Structures of the SARS ‐CoV‐2 nucleocapsid and their perspectives for drug design

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

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Structure-based stabilization of non-native protein-protein interactions of coronavirus nucleocapsid proteins in antiviral drug design

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Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding

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A distinct name is needed for the new coronavirus

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A novel coronavirus outbreak of global health concern

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A new coronavirus associated with human respiratory disease in China

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A pneumonia outbreak associated with a new coronavirus of probable bat origin

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A Novel Coronavirus from Patients with Pneumonia in China, 2019

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Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia

(2020) Qun Li et al.   NEW ENGLAND JOURNAL OF MEDICINE

The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2

(2020)   Nature Microbiology

Identification of Human Single-Domain Antibodies against SARS-CoV-2

(2020) Yanling Wu et al.   Cell Host & Microbe

Antibody Detection and Dynamic Characteristics in Patients with COVID-19

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A Novel Bat Coronavirus Closely Related to SARS-CoV-2 Contains Natural Insertions at the S1/S2 Cleavage Site of the Spike Protein

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Detection of SARS-CoV-2-Specific Humoral and Cellular Immunity in COVID-19 Convalescent Individuals

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Detection of Nucleocapsid Antibody to SARS-CoV-2 is More Sensitive than Antibody to Spike Protein in COVID-19 Patients

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A human neutralizing antibody targets the receptor binding site of SARS-CoV-2

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Viral and host factors related to the clinical outcome of COVID-19

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Remdesivir for the Treatment of Covid-19 — Preliminary Report

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A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19

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A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2

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SARS-CoV-2-encoded nucleocapsid protein acts as a viral suppressor of RNA interference in cells

(2020) Jingfang Mu et al.   Science China-Life Sciences

Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites

(2020) Sisi Kang et al.   Acta Pharmaceutica Sinica B

The COVID-19 Vaccine Race: Challenges and Opportunities in Vaccine Formulation

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Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2

(2020) Markus Hoffmann et al.   NATURE

Hydroxychloroquine use against SARS-CoV-2 infection in non-human primates

(2020) Pauline Maisonnasse et al.   NATURE

Hydroxychloroquine with or without Azithromycin in Mild-to-Moderate Covid-19

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Architecture and self‐assembly of the SARS‐CoV ‐2 nucleocapsid protein

(2020) Qiaozhen Ye et al.   PROTEIN SCIENCE

Evaluation of three fully-automated SARS-CoV-2 antibody assays

(2020) Sebastian Hörber et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Structure and oligomerization state of the C-terminal region of the Middle East respiratory syndrome coronavirus nucleoprotein

(2019) Thi Hong Van Nguyen et al.   Acta Crystallographica Section D-Structural Biology

Nucleocapsid protein recruitment to replication-transcription complexes plays a crucial role in coronaviral life cycle

(2019) Yingying Cong et al.   JOURNAL OF VIROLOGY

Crystal Structure of African Swine Fever Virus dUTPase Reveals a Potential Drug Target

(2019) Changyao Li et al.   mBio

Structural Characterization of Human Coronavirus NL63 N Protein

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Crystal structure of the C-terminal fragment of NS1 protein from yellow fever virus

(2017) Haiyuan Wang et al.   Science China-Life Sciences

Coronavirus nucleocapsid proteins assemble constitutively in high molecular oligomers

(2017) Yingying Cong et al.   Scientific Reports

Electron microscopy studies of the coronavirus ribonucleoprotein complex

(2017) Miao Gui et al.   Protein & Cell

Structure-based virtual screening and experimental validation of the discovery of inhibitors targeted towards the human coronavirus nucleocapsid protein

(2016) Chung-ke Chang et al.   Molecular BioSystems

ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules

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Structural characterization of the N-terminal part of the MERS-CoV nucleocapsid by X-ray diffraction and small-angle X-ray scattering

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The SARS coronavirus nucleocapsid protein – Forms and functions

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Structural Basis for the Identification of the N-Terminal Domain of Coronavirus Nucleocapsid Protein as an Antiviral Target

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Overview of theCCP4 suite and current developments

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

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SARS-CoV nucleocapsid protein antagonizes IFN-β response by targeting initial step of IFN-β induction pathway, and its C-terminal region is critical for the antagonism

(2010) Xiaolu Lu et al.   VIRUS GENES

Coronavirus Nucleocapsid Protein Facilitates Template Switching and Is Required for Efficient Transcription

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Cryo-electron tomography of mouse hepatitis virus: Insights into the structure of the coronavirion

(2009) M. Barcena et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of the arginine/serine dipeptide-rich motif of the severe acute respiratory syndrome coronavirus nucleocapsid protein modulates its multimerization, translation inhibitory activity and cellular localization

(2008) Tsui-Yi Peng et al.   FEBS Journal