Polycomb-dependent histone H2A ubiquitination links developmental disorders with cancer

JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications

(2021) Vignesh Kasinath et al.   SCIENCE

Emerging multifaceted roles of BAP1 complexes in biological processes

(2021) Aileen Patricia Szczepanski et al.   Cell Death Discovery

Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy

(2021) Miles K. Huseyin et al.   Nature Communications

Ubiquitin‐dependent regulation of transcription in development and disease

(2021) Kevin G Mark et al.   EMBO REPORTS

BAP1 constrains pervasive H2AK119ub1 to control the transcriptional potential of the genome

(2021) Nadezda A. Fursova et al.   GENES & DEVELOPMENT

Rare deleterious de novo missense variants in RNF2/RING2 are associated with a neurodevelopmental disorder with unique clinical features

(2021) Xi Luo et al.   HUMAN MOLECULAR GENETICS

The Polycomb landscape in mouse development

(2021) Julien Richard Albert et al.   NATURE GENETICS

Distinct dynamics and functions of H2AK119ub1 and H3K27me3 in mouse preimplantation embryos

(2021) Zhiyuan Chen et al.   NATURE GENETICS

Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands

(2021) Daniel N. Weinberg et al.   NATURE GENETICS

BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation

(2021) Eric Conway et al.   MOLECULAR CELL

Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain

(2021) Shirish Shukla et al.   Nature Chemical Biology

PTC209, a Specific Inhibitor of BMI1, Promotes Cell Cycle Arrest and Apoptosis in Cervical Cancer Cell Lines

(2020) JUNAN LI et al.   ANTICANCER RESEARCH

A central role for canonical PRC1 in shaping the 3D nuclear landscape

(2020) Shelagh Boyle et al.   GENES & DEVELOPMENT

De novo mutations in FBRSL1 cause a novel recognizable malformation and intellectual disability syndrome

(2020) Roser Ufartes et al.   HUMAN GENETICS

RYBP/YAF2-PRC1 complexes and histone H1-dependent chromatin compaction mediate propagation of H2AK119ub1 during cell division

(2020) Jicheng Zhao et al.   NATURE CELL BIOLOGY

PR-DUB maintains expression of critical genes through FOXK1/2 and ASXL1/2/3-dependent recruitment to chromatin and H2AK119ub1 deubiquitination

(2020) Petros Kolovos et al.   GENOME RESEARCH

The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma

(2020) Matthew J. McBride et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ASXL3 bridges BRD4 to BAP1 complex and governs enhancer activity in small cell lung cancer

(2020) Aileen Patricia Szczepanski et al.   Genome Medicine

Insights into epigenetic patterns in mammalian early embryos

(2020) Ruimin Xu et al.   Protein & Cell

The genetic basis for PRC1 complex diversity emerged early in animal evolution

(2020) James M. Gahan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The emerging role of chromatin remodelers in neurodevelopmental disorders: a developmental perspective

(2020) Britt Mossink et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases

(2020) Wanqiu Li et al.   NATURE

Ancestry of the AUTS2 family–A novel group of polycomb-complex proteins involved in human neurological disease

(2020) Robert A. Sellers et al.   PLoS One

Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes

(2020) Haithem Barbour et al.   Nature Communications

Rubinstein-Taybi syndrome in a Saudi boy with distinct features and variants in both the CREBBP and EP300 genes: a case report

(2019) Mohammad M. Al-Qattan et al.   BMC Medical Genetics

Structural Basis for the Activation of the Deubiquitinase Calypso by the Polycomb Protein ASX

(2019) Inessa De et al.   STRUCTURE

BAP1 complex promotes transcription by opposing PRC1-mediated H2A ubiquitylation

(2019) Antoine Campagne et al.   Nature Communications

EED and EZH2 constitutive variants: A study to expand the Cohen-Gibson syndrome phenotype and contrast it with Weaver syndrome

(2019) Sara Griffiths et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Dangerous liaisons: interplay between SWI/SNF, NuRD, and Polycomb in chromatin regulation and cancer

(2019) Adrian P. Bracken et al.   GENES & DEVELOPMENT

Functional Landscape of PCGF Proteins Reveals Both RING1A/B-Dependent-and RING1A/B-Independent-Specific Activities

(2019) Andrea Scelfo et al.   MOLECULAR CELL

Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression

(2019) Nadezda A. Fursova et al.   MOLECULAR CELL

Molecular Mechanisms Directing PRC2 Recruitment and H3K27 Methylation

(2019) Anne Laugesen et al.   MOLECULAR CELL

Dissecting the role of H3K27 acetylation and methylation in PRC2 mediated control of cellular identity

(2019) Elisa Lavarone et al.   Nature Communications

De novo Mutations From Whole Exome Sequencing in Neurodevelopmental and Psychiatric Disorders: From Discovery to Application

(2019) Weidi Wang et al.   Frontiers in Genetics

Loss of PRC1 activity in different stem cell compartments activates a common transcriptional program with cell type–dependent outcomes

(2019) Silvia Pivetti et al.   Science Advances

The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression

(2019) Wenjing Su et al.   CANCER CELL

Chromatin folding and nuclear architecture: PRC1 function in 3D

(2019) Robert S Illingworth   CURRENT OPINION IN GENETICS & DEVELOPMENT

Phase separation of Polycomb-repressive complex 1 is governed by a charged disordered region of CBX2

(2019) Aaron J. Plys et al.   GENES & DEVELOPMENT

PRC2 functions in development and congenital disorders

(2019) Orla Deevy et al.   DEVELOPMENT

BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers

(2019) Jeffim N. Kuznetsov et al.   Science Advances

Optimization of Ligands Using Focused DNA-Encoded Libraries To Develop a Selective, Cell-Permeable CBX8 Chromodomain Inhibitor

(2019) Sijie Wang et al.   ACS Chemical Biology

Histone H2AK119 Mono-Ubiquitination Is Essential for Polycomb-Mediated Transcriptional Repression

(2019) Simone Tamburri et al.   MOLECULAR CELL

PRC1 Catalytic Activity Is Central to Polycomb System Function

(2019) Neil P. Blackledge et al.   MOLECULAR CELL

PRC1 Fine-tunes Gene Repression and Activation to Safeguard Skin Development and Stem Cell Specification

(2018) Idan Cohen et al.   Cell Stem Cell

The molecular selectivity of UNC3866 inhibitor for Polycomb CBX7 protein from molecular dynamics simulation

(2018) Hui Liu et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

De novo mutation inRING1with epigenetic effects on neurodevelopment

(2018) Sarah B. Pierce et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BMI1 regulates androgen receptor in prostate cancer independently of the polycomb repressive complex 1

(2018) Sen Zhu et al.   Nature Communications

A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes

(2018) Martina Foglizzo et al.   Nature Communications

Polycomb complexes associate with enhancers and promote oncogenic transcriptional programs in cancer through multiple mechanisms

(2018) Ho Lam Chan et al.   Nature Communications

Missense Mutations of the Pro65 Residue of PCGF2 Cause a Recognizable Syndrome Associated with Craniofacial, Neurological, Cardiovascular, and Skeletal Features

(2018) Peter D. Turnpenny et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Nuclear condensates of the Polycomb protein chromobox 2 (CBX2) assemble through phase separation

(2018) Roubina Tatavosian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oncohistones: drivers of pediatric cancers

(2017) Faizaan Mohammad et al.   GENES & DEVELOPMENT

Pathogenic ASXL1 somatic variants in reference databases complicate germline variant interpretation for Bohring-Opitz Syndrome

(2017) Colleen M. Carlston et al.   HUMAN MUTATION

Targeting BAP1: a new paradigm for mesothelioma

(2017) L.M. Schunselaar et al.   LUNG CANCER

ZC3H7B-BCOR high-grade endometrial stromal sarcomas: a report of 17 cases of a newly defined entity

(2017) Natasha Lewis et al.   MODERN PATHOLOGY

The interplay of epigenetic marks during stem cell differentiation and development

(2017) Yaser Atlasi et al.   NATURE REVIEWS GENETICS

PCGF3/5–PRC1 initiates Polycomb recruitment in X chromosome inactivation

(2017) Mafalda Almeida et al.   SCIENCE

Mutation of a nucleosome compaction region disrupts Polycomb-mediated axial patterning

(2017) Mei Sheng Lau et al.   SCIENCE

De Novo Truncating Variants in ASXL2 Are Associated with a Unique and Recognizable Clinical Phenotype

(2016) Vandana Shashi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Novel BCOR-MAML3 and ZC3H7B-BCOR Gene Fusions in Undifferentiated Small Blue Round Cell Sarcomas

(2016) Katja Specht et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Recurrent BCOR Internal Tandem Duplication and YWHAE-NUTM2B Fusions in Soft Tissue Undifferentiated Round Cell Sarcoma of Infancy

(2016) Yu-Chien Kao et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Polycomb Complex PRC1 Preserves Intestinal Stem Cell Identity by Sustaining Wnt/β-Catenin Transcriptional Activity

(2016) Fulvio Chiacchiera et al.   Cell Stem Cell

Truncation mutants of ASXL1 observed in myeloid malignancies are expressed at detectable protein levels

(2016) Daichi Inoue et al.   EXPERIMENTAL HEMATOLOGY

Dissecting the Roles of Polycomb Repressive Complex 2 Subunits in the Control of Skin Development

(2016) Katherine L. Dauber et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A detailed clinical analysis of 13 patients with AUTS2 syndrome further delineates the phenotypic spectrum and underscores the behavioural phenotype

(2016) Gea Beunders et al.   JOURNAL OF MEDICAL GENETICS

A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1

(2016) Jacob I Stuckey et al.   Nature Chemical Biology

Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status

(2016) Marie Schoumacher et al.   NATURE MEDICINE

The dynamic interactome and genomic targets of Polycomb complexes during stem-cell differentiation

(2016) Susan L Kloet et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Necessity of Chromatin: A View in Perspective

(2016) Vincenzo Pirrotta   Cold Spring Harbor Perspectives in Biology

Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2

(2016) Sarah Cooper et al.   Nature Communications

BAP1/ASXL1 recruitment and activation for H2A deubiquitination

(2016) Danny D. Sahtoe et al.   Nature Communications

The dynamic interactome and genomic targets of Polycomb complexes during stem-cell differentiation

(2016) Susan L Kloet et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A High-Density Map for Navigating the Human Polycomb Complexome

(2016) Simon Hauri et al.   Cell Reports

Role of the Polycomb Repressive Complex 2 (PRC2) in Transcriptional Regulation and Cancer

(2016) Anne Laugesen et al.   Cold Spring Harbor Perspectives in Medicine

RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes

(2016) Nathan R Rose et al.   eLife

Screening of CD96 and ASXL1 in 11 patients with Opitz C or Bohring-Opitz syndromes

(2015) Roser Urreizti et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Bohring-Opitz syndrome (BOS) with a newASXL1pathogenic variant: Review of the most prevalent molecular and phenotypic features of the syndrome

(2015) Silvana Beatriz Dangiolo et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain

(2015) Chunyan Ren et al.   CHEMISTRY & BIOLOGY

Chromatin deregulation in disease

(2015) Anne C. Mirabella et al.   CHROMOSOMA

Comprehensive review ofBAP1tumor predisposition syndrome with report of two new cases

(2015) K. Rai et al.   CLINICAL GENETICS

Gain-of-function mutation of chromatin regulators as a tumorigenic mechanism and an opportunity for therapeutic intervention

(2015) Chen Shen et al.   CURRENT OPINION IN ONCOLOGY

Regulation of Cellular Identity in Cancer

(2015) Nilotpal Roy et al.   DEVELOPMENTAL CELL

De novodominantASXL3mutations alter H2A deubiquitination and transcription in Bainbridge–Ropers syndrome

(2015) Anshika Srivastava et al.   HUMAN MOLECULAR GENETICS

The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer

(2015) Salima Daou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Consistent in-frame internal tandem duplications of BCOR characterize clear cell sarcoma of the kidney

(2015) Hitomi Ueno-Yokohata et al.   NATURE GENETICS

Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome

(2015) Stefan Schoenfelder et al.   NATURE GENETICS

Loss of BAP1 function leads to EZH2-dependent transformation

(2015) Lindsay M LaFave et al.   NATURE MEDICINE

Context-dependent actions of Polycomb repressors in cancer

(2015) M Koppens et al.   ONCOGENE

BMI1–RING1B is an autoinhibited RING E3 ubiquitin ligase

(2015) Asad M. Taherbhoy et al.   Nature Communications

Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1–BAP1 complex

(2015) Anand Balasubramani et al.   Nature Communications

Regulation of gene transcription by Polycomb proteins

(2015) S. Aranda et al.   Science Advances

Frequent ASXL2 mutations in acute myeloid leukemia patients with t(8;21)/RUNX1-RUNX1T1 chromosomal translocations

(2014) J.-B. Micol et al.   BLOOD

Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation

(2014) Neil P. Blackledge et al.   CELL

O-GlcNAcylation Prevents Aggregation of the Polycomb Group Repressor Polyhomeotic

(2014) Maria Cristina Gambetta et al.   DEVELOPMENTAL CELL

BRCA1-associated Protein 1 (BAP1) Deubiquitinase Antagonizes the Ubiquitin-mediated Activation of FoxK2 Target Genes

(2014) Yuki Okino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gene Silencing Triggers Polycomb Repressive Complex 2 Recruitment to CpG Islands Genome Wide

(2014) Eva Madi Riising et al.   MOLECULAR CELL

An AUTS2–Polycomb complex activates gene expression in the CNS

(2014) Zhonghua Gao et al.   NATURE

PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors

(2014) William Lee et al.   NATURE GENETICS

Histone H2A monoubiquitination promotes histone H3 methylation in Polycomb repression

(2014) Reinhard Kalb et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Exonic Deletions in AUTS2 Cause a Syndromic Form of Intellectual Disability and Suggest a Critical Role for the C Terminus

(2013) Gea Beunders et al.   AMERICAN JOURNAL OF HUMAN GENETICS

BCOR and BCORL1 mutations in myelodysplastic syndromes and related disorders

(2013) F. Damm et al.   BLOOD

Interplay between the Cancer Genome and Epigenome

(2013) Hui Shen et al.   CELL

SAM Domain Polymerization Links Subnuclear Clustering of PRC1 to Gene Silencing

(2013) Kyoichi Isono et al.   DEVELOPMENTAL CELL

Mutation in PHC1 implicates chromatin remodeling in primary microcephaly pathogenesis

(2013) Salma Awad et al.   HUMAN MOLECULAR GENETICS

Prognostic Score Including Gene Mutations in Chronic Myelomonocytic Leukemia

(2013) Raphaël Itzykson et al.   JOURNAL OF CLINICAL ONCOLOGY

Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo

(2013) Omar Abdel-Wahab et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Effects on survival of BAP1 and PBRM1 mutations in sporadic clear-cell renal-cell carcinoma: a retrospective analysis with independent validation

(2013) Payal Kapur et al.   LANCET ONCOLOGY

Polycomb-Dependent H3K27me1 and H3K27me2 Regulate Active Transcription and Enhancer Fidelity

(2013) Karin J. Ferrari et al.   MOLECULAR CELL

Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Structure of the Polycomb Group Protein PCGF1 in Complex with BCOR Reveals Basis for Binding Selectivity of PCGF Homologs

(2013) Sarah E. Junco et al.   STRUCTURE

The role of AUTS2 in neurodevelopment and human evolution

(2013) Nir Oksenberg et al.   TRENDS IN GENETICS

De novo truncating mutations in ASXL3 are associated with a novel clinical phenotype with similarities to Bohring-Opitz syndrome

(2013) Matthew N Bainbridge et al.   Genome Medicine

Function and Regulation of AUTS2, a Gene Implicated in Autism and Human Evolution

(2013) Nir Oksenberg et al.   PLoS Genetics

Rare De Novo Germline Copy-Number Variation in Testicular Cancer

(2012) Zsofia K. Stadler et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Polycomb Associates Genome-wide with a Specific RNA Polymerase II Variant, and Regulates Metabolic Genes in ESCs

(2012) Emily Brookes et al.   Cell Stem Cell

Polycomb Repressive Complex 1 (PRC1) Disassembles RNA Polymerase II Preinitiation Complexes

(2012) Lynn Lehmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer

(2012) Karim Nacerddine et al.   JOURNAL OF CLINICAL INVESTIGATION

PAX5-AUTS2: A recurrent fusion gene in childhood B-cell precursor acute lymphoblastic leukemia

(2012) Dagmar Denk et al.   LEUKEMIA RESEARCH

PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes

(2012) Zhonghua Gao et al.   MOLECULAR CELL

Loss of the Tumor Suppressor BAP1 Causes Myeloid Transformation

(2012) A. Dey et al.   SCIENCE

Transcription-Independent Function of Polycomb Group Protein PSC in Cell Cycle Control

(2012) A. Mohd-Sarip et al.   SCIENCE

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands

(2012) Anca M Farcas et al.   eLife

ASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN Favorable genetic category

(2011) K. H. Metzeler et al.   BLOOD

Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex

(2011) Matthew L Bentley et al.   EMBO JOURNAL

Prognostic Significance of ASXL1 Mutations in Patients With Myelodysplastic Syndromes

(2011) Felicitas Thol et al.   JOURNAL OF CLINICAL ONCOLOGY

Interaction Proteomics Analysis of Polycomb Proteins Defines Distinct PRC1 Complexes in Mammalian Cells

(2011) Julien Vandamme et al.   MOLECULAR & CELLULAR PROTEOMICS

The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma

(2011) Matthew Bott et al.   NATURE GENETICS

Germline BAP1 mutations predispose to malignant mesothelioma

(2011) Joseph R Testa et al.   NATURE GENETICS

Distinct clinical and biological features of de novo acute myeloid leukemia with additional sex comb-like 1 (ASXL1) mutations

(2010) W.-C. Chou et al.   BLOOD

Genome-wide Association Study of Prostate Cancer Mortality

(2010) K. L. Penney et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Tissue-Resident Adult Stem Cell Populations of Rapidly Self-Renewing Organs

(2010) Nick Barker et al.   Cell Stem Cell

Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia

(2010) J Boultwood et al.   LEUKEMIA

PAX5-AUTS2 fusion resulting from t(7;9)(q11.2;p13.2) can now be classified as recurrent in B cell acute lymphoblastic leukemia

(2010) E. Coyaud et al.   LEUKEMIA RESEARCH

The Ubiquitin Carboxyl Hydrolase BAP1 Forms a Ternary Complex with YY1 and HCF-1 and Is a Critical Regulator of Gene Expression

(2010) H. Yu et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB

(2010) Johanna C. Scheuermann et al.   NATURE

GC-Rich Sequence Elements Recruit PRC2 in Mammalian ES Cells

(2010) Eric M. Mendenhall et al.   PLoS Genetics

Mutations of polycomb-associated geneASXL1in myelodysplastic syndromes and chronic myelomonocytic leukaemia

(2009) Véronique Gelsi-Boyer et al.   BRITISH JOURNAL OF HAEMATOLOGY

Additional sex combs-like 1 belongs to the enhancer of trithorax and polycomb group and genetically interacts with Cbx2 in mice

(2009) C.L. Fisher et al.   DEVELOPMENTAL BIOLOGY

BCOR analysis in patients with OFCD and Lenz microphthalmia syndromes, mental retardation with ocular anomalies and cardiac laterality defects

(2009) Emma Hilton et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

BCOR regulates mesenchymal stem cell function by epigenetic mechanisms

(2009) Zhipeng Fan et al.   NATURE CELL BIOLOGY

Functional Conservation of Asxl2, a Murine Homolog for the Drosophila Enhancer of Trithorax and Polycomb Group Gene Asx

(2009) Heather A. Baskind et al.   PLoS One

RAWUL: A new ubiquitin-like domain in PRC1 Ring finger proteins that unveils putative plant and worm PRC1 orthologs

(2008) Luis Sanchez-Pulido et al.   BMC GENOMICS

Ezh1 and Ezh2 Maintain Repressive Chromatin through Different Mechanisms

(2008) Raphael Margueron et al.   MOLECULAR CELL

EZH1 Mediates Methylation on Histone H3 Lysine 27 and Complements EZH2 in Maintaining Stem Cell Identity and Executing Pluripotency

(2008) Xiaohua Shen et al.   MOLECULAR CELL