G-quadruplex binders as cytostatic modulators of innate immune genes in cancer cells
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Title
G-quadruplex binders as cytostatic modulators of innate immune genes in cancer cells
Authors
Keywords
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Journal
NUCLEIC ACIDS RESEARCH
Volume 49, Issue 12, Pages 6673-6686
Publisher
Oxford University Press (OUP)
Online
2021-05-29
DOI
10.1093/nar/gkab500
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Related references
Note: Only part of the references are listed.- Emerging roles for R-loop structures in the management of topological stress
- (2020) Frederic Chedin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mono-hydrazone based G-quadruplex selective ligands induce DNA damage and genome instability in human cancer cells
- (2020) Jussara Amato et al. JOURNAL OF MEDICINAL CHEMISTRY
- Small-molecule G-quadruplex stabilizers reveal a novel pathway of autophagy regulation in neurons
- (2020) Jose F Moruno-Manchon et al. eLife
- Regulation of autophagy by DNA G-quadruplexes
- (2020) Pauline Lejault et al. Autophagy
- The regulation and functions of DNA and RNA G-quadruplexes
- (2020) Dhaval Varshney et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Molecular mechanisms and cellular functions of cGAS–STING signalling
- (2020) Karl-Peter Hopfner et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- G-quadruplex, Friend or Foe: The Role of the G-quartet in Anticancer Strategies
- (2020) Josué Carvalho et al. TRENDS IN MOLECULAR MEDICINE
- A Genetic Map of the Response to DNA Damage in Human Cells
- (2020) Michele Olivieri et al. CELL
- Landscape of G-quadruplex DNA structural regions in breast cancer
- (2020) Robert Hänsel-Hertsch et al. NATURE GENETICS
- Comprehensive elaboration of the cGAS-STING signaling axis in cancer development and immunotherapy
- (2020) Juyan Zheng et al. Molecular Cancer
- DNA Quadruple Helices in Nanotechnology
- (2019) Jean-Louis Mergny et al. CHEMICAL REVIEWS
- Modulation of the ATM/autophagy pathway by a G-quadruplex ligand tips the balance between senescence and apoptosis in cancer cells
- (2019) Jennifer Beauvarlet et al. NUCLEIC ACIDS RESEARCH
- The DNA damage response acts as a safeguard against harmful DNA–RNA hybrids of different origins
- (2019) Sonia Barroso et al. EMBO REPORTS
- DNA sensing by the cGAS–STING pathway in health and disease
- (2019) Mona Motwani et al. NATURE REVIEWS GENETICS
- Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype
- (2019) Daehwan Kim et al. NATURE BIOTECHNOLOGY
- R-Loops Promote Antisense Transcription across the Mammalian Genome
- (2019) Sue Mei Tan-Wong et al. MOLECULAR CELL
- Harnessing innate immunity in cancer therapy
- (2019) Olivier Demaria et al. NATURE
- The Cytosolic DNA-Sensing cGAS–STING Pathway in Cancer
- (2019) John Kwon et al. Cancer Discovery
- The Immune Landscape of Cancer
- (2018) Vésteinn Thorsson et al. IMMUNITY
- Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage mediated cytokine production
- (2018) Hiroyasu Konno et al. ONCOGENE
- Targeting STING with covalent small-molecule inhibitors
- (2018) Simone M. Haag et al. NATURE
- DNA damage and genome instability by G-quadruplex ligands are mediated by R loops in human cancer cells
- (2018) Alessio De Magis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- cGAS surveillance of micronuclei links genome instability to innate immunity
- (2017) Karen J. Mackenzie et al. NATURE
- Mitotic progression following DNA damage enables pattern recognition within micronuclei
- (2017) Shane M. Harding et al. NATURE
- CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours
- (2017) Hong Xu et al. Nature Communications
- Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells
- (2016) Marco De Simone et al. IMMUNITY
- Quadruplex Nucleic Acids as Novel Therapeutic Targets
- (2016) Stephen Neidle JOURNAL OF MEDICINAL CHEMISTRY
- Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer
- (2016) Eileen E. Parkes et al. JNCI-Journal of the National Cancer Institute
- G-quadruplexes and helicases
- (2016) Oscar Mendoza et al. NUCLEIC ACIDS RESEARCH
- Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA
- (2016) Morten Scheibye-Knudsen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activation of STING requires palmitoylation at the Golgi
- (2016) Kojiro Mukai et al. Nature Communications
- Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer
- (2016) Eileen E. Parkes et al. JNCI-Journal of the National Cancer Institute
- Innate Immune Recognition of Cancer
- (2015) Seng-Ryong Woo et al. Annual Review of Immunology
- Linking Micronuclei to Chromosome Fragmentation
- (2015) Emily M. Hatch et al. CELL
- Chromothripsis from DNA damage in micronuclei
- (2015) Cheng-Zhong Zhang et al. NATURE
- StringTie enables improved reconstruction of a transcriptome from RNA-seq reads
- (2015) Mihaela Pertea et al. NATURE BIOTECHNOLOGY
- Orchestrating high-throughput genomic analysis with Bioconductor
- (2015) Wolfgang Huber et al. NATURE METHODS
- Robust enumeration of cell subsets from tissue expression profiles
- (2015) Aaron M Newman et al. NATURE METHODS
- R loops: new modulators of genome dynamics and function
- (2015) José M. Santos-Pereira et al. NATURE REVIEWS GENETICS
- Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation
- (2015) S. Liu et al. SCIENCE
- Breaking bad: R-loops and genome integrity
- (2015) Julie Sollier et al. TRENDS IN CELL BIOLOGY
- Trimmomatic: a flexible trimmer for Illumina sequence data
- (2014) Anthony M. Bolger et al. BIOINFORMATICS
- A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expression
- (2014) K. Skourti-Stathaki et al. GENES & DEVELOPMENT
- Innate immune regulation by STAT-mediated transcriptional mechanisms
- (2014) Haiyan S. Li et al. IMMUNOLOGICAL REVIEWS
- iRegulon: From a Gene List to a Gene Regulatory Network Using Large Motif and Track Collections
- (2014) Rekin's Janky et al. PLoS Computational Biology
- Mast Cells Boost Myeloid-Derived Suppressor Cell Activity and Contribute to the Development of Tumor-Favoring Microenvironment
- (2014) L. Danelli et al. Cancer Immunology Research
- Solution Structure of a G-quadruplex Bound to the Bisquinolinium Compound Phen-DC3
- (2013) Wan Jun Chung et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Turning Tumors into Vaccines: Co-opting the Innate Immune System
- (2013) Jasper G. van den Boorn et al. IMMUNITY
- Mechanism of Action of Conventional and Targeted Anticancer Therapies: Reinstating Immunosurveillance
- (2013) Laurence Zitvogel et al. IMMUNITY
- CD4+ follicular helper T cell infiltration predicts breast cancer survival
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- Single Nucleotide Polymorphisms of Human STING Can Affect Innate Immune Response to Cyclic Dinucleotides
- (2013) Guanghui Yi et al. PLoS One
- Autophagy acts as a safeguard mechanism against G-quadruplex ligand-mediated DNA damage
- (2012) Nicola Ivan Orlotti et al. Autophagy
- Comprehensive molecular portraits of human breast tumours
- (2012) Daniel C. Koboldt et al. NATURE
- Small-molecule–induced DNA damage identifies alternative DNA structures in human genes
- (2012) Raphaël Rodriguez et al. Nature Chemical Biology
- G4LDB: a database for discovering and studying G-quadruplex ligands
- (2012) Qian Li et al. NUCLEIC ACIDS RESEARCH
- Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells
- (2012) Sebastian Müller et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
- (2012) J. Wu et al. SCIENCE
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- (2011) L Jin et al. GENES AND IMMUNITY
- Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
- (2011) Shankar Balasubramanian et al. NATURE REVIEWS DRUG DISCOVERY
- Lymphocytes in cancer development: Polarization towards pro-tumor immunity
- (2009) Brian Ruffell et al. CYTOKINE & GROWTH FACTOR REVIEWS
- G-quadruplex ligand SYUIQ-5 induces autophagy by telomere damage and TRF2 delocalization in cancer cells
- (2009) W.-J. Zhou et al. MOLECULAR CANCER THERAPEUTICS
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