SpaceM reveals metabolic states of single cells

In Vivo Subcellular Mass Spectrometry Enables Proteo‐Metabolomic Single‐cell Systems Biology in a Chordate Embryo Developing to a Normally Behaving Tadpole (X. laevis)

(2021) Camille Lombard-Banek et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

OffsampleAI: artificial intelligence approach to recognize off-sample mass spectrometry images

(2020) Katja Ovchinnikova et al.   BMC BIOINFORMATICS

Benchmarking single-cell RNA-sequencing protocols for cell atlas projects

(2020) Elisabetta Mereu et al.   NATURE BIOTECHNOLOGY

An atlas of human metabolism

(2020) Jonathan L. Robinson et al.   Science Signaling

Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma

(2020) Allison N Lau et al.   eLife

Single-cell metabolomics by mass spectrometry: Advances, challenges, and future applications

(2019) Ahmed Ali et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Metabolic Imaging at the Single-Cell Scale: Recent Advances in Mass Spectrometry Imaging

(2019) Ian S. Gilmore et al.   Annual Review of Analytical Chemistry

Lipid Heterogeneity between Astrocytes and Neurons Revealed by Single-Cell MALDI-MS Combined with Immunocytochemical Classification

(2019) Elizabeth K. Neumann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rapid, Untargeted Chemical Profiling of Single Cells in Their Native Environment

(2019) John F. Cahill et al.   ANALYTICAL CHEMISTRY

The landscape of cancer cell line metabolism

(2019) Haoxin Li et al.   NATURE MEDICINE

Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer

(2019) Mohsen Malehmir et al.   NATURE MEDICINE

From NASH to HCC: current concepts and future challenges

(2019) Quentin M. Anstee et al.   Nature Reviews Gastroenterology & Hepatology

LION/web: a web-based ontology enrichment tool for lipidomic data analysis

(2019) Martijn R Molenaar et al.   GigaScience

A human liver cell atlas reveals heterogeneity and epithelial progenitors

(2019) Nadim Aizarani et al.   NATURE

Mechanisms and Implications of Metabolic Heterogeneity in Cancer

(2019) Jiyeon Kim et al.   Cell Metabolism

Single-Cell Mass Spectrometry Approaches to Explore Cellular Heterogeneity

(2018) Linwen Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Specific Hepatic Sphingolipids Relate to Insulin Resistance, Oxidative Stress, and Inflammation in Nonalcoholic Steatohepatitis

(2018) Maria Apostolopoulou et al.   DIABETES CARE

Regulation of Drug Metabolism by the Interplay of Inflammatory Signaling, Steatosis, and Xeno-Sensing Receptors in HepaRG Cells

(2018) Norman Tanner et al.   DRUG METABOLISM AND DISPOSITION

Extreme heterogeneity of influenza virus infection in single cells

(2018) Alistair B Russell et al.   eLife

T-Probe: An Integrated Microscale Device for Online In Situ Single Cell Analysis and Metabolic Profiling Using Mass Spectrometry

(2018) Renmeng Liu et al.   ANALYTICAL CHEMISTRY

Targeting a phospho-STAT3-miRNAs pathway improves vesicular hepatic steatosis in an in vitro and in vivo model

(2018) Laura Belloni et al.   Scientific Reports

Advanced Registration and Analysis of MALDI Imaging Mass Spectrometry Measurements through Autofluorescence Microscopy

(2018) Nathan Heath Patterson et al.   ANALYTICAL CHEMISTRY

Lipid zonation and phospholipid remodeling in nonalcoholic fatty liver disease

(2017) Zoe Hall et al.   HEPATOLOGY

microMS: A Python Platform for Image-Guided Mass Spectrometry Profiling

(2017) Troy J. Comi et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Interplay between metabolic identities in the intestinal crypt supports stem cell function

(2017) Maria J. Rodríguez-Colman et al.   NATURE

Lipid droplets and liver disease: from basic biology to clinical implications

(2017) Nina L. Gluchowski et al.   Nature Reviews Gastroenterology & Hepatology

Tunable Single-Cell Extraction for Molecular Analyses

(2016) Orane Guillaume-Gentil et al.   CELL

FDR-controlled metabolite annotation for high-resolution imaging mass spectrometry

(2016) Andrew Palmer et al.   NATURE METHODS

Endoplasmic reticulum proteostasis in hepatic steatosis

(2016) Andrei Baiceanu et al.   Nature Reviews Endocrinology

Metabolomics: beyond biomarkers and towards mechanisms

(2016) Caroline H. Johnson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Laser dissection sampling modes for direct mass spectral analysis

(2016) John F. Cahill et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Mechanisms of intrahepatic triglyceride accumulation

(2016) Claudia Ress   WORLD JOURNAL OF GASTROENTEROLOGY

Self-renewing diploid Axin2+ cells fuel homeostatic renewal of the liver

(2015) Bruce Wang et al.   NATURE

Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors

(2015) Anneleen Daemen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of hepatic lipid profiles in a mouse model with nonalcoholic steatohepatitis and subsequent fibrosis

(2015) Kosuke Saito et al.   Scientific Reports

Metabolic Activation of Intrahepatic CD8+ T Cells and NKT Cells Causes Nonalcoholic Steatohepatitis and Liver Cancer via Cross-Talk with Hepatocytes

(2014) Monika Julia Wolf et al.   CANCER CELL

Single-cell analyses of transcriptional heterogeneity during drug tolerance transition in cancer cells by RNA sequencing

(2014) M.-C. W. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-to-Cell Heterogeneity in Lipid Droplets Suggests a Mechanism to Reduce Lipotoxicity

(2013) Albert Herms et al.   CURRENT BIOLOGY

Mass spectrometry-based metabolomics of single yeast cells

(2013) A. J. Ibanez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-Cell Metabolomics: Analytical and Biological Perspectives

(2013) R. Zenobi   SCIENCE

Progress toward single cell metabolomics

(2012) Stanislav S Rubakhin et al.   CURRENT OPINION IN BIOTECHNOLOGY

A two-way street: reciprocal regulation of metabolism and signalling

(2012) Kathryn E. Wellen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Using Cell-to-Cell Variability--A New Era in Molecular Biology

(2012) L. Pelkmans   SCIENCE

Profiling metabolites and peptides in single cells

(2011) Stanislav S Rubakhin et al.   NATURE METHODS

Globally optimal stitching of tiled 3D microscopic image acquisitions

(2009) S. Preibisch et al.   BIOINFORMATICS

Live Cell Multicolor Imaging of Lipid Droplets with a New Dye, LD540

(2009) Johanna Spandl et al.   TRAFFIC