Arrestin-3 scaffolding of the JNK3 cascade suggests a mechanism for signal amplification

Targeted Elimination of G Proteins and Arrestins Defines Their Specific Contributions to Both Intensity and Duration of G Protein-coupled Receptor Signaling

(2016) Elisa Alvarez-Curto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Monitoring G protein-coupled receptor and β-arrestin trafficking in live cells using enhanced bystander BRET

(2016) Yoon Namkung et al.   Nature Communications

cJun N-terminal kinase (JNK) phosphorylation of serine 36 is critical for p66Shc activation

(2016) Sana Khalid et al.   Scientific Reports

Arrestin-3 binds the MAP kinase JNK3α2 via multiple sites on both domains

(2014) Xuanzhi Zhan et al.   CELLULAR SIGNALLING

Visualization of arrestin recruitment by a G-protein-coupled receptor

(2014) Arun K. Shukla et al.   NATURE

Logarithmic and Power Law Input-Output Relations in Sensory Systems with Fold-Change Detection

(2014) Miri Adler et al.   PLoS Computational Biology

JNK3 Enzyme Binding to Arrestin-3 Differentially Affects the Recruitment of Upstream Mitogen-activated Protein (MAP) Kinase Kinases

(2013) Xuanzhi Zhan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Arrestin-3 Binds c-Jun N-terminal Kinase 1 (JNK1) and JNK2 and Facilitates the Activation of These Ubiquitous JNK Isoforms in Cells via Scaffolding

(2013) Seunghyi Kook et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Programming biological models in Python using PySB

(2013) C. F. Lopez et al.   Molecular Systems Biology

Silent Scaffolds

(2012) Maya Breitman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How scaffolds shape MAPK signaling: what we know and opportunities for systems approaches

(2012) Franziska Witzel et al.   Frontiers in Physiology

Molecular Interaction Studies Using Microscale Thermophoresis

(2011) Moran Jerabek-Willemsen et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Ubiquitin Ligase Parkin Promotes Mdm2–Arrestin Interaction but Inhibits Arrestin Ubiquitination

(2011) M. Rafiuddin Ahmed et al.   BIOCHEMISTRY

Crystal Structure of Arrestin-3 Reveals the Basis of the Difference in Receptor Binding Between Two Non-visual Subtypes

(2011) Xuanzhi Zhan et al.   JOURNAL OF MOLECULAR BIOLOGY

The Effect of Arrestin Conformation on the Recruitment of c-Raf1, MEK1, and ERK1/2 Activation

(2011) Sergio Coffa et al.   PLoS One

Scaffold Proteins: Hubs for Controlling the Flow of Cellular Information

(2011) M. C. Good et al.   SCIENCE

Beyond Desensitization: Physiological Relevance of Arrestin-Dependent Signaling

(2010) L. M. Luttrell et al.   PHARMACOLOGICAL REVIEWS

Protein-binding assays in biological liquids using microscale thermophoresis

(2010) Christoph J. Wienken et al.   Nature Communications

The Ste5 Scaffold Directs Mating Signaling by Catalytically Unlocking the Fus3 MAP Kinase for Activation

(2009) Matthew Good et al.   CELL

Structure of an Arrestin2-Clathrin Complex Reveals a Novel Clathrin Binding Domain That Modulates Receptor Trafficking

(2009) Dong Soo Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How Mitogen-Activated Protein Kinases Recognize and Phosphorylate Their Targets: A QM/MM Study

(2009) Adrian Gustavo Turjanski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Protein scaffolds in MAP kinase signalling

(2008) Matthew D. Brown et al.   CELLULAR SIGNALLING

How Does Arrestin Assemble MAPKs into a Signaling Complex?

(2008) Xiufeng Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of c-Jun N-terminal kinase (JNK) by widely used specific p38 MAPK inhibitors SB202190 and SB203580: A MLK-3-MKK7-dependent mechanism

(2007) Harish Muniyappa et al.   CELLULAR SIGNALLING