- Home
- Publications
- Publication Search
- Publication Details
Title
The Role of Inflammation in the Pathogenesis of Osteoarthritis
Authors
Keywords
-
Journal
MEDIATORS OF INFLAMMATION
Volume 2020, Issue -, Pages 1-19
Publisher
Hindawi Limited
Online
2020-03-04
DOI
10.1155/2020/8293921
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Knockdown of FOXM1 attenuates inflammatory response in human osteoarthritis chondrocytes
- (2019) Run-ming Zeng et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- MiR-149 suppresses the inflammatory response of chondrocytes in osteoarthritis by down-regulating the activation of TAK1/NF-κB
- (2018) Qiaojie Chen et al. BIOMEDICINE & PHARMACOTHERAPY
- Inflammatory pattern of the infrapatellar fat pad in dogs with canine cruciate ligament disease
- (2018) Manuel R. Schmidli et al. BMC Veterinary Research
- Conditioned media from human osteoarthritic synovium induces inflammation in a synoviocyte cell line
- (2018) Elisa Belluzzi et al. CONNECTIVE TISSUE RESEARCH
- Ghrelin protects against osteoarthritis through interplay with Akt and NF-κB signaling pathways
- (2018) Ruize Qu et al. FASEB JOURNAL
- Th1/Th17/Th22 immune response and their association with joint pain, imagenological bone loss, RANKL expression and osteoclast activity in temporomandibular joint osteoarthritis: A preliminary report
- (2018) G. Monasterio et al. JOURNAL OF ORAL REHABILITATION
- Depletion of aquaporin 1 decreased ADAMTS‑4 expression in human chondrocytes
- (2018) Masahiko Haneda et al. Molecular Medicine Reports
- TSG-6 – a double-edged sword for osteoarthritis (OA)
- (2018) C.-H. Chou et al. OSTEOARTHRITIS AND CARTILAGE
- Altered Wnt and NF-κB Signaling in Facet Joint Osteoarthritis: Insights from RNA Deep Sequencing
- (2018) Chu Chen et al. TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE
- Inhibition of miR-126 protects chondrocytes from IL-1β induced inflammation via upregulation of Bcl-2
- (2018) C. D. Yu et al. Bone & Joint Research
- miR-373 regulates inflammatory cytokine-mediated chondrocyte proliferation in osteoarthritis by targeting the P2X7 receptor
- (2018) Wei Zhang et al. FEBS Open Bio
- Neutrophil: A Cell with Many Roles in Inflammation or Several Cell Types?
- (2018) Carlos Rosales Frontiers in Physiology
- PKR activation causes inflammation and MMP-13 secretion in human degenerated articular chondrocytes
- (2018) Ching-Hou Ma et al. Redox Biology
- TNF‑α increases the expression of inflammatory factors in synovial fibroblasts by inhibiting the PI3K/AKT pathway in a rat model of monosodium iodoacetate‑induced osteoarthritis
- (2018) Hongxi Li et al. Experimental and Therapeutic Medicine
- MicroRNA‑93 inhibits chondrocyte apoptosis and inflammation in osteoarthritis by targeting the TLR4/NF‑κB signaling pathway
- (2018) Yanjie Ding et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Upregulation of stanniocalcin-1 inhibits the development of osteoarthritis by inhibiting survival and inflammation of fibroblast-like synovial cells
- (2018) Ying Wu et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Inflammatory molecules produced by meniscus and synovium in early and end-stage osteoarthritis: a coculture study
- (2018) Marta Favero et al. JOURNAL OF CELLULAR PHYSIOLOGY
- CCR2 upregulated on peripheral T cells in osteoarthritis but not in bone marrow
- (2018) Kurt Arkestål et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- Knockdown of PRMT1 suppresses IL-1β-induced cartilage degradation and inflammatory responses in human chondrocytes through Gli1-mediated Hedgehog signaling pathway
- (2017) Lei Xia et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Dual specificity phosphatase 1 has a protective role in osteoarthritis fibroblast-like synoviocytes via inhibition of the MAPK signaling pathway
- (2017) Hua-Zhi Peng et al. Molecular Medicine Reports
- Increased frequency of peripheral blood follicular helper T cells and elevated serum IL-21 levels in patients with knee osteoarthritis
- (2017) Yuxing Shan et al. Molecular Medicine Reports
- The potential of P2X7 receptors as a therapeutic target, including inflammation and tumour progression
- (2017) Geoffrey Burnstock et al. Purinergic Signalling
- Platelets Contribute to the Accumulation of Matrix Metalloproteinase Type 2 in Synovial Fluid in Osteoarthritis
- (2017) Filippo Luccioli et al. THROMBOSIS AND HAEMOSTASIS
- SOCS1 Regulates Apoptosis and Inflammation by Inhibiting IL-4 Signaling in IL-1β-Stimulated Human Osteoarthritic Chondrocytes
- (2017) Qiang He et al. Biomed Research International
- The P2X7 Receptor-Interleukin-1 Liaison
- (2017) Anna Lisa Giuliani et al. Frontiers in Pharmacology
- T Cells in Osteoarthritis: Alterations and Beyond
- (2017) Yu-sheng Li et al. Frontiers in Immunology
- Presence of IL-17 in synovial fluid identifies a potential inflammatory osteoarthritic phenotype
- (2017) Sarah J. B. Snelling et al. PLoS One
- IL-37 is associated with osteoarthritis disease activity and suppresses proinflammatory cytokines production in synovial cells
- (2017) Liping Ding et al. Scientific Reports
- CCL2/CCR2, but not CCL5/CCR5, mediates monocyte recruitment, inflammation and cartilage destruction in osteoarthritis
- (2016) Harini Raghu et al. ANNALS OF THE RHEUMATIC DISEASES
- α-MSH modulates cell adhesion and inflammatory responses of synovial fibroblasts from osteoarthritis patients
- (2016) Markus Böhm et al. BIOCHEMICAL PHARMACOLOGY
- Plasma and synovial fluid inflammatory cytokine profiles in primary knee osteoarthritis
- (2016) Thomas Mabey et al. BIOMARKERS
- MiR-502-5p inhibits IL-1β-induced chondrocyte injury by targeting TRAF2
- (2016) Guoliang Zhang et al. CELLULAR IMMUNOLOGY
- Upregulated expression of CCR3 in osteoarthritis and CCR3 mediated activation of fibroblast-like synoviocytes
- (2016) Xin Chang et al. CYTOKINE
- Overexpression of HMGB1 A-box reduced IL-1β-induced MMP expression and the production of inflammatory mediators in human chondrocytes
- (2016) Yahui Fu et al. EXPERIMENTAL CELL RESEARCH
- Blocking of the P2X7 receptor inhibits the activation of the MMP-13 and NF-κB pathways in the cartilage tissue of rats with osteoarthritis
- (2016) Hongbo Hu et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- PPAR-α Agonist WY-14643 Inhibits LPS-Induced Inflammation in Synovial Fibroblasts via NF-kB Pathway
- (2016) Degang Huang et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Cartilage inflammation and degeneration is enhanced by pro-inflammatory (M1) macrophages in vitro , but not inhibited directly by anti-inflammatory (M2) macrophages
- (2016) L. Utomo et al. OSTEOARTHRITIS AND CARTILAGE
- IL37 dampens the IL1β-induced catabolic status of human OA chondrocytes
- (2016) Ellen W. van Geffen et al. RHEUMATOLOGY
- Poly(ADP-ribose) polymerase 1 inhibition prevents interleukin-1β-induced inflammation in human osteoarthritic chondrocytes
- (2015) Yujie Sun et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- α-Melanocyte-stimulating-hormone (α-MSH) modulates human chondrocyte activation induced by proinflammatory cytokines
- (2015) Franco Capsoni et al. BMC MUSCULOSKELETAL DISORDERS
- KPNA2 interacts with P65 to modulate catabolic events in osteoarthritis
- (2015) Ran Tao et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- High MMP-1, MMP-2, and MMP-9 protein levels in osteoarthritis
- (2015) G.Q. Zeng et al. GENETICS AND MOLECULAR RESEARCH
- The chemokine CCL20 induces proinflammatory and matrix degradative responses in cartilage
- (2015) Nada Alaaeddine et al. INFLAMMATION RESEARCH
- Sam68 Promotes NF-κB Activation and Apoptosis Signaling in Articular Chondrocytes during Osteoarthritis
- (2015) Libin Xu et al. INFLAMMATION RESEARCH
- Cadherin-11 involves in synovitis and increases the migratory and invasive capacity of fibroblast-like synoviocytes of osteoarthritis
- (2015) Xiaoquan Ding et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Advanced glycation end-products induced VEGF production and inflammatory responses in human synoviocytes via RAGE-NF-κB pathway activation
- (2015) Ying-Ju Chen et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- TGF-β is a potent inducer of Nerve Growth Factor in articular cartilage via the ALK5-Smad2/3 pathway. Potential role in OA related pain?
- (2015) E.N. Blaney Davidson et al. OSTEOARTHRITIS AND CARTILAGE
- Differential expression of interleukin-17 and interleukin-22 in inflamed and non-inflamed synovium from osteoarthritis patients
- (2015) C. Deligne et al. OSTEOARTHRITIS AND CARTILAGE
- Call for standardized definitions of osteoarthritis and risk stratification for clinical trials and clinical use
- (2015) V.B. Kraus et al. OSTEOARTHRITIS AND CARTILAGE
- The Role of PPARγ in Advanced Glycation End Products-Induced Inflammatory Response in Human Chondrocytes
- (2015) Chi Ma et al. PLoS One
- The involvement of follistatin-like protein 1 in osteoarthritis by elevating NF-κB-mediated inflammatory cytokines and enhancing fibroblast like synoviocyte proliferation
- (2015) Su Ni et al. ARTHRITIS RESEARCH & THERAPY
- Soluble Macrophage Biomarkers Indicate Inflammatory Phenotypes in Patients With Knee Osteoarthritis
- (2015) Hikmat N. Daghestani et al. Arthritis & Rheumatology
- The Role of Inflammatory and Anti-Inflammatory Cytokines in the Pathogenesis of Osteoarthritis
- (2014) Piotr Wojdasiewicz et al. MEDIATORS OF INFLAMMATION
- Effect of hydrogen sulfide sources on inflammation and catabolic markers on interleukin 1β-stimulated human articular chondrocytes
- (2014) E.F. Burguera et al. OSTEOARTHRITIS AND CARTILAGE
- Osteoarthritis Year in Review 2014: genetics and genomics
- (2014) A. Tsezou OSTEOARTHRITIS AND CARTILAGE
- Human Osteoarthritic Cartilage Shows Reduced In Vivo Expression of IL-4, a Chondroprotective Cytokine that Differentially Modulates IL-1β-Stimulated Production of Chemokines and Matrix-Degrading Enzymes In Vitro
- (2014) Elisa Assirelli et al. PLoS One
- The Complexity of Human Walking: A Knee Osteoarthritis Study
- (2014) Margarita Kotti et al. PLoS One
- Neutrophil-Derived Cytokines: Facts Beyond Expression
- (2014) Cristina Tecchio et al. Frontiers in Immunology
- Epidemiology and burden of osteoarthritis
- (2013) A. Litwic et al. BRITISH MEDICAL BULLETIN
- IL-22/IL-22R1 axis and S100A8/A9 alarmins in human osteoarthritic and rheumatoid arthritis synovial fibroblasts
- (2013) Mar Carrión et al. RHEUMATOLOGY
- An emerging player in knee osteoarthritis: the infrapatellar fat pad
- (2013) Andreea Ioan-Facsinay et al. ARTHRITIS RESEARCH & THERAPY
- Role of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretations
- (2013) Jeremy Sokolove et al. Therapeutic Advances in Musculoskeletal Disease
- Cytokine production by infrapatellar fat pad can be stimulated by interleukin 1β and inhibited by peroxisome proliferator activated receptor α agonist
- (2012) Stefan Clockaerts et al. ANNALS OF THE RHEUMATIC DISEASES
- The role of synovitis in osteoarthritis pathogenesis
- (2012) Carla R. Scanzello et al. BONE
- Interleukin-21 promotes osteoclastogenesis in humans with rheumatoid arthritis and in mice with collagen-induced arthritis
- (2011) Seung-Ki Kwok et al. ARTHRITIS AND RHEUMATISM
- The pro- and anti-inflammatory properties of the cytokine interleukin-6
- (2011) Jürgen Scheller et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: Outside-in signaling and relationship to tumor progression
- (2011) Brigitte Bauvois BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Inflammation in osteoarthritis
- (2011) Mary B. Goldring et al. CURRENT OPINION IN RHEUMATOLOGY
- Articular cartilage and subchondral bone in the pathogenesis of osteoarthritis
- (2010) Mary B. Goldring et al. Annals of the New York Academy of Sciences
- Why is osteoarthritis an age-related disease?
- (2010) A. Shane Anderson et al. BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY
- NF-κB Signaling: Multiple Angles to Target OA
- (2010) Kenneth B. Marcu et al. CURRENT DRUG TARGETS
- The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis
- (2010) Jérémie Sellam et al. Nature Reviews Rheumatology
- MicroRNAs: Target Recognition and Regulatory Functions
- (2009) David P. Bartel CELL
- WDR34 is a novel TAK1-associated suppressor of the IL-1R/TLR3/TLR4-induced NF-κB activation pathway
- (2009) Dong Gao et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Critical roles of the TGF-β type I receptor ALK5 in perichondrial formation and function, cartilage integrity, and osteoblast differentiation during growth plate development
- (2009) Tomoya Matsunobu et al. DEVELOPMENTAL BIOLOGY
- IL-1β Augments TNF-α–Mediated Inflammatory Responses from Lung Epithelial Cells
- (2009) Sara Saperstein et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Mitogen-activated protein kinases as therapeutic targets in osteoarthritis
- (2008) Richard F Loeser et al. CURRENT OPINION IN RHEUMATOLOGY
- The Interleukin 1β Pathway in the Pathogenesis of Osteoarthritis
- (2008) Massoud Daheshia et al. JOURNAL OF RHEUMATOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now