The signaling pathway PI3K/Akt/Nrf2/HO-1 plays a role in the mitochondrial protection promoted by astaxanthin in the SH-SY5Y cells exposed to hydrogen peroxide

Protective Effect of Astaxanthin on Ochratoxin A-Induced Kidney Injury to Mice by Regulating Oxidative Stress-Related NRF2/KEAP1 Pathway

(2020) Lin Li et al.   MOLECULES

Neuroprotective effects of astaxanthin against oxygen and glucose deprivation damage via the PI3K/Akt/GSK3β/Nrf2 signalling pathway in vitro

(2020) Jie Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The Role of Mitochondria in Cardiovascular Diseases

(2020) Anastasia V. Poznyak et al.   Biology-Basel

Mitochondrial Reactive Oxygen Species: Double-Edged Weapon in Host Defense and Pathological Inflammation During Infection

(2020) Prashanta Silwal et al.   Frontiers in Immunology

Carvacrol Depends on Heme Oxygenase-1 (HO-1) to Exert Antioxidant, Anti-inflammatory, and Mitochondria-Related Protection in the Human Neuroblastoma SH-SY5Y Cells Line Exposed to Hydrogen Peroxide

(2019) Aline Lukasievicz Chenet et al.   NEUROCHEMICAL RESEARCH

Mitochondrial Oxidative Stress Impairs Energy Metabolism and Reduces Stress Resistance and Longevity of C. elegans

(2019) Benjamin Dilberger et al.   Oxidative Medicine and Cellular Longevity

Role of Catalase in Oxidative Stress- and Age-Associated Degenerative Diseases

(2019) Ankita Nandi et al.   Oxidative Medicine and Cellular Longevity

Anti-inflammatory effects of Aureusidin in LPS-stimulated RAW264.7 macrophages via suppressing NF-κB and activating ROS- and MAPKs-dependent Nrf2/HO-1 signaling pathways

(2019) Jie Ren et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The effects of kahweol, a diterpene present in coffee, on the mitochondria of the human neuroblastoma SH-SY5Y cells exposed to hydrogen peroxide

(2019) Cristina Ribas Fürstenau et al.   TOXICOLOGY IN VITRO

Acer okamotoanum protects SH-SY5Y neuronal cells against hydrogen peroxide-induced oxidative stress

(2018) Ji Hyun Kim et al.   FOOD SCIENCE AND BIOTECHNOLOGY

A review on heme oxygenase-1 induction: is it a necessary evil

(2018) Ajaz Ahmad Waza et al.   INFLAMMATION RESEARCH

Oxidative stress alters mitochondrial bioenergetics and modifies pancreatic cell death independently of cyclophilin D, resulting in an apoptosis-to-necrosis shift

(2018) Jane A. Armstrong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evaluation of the Mitochondria-Related Redox and Bioenergetics Effects of Gastrodin in SH-SY5Y Cells Exposed to Hydrogen Peroxide

(2018) Marcos Roberto de Oliveira et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Carnosic Acid as a Promising Agent in Protecting Mitochondria of Brain Cells

(2018) Marcos Roberto de Oliveira   MOLECULAR NEUROBIOLOGY

Naringenin Exerts Anti-inflammatory Effects in Paraquat-Treated SH-SY5Y Cells Through a Mechanism Associated with the Nrf2/HO-1 Axis

(2018) Marcos Roberto de Oliveira et al.   NEUROCHEMICAL RESEARCH

Sulforaphane Attenuated the Pro-Inflammatory State Induced by Hydrogen Peroxide in SH-SY5Y Cells Through the Nrf2/HO-1 Signaling Pathway

(2018) Marcos Roberto de Oliveira et al.   NEUROTOXICITY RESEARCH

Parkin clearance of dysfunctional mitochondria regulates ROS levels and increases survival of human chondrocytes

(2018) M.Y. Ansari et al.   OSTEOARTHRITIS AND CARTILAGE

Astaxanthin: A mechanistic review on its biological activities and health benefits

(2018) Sajad Fakhri et al.   PHARMACOLOGICAL RESEARCH

The anti-inflammatory effect of melatonin in SH-SY5Y neuroblastoma cells exposed to sublethal dose of hydrogen peroxide

(2017) Chutikorn Nopparat et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Resveratrol and Brain Mitochondria: a Review

(2017) Fernanda Rafaela Jardim et al.   MOLECULAR NEUROBIOLOGY

Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress

(2017) Helmut Sies   Redox Biology

Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism

(2016) Agnieszka Loboda et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Tanshinone I Attenuates the Effects of a Challenge with H2O2 on the Functions of Tricarboxylic Acid Cycle and Respiratory Chain in SH-SY5Y Cells

(2016) Marcos Roberto de Oliveira et al.   MOLECULAR NEUROBIOLOGY

Carnosic Acid Protects Mitochondria of Human Neuroblastoma SH-SY5Y Cells Exposed to Paraquat Through Activation of the Nrf2/HO-1Axis

(2016) Marcos Roberto de Oliveira et al.   MOLECULAR NEUROBIOLOGY

Cocaine and mitochondria-related signaling in the brain: A mechanistic view and future directions

(2016) Marcos Roberto de Oliveira et al.   NEUROCHEMISTRY INTERNATIONAL

Fluoxetine and the mitochondria: A review of the toxicological aspects

(2016) Marcos Roberto de Oliveira   TOXICOLOGY LETTERS

Role for the PI3K/Akt/Nrf2 signaling pathway in the protective effects of carnosic acid against methylglyoxal-induced neurotoxicity in SH-SY5Y neuroblastoma cells

(2015) Marcos Roberto de Oliveira et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The emerging role of Nrf2 in mitochondrial function

(2015) Albena T. Dinkova-Kostova et al.   FREE RADICAL BIOLOGY AND MEDICINE

Astaxanthin as a Potential Neuroprotective Agent for Neurological Diseases

(2015) Haijian Wu et al.   Marine Drugs

Inflammasome, mTORC1 activation, and metabolic derangement contribute to the susceptibility of diabetics to infections

(2015) Teresa Krakauer   MEDICAL HYPOTHESES

The Dietary Components Carnosic Acid and Carnosol as Neuroprotective Agents: a Mechanistic View

(2015) Marcos Roberto de Oliveira   MOLECULAR NEUROBIOLOGY

Biliverdin reductase isozymes in metabolism

(2015) Luke O’Brien et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Role of Metabolic H2O2Generation

(2014) Helmut Sies   JOURNAL OF BIOLOGICAL CHEMISTRY

Reactive oxygen species at the crossroads of inflammasome and inflammation

(2014) Anantha Harijith et al.   Frontiers in Physiology

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

Protective Effect of Paeoniflorin on Aβ25–35-Induced SH-SY5Y Cell Injury by Preventing Mitochondrial Dysfunction

(2013) Ke Wang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs

(2013) Takumi Satoh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Glutathione peroxidases

(2012) Regina Brigelius-Flohé et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Regulation of Nrf2-Mediated Phase II Detoxification and Anti-oxidant Genes

(2012) Young-Sam Keum   Biomolecules & Therapeutics

Mechanism of Oxidative Stress in Neurodegeneration

(2012) Sonia Gandhi et al.   Oxidative Medicine and Cellular Longevity

Direct Antioxidant Properties of Bilirubin and Biliverdin. Is there a Role for Biliverdin Reductase?

(2012) Thomas Jansen et al.   Frontiers in Pharmacology

H2O2

(2011) Margaret E. Rice   NEUROSCIENTIST

Mechanisms of Cell Protection by Heme Oxygenase-1

(2010) Raffaella Gozzelino et al.   Annual Review of Pharmacology and Toxicology

Astaxanthin upregulates heme oxygenase-1 expression through ERK1/2 pathway and its protective effect against beta-amyloid-induced cytotoxicity in SH-SY5Y cells

(2010) Hong-Quan Wang et al.   BRAIN RESEARCH

The sites and topology of mitochondrial superoxide production

(2010) Martin D. Brand   EXPERIMENTAL GERONTOLOGY

Conversion of biliverdin to bilirubin by biliverdin reductase contributes to endothelial cell protection by heme oxygenase-1—evidence for direct and indirect antioxidant actions of bilirubin

(2010) Thomas Jansen et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mitochondrial Dysfunction in Diabetes: From Molecular Mechanisms to Functional Significance and Therapeutic Opportunities

(2009) William I. Sivitz et al.   ANTIOXIDANTS & REDOX SIGNALING

Metallothionein-III protects against 6-hydroxydopamine-induced oxidative stress by increasing expression of heme oxygenase-1 in a PI3K and ERK/Nrf2-dependent manner

(2008) Y HWANG et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY