Cerebellar ataxia disease–associated Snx14 promotes lipid droplet growth at ER–droplet contacts

Mdm1 maintains endoplasmic reticulum homeostasis by spatially regulating lipid droplet biogenesis

(2019) Hanaa Hariri et al.   JOURNAL OF CELL BIOLOGY

Mechanism and Determinants of Amphipathic Helix-Containing Protein Targeting to Lipid Droplets

(2018) Coline Prévost et al.   DEVELOPMENTAL CELL

SNX14 mutations affect endoplasmic reticulum-associated neutral lipid metabolism in autosomal recessive spinocerebellar ataxia 20

(2018) Dale Bryant et al.   HUMAN MOLECULAR GENETICS

Rab18 promotes lipid droplet (LD) growth by tethering the ER to LDs through SNARE and NRZ interactions

(2018) Dijin Xu et al.   JOURNAL OF CELL BIOLOGY

Human SEIPIN Binds Anionic Phospholipids

(2018) Renhong Yan et al.   DEVELOPMENTAL CELL

Cryo–electron microscopy structure of the lipid droplet–formation protein seipin

(2018) Xuewu Sui et al.   JOURNAL OF CELL BIOLOGY

Autosomal recessive spinocerebellar ataxia 20: Report of a new patient and review of literature

(2017) Anju Shukla et al.   European Journal of Medical Genetics

Pet10p is a yeast perilipin that stabilizes lipid droplets and promotes their assembly

(2017) Qiang Gao et al.   JOURNAL OF CELL BIOLOGY

Seipin regulates ER–lipid droplet contacts and cargo delivery

(2016) Veijo T Salo et al.   EMBO JOURNAL

SEIPIN Regulates Lipid Droplet Expansion and Adipocyte Development by Modulating the Activity of Glycerol-3-phosphate Acyltransferase

(2016) Martin Pagac et al.   Cell Reports

Seipin is required for converting nascent to mature lipid droplets

(2016) Huajin Wang et al.   eLife

Seipin performs dissectible functions in promoting lipid droplet biogenesis and regulating droplet morphology

(2015) Bethany R. Cartwright et al.   MOLECULAR BIOLOGY OF THE CELL

Mutations in SNX14 Cause a Distinctive Autosomal-Recessive Cerebellar Ataxia and Intellectual Disability Syndrome

(2014) Anna C. Thomas et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling

(2014) Caroline Mas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Directed evolution of APEX2 for electron microscopy and proximity labeling

(2014) Stephanie S Lam et al.   NATURE METHODS

Arf1/COPI machinery acts directly on lipid droplets and enables their connection to the ER for protein targeting

(2014) Florian Wilfling et al.   eLife

Triacylglycerol Synthesis Enzymes Mediate Lipid Droplet Growth by Relocalizing from the ER to Lipid Droplets

(2013) Florian Wilfling et al.   DEVELOPMENTAL CELL

Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains

(2013) Adam Kassan et al.   JOURNAL OF CELL BIOLOGY

The FATP1–DGAT2 complex facilitates lipid droplet expansion at the ER–lipid droplet interface

(2012) Ningyi Xu et al.   JOURNAL OF CELL BIOLOGY

Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy

(2012) Jeffrey D Martell et al.   NATURE BIOTECHNOLOGY

Isolating lipid droplets from multiple species

(2012) Yunfeng Ding et al.   Nature Protocols

A fluorescent assay to quantitatively measure in vitro acyl CoA:diacylglycerol acyltransferase activity

(2011) Pamela J. McFie et al.   JOURNAL OF LIPID RESEARCH

Not Just Fat: The Structure and Function of the Lipid Droplet

(2011) T. Fujimoto et al.   Cold Spring Harbor Perspectives in Biology

Lipid droplets at a glance

(2009) Y. Guo et al.   JOURNAL OF CELL SCIENCE

Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast

(2008) Weihua Fei et al.   JOURNAL OF CELL BIOLOGY