Scaffolding mechanism of arrestin-2 in the cRaf/MEK1/ERK signaling cascade
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Title
Scaffolding mechanism of arrestin-2 in the cRaf/MEK1/ERK signaling cascade
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 118, Issue 37, Pages e2026491118
Publisher
Proceedings of the National Academy of Sciences
Online
2021-09-15
DOI
10.1073/pnas.2026491118
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- (2018) Nicole A. Perry et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2017) Zhe Zhang et al. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
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- (2017) Elisabeth Cassier et al. eLife
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- (2017) Becky H. Lee et al. PLoS One
- The β-Arrestins: Multifunctional Regulators of G Protein-coupled Receptors
- (2016) Jeffrey S. Smith et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Different conformational dynamics of various active states of β-arrestin1 analyzed by hydrogen/deuterium exchange mass spectrometry
- (2015) Dong Kyun Kim et al. JOURNAL OF STRUCTURAL BIOLOGY
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- (2015) Yanyong Kang et al. NATURE
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- (2015) Joachim Granzin et al. Scientific Reports
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- Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide
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- (2013) Wolfgang Peti et al. PROTEIN SCIENCE
- Targeting the MAPK–RAS–RAF signaling pathway in cancer therapy
- (2012) Libero Santarpia et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- ERK1/2 MAP kinases: Structure, function, and regulation
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- A Single Mutation in Arrestin-2 Prevents ERK1/2 Activation by Reducing c-Raf1 Binding
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- (2010) Sean R. Marcsisin et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Mechanistic principles of RAF kinase signaling
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- Identification of small-molecule inhibitors of the JIP–JNK interaction
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- MEK1 Binds Directly to βArrestin1, Influencing Both Its Phosphorylation by ERK and the Timing of Its Isoprenaline-stimulated Internalization
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