Rhubarb Tannins Extract Inhibits the Expression of Aquaporins 2 and 3 in Magnesium Sulphate-Induced Diarrhoea Model

Rheinanthrone, a metabolite of sennoside A, triggers macrophage activation to decrease aquaporin-3 expression in the colon, causing the laxative effect of rhubarb extract

(2014) Risako Kon et al.   JOURNAL OF ETHNOPHARMACOLOGY

5-Fluorouracil Induces Diarrhea with Changes in the Expression of Inflammatory Cytokines and Aquaporins in Mouse Intestines

(2013) Hiroyasu Sakai et al.   PLoS One

Inhibition of Aquaporin-3 Water Channel in the Colon Induces Diarrhea

(2012) Nobutomo Ikarashi et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Berberine increases the expression of NHE3 and AQP4 in sennosideA-induced diarrhoea model

(2012) Yongguo Zhang et al.   FITOTERAPIA

Water channel proteins in the gastrointestinal tract

(2012) Umberto Laforenza   MOLECULAR ASPECTS OF MEDICINE

Effects of Magnesium Sulphate Administration on Aquaporin 3 in Rat Gastrointestinal Tract

(2011) Nobutomo Ikarashi et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Levels of Tannins and Flavonoids in Medicinal Plants: Evaluating Bioprospecting Strategies

(2011) Clarissa Fernanda de Queiroz Siqueira et al.   Evidence-based Complementary and Alternative Medicine

Antimicrobial, Cytotoxic and Antioxidant Activities and Determination of the Total Tannin Content of Bark Extracts Endopleura uchi

(2011) Flávio A. S. Politi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inhibition of Ca2+-activated Cl− channels by gallotannins as a possible molecular basis for health benefits of red wine and green tea

(2010) Wan Namkung et al.   FASEB JOURNAL

Antidiarrheal activity of extracts and compound from Trilepisium madagascariense stem bark

(2010) Jules-Roger Kuiate et al.   INDIAN JOURNAL OF PHARMACOLOGY

The diarrhoeogenic and antidiarrhoeal bidirectional effects of rhubarb and its potential mechanism

(2010) Yi Qin et al.   JOURNAL OF ETHNOPHARMACOLOGY

Reciprocal Regulation of Aquaporin-2 Abundance and Degradation by Protein Kinase A and p38-MAP Kinase

(2010) P. I. Nedvetsky et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A mechanism by which the osmotic laxative magnesium sulphate increases the intestinal aquaporin 3 expression in HT-29 cells

(2010) Nobutomo Ikarashi et al.   LIFE SCIENCES

A Plant-Derived Hydrolysable Tannin Inhibits CFTR Chloride Channel: A Potential Treatment of Diarrhea

(2010) Nisa Wongsamitkul et al.   PHARMACEUTICAL RESEARCH

Immunomodulation of Rheum tanguticum polysaccharide (RTP) on the immunosuppressive effects of dexamethasone (DEX) on the treatment of colitis in rats induced by 2,4,6-trinitrobenzene sulfonic acid

(2009) Li Liu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Antidiarrhoeal activity of Geranium incanum Burm. f. (Geraniaceae) leaf aqueous extract in mice

(2009) G.J. Amabeoku   JOURNAL OF ETHNOPHARMACOLOGY

Tannins: Current knowledge of food sources, intake, bioavailability and biological effects

(2009) José Serrano et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The beneficial effect of Rheum tanguticum polysaccharide on protecting against diarrhea, colonic inflammation and ulceration in rats with TNBS-induced colitis: The role of macrophage mannose receptor in inflammation and immune response

(2008) Li Liu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY