Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes
Authors
Keywords
-
Journal
Nature Communications
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-11-23
DOI
10.1038/s41467-020-19722-9
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Dynamic Competition of Polycomb and Trithorax in Transcriptional Programming
- (2020) Mitzi I. Kuroda et al. Annual Review of Biochemistry
- A potent nuclear export mechanism imposes USP16 cytoplasmic localization during interphase
- (2020) Nadine Sen Nkwe et al. JOURNAL OF CELL SCIENCE
- RYBP/YAF2-PRC1 complexes and histone H1-dependent chromatin compaction mediate propagation of H2AK119ub1 during cell division
- (2020) Jicheng Zhao et al. NATURE CELL BIOLOGY
- Structural Basis for the Activation of the Deubiquitinase Calypso by the Polycomb Protein ASX
- (2019) Inessa De et al. STRUCTURE
- BAP1 complex promotes transcription by opposing PRC1-mediated H2A ubiquitylation
- (2019) Antoine Campagne et al. Nature Communications
- An Adversarial DNA N6-Methyladenine-Sensor Network Preserves Polycomb Silencing
- (2019) Soo-Mi Kweon et al. MOLECULAR CELL
- Functional Landscape of PCGF Proteins Reveals Both RING1A/B-Dependent-and RING1A/B-Independent-Specific Activities
- (2019) Andrea Scelfo et al. MOLECULAR CELL
- Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression
- (2019) Nadezda A. Fursova et al. MOLECULAR CELL
- Singing for science
- (2019) Mike Z. He SCIENCE
- Dissecting the role of H3K27 acetylation and methylation in PRC2 mediated control of cellular identity
- (2019) Elisa Lavarone et al. Nature Communications
- Loss of PRC1 activity in different stem cell compartments activates a common transcriptional program with cell type–dependent outcomes
- (2019) Silvia Pivetti et al. Science Advances
- The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression
- (2019) Wenjing Su et al. CANCER CELL
- Advances in epigenetics link genetics to the environment and disease
- (2019) Giacomo Cavalli et al. NATURE
- PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation
- (2019) Evan Healy et al. MOLECULAR CELL
- BAP1 promotes stalled fork restart and cell survival via INO80 in response to replication stress
- (2019) Han-Sae Lee et al. BIOCHEMICAL JOURNAL
- Histone H2AK119 Mono-Ubiquitination Is Essential for Polycomb-Mediated Transcriptional Repression
- (2019) Simone Tamburri et al. MOLECULAR CELL
- PRC1 Catalytic Activity Is Central to Polycomb System Function
- (2019) Neil P. Blackledge et al. MOLECULAR CELL
- PRC1 Fine-tunes Gene Repression and Activation to Safeguard Skin Development and Stem Cell Specification
- (2018) Idan Cohen et al. Cell Stem Cell
- A Non-canonical BCOR-PRC1.1 Complex Represses Differentiation Programs in Human ESCs
- (2018) Zheng Wang et al. Cell Stem Cell
- Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy
- (2018) Lu Wang et al. NATURE MEDICINE
- Structures of human PRC2 with its cofactors AEBP2 and JARID2
- (2018) Vignesh Kasinath et al. SCIENCE
- BMI1 regulates androgen receptor in prostate cancer independently of the polycomb repressive complex 1
- (2018) Sen Zhu et al. Nature Communications
- Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis
- (2018) Shuhei Asada et al. Nature Communications
- MGA, L3MBTL2 and E2F6 determine genomic binding of the non-canonical Polycomb repressive complex PRC1.6
- (2018) Bastian Stielow et al. PLoS Genetics
- BAP1 links metabolic regulation of ferroptosis to tumour suppression
- (2018) Yilei Zhang et al. NATURE CELL BIOLOGY
- A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes
- (2018) Martina Foglizzo et al. Nature Communications
- Polycomb complexes associate with enhancers and promote oncogenic transcriptional programs in cancer through multiple mechanisms
- (2018) Ho Lam Chan et al. Nature Communications
- Loss of PRC1 induces higher-order opening of Hox loci independently of transcription during Drosophila embryogenesis
- (2018) Thierry Cheutin et al. Nature Communications
- The Lysine Demethylase dKDM2 Is Non-essential for Viability, but Regulates Circadian Rhythms in Drosophila
- (2018) Yani Zheng et al. Frontiers in Genetics
- The Implication of Early Chromatin Changes in X Chromosome Inactivation
- (2018) Jan Jakub Żylicz et al. CELL
- De novo recruitment of Polycomb-group proteins in Drosophila embryos
- (2018) Jumana Alhaj Abed et al. DEVELOPMENT
- Ubiquitination-Independent Repression of PRC1 Targets during Neuronal Fate Restriction in the Developing Mouse Neocortex
- (2018) Masafumi Tsuboi et al. DEVELOPMENTAL CELL
- Chromatin regulatory mechanisms and therapeutic opportunities in cancer
- (2018) Alfredo M. Valencia et al. NATURE CELL BIOLOGY
- Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1
- (2018) Salima Daou et al. Nature Communications
- BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation
- (2017) Angela Bononi et al. NATURE
- Chromatin dependencies in cancer and inflammation
- (2017) Ivan Marazzi et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Role of remodeling and spacing factor 1 in histone H2A ubiquitination-mediated gene silencing
- (2017) Zhuo Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- BAP1 inhibits the ER stress gene regulatory network and modulates metabolic stress response
- (2017) Fangyan Dai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PCGF3/5–PRC1 initiates Polycomb recruitment in X chromosome inactivation
- (2017) Mafalda Almeida et al. SCIENCE
- Kdm2b Regulates Somatic Reprogramming through Variant PRC1 Complex-Dependent Function
- (2017) Zhiwei Zhou et al. Cell Reports
- De Novo Truncating Variants in ASXL2 Are Associated with a Unique and Recognizable Clinical Phenotype
- (2016) Vandana Shashi et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Polycomb Complex PRC1 Preserves Intestinal Stem Cell Identity by Sustaining Wnt/β-Catenin Transcriptional Activity
- (2016) Fulvio Chiacchiera et al. Cell Stem Cell
- Molecular basis of PRC1 targeting to Polycomb response elements by PhoRC
- (2016) Felice Frey et al. GENES & DEVELOPMENT
- The molecular hallmarks of epigenetic control
- (2016) C. David Allis et al. NATURE REVIEWS GENETICS
- Regulation of DNA double-strand break repair by ubiquitin and ubiquitin-like modifiers
- (2016) Petra Schwertman et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Epigenetic balance of gene expression by Polycomb and COMPASS families
- (2016) Andrea Piunti et al. SCIENCE
- Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2
- (2016) Sarah Cooper et al. Nature Communications
- BAP1/ASXL1 recruitment and activation for H2A deubiquitination
- (2016) Danny D. Sahtoe et al. Nature Communications
- Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2
- (2016) Neil Justin et al. Nature Communications
- A High-Density Map for Navigating the Human Polycomb Complexome
- (2016) Simon Hauri et al. Cell Reports
- RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes
- (2016) Nathan R Rose et al. eLife
- Polycomb and trithorax opposition in development and disease
- (2016) Steven T. Poynter et al. Wiley Interdisciplinary Reviews-Developmental Biology
- Germline BAP1 Mutational Landscape of Asbestos-Exposed Malignant Mesothelioma Patients with Family History of Cancer
- (2015) Jill A. Ohar et al. CANCER RESEARCH
- Histone lysine demethylases inDrosophila melanogaster
- (2015) Andreana Holowatyj et al. FLY
- Transcriptional repression by PRC1 in the absence of H2A monoubiquitylation
- (2015) Ana Raquel Pengelly et al. GENES & DEVELOPMENT
- Genome-wide activities of Polycomb complexes control pervasive transcription
- (2015) Hun-Goo Lee et al. GENOME RESEARCH
- De novodominantASXL3mutations alter H2A deubiquitination and transcription in Bainbridge–Ropers syndrome
- (2015) Anshika Srivastava et al. HUMAN MOLECULAR GENETICS
- The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer
- (2015) Salima Daou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Polycomb RING1A- and RING1B-dependent histone H2A monoubiquitylation at pericentromeric regions promotes S-phase progression
- (2015) M. Bravo et al. JOURNAL OF CELL SCIENCE
- Transcriptional Elongation Factor ENL Phosphorylated by ATM Recruits Polycomb and Switches Off Transcription for DSB Repair
- (2015) Ayako Ui et al. MOLECULAR CELL
- Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation
- (2015) Serena Sanulli et al. MOLECULAR CELL
- Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2
- (2015) L. Jiao et al. SCIENCE
- Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1–BAP1 complex
- (2015) Anand Balasubramani et al. Nature Communications
- An integrative analysis of post-translational histone modifications in the marine diatom Phaeodactylum tricornutum
- (2015) Alaguraj Veluchamy et al. GENOME BIOLOGY
- The Polycomb group protein RING1B is overexpressed in ductal breast carcinoma and is required to sustain FAK steady state levels in breast cancer epithelial cells
- (2015) Almudena Bosch et al. Oncotarget
- Germline Mutations in BAP1 Impair Its Function in DNA Double-Strand Break Repair
- (2014) I. H. Ismail et al. CANCER RESEARCH
- Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation
- (2014) Neil P. Blackledge et al. CELL
- BRCA1-associated Protein 1 (BAP1) Deubiquitinase Antagonizes the Ubiquitin-mediated Activation of FoxK2 Target Genes
- (2014) Yuki Okino et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A developmental genetic analysis of the lysine demethylase KDM2 mutations in Drosophila melanogaster
- (2014) Yani Zheng et al. MECHANISMS OF DEVELOPMENT
- Requirement for PBAF in Transcriptional Repression and Repair at DNA Breaks in Actively Transcribed Regions of Chromatin
- (2014) Andreas Kakarougkas et al. MOLECULAR CELL
- Autodeubiquitination Protects the Tumor Suppressor BAP1 from Cytoplasmic Sequestration Mediated by the Atypical Ubiquitin Ligase UBE2O
- (2014) Nazar Mashtalir et al. MOLECULAR CELL
- Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome
- (2014) Robert K. McGinty et al. NATURE
- An AUTS2–Polycomb complex activates gene expression in the CNS
- (2014) Zhonghua Gao et al. NATURE
- Histone H2A monoubiquitination promotes histone H3 methylation in Polycomb repression
- (2014) Reinhard Kalb et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The forkhead transcription factor FOXK2 acts as a chromatin targeting factor for the BAP1-containing histone deubiquitinase complex
- (2014) Zongling Ji et al. NUCLEIC ACIDS RESEARCH
- The central role of EED in the orchestration of polycomb group complexes
- (2014) Qi Cao et al. Nature Communications
- Stabilization and targeting of INO80 to replication forks by BAP1 during normal DNA synthesis
- (2014) Han-Sae Lee et al. Nature Communications
- Targeting Polycomb to Pericentric Heterochromatin in Embryonic Stem Cells Reveals a Role for H2AK119u1 in PRC2 Recruitment
- (2014) Sarah Cooper et al. Cell Reports
- A Cbx8-Containing Polycomb Complex Facilitates the Transition to Gene Activation during ES Cell Differentiation
- (2014) Catherine Creppe et al. PLoS Genetics
- Germline BAP1 Mutations Predispose to Renal Cell Carcinomas
- (2013) Tatiana Popova et al. AMERICAN JOURNAL OF HUMAN GENETICS
- VAL- and AtBMI1-Mediated H2Aub Initiate the Switch from Embryonic to Postgerminative Growth in Arabidopsis
- (2013) Chao Yang et al. CURRENT BIOLOGY
- Structural basis for targeting the chromatin repressor Sfmbt to Polycomb response elements
- (2013) C. Alfieri et al. GENES & DEVELOPMENT
- Mutation in PHC1 implicates chromatin remodeling in primary microcephaly pathogenesis
- (2013) Salma Awad et al. HUMAN MOLECULAR GENETICS
- A Small Molecule Inhibitor of Polycomb Repressive Complex 1 Inhibits Ubiquitin Signaling at DNA Double-strand Breaks
- (2013) Ismail Hassan Ismail et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Aurora B Kinase and the Polycomb Protein Ring1B Combine to Regulate Active Promoters in Quiescent Lymphocytes
- (2013) Alberto Frangini et al. MOLECULAR CELL
- Regulation of DNA Damage Responses by Ubiquitin and SUMO
- (2013) Stephen P. Jackson et al. MOLECULAR CELL
- Fbxl10/Kdm2b Recruits Polycomb Repressive Complex 1 to CpG Islands and Regulates H2A Ubiquitylation
- (2013) Xudong Wu et al. MOLECULAR CELL
- Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes
- (2013) Jin He et al. NATURE CELL BIOLOGY
- Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas
- (2013) Yuchen Jiao et al. NATURE GENETICS
- Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair
- (2013) H. Yu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of the Polycomb Group Protein PCGF1 in Complex with BCOR Reveals Basis for Binding Selectivity of PCGF Homologs
- (2013) Sarah E. Junco et al. STRUCTURE
- The role of AUTS2 in neurodevelopment and human evolution
- (2013) Nir Oksenberg et al. TRENDS IN GENETICS
- De novo truncating mutations in ASXL3 are associated with a novel clinical phenotype with similarities to Bohring-Opitz syndrome
- (2013) Matthew N Bainbridge et al. Genome Medicine
- RYBP-PRC1 Complexes Mediate H2A Ubiquitylation at Polycomb Target Sites Independently of PRC2 and H3K27me3
- (2012) Lígia Tavares et al. CELL
- PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes
- (2012) Zhonghua Gao et al. MOLECULAR CELL
- Direct Recruitment of Polycomb Repressive Complex 1 to Chromatin by Core Binding Transcription Factors
- (2012) Ming Yu et al. MOLECULAR CELL
- BAP1 loss defines a new class of renal cell carcinoma
- (2012) Samuel Peña-Llopis et al. NATURE GENETICS
- CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage
- (2012) Ismail Hassan Ismail et al. NUCLEIC ACIDS RESEARCH
- Loss of the Tumor Suppressor BAP1 Causes Myeloid Transformation
- (2012) A. Dey et al. SCIENCE
- REST–Mediated Recruitment of Polycomb Repressor Complexes in Mammalian Cells
- (2012) Nikolaj Dietrich et al. PLoS Genetics
- Histone H2A Mono-Ubiquitination Is a Crucial Step to Mediate PRC1-Dependent Repression of Developmental Genes to Maintain ES Cell Identity
- (2012) Mitsuhiro Endoh et al. PLoS Genetics
- KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands
- (2012) Anca M Farcas et al. eLife
- The role of the histone H2A ubiquitinase Sce in Polycomb repression
- (2011) L. Gutierrez et al. DEVELOPMENT
- Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex
- (2011) Matthew L Bentley et al. EMBO JOURNAL
- REST Interacts with Cbx Proteins and Regulates Polycomb Repressive Complex 1 Occupancy at RE1 Elements
- (2011) X. Ren et al. MOLECULAR AND CELLULAR BIOLOGY
- L3MBTL2 Protein Acts in Concert with PcG Protein-Mediated Monoubiquitination of H2A to Establish a Repressive Chromatin Structure
- (2011) Patrick Trojer et al. MOLECULAR CELL
- De novo nonsense mutations in ASXL1 cause Bohring-Opitz syndrome
- (2011) Alexander Hoischen et al. NATURE GENETICS
- The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma
- (2011) Matthew Bott et al. NATURE GENETICS
- Germline BAP1 mutations and tumor susceptibility
- (2011) Alisa M Goldstein NATURE GENETICS
- Germline mutations in BAP1 predispose to melanocytic tumors
- (2011) Thomas Wiesner et al. NATURE GENETICS
- Germline BAP1 mutations predispose to malignant mesothelioma
- (2011) Joseph R Testa et al. NATURE GENETICS
- ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks
- (2010) Niraj M. Shanbhag et al. CELL
- Keeping Cell Identity in Arabidopsis Requires PRC1 RING-Finger Homologs that Catalyze H2A Monoubiquitination
- (2010) Fabian Bratzel et al. CURRENT BIOLOGY
- Jarid2 and PRC2, partners in regulating gene expression
- (2010) G. Li et al. GENES & DEVELOPMENT
- Polycomb complexes act redundantly to repress genomic repeats and genes
- (2010) M. Leeb et al. GENES & DEVELOPMENT
- BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair
- (2010) Ismail Hassan Ismail et al. JOURNAL OF CELL BIOLOGY
- BMI1 Confers Radioresistance to Normal and Cancerous Neural Stem Cells through Recruitment of the DNA Damage Response Machinery
- (2010) S. Facchino et al. JOURNAL OF NEUROSCIENCE
- The Ubiquitin Carboxyl Hydrolase BAP1 Forms a Ternary Complex with YY1 and HCF-1 and Is a Critical Regulator of Gene Expression
- (2010) H. Yu et al. MOLECULAR AND CELLULAR BIOLOGY
- Ring1B Compacts Chromatin Structure and Represses Gene Expression Independent of Histone Ubiquitination
- (2010) Ragnhild Eskeland et al. MOLECULAR CELL
- The DNA Damage Response: Making It Safe to Play with Knives
- (2010) Alberto Ciccia et al. MOLECULAR CELL
- Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB
- (2010) Johanna C. Scheuermann et al. NATURE
- Transcriptional activation of polycomb-repressed genes by ZRF1
- (2010) Holger Richly et al. NATURE
- A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage
- (2010) D. M. Chou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Frequent Mutation of BAP1 in Metastasizing Uveal Melanomas
- (2010) J. W. Harbour et al. SCIENCE
- Polycomb Group Targeting through Different Binding Partners of RING1B C-Terminal Domain
- (2010) Renjing Wang et al. STRUCTURE
- Defining the Human Deubiquitinating Enzyme Interaction Landscape
- (2009) Mathew E. Sowa et al. CELL
- Additional sex combs-like 1 belongs to the enhancer of trithorax and polycomb group and genetically interacts with Cbx2 in mice
- (2009) C.L. Fisher et al. DEVELOPMENTAL BIOLOGY
- The Deubiquitinating Enzyme BAP1 Regulates Cell Growth via Interaction with HCF-1
- (2009) Yuichi J. Machida et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells
- (2009) Li-Bing Song et al. JOURNAL OF CLINICAL INVESTIGATION
- BMI1 Sustains Human Glioblastoma Multiforme Stem Cell Renewal
- (2009) M. Abdouh et al. JOURNAL OF NEUROSCIENCE
- The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma
- (2009) Carles Martínez-Romero et al. JOURNAL OF PATHOLOGY
- dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing
- (2008) A. Lagarou et al. GENES & DEVELOPMENT
- Histone H2A Monoubiquitination Represses Transcription by Inhibiting RNA Polymerase II Transcriptional Elongation
- (2008) Wenlai Zhou et al. MOLECULAR CELL
- Cooperation between EZH2, NSPc1-mediated histone H2A ubiquitination and Dnmt1 in HOX gene silencing
- (2008) Xudong Wu et al. NUCLEIC ACIDS RESEARCH
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started