Mitochondrial Oxidative Stress Impairs Energy Metabolism and Reduces Stress Resistance and Longevity of C. elegans

Polyphenols and Metabolites Enhance Survival in Rodents and Nematodes—Impact of Mitochondria

(2019) Benjamin Dilberger et al.   Nutrients

Mitochondria-Mediated Pathway Regulates C2C12 Cell Apoptosis Induced by Fluoride

(2018) Pan-pan Tan et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Paraquat affects mitochondrial bioenergetics, dopamine system expression, and locomotor activity in zebrafish ( Danio rerio )

(2018) Xiao H. Wang et al.   CHEMOSPHERE

High-throughput BioSorter quantification of relative mitochondrial content and membrane potential in living Caenorhabditis elegans

(2018) Young Joon Kwon et al.   MITOCHONDRION

Metabolic effects of manganese in the nematode Caenorhabditis elegans through DAergic pathway and transcription factors activation

(2018) Priscila Gubert et al.   NEUROTOXICOLOGY

Enhanced ROS production leads to excessive fat accumulation through DAF-16 in Caenorhabditis elegans

(2018) Kejie Wang et al.   EXPERIMENTAL GERONTOLOGY

Mutation of hop-1 and pink-1 attenuates vulnerability of neurotoxicity in C. elegans: the role of mitochondria-associated membrane proteins in Parkinsonism

(2018) Siyu Wu et al.   EXPERIMENTAL NEUROLOGY

Impaired p53/CEP-1 is associated with lifespan extension through an age-related imbalance in the energy metabolism of C. elegans

(2017) Sumino Yanase et al.   GENES TO CELLS

Environmental conditions can modulate the links among oxidative stress, age, and longevity

(2017) Valeria Marasco et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Mitophagy Transcriptome: Mechanistic Insights into Polyphenol-Mediated Mitophagy

(2017) Sijie Tan et al.   Oxidative Medicine and Cellular Longevity

Oxidative Stress and Autophagy in Metabolism and Longevity

(2017) Ajit Vikram et al.   Oxidative Medicine and Cellular Longevity

Regulator of G protein signaling-1 modulates paraquat-induced oxidative stress and longevity via the insulin like signaling pathway in Caenorhabditis elegans

(2017) Mingyu Wu et al.   TOXICOLOGY LETTERS

Behavioral Phenotyping and Pathological Indicators of Parkinson's Disease in C. elegans Models

(2017) Malabika Maulik et al.   Frontiers in Genetics

Slm35 links mitochondrial stress response and longevity through TOR signaling pathway

(2016) Jose L. Aguilar-Lopez et al.   Aging-US

Identification and Characterization of Mitochondrial Subtypes in Caenorhabditis elegans via Analysis of Individual Mitochondria by Flow Cytometry

(2016) Joseph R. Daniele et al.   ANALYTICAL CHEMISTRY

In Vivo Detection of Reactive Oxygen Species and Redox Status in Caenorhabditis elegans

(2016) Bart P. Braeckman et al.   ANTIOXIDANTS & REDOX SIGNALING

Antioxidant and neuroprotective effects of Dictyophora indusiata polysaccharide in Caenorhabditis elegans

(2016) Ju Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Caenorhabditis elegans: What We Can and Cannot Learn from Aging Worms

(2015) Jan Gruber et al.   ANTIOXIDANTS & REDOX SIGNALING

Lifespan extension and increased resistance to environmental stressors by N-Acetyl-L-Cysteine in Caenorhabditis elegans

(2015) SI Oh et al.   Clinics

Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans

(2015) Konstantinos Palikaras et al.   NATURE

The metabolic regulation of aging

(2015) Toren Finkel   NATURE MEDICINE

Mitochondrial dysfunction and longevity in animals: Untangling the knot

(2015) Y. Wang et al.   SCIENCE

Mitochondrial and Cytoplasmic ROS Have Opposing Effects on Lifespan

(2015) Claire E. Schaar et al.   PLoS Genetics

Alterations in Energy/Redox Metabolism Induced by Mitochondrial and Environmental Toxins: A Specific Role for Glucose-6-Phosphate-Dehydrogenase and the Pentose Phosphate Pathway in Paraquat Toxicity

(2014) Shulei Lei et al.   ACS Chemical Biology

Endogenous ROS levels in C. elegans under exogenous stress support revision of oxidative stress theory of life-history tradeoffs

(2014) Samson W Smith et al.   BMC EVOLUTIONARY BIOLOGY

AMPK at the Nexus of Energetics and Aging

(2014) Kristopher Burkewitz et al.   Cell Metabolism

Mitochondrial efficiency is increased in axenically cultured Caenorhabditis elegans

(2014) Natascha Castelein et al.   EXPERIMENTAL GERONTOLOGY

Mitochondrial stress extends lifespan in C. elegans through neuronal hormesis

(2014) Silvia Maglioni et al.   EXPERIMENTAL GERONTOLOGY

The C. elegans lifespan assay toolkit

(2014) Francis Raj Gandhi Amrit et al.   METHODS

The polyphenol quercetin protects themev-1mutant ofCaenorhabditis elegansfrom glucose-induced reduction of survival under heat-stress depending on SIR-2.1, DAF-12, and proteasomal activity

(2014) Elena Fitzenberger et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Mitochondrial form and function

(2014) Jonathan R. Friedman et al.   NATURE

Effects of Plant Extracts on the Reversal of Glucose-Induced Impairment of Stress-Resistance in Caenorhabditis elegans

(2014) Elena Fitzenberger et al.   PLANT FOODS FOR HUMAN NUTRITION

Feedback regulation via AMPK and HIF-1 mediates ROS-dependent longevity inCaenorhabditis elegans

(2014) Ara B. Hwang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ilex paraguariensis Extract Increases Lifespan and Protects Against the Toxic Effects Caused by Paraquat in Caenorhabditis elegans

(2014) Maria Lima et al.   International Journal of Environmental Research and Public Health

Mitochondrial hormesis links low-dose arsenite exposure to lifespan extension

(2013) Sebastian Schmeisser et al.   AGING CELL

A semi-automated method for isolating functionally intact mitochondria from cultured cells and tissue biopsies

(2013) Sabine Schmitt et al.   ANALYTICAL BIOCHEMISTRY

Rice bran extract protects from mitochondrial dysfunction in guinea pig brains

(2013) Stephanie Hagl et al.   PHARMACOLOGICAL RESEARCH

Biomarkers of mitochondrial content in skeletal muscle of healthy young human subjects

(2012) Steen Larsen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mitochondrial Import Efficiency of ATFS-1 Regulates Mitochondrial UPR Activation

(2012) A. M. Nargund et al.   SCIENCE

Breaking Caenorhabditis elegans the easy way using the Balch homogenizer: An old tool for a new application

(2011) Shylesh Bhaskaran et al.   ANALYTICAL BIOCHEMISTRY

The Homeobox Protein CEH-23 Mediates Prolonged Longevity in Response to Impaired Mitochondrial Electron Transport Chain in C. elegans

(2011) Ludivine Walter et al.   PLOS BIOLOGY

Cellular Stress Responses, The Hormesis Paradigm, and Vitagenes: Novel Targets for Therapeutic Intervention in Neurodegenerative Disorders

(2010) Vittorio Calabrese et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial longevity pathways

(2010) Anna Raffaello et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

New insights into the role of mitochondria in aging: mitochondrial dynamics and more

(2010) A. Y. Seo et al.   JOURNAL OF CELL SCIENCE

Regional Anatomic Differences in Skeletal Muscle Mitochondrial Respiration in Type 2 Diabetes and Obesity

(2010) R. Rabøl et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

A Mitochondrial Superoxide Signal Triggers Increased Longevity in Caenorhabditis elegans

(2010) Wen Yang et al.   PLOS BIOLOGY

p53/CEP-1 increases or decreases lifespan, depending on level of mitochondrial bioenergetic stress

(2009) Natascia Ventura et al.   AGING CELL

Caenorhabditis elegans lifespan extension caused by treatment with an orally active ROS-generator is dependent on DAF-16 and SIR-2.1

(2009) Tanja Heidler et al.   BIOGERONTOLOGY

Extension of Drosophila Life Span by RNAi of the Mitochondrial Respiratory Chain

(2009) Jeffrey M. Copeland et al.   CURRENT BIOLOGY