SNX19 restricts endolysosome motility through contacts with the endoplasmic reticulum

Variations and expression features of CYP2D6 contribute to schizophrenia risk

(2020) Liang Ma et al.   MOLECULAR PSYCHIATRY

Lipid rafts are required for effective renal D 1 dopamine receptor function

(2020) Andrew C. Tiu et al.   FASEB JOURNAL

ARL8 Relieves SKIP Autoinhibition to Enable Coupling of Lysosomes to Kinesin-1

(2020) Tal Keren-Kaplan et al.   CURRENT BIOLOGY

Schizophrenia risk variants influence multiple classes of transcripts of sorting nexin 19 (SNX19)

(2019) Liang Ma et al.   MOLECULAR PSYCHIATRY

Coming together to define membrane contact sites

(2019) Luca Scorrano et al.   Nature Communications

Cerebellar ataxia disease–associated Snx14 promotes lipid droplet growth at ER–droplet contacts

(2019) Sanchari Datta et al.   JOURNAL OF CELL BIOLOGY

Mdm1 maintains endoplasmic reticulum homeostasis by spatially regulating lipid droplet biogenesis

(2019) Hanaa Hariri et al.   JOURNAL OF CELL BIOLOGY

Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities

(2019) Mintu Chandra et al.   Nature Communications

Drosophila Snazarus Regulates a Lipid Droplet Population at Plasma Membrane-Droplet Contacts in Adipocytes

(2019) Rupali Ugrankar et al.   DEVELOPMENTAL CELL

Lysosomes as dynamic regulators of cell and organismal homeostasis

(2019) Andrea Ballabio et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Integrating genome-wide association study and methylation functional annotation data identified candidate genes and pathways for schizophrenia

(2019) Xin Qi et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Lipid-gated monovalent ion fluxes regulate endocytic traffic and support immune surveillance

(2019) Spencer A. Freeman et al.   SCIENCE

SNX14 mutations affect endoplasmic reticulum-associated neutral lipid metabolism in autosomal recessive spinocerebellar ataxia 20

(2018) Dale Bryant et al.   HUMAN MOLECULAR GENETICS

Single organelle dynamics linked to 3D structure by correlative live-cell imaging and 3D electron microscopy

(2018) Job Fermie et al.   TRAFFIC

VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites

(2018) Nikit Kumar et al.   JOURNAL OF CELL BIOLOGY

Here, there, and everywhere: The importance of ER membrane contact sites

(2018) Haoxi Wu et al.   SCIENCE

Visualizing Intracellular Organelle and Cytoskeletal Interactions at Nanoscale Resolution on Millisecond Timescales

(2018) Yuting Guo et al.   CELL

The lysosome as a cellular centre for signalling, metabolism and quality control

(2018) Rosalie E. Lawrence et al.   NATURE CELL BIOLOGY

Noncanonical autophagy at ER exit sites regulates procollagen turnover

(2018) Shakib Omari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci

(2017) John F Fullard et al.   HUMAN MOLECULAR GENETICS

Endosome-ER Contacts Control Actin Nucleation and Retromer Function through VAP-Dependent Regulation of PI4P

(2016) Rui Dong et al.   CELL

An ER-Associated Pathway Defines Endosomal Architecture for Controlled Cargo Transport

(2016) Marlieke L.M. Jongsma et al.   CELL

Phosphatidylinositol 3‐phosphates—at the interface between cell signalling and membrane traffic

(2016) Andrea L Marat et al.   EMBO JOURNAL

Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets

(2016) Zhihong Zhu et al.   NATURE GENETICS

Mdm1/Snx13 is a novel ER–endolysosomal interorganelle tethering protein

(2015) W. Mike Henne et al.   JOURNAL OF CELL BIOLOGY

Repeated ER–endosome contacts promote endosome translocation and neurite outgrowth

(2015) Camilla Raiborg et al.   NATURE

Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction

(2015) Naiara Akizu et al.   NATURE GENETICS

Mutations in SNX14 Cause a Distinctive Autosomal-Recessive Cerebellar Ataxia and Intellectual Disability Syndrome

(2014) Anna C. Thomas et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling

(2014) Caroline Mas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy

(2014) Baptiste Ronan et al.   Nature Chemical Biology

Genome-Wide Associations between Genetic and Epigenetic Variation Influence mRNA Expression and Insulin Secretion in Human Pancreatic Islets

(2014) Anders H. Olsson et al.   PLoS Genetics

PIKfyve, a Class III PI Kinase, Is the Target of the Small Molecular IL-12/IL-23 Inhibitor Apilimod and a Player in Toll-like Receptor Signaling

(2013) Xinming Cai et al.   CHEMISTRY & BIOLOGY

Insights into the PX (phox-homology) domain and SNX (sorting nexin) protein families: structures, functions and roles in disease

(2011) Rohan D. Teasdale et al.   BIOCHEMICAL JOURNAL

Sorting nexin 19 regulates the number of dense core vesicles in pancreatic β-cells

(2011) Shin-ichi Harashima et al.   Journal of Diabetes Investigation

ER sliding dynamics and ER–mitochondrial contacts occur on acetylated microtubules

(2010) Jonathan R. Friedman et al.   JOURNAL OF CELL BIOLOGY

Screening of chondrogenic factors with a real-time fluorescence-monitoring cell line ATDC5-C2ER: Identification of sorting nexin 19 as a novel factor

(2009) Akinori Kan et al.   ARTHRITIS AND RHEUMATISM

Expression and Function of IA-2 Family Proteins, Unique Neuroendocrine-specific Protein-tyrosine Phosphatases

(2009) Seiji TORII   ENDOCRINE JOURNAL

Promotion of Neurite Extension by Protrudin Requires Its Interaction with Vesicle-associated Membrane Protein-associated Protein

(2009) Shotaro Saita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7–RILP–p150Gluedand late endosome positioning

(2009) Nuno Rocha et al.   JOURNAL OF CELL BIOLOGY

HELIQUEST: a web server to screen sequences with specific  -helical properties

(2008) R. Gautier et al.   BIOINFORMATICS

PXA Domain-Containing Protein Pxa1 Is Required for Normal Vacuole Function and Morphology inSchizosaccharomyces pombe

(2008) Akira HOSOMI et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Robust single-particle tracking in live-cell time-lapse sequences

(2008) Khuloud Jaqaman et al.   NATURE METHODS