family histone deacetylase 2 and 3 inhibitor MI-192

(2012) Marjorie Boissinot et al.   LEUKEMIA RESEARCH

Neuroprotective effects of valproic acid following transient global ischemia in rats

(2012) Aiguo Xuan et al.   LIFE SCIENCES

Modelling Neuroinflammation In Vitro: A Tool to Test the Potential Neuroprotective Effect of Anti-Inflammatory Agents

(2012) Núria Gresa-Arribas et al.   PLoS One

Proteomic Analysis of Lysine Acetylation Sites in Rat Tissues Reveals Organ Specificity and Subcellular Patterns

(2012) Alicia Lundby et al.   Cell Reports

Histone deacetylase inhibitors block nuclear factor-κB-dependent transcription by interfering with RNA polymerase II recruitment

(2011) Ryohei Furumai et al.   CANCER SCIENCE

Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis

(2011) Jennifer Jurkin et al.   CELL CYCLE

Tetrandrine suppresses amyloid-β-induced inflammatory cytokines by inhibiting NF-κB pathway in murine BV2 microglial cells

(2011) Fu Qian He et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

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(2011) Na'ama Shein et al.   MOLECULAR MEDICINE

Acetylation of p65 at lysine 314 is important for late NF-κB-dependent gene expression

(2010) Karin M Rothgiesser et al.   BMC GENOMICS

Mechanisms Underlying Inflammation in Neurodegeneration

(2010) Christopher K. Glass et al.   CELL

Beyond Histone and Deacetylase: An Overview of Cytoplasmic Histone Deacetylases and Their Nonhistone Substrates

(2010) Ya-Li Yao et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Histone Deacetylase Inhibitors Suppress the Expression of Inflammatory and Innate Immune Response Genes in Human Microglia and Astrocytes

(2010) Hyeon-Sook Suh et al.   Journal of Neuroimmune Pharmacology

Chemical phylogenetics of histone deacetylases

(2010) James E Bradner et al.   Nature Chemical Biology

MS-275, an histone deacetylase inhibitor, reduces the inflammatory reaction in rat experimental autoimmune neuritis

(2010) Z.Y. Zhang et al.   NEUROSCIENCE

Histone deacetylase (HDAC) inhibitors reduce the glial inflammatory response in vitro and in vivo

(2009) Giuseppe Faraco et al.   NEUROBIOLOGY OF DISEASE

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors

(2008) Nagma Khan et al.   BIOCHEMICAL JOURNAL

HDAC inhibitor increases histone H3 acetylation and reduces microglia inflammatory response following traumatic brain injury in rats

(2008) Bin Zhang et al.   BRAIN RESEARCH

Differential migration, LPS-induced cytokine, chemokine, and NO expression in immortalized BV-2 and HAPI cell lines and primary microglial cultures

(2008) Ryan J. Horvath et al.   JOURNAL OF NEUROCHEMISTRY

Good statistical practice in pharmacology Problem 2

(2007) M Lew   BRITISH JOURNAL OF PHARMACOLOGY