Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

Structure of the Angiotensin Receptor Revealed by Serial Femtosecond Crystallography

(2015) Haitao Zhang et al.   CELL

Visualization of arrestin recruitment by a G-protein-coupled receptor

(2014) Arun K. Shukla et al.   NATURE

Preparation of microcrystals in lipidic cubic phase for serial femtosecond crystallography

(2014) Wei Liu et al.   Nature Protocols

Functional map of arrestin-1 at single amino acid resolution

(2014) Martin K. Ostermaier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography

(2014) Uwe Weierstall et al.   Nature Communications

Space-group and origin ambiguity in macromolecular structures with pseudo-symmetry and its treatment with the programZanuda

(2014) Andrey A. Lebedev et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Cheetah: software for high-throughput reduction and analysis of serial femtosecond X-ray diffraction data

(2014) Anton Barty et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Crystallographic data processing for free-electron laser sources

(2013) Thomas A. White et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Genetically Encoded Chemical Probes in Cells Reveal the Binding Path of Urocortin-I to CRF Class B GPCR

(2013) Irene Coin et al.   CELL

Time Window Expansion for HDX Analysis of an Intrinsically Disordered Protein

(2013) Devrishi Goswami et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Crystal structure of pre-activated arrestin p44

(2013) Yong Ju Kim et al.   NATURE

Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide

(2013) Arun K. Shukla et al.   NATURE

Involvement of distinct arrestin-1 elements in binding to different functional forms of rhodopsin

(2013) T. Zhuang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Simple piggyBac transposon-based mammalian cell expression system for inducible protein production

(2013) Z. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for Molecular Recognition at Serotonin Receptors

(2013) C. Wang et al.   SCIENCE

Structural Features for Functional Selectivity at Serotonin Receptors

(2013) D. Wacker et al.   SCIENCE

Serial Femtosecond Crystallography of G Protein-Coupled Receptors

(2013) W. Liu et al.   SCIENCE

Protein Conformation Ensembles Monitored by HDX Reveal a Structural Rationale for Abscisic Acid Signaling Protein Affinities and Activities

(2013) Graham M. West et al.   STRUCTURE

Statistical quality indicators for electron-density maps

(2012) Ian J. Tickle   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure and activation of rhodopsin

(2012) X Edward Zhou et al.   ACTA PHARMACOLOGICA SINICA

Structure-Function of the G Protein–Coupled Receptor Superfamily

(2012) Vsevolod Katritch et al.   Annual Review of Pharmacology and Toxicology

Insights into the activation mechanism of the visual receptor rhodopsin

(2012) Steven O. Smith   BIOCHEMICAL SOCIETY TRANSACTIONS

CrystFEL: a software suite for snapshot serial crystallography

(2012) Thomas A. White et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

HDX Workbench: Software for the Analysis of H/D Exchange MS Data

(2012) Bruce D. Pascal et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Ultra-precise characterization of LCLS hard X-ray focusing mirrors by high resolution slope measuring deflectometry

(2012) Frank Siewert et al.   OPTICS EXPRESS

Conformation of receptor-bound visual arrestin

(2012) M. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Organization of the Influenza Virus Replication Machinery

(2012) A. Moeller et al.   SCIENCE

Biased Signaling Pathways in  2-Adrenergic Receptor Characterized by 19F-NMR

(2012) J. J. Liu et al.   SCIENCE

High-Resolution Protein Structure Determination by Serial Femtosecond Crystallography

(2012) S. Boutet et al.   SCIENCE

Linking Crystallographic Model and Data Quality

(2012) P. A. Karplus et al.   SCIENCE

Distinct loops in arrestin differentially regulate ligand binding within the GPCR opsin

(2012) Martha E. Sommer et al.   Nature Communications

Structure-factor analysis of femtosecond microdiffraction patterns from protein nanocrystals

(2011) Richard A. Kirian et al.   ACTA CRYSTALLOGRAPHICA SECTION A

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

(2011) T. Geoff G. Battye et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Molecular Mechanism of β-Arrestin-Biased Agonism at Seven-Transmembrane Receptors

(2011) Eric Reiter et al.   Annual Review of Pharmacology and Toxicology

Biased signalling and allosteric machines: new vistas and challenges for drug discovery

(2011) Terry P Kenakin   BRITISH JOURNAL OF PHARMACOLOGY

Development of an Automated High Throughput LCP-FRAP Assay to Guide Membrane Protein Crystallization in Lipid Mesophases

(2011) Fei Xu et al.   CRYSTAL GROWTH & DESIGN

Crystal structure of metarhodopsin II

(2011) Hui-Woog Choe et al.   NATURE

The structural basis of agonist-induced activation in constitutively active rhodopsin

(2011) Jörg Standfuss et al.   NATURE

Crystal structure of the β2 adrenergic receptor–Gs protein complex

(2011) Søren G. F. Rasmussen et al.   NATURE

Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II

(2011) X. Deupi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational dynamics of helix 8 in the GPCR rhodopsin controls arrestin activation in the desensitization process

(2011) K. Kirchberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The functional cycle of visual arrestins in photoreceptor cells

(2011) Vsevolod V. Gurevich et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Structure of an Agonist-Bound Human A2A Adenosine Receptor

(2011) F. Xu et al.   SCIENCE

Integration, scaling, space-group assignment and post-refinement

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Monomeric Rhodopsin Is Sufficient for Normal Rhodopsin Kinase (GRK1) Phosphorylation and Arrestin-1 Binding

(2010) Timothy H. Bayburt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Coherent X-ray Imaging (CXI) instrument at the Linac Coherent Light Source (LCLS)

(2010) Sébastien Boutet et al.   NEW JOURNAL OF PHYSICS

A minimal peptide substrate in biotin holoenzyme synthetase-catalyzed biotinylation

(2010) Dorothy Beckett et al.   PROTEIN SCIENCE

Development of a new physics-based internal coordinate mechanics force field and its application to protein loop modeling

(2010) Yelena A. Arnautova et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Appion: An integrated, database-driven pipeline to facilitate EM image processing

(2009) Gabriel C. Lander et al.   JOURNAL OF STRUCTURAL BIOLOGY

DoG Picker and TiltPicker: Software tools to facilitate particle selection in single particle electron microscopy

(2009) N.R. Voss et al.   JOURNAL OF STRUCTURAL BIOLOGY

Crystallizing membrane proteins using lipidic mesophases

(2009) Martin Caffrey et al.   Nature Protocols

Structural origin of weakly ordered nitroxide motion in spin-labeled proteins

(2009) Mark R. Fleissner et al.   PROTEIN SCIENCE

Structural Impact of the E113Q Counterion Mutation on the Activation and Deactivation Pathways of the G Protein-coupled Receptor Rhodopsin

(2008) Jörg Standfuss et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal structure of opsin in its G-protein-interacting conformation

(2008) Patrick Scheerer et al.   NATURE

Crystal structure of the ligand-free G-protein-coupled receptor opsin

(2008) Jung Hee Park et al.   NATURE

Image processing for electron microscopy single-particle analysis using XMIPP

(2008) Sjors H W Scheres et al.   Nature Protocols

High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation

(2008) C. Altenbach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromosomal transposition of PiggyBac in mouse embryonic stem cells

(2008) W. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microscale Fluorescent Thermal Stability Assay for Membrane Proteins

(2008) Alexander I. Alexandrov et al.   STRUCTURE