Chondro-Protective Effects of Shikimic Acid on Osteoarthritis via Restoring Impaired Autophagy and Suppressing the MAPK/NF-κB Signaling Pathway

The Role of Inflammation in the Pathogenesis of Osteoarthritis

(2020) Yoke Yue Chow et al.   MEDIATORS OF INFLAMMATION

Recombinant human irisin regulated collagen II, matrix metalloproteinase‑13 and the Wnt/β‑catenin and NF‑κB signaling pathways in interleukin‑1β‑induced human SW1353 cells

(2020) Xiaojun Li et al.   Experimental and Therapeutic Medicine

Melatonin activates autophagy via the NF-κB signaling pathway to prevent extracellular matrix degeneration in intervertebral disc

(2020) Fan Chen et al.   OSTEOARTHRITIS AND CARTILAGE

Potential diagnostic value of a type X collagen neo-epitope biomarker for knee osteoarthritis

(2019) Yi He et al.   OSTEOARTHRITIS AND CARTILAGE

Kinsenoside attenuates osteoarthritis by repolarizing macrophages through inactivating NF-κB/MAPK signaling and protecting chondrocytes

(2019) Feng Zhou et al.   Acta Pharmaceutica Sinica B

Berberine and musculoskeletal disorders: The therapeutic potential and underlying molecular mechanisms

(2019) Sok Kuan Wong et al.   PHYTOMEDICINE

How long does a knee replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of follow-up

(2019) Jonathan T Evans et al.   LANCET

Exploration of CRISPR/Cas9-based gene editing as therapy for osteoarthritis

(2019) Lan Zhao et al.   ANNALS OF THE RHEUMATIC DISEASES

Salicin inhibits AGE-induced degradation of type II collagen and aggrecan in human SW1353 chondrocytes: therapeutic potential in osteoarthritis

(2019) Feng Gao et al.   Artificial Cells Nanomedicine and Biotechnology

The Role of Autophagy in Chondrocyte Metabolism and Osteoarthritis: A Comprehensive Research Review

(2019) Pan Luo et al.   Biomed Research International

NF-B Signaling Pathways in Osteoarthritic Cartilage Destruction

(2019) Choi et al.   Cells

Safranin O without fast green is the best staining method for testing the degradation of macromolecules in a cartilage extracellular matrix for the determination of the postmortem interval

(2019) Armin Alibegović et al.   Forensic Science Medicine and Pathology

A Standardized Method of Applying Toluidine Blue Metachromatic Staining for Assessment of Chondrogenesis

(2018) Natasja Leth Bergholt et al.   Cartilage

Pravastatin alleviates interleukin 1β-induced cartilage degradation by restoring impaired autophagy associated with MAPK pathway inhibition

(2018) Zekai Mao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Negative Regulators of JAK/STAT Signaling in Rheumatoid Arthritis and Osteoarthritis

(2017) Charles Malemud   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2017) Simon I Hay et al.   LANCET

ADAMTS and ADAM metalloproteinases in osteoarthritis – looking beyond the ‘usual suspects’

(2017) C.-Y. Yang et al.   OSTEOARTHRITIS AND CARTILAGE

Trehalose ameliorates oxidative stress-mediated mitochondrial dysfunction and ER stress via selective autophagy stimulation and autophagic flux restoration in osteoarthritis development

(2017) Qian Tang et al.   Cell Death & Disease

Autophagy in osteoarthritis

(2016) Hyelin Jeon et al.   CONNECTIVE TISSUE RESEARCH

Shikimic acid inhibits LPS-induced cellular pro-inflammatory cytokines and attenuates mechanical hyperalgesia in mice

(2016) Thallita Kelly Rabelo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

An Autophagic Flux Probe that Releases an Internal Control

(2016) Takeshi Kaizuka et al.   MOLECULAR CELL

Osteoarthritis

(2016) Johanne Martel-Pelletier et al.   Nature Reviews Disease Primers

MAPK/JNK signaling: A potential autophagy regulation pathway

(2015) Yuan-Yuan Zhou et al.   BIOSCIENCE REPORTS

Cartilage-specific deletion of mTOR upregulates autophagy and protects mice from osteoarthritis

(2014) Yue Zhang et al.   ANNALS OF THE RHEUMATIC DISEASES

Preface

(2014) David J. Hunter   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

OARSI guidelines for the non-surgical management of knee osteoarthritis

(2014) T.E. McAlindon et al.   OSTEOARTHRITIS AND CARTILAGE

Transcriptional Induction of ADAMTS5 Protein by Nuclear Factor-κB (NF-κB) Family Member RelA/p65 in Chondrocytes during Osteoarthritis Development

(2013) Hiroshi Kobayashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Production of shikimic acid

(2012) Saptarshi Ghosh et al.   BIOTECHNOLOGY ADVANCES

A Short Overview on the Medicinal Chemistry of (—)-Shikimic Acid

(2012) Amalia M. Estevez et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Autophagy modulates osteoarthritis-related gene expression in human chondrocytes

(2011) Hiroshi Sasaki et al.   ARTHRITIS AND RHEUMATISM

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Illicium verum: A review on its botany, traditional use, chemistry and pharmacology

(2011) Guo-Wei Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis

(2010) Beatriz Caramés et al.   ARTHRITIS AND RHEUMATISM

The regulation of autophagy - unanswered questions

(2010) Y. Chen et al.   JOURNAL OF CELL SCIENCE

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the rat

(2010) N. Gerwin et al.   OSTEOARTHRITIS AND CARTILAGE

MAPKs are essential upstream signaling pathways in proteolytic cartilage degradation – divergence in pathways leading to aggrecanase and MMP-mediated articular cartilage degradation

(2009) B.-C. Sondergaard et al.   OSTEOARTHRITIS AND CARTILAGE

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

p38/NF‐kB‐dependent expression of COX‐2 during differentiation and inflammatory response of chondrocytes

(2008) Valentina Ulivi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

IL-1 and iNOS gene expression and NO synthesis in the superior region of meniscal explants are dependent on the magnitude of compressive strains

(2008) T. Gupta et al.   OSTEOARTHRITIS AND CARTILAGE

Stimulus (polyphenol, IFN-γ, LPS)-dependent nitric oxide production and antileishmanial effects in RAW 264.7 macrophages

(2008) Herbert Kolodziej et al.   PHYTOCHEMISTRY

Differential effects of tumor necrosis factor-α and interleukin-1β on cell death in human articular chondrocytes

(2007) B. Caramés et al.   OSTEOARTHRITIS AND CARTILAGE