Intestinal barrier function in health and gastrointestinal disease

The Expression and the Cellular Distribution of the Tight Junction Proteins Are Altered in Irritable Bowel Syndrome Patients With Differences According to the Disease Subtype

(2011) Nathalie Bertiaux-Vandaële et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Tight Junction Pore and Leak Pathways: A Dynamic Duo

(2011) Le Shen et al.   Annual Review of Physiology

Impaired Uptake of Serotonin by Platelets From Patients With Irritable Bowel Syndrome Correlates With Duodenal Immune Activation

(2011) Stephen Foley et al.   GASTROENTEROLOGY

Identifying and testing candidate genes underlying the inflammatory basis of irritable bowel syndrome

(2011) R. Spiller et al.   GUT

Bifidobacteria can protect from enteropathogenic infection through production of acetate

(2011) Shinji Fukuda et al.   NATURE

Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis

(2011) Charles L. Bevins et al.   NATURE REVIEWS MICROBIOLOGY

Zonulin and Its Regulation of Intestinal Barrier Function: The Biological Door to Inflammation, Autoimmunity, and Cancer

(2011) Alessio Fasano   PHYSIOLOGICAL REVIEWS

Epithelial Gaps in a Rodent Model of Inflammatory Bowel Disease: A Quantitative Validation Study

(2011) Julia J Liu et al.   Clinical and Translational Gastroenterology

Randomised clinical trial: the effects of perioperative probiotic treatment on barrier function and post-operative infectious complications in colorectal cancer surgery - a double-blind study

(2010) Z. Liu et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Lactobacillus plantarum ameliorates colonic epithelial barrier dysfunction by modulating the apical junctional complex and PepT1 in IL-10 knockout mice

(2010) Hong-Qi Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Lactobacillus plantarum MB452 enhances the function of the intestinal barrier by increasing the expression levels of genes involved in tight junction formation

(2010) Rachel C Anderson et al.   BMC MICROBIOLOGY

Subjects with Diarrhea-Predominant IBS Have Increased Rectal Permeability Responsive to Tryptase

(2010) Jae Woong Lee et al.   DIGESTIVE DISEASES AND SCIENCES

The active Zot domain (aa 288–293) increases ZO-1 and myosin 1C serine/threonine phosphorylation, alters interaction between ZO-1 and its binding partners, and induces tight junction disassembly through proteinase activated receptor 2 activation

(2010) Simeon E. Goldblum et al.   FASEB JOURNAL

Genetic Risk Factors for Post-Infectious Irritable Bowel Syndrome Following a Waterborne Outbreak of Gastroenteritis

(2010) Alexandra–Chloé Villani et al.   GASTROENTEROLOGY

The Relationship between Small-Intestinal Bacterial Overgrowth and Intestinal Permeability in Patients with Irritable Bowel Syndrome

(2010) Jung Ho Park et al.   Gut and Liver

Paracellular permeability is increased by basal lipopolysaccharide in a primary culture of colonic epithelial cells; an effect prevented by an activator of Toll-like receptor-2

(2010) Peter J. Hanson et al.   Innate Immunity

Segmental expression of claudin proteins correlates with tight junction barrier properties in rat intestine

(2010) Alexander G. Markov et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY

The intestinal barrier and its regulation by neuroimmune factors

(2010) å. v. Keita et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Effect of mesalazine on mucosal immune biomarkers in irritable bowel syndrome: a randomized controlled proof-of-concept study

(2009) R. CORINALDESI et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Increased Proteasome-Mediated Degradation of Occludin in Irritable Bowel Syndrome

(2009) Moïse Coëffier et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Elevated Human β-Defensin-2 Levels Indicate an Activation of the Innate Immune System in Patients With Irritable Bowel Syndrome

(2009) Jost Langhorst et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Modulation of Intestinal Barrier Properties by Probiotics: Role in Reversing Colitis

(2009) Silvia C. Resta-Lenert et al.   Annals of the New York Academy of Sciences

Tight Junctions, Intestinal Permeability, and Autoimmunity

(2009) Jeroen Visser et al.   Annals of the New York Academy of Sciences

Barrier Effects of Nutritional Factors

(2009) Maren Amasheh et al.   Annals of the New York Academy of Sciences

MicroRNA-29a regulates intestinal membrane permeability in patients with irritable bowel syndrome

(2009) Q. Zhou et al.   GUT

Expression of catalytic proteasome subunits in the gut of patients with Crohn’s disease

(2009) Alexander Visekruna et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Analysis of Unstirred Water Layer in In Vitro Permeability Experiments

(2009) Timo Korjamo et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Common variants at five new loci associated with early-onset inflammatory bowel disease

(2009) Marcin Imielinski et al.   NATURE GENETICS

Intestinal membrane permeability and hypersensitivity in the irritable bowel syndrome

(2009) QiQi Zhou et al.   PAIN

Probiotics promote gut health through stimulation of epithelial innate immunity

(2009) C. Pagnini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The bacterial signal indole increases epithelial-cell tight-junction resistance and attenuates indicators of inflammation

(2009) T. Bansal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical trial: effect of active lactic acid bacteria on mucosal barrier function in patients with diarrhoea-predominant irritable bowel syndrome

(2008) J. ZENG et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

MicroRNAs Are Differentially Expressed in Ulcerative Colitis and Alter Expression of Macrophage Inflammatory Peptide-2α

(2008) Feng Wu et al.   GASTROENTEROLOGY

Targeted Epithelial Tight Junction Dysfunction Causes Immune Activation and Contributes to Development of Experimental Colitis

(2008) Liping Su et al.   GASTROENTEROLOGY

Impaired intestinal barrier integrity in the colon of patients with irritable bowel syndrome: involvement of soluble mediators

(2008) T Piche et al.   GUT

Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse

(2008) M C Arrieta et al.   GUT

First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor-type 3E gene with diarrhea predominant irritable bowel syndrome

(2008) Johannes Kapeller et al.   HUMAN MOLECULAR GENETICS

Increased Gastrointestinal Permeability and Gut Inflammation in Children with Functional Abdominal Pain and Irritable Bowel Syndrome

(2008) Robert J. Shulman et al.   JOURNAL OF PEDIATRICS

Protease-activated receptor 2 and gut permeability: a review

(2008) l. bueno et al.   NEUROGASTROENTEROLOGY AND MOTILITY