β-Patchoulene Ameliorates Water Transport and the Mucus Barrier in 5-Fluorouracil-Induced Intestinal Mucositis Rats via the cAMP/PKA/CREB Signaling Pathway

Patchouli alcohol attenuates 5-fluorouracil-induced intestinal mucositis via TLR2/MyD88/NF-kB pathway and regulation of microbiota

(2020) Jiazhen Wu et al.   BIOMEDICINE & PHARMACOTHERAPY

Astragalus polysaccharides alleviates LPS‐induced inflammation via the NF‐κB/MAPK signaling pathway

(2020) Na Dong et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Oral mucositis: the hidden side of cancer therapy

(2020) Claudio Pulito et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

β-patchoulene simultaneously ameliorated dextran sulfate sodium-induced colitis and secondary liver injury in mice via suppressing colonic leakage and flora imbalance

(2020) Yuhong Liu et al.   BIOCHEMICAL PHARMACOLOGY

Complex roles of cAMP–PKA–CREB signaling in cancer

(2020) Hongying Zhang et al.   Experimental Hematology & Oncology

Patchouli oil ameliorates 5-fluorouracil-induced intestinal mucositis in rats via protecting intestinal barrier and regulating water transport

(2019) Yuxuan Gan et al.   JOURNAL OF ETHNOPHARMACOLOGY

Mucins, Mucus, and Goblet Cells

(2018) Jonathan Ma et al.   CHEST

CPT-11-Induced Delayed Diarrhea Develops via Reduced Aquaporin-3 Expression in the Colon

(2018) Risako Kon et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Protective role of β-patchoulene from Pogostemon cablin against indomethacin-induced gastric ulcer in rats: Involvement of anti-inflammation and angiogenesis

(2018) Jia-Zhen Wu et al.   PHYTOMEDICINE

Suppression of Intestinal Epithelial Cell Chemokine Production by Lactobacillus rhamnosus R0011 and Lactobacillus helveticus R0389 Is Mediated by Secreted Bioactive Molecules

(2018) Michael P. Jeffrey et al.   Frontiers in Immunology

Aquaporin-3 in Cancer

(2017) Saw Marlar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Administration of probiotic mixture DM#1 ameliorated 5-fluorouracil–induced intestinal mucositis and dysbiosis in rats

(2017) Yan Tang et al.   NUTRITION

Moxibustion eases chronic inflammatory visceral pain through regulating MEK, ERK and CREB in rats

(2017) Zhi-Yuan Li et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Irinotecan- and 5-fluorouracil-induced intestinal mucositis: insights into pathogenesis and therapeutic perspectives

(2016) Ronaldo A. Ribeiro et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Anti-inflammatory activity of β-patchoulene isolated from patchouli oil in mice

(2016) Zhenbiao Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The intestinal epithelial barrier: a therapeutic target?

(2016) Matthew A. Odenwald et al.   Nature Reviews Gastroenterology & Hepatology

5-HT1D receptor inhibits renal sympathetic neurotransmission by nitric oxide pathway in anesthetized rats

(2015) José-Ángel García-Pedraza et al.   VASCULAR PHARMACOLOGY

Management of Mucositis During Chemotherapy: From Pathophysiology to Pragmatic Therapeutics

(2015) Ysabella Z. A. Van Sebille et al.   Current Oncology Reports

Identification of Estrogen Response Element in Aquaporin-3 Gene that Mediates Estrogen-induced Cell Migration and Invasion in Estrogen Receptor-positive Breast Cancer

(2015) Yi-Ting Huang et al.   Scientific Reports

Systematic review: the role of the gut microbiota in chemotherapy- or radiation-induced gastrointestinal mucositis - current evidence and potential clinical applications

(2014) Y. Touchefeu et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

VPAC1 receptors regulate intestinal secretion and muscle contractility by activating cholinergic neurons in guinea pig jejunum

(2014) Candice Fung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system

(2014) Thaher Pelaseyed et al.   IMMUNOLOGICAL REVIEWS

Intestinal Inflammation and Mucosal Barrier Function

(2014) Fermín Sánchez de Medina et al.   INFLAMMATORY BOWEL DISEASES

Aquaporin 3 promotes epithelial-mesenchymal transition in gastric cancer

(2014) Jia Chen et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Isolation of (-)-Patchouli Alcohol from Patchouli Oil by Fractional Distillation and Crystallization

(2014) ZQ Su et al.   TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH

Rhubarb Tannins Extract Inhibits the Expression of Aquaporins 2 and 3 in Magnesium Sulphate-Induced Diarrhoea Model

(2014) Chunfang Liu et al.   Biomed Research International

The complexity of NF-κB signaling in inflammation and cancer

(2013) Bastian Hoesel et al.   Molecular Cancer

Emerging evidence on the pathobiology of mucositis

(2013) Noor Al-Dasooqi et al.   SUPPORTIVE CARE IN CANCER

Origin and concept of medicine food homology and its application in modern functional foods

(2013) Yan Hou et al.   Food & Function

Water channel proteins in the gastrointestinal tract

(2012) Umberto Laforenza   MOLECULAR ASPECTS OF MEDICINE

Intestinal barrier function in health and gastrointestinal disease

(2012) M. Camilleri et al.   NEUROGASTROENTEROLOGY AND MOTILITY

The molecular biology of memory: cAMP, PKA, CRE, CREB-1, CREB-2, and CPEB

(2012) Eric R Kandel   Molecular Brain

Targeting CREB for Cancer Therapy: Friend or Foe

(2010) X. Xiao et al.   CURRENT CANCER DRUG TARGETS

Bile acid regulates MUC2 transcription in colon cancer cells via positive EGFR/PKC/Ras/ERK/CREB, PI3K/Akt/IκB/NF-κB and p38/MSK1/CREB pathways and negative JNK/c-Jun/AP-1 pathway

(2010) Kim   INTERNATIONAL JOURNAL OF ONCOLOGY

The Role of the Transcription Factor CREB in Immune Function

(2010) A. Y. Wen et al.   JOURNAL OF IMMUNOLOGY

Intestinal barrier function: Molecular regulation and disease pathogenesis

(2009) Katherine R. Groschwitz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Review: Chemotherapy-induced diarrhea: pathophysiology, frequency and guideline-based management

(2009) Alexander Stein et al.   Therapeutic Advances in Medical Oncology