Differential effects of SUMO1 and SUMO2 on circadian protein PER2 stability and function

NAD+ Controls Circadian Reprogramming through PER2 Nuclear Translocation to Counter Aging

(2020) Daniel C. Levine et al.   MOLECULAR CELL

Mutation of a PER2 phosphodegron perturbs the circadian phosphoswitch

(2020) Shusaku Masuda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TwoCk1δtranscripts regulated by m6A methylation code for two antagonistic kinases in the control of the circadian clock

(2018) Jean-Michel Fustin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CK1δ/ε protein kinase primes the PER2 circadian phosphoswitch

(2018) Rajesh Narasimamurthy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pro-inflammatory cytokines IL-6 and CCL2 suppress expression of circadian gene Period2 in mammary epithelial cells

(2018) Chan-Wei Yu et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Distinct control of PERIOD2 degradation and circadian rhythms by the oncoprotein and ubiquitin ligase MDM2

(2018) JingJing Liu et al.   Science Signaling

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation

(2017) Ivo A Hendriks et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation

(2017) Ivo A Hendriks et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Circadian Rhythm Disruption Promotes Lung Tumorigenesis

(2016) Thales Papagiannakopoulos et al.   Cell Metabolism

The intricate dance of post-translational modifications in the rhythm of life

(2016) Arisa Hirano et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mammalian Period represses and de-represses transcription by displacing CLOCK–BMAL1 from promoters in a Cryptochrome-dependent manner

(2016) Yi-Ying Chiou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The intricate dance of post-translational modifications in the rhythm of life

(2016) Arisa Hirano et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Period2 Phosphoswitch Regulates and Temperature Compensates Circadian Period

(2015) Min Zhou et al.   MOLECULAR CELL

SCFβ-TRCP promotes cell growth by targeting PR-Set7/Set8 for degradation

(2015) Zhiwei Wang et al.   Nature Communications

GPS-SUMO: a tool for the prediction of sumoylation sites and SUMO-interaction motifs

(2014) Qi Zhao et al.   NUCLEIC ACIDS RESEARCH

SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination

(2014) Hong-Bin Luo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli

(2014) F. Impens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sumoylation differentially regulates Sp1 to control cell differentiation

(2014) L. Gong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A central role for ubiquitination within a circadian clock protein modification code

(2014) Katarina Stojkovic et al.   Frontiers in Molecular Neuroscience

Glucose Sensor O-GlcNAcylation Coordinates with Phosphorylation to Regulate Circadian Clock

(2013) Krista Kaasik et al.   Cell Metabolism

Detecting endogenous SUMO targets in mammalian cells and tissues

(2013) Janina Becker et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Loss of corepressor PER2 under hypoxia up-regulates OCT1-mediated EMT gene expression and enhances tumor malignancy

(2013) W. W. Hwang-Verslues et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular architecture of the mammalian circadian clock

(2013) Carrie L. Partch et al.   TRENDS IN CELL BIOLOGY

Rev-erb  and Rev-erb  coordinately protect the circadian clock and normal metabolic function

(2012) A. Bugge et al.   GENES & DEVELOPMENT

Kinases and phosphatases in the mammalian circadian clock

(2011) Silke Reischl et al.   FEBS LETTERS

Casein Kinase 1-dependent Phosphorylation of Familial Advanced Sleep Phase Syndrome-associated Residues Controls PERIOD 2 Stability

(2011) Naval P. Shanware et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1

(2011) H.-m. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors

(2010) I. Schmutz et al.   GENES & DEVELOPMENT

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

(2010) Jaclyn R. Gareau et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

High-Throughput Chemical Screen Identifies a Novel Potent Modulator of Cellular Circadian Rhythms and Reveals CKIα as a Clock Regulatory Kinase

(2010) Tsuyoshi Hirota et al.   PLOS BIOLOGY

Involvement of the Protein Kinase CK2 in the Regulation of Mammalian Circadian Rhythms

(2009) Y. Tsuchiya et al.   Science Signaling

Harmonics of Circadian Gene Transcription in Mammals

(2009) Michael E. Hughes et al.   PLoS Genetics

A novel method for high accuracy sumoylation site prediction from protein sequences

(2008) Jialin Xu et al.   BMC BIOINFORMATICS

SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation

(2008) Gad Asher et al.   CELL

Loss of SUMO1 in mice affects RanGAP1 localization and formation of PML nuclear bodies, but is not lethal as it can be compensated by SUMO2 or SUMO3

(2008) E. Evdokimov et al.   JOURNAL OF CELL SCIENCE

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

(2008) Michael H. Tatham et al.   NATURE CELL BIOLOGY

Redundant Function of REV-ERBα and β and Non-Essential Role for Bmal1 Cycling in Transcriptional Regulation of Intracellular Circadian Rhythms

(2008) Andrew C. Liu et al.   PLoS Genetics