A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1
Authors
Keywords
-
Journal
Nature Chemical Biology
Volume 12, Issue 3, Pages 180-187
Publisher
Springer Nature
Online
2016-01-26
DOI
10.1038/nchembio.2007
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Identification of a Fragment-like Small Molecule Ligand for the Methyl-lysine Binding Protein, 53BP1
- (2015) Michael T. Perfetti et al. ACS Chemical Biology
- Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain
- (2015) Chunyan Ren et al. CHEMISTRY & BIOLOGY
- Genotranscriptomic meta-analysis of the Polycomb gene CBX2 in human cancers: initial evidence of an oncogenic role
- (2014) P-L Clermont et al. BRITISH JOURNAL OF CANCER
- Mind the Methyl: Methyllysine Binding Proteins in Epigenetic Regulation
- (2014) Tobias Wagner et al. ChemMedChem
- Chromodomain Antagonists That Target the Polycomb-Group Methyllysine Reader Protein Chromobox Homolog 7 (CBX7)
- (2014) Chakravarthi Simhadri et al. JOURNAL OF MEDICINAL CHEMISTRY
- Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia
- (2014) Panagiotis Ntziachristos et al. NATURE
- Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma
- (2014) Rintaro Hashizume et al. NATURE MEDICINE
- (R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells
- (2014) D. Barsyte-Lovejoy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Orally Bioavailable Chemical Probe of the Lysine Methyltransferases EZH2 and EZH1
- (2013) Kyle D. Konze et al. ACS Chemical Biology
- How good are my data and what is the resolution?
- (2013) Philip R. Evans et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Is JmjC Oxygenase Catalysis Limited to Demethylation?
- (2013) Richard J. Hopkinson et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Chromobox Homolog 4 Is Correlated with Prognosis and Tumor Cell Growth in Hepatocellular Carcinoma
- (2013) Boqing Wang et al. ANNALS OF SURGICAL ONCOLOGY
- Expression of chromobox homolog 7 (CBX7) is associated with poor prognosis in ovarian clear cell adenocarcinomaviaTRAIL-induced apoptotic pathway regulation
- (2013) Kanako Shinjo et al. INTERNATIONAL JOURNAL OF CANCER
- Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation
- (2013) Karin Klauke et al. NATURE CELL BIOLOGY
- Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain
- (2013) Lindsey I James et al. Nature Chemical Biology
- Target validation using chemical probes
- (2013) Mark E Bunnage et al. Nature Chemical Biology
- From Metadynamics to Dynamics
- (2013) Pratyush Tiwary et al. PHYSICAL REVIEW LETTERS
- Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay
- (2013) D. M. Molina et al. SCIENCE
- CBX7 is a tumor suppressor in mice and humans
- (2012) Floriana Forzati et al. JOURNAL OF CLINICAL INVESTIGATION
- Automated design of ligands to polypharmacological profiles
- (2012) Jérémy Besnard et al. NATURE
- Epigenetic protein families: a new frontier for drug discovery
- (2012) Cheryl H. Arrowsmith et al. NATURE REVIEWS DRUG DISCOVERY
- Androgen Receptor Drives Cellular Senescence
- (2012) Yelena Mirochnik et al. PLoS One
- Linking DNA Methyltransferases to Epigenetic Marks and Nucleosome Structure Genome-wide in Human Tumor Cells
- (2012) Bilian Jin et al. Cell Reports
- RYBP and Cbx7 Define Specific Biological Functions of Polycomb Complexes in Mouse Embryonic Stem Cells
- (2012) Lluis Morey et al. Cell Reports
- CBX8, a Polycomb Group Protein, Is Essential for MLL-AF9-Induced Leukemogenesis
- (2011) Jiaying Tan et al. CANCER CELL
- Interaction Proteomics Analysis of Polycomb Proteins Defines Distinct PRC1 Complexes in Mammalian Cells
- (2011) Julien Vandamme et al. MOLECULAR & CELLULAR PROTEOMICS
- Approaching a parameter-free metadynamics
- (2011) Bradley M. Dickson PHYSICAL REVIEW E
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Probing the Probes: Fitness Factors For Small Molecule Tools
- (2010) Paul Workman et al. CHEMISTRY & BIOLOGY
- Loss of the CBX7 protein expression correlates with a more aggressive phenotype in pancreatic cancer
- (2010) Eva Karamitopoulou et al. EUROPEAN JOURNAL OF CANCER
- The loss of the CBX7 gene expression represents an adverse prognostic marker for survival of colon carcinoma patients
- (2010) Pierlorenzo Pallante et al. EUROPEAN JOURNAL OF CANCER
- Recognition and Specificity Determinants of the Human Cbx Chromodomains
- (2010) Lilia Kaustov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Oncogenic role of the chromobox protein CBX7 in gastric cancer
- (2010) Xiao-Wei Zhang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Ring1B Compacts Chromatin Structure and Represses Gene Expression Independent of Histone Ubiquitination
- (2010) Ragnhild Eskeland et al. MOLECULAR CELL
- Selective inhibition of BET bromodomains
- (2010) Panagis Filippakopoulos et al. NATURE
- The art of the chemical probe
- (2010) Stephen V Frye Nature Chemical Biology
- Polycomb CBX7 Directly Controls Trimethylation of Histone H3 at Lysine 9 at the p16 Locus
- (2010) Qiang Li et al. PLoS One
- Folding Mechanism of Beta-Hairpin Trpzip2: Heterogeneity, Transition State and Folding Pathways
- (2009) Yi Xiao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- DNMT1 Silencing Affects Locus Specific DNA Methylation and Increases Prostate Cancer Derived PC3 Cell Invasiveness
- (2009) Ahmed Yaqinuddin et al. JOURNAL OF UROLOGY
- Down-regulation of DNMT3b in PC3 cells effects locus-specific DNA methylation, and represses cellular growth and migration
- (2008) Ahmed Yaqinuddin et al. Cancer Cell International
- Loss of the CBX7 Gene Expression Correlates with a Highly Malignant Phenotype in Thyroid Cancer
- (2008) P. Pallante et al. CANCER RESEARCH
- Specificity of the Chromodomain Y Chromosome Family of Chromodomains for Lysine-methylated ARK(S/T) Motifs
- (2008) Wolfgang Fischle et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation
- (2008) Berk Hess et al. Journal of Chemical Theory and Computation
- Changes in the Distributions and Dynamics of Polycomb Repressive Complexes during Embryonic Stem Cell Differentiation
- (2008) X. Ren et al. MOLECULAR AND CELLULAR BIOLOGY
- Polycomb Group Genes: Keeping Stem Cell Activity in Balance
- (2008) Martin Sauvageau et al. PLOS BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More