Innate immune regulation by STAT-mediated transcriptional mechanisms

In vivo evidence for an instructive role of fms-like tyrosine kinase-3 (FLT3) ligand in hematopoietic development

(2014) P. Tsapogas et al.   HAEMATOLOGICA

Subsets of Myeloid-Derived Suppressor Cells in Tumor-Bearing Mice

(2014) J.-I. Youn et al.   JOURNAL OF IMMUNOLOGY

Tumor-Induced STAT3 Signaling in Myeloid Cells Impairs Dendritic Cell Generation by Decreasing PKC II Abundance

(2014) M. R. Farren et al.   Science Signaling

The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients

(2013) David Vasquez-Dunddel et al.   JOURNAL OF CLINICAL INVESTIGATION

Multicolor fate mapping of Langerhans cell homeostasis

(2013) Clément Ghigo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A type I IFN–Flt3 ligand axis augments plasmacytoid dendritic cell development from common lymphoid progenitors

(2013) Yi-Ling Chen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Origin of monocytes and macrophages in a committed progenitor

(2013) Jan Hettinger et al.   NATURE IMMUNOLOGY

Reply to: "Can DCs be distinguished from macrophages by molecular signatures?"

(2013) Gwen Randolph et al.   NATURE IMMUNOLOGY

The transcription factor STAT5 is critical in dendritic cells for the development of TH2 but not TH1 responses

(2013) Bryan D Bell et al.   NATURE IMMUNOLOGY

Convergent differentiation: myeloid and lymphoid pathways to murine plasmacytoid dendritic cells

(2012) P. Sathe et al.   BLOOD

The signal transducers STAT5 and STAT3 control expression of Id2 and E2-2 during dendritic cell development

(2012) H. S. Li et al.   BLOOD

Demand-adapted regulation of early hematopoiesis in infection and inflammation

(2012) H. Takizawa et al.   BLOOD

Plasmacytoid Dendritic Cells Promote Immunosuppression in Ovarian Cancer via ICOS Costimulation of Foxp3+ T-Regulatory Cells

(2012) C. Conrad et al.   CANCER RESEARCH

Human airway epithelial cell innate immunity: relevance to asthma

(2012) Jeremy A Hirota et al.   CURRENT OPINION IN IMMUNOLOGY

GM-CSF Controls Nonlymphoid Tissue Dendritic Cell Homeostasis but Is Dispensable for the Differentiation of Inflammatory Dendritic Cells

(2012) Melanie Greter et al.   IMMUNITY

The JAK-STAT Pathway at Twenty

(2012) George R. Stark et al.   IMMUNITY

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

Cross-presenting CD103+ dendritic cells are protected from influenza virus infection

(2012) Julie Helft et al.   JOURNAL OF CLINICAL INVESTIGATION

G-CSF-activated STAT3 enhances production of the chemokine MIP-2 in bone marrow neutrophils

(2012) Hoainam T. Nguyen-Jackson et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A STATus report on DC development

(2012) H. S. Li et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors

(2012) C C Bain et al.   Mucosal Immunology

IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia

(2012) Yaming Wang et al.   NATURE IMMUNOLOGY

Deciphering the transcriptional network of the dendritic cell lineage

(2012) Jennifer C Miller et al.   NATURE IMMUNOLOGY

Nucleic acid-containing amyloid fibrils potently induce type I interferon and stimulate systemic autoimmunity

(2012) J. Di Domizio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasmacytoid dendritic cells control T-cell response to chronic viral infection

(2012) L. Cervantes-Barragan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cross-dressed CD8 +/CD103+ dendritic cells prime CD8+ T cells following vaccination

(2012) L. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

Conditional Stat1 Ablation Reveals the Importance of Interferon Signaling for Immunity to Listeria monocytogenes Infection

(2012) Elisabeth Kernbauer et al.   PLoS Pathogens

Plasmacytoid Dendritic Cells: Recent Progress and Open Questions

(2011) Boris Reizis et al.   Annual Review of Immunology

Cell-intrinsic role for IFN- -STAT1 signals in regulating murine Peyer patch plasmacytoid dendritic cells and conditioning an inflammatory response

(2011) H. S. Li et al.   BLOOD

Therapeutic applications of macrophage colony-stimulating factor-1 (CSF-1) and antagonists of CSF-1 receptor (CSF-1R) signaling

(2011) D. A. Hume et al.   BLOOD

Dendritic Cell and Macrophage Heterogeneity In Vivo

(2011) Daigo Hashimoto et al.   IMMUNITY

Host type I IFN signals are required for antitumor CD8+T cell responses through CD8α+dendritic cells

(2011) Mercedes B. Fuertes et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Type I interferon is selectively required by dendritic cells for immune rejection of tumors

(2011) Mark S. Diamond et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Critical Role for Macrophages in Promotion of Urethane-Induced Lung Carcinogenesis

(2011) R. Zaynagetdinov et al.   JOURNAL OF IMMUNOLOGY

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

(2011) Bin-Zhi Qian et al.   NATURE

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

(2011) Thomas Krausgruber et al.   NATURE IMMUNOLOGY

IRF8Mutations and Human Dendritic-Cell Immunodeficiency

(2011) Sophie Hambleton et al.   NEW ENGLAND JOURNAL OF MEDICINE

Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of TH2 Inflammation

(2011) S. J. Jenkins et al.   SCIENCE

Monocyte trafficking in acute and chronic inflammation

(2011) Molly A. Ingersoll et al.   TRENDS IN IMMUNOLOGY

Hematopoietic growth factors: ESMO Clinical Practice Guidelines for the applications

(2010) J. Crawford et al.   ANNALS OF ONCOLOGY

STAT3 controls the neutrophil migratory response to CXCR2 ligands by direct activation of G-CSF-induced CXCR2 expression and via modulation of CXCR2 signal transduction

(2010) H. Nguyen-Jackson et al.   BLOOD

STAT3 controls myeloid progenitor growth during emergency granulopoiesis

(2010) H. Zhang et al.   BLOOD

An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation

(2010) K. P. A. MacDonald et al.   BLOOD

Macrophages, innate immunity and cancer: balance, tolerance, and diversity

(2010) Alberto Mantovani et al.   CURRENT OPINION IN IMMUNOLOGY

Fate Mapping Reveals Separate Origins of T Cells and Myeloid Lineages in the Thymus

(2010) Susan M. Schlenner et al.   IMMUNITY

Continuous Expression of the Transcription Factor E2-2 Maintains the Cell Fate of Mature Plasmacytoid Dendritic Cells

(2010) Hiyaa S. Ghosh et al.   IMMUNITY

Neutrophils, from Marrow to Microbes

(2010) Niels Borregaard   IMMUNITY

Instructive cytokine signals in dendritic cell lineage commitment

(2010) Michael A. Schmid et al.   IMMUNOLOGICAL REVIEWS

Origin and development of dendritic cells

(2010) Kang Liu et al.   IMMUNOLOGICAL REVIEWS

Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors

(2010) Jinfang Zhu et al.   IMMUNOLOGICAL REVIEWS

Ontogeny and homeostasis of Langerhans cells

(2010) Florent Ginhoux et al.   IMMUNOLOGY AND CELL BIOLOGY

GM-CSF–dependent, CD103+dermal dendritic cells play a critical role in Th effector cell differentiation after subcutaneous immunization

(2010) Irah L. King et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Peripheral CD103+dendritic cells form a unified subset developmentally related to CD8α+conventional dendritic cells

(2010) Brian T. Edelson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Plasmacytoid dendritic cells sense skin injury and promote wound healing through type I interferons

(2010) Josh Gregorio et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dendritic Cell (DC)-Specific Targeting Reveals Stat3 as a Negative Regulator of DC Function

(2010) Jessica A. Melillo et al.   JOURNAL OF IMMUNOLOGY

Quiescent haematopoietic stem cells are activated by IFN-γ in response to chronic infection

(2010) Megan T. Baldridge et al.   NATURE

Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation

(2010) Abdul Hakkim et al.   Nature Chemical Biology

The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

(2010) Takashi Satoh et al.   NATURE IMMUNOLOGY

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Arginine Usage in Mycobacteria-Infected Macrophages Depends on Autocrine-Paracrine Cytokine Signaling

(2010) J. E. Qualls et al.   Science Signaling

Antimicrobial Peptides: Primeval Molecules or Future Drugs?

(2010) Brian M. Peters et al.   PLoS Pathogens

The concerted action of GM-CSF and Flt3-ligand on in vivo dendritic cell homeostasis

(2009) D. Kingston et al.   BLOOD

Dendritic cell homeostasis

(2009) M. Merad et al.   BLOOD

Persistently Activated Stat3 Maintains Constitutive NF-κB Activity in Tumors

(2009) Heehyoung Lee et al.   CANCER CELL

Identification of a Subpopulation of Macrophages in Mammary Tumor-Bearing Mice That Are Neither M1 nor M2 and Are Less Differentiated

(2009) M. Torroella-Kouri et al.   CANCER RESEARCH

The origin and development of nonlymphoid tissue CD103+DCs

(2009) Florent Ginhoux et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD207+CD103+dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells

(2009) Sandrine Henri et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dendritic Cells Require STAT-1 Phosphorylated at Its Transactivating Domain for the Induction of Peptide-Specific CTL

(2009) A. Pilz et al.   JOURNAL OF IMMUNOLOGY

Mechanism Regulating Reactive Oxygen Species in Tumor-Induced Myeloid-Derived Suppressor Cells

(2009) C. A. Corzo et al.   JOURNAL OF IMMUNOLOGY

IFNα activates dormant haematopoietic stem cells in vivo

(2009) Marieke A. G. Essers et al.   NATURE

Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells

(2009) Sammy Bedoui et al.   NATURE IMMUNOLOGY

Alternative Activation of Macrophages: An Immunologic Functional Perspective

(2008) Fernando O. Martinez et al.   Annual Review of Immunology

Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity

(2008) K. Movahedi et al.   BLOOD

Transcription Factor E2-2 Is an Essential and Specific Regulator of Plasmacytoid Dendritic Cell Development

(2008) Babacar Cisse et al.   CELL

Granulocyte colony-stimulating factor: Molecular mechanisms of action during steady state and ‘emergency’ hematopoiesis

(2008) Athanasia D. Panopoulos et al.   CYTOKINE

Plasmacytoid Dendritic Cells Mediate Oral Tolerance

(2008) Anne Goubier et al.   IMMUNITY

The Signal Transducer STAT5 Inhibits Plasmacytoid Dendritic Cell Development by Suppressing Transcription Factor IRF8

(2008) Eiji Esashi et al.   IMMUNITY

Cytokine Signaling Modules in Inflammatory Responses

(2008) John J. O'Shea et al.   IMMUNITY

Differential expression of IRF8 in subsets of macrophages and dendritic cells and effects of IRF8 deficiency on splenic B cell and macrophage compartments

(2008) Chen-Feng Qi et al.   IMMUNOLOGIC RESEARCH

Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

(2008) Pingyan Cheng et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues

(2008) Claudia Waskow et al.   NATURE IMMUNOLOGY

Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

(2008) Karim C El Kasmi et al.   NATURE IMMUNOLOGY

Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

(2008) K. Hildner et al.   SCIENCE