Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer

The Platelet Lifeline to Cancer: Challenges and Opportunities

(2018) Monika Haemmerle et al.   CANCER CELL

Cited4 is a sex‐biased mediator of the antidiabetic glitazone response in adipocyte progenitors

(2018) Irem Bayindir‐Buchhalter et al.   EMBO Molecular Medicine

The immunology of hepatocellular carcinoma

(2018) Marc Ringelhan et al.   NATURE IMMUNOLOGY

Mechanisms of NAFLD development and therapeutic strategies

(2018) Scott L. Friedman et al.   NATURE MEDICINE

Global Perspectives on Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis

(2018) Zobair Younossi et al.   HEPATOLOGY

Current Concepts in Pediatric Nonalcoholic Fatty Liver Disease

(2017) Sarah E. Fleet et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Increased risk of mortality by fibrosis stage in nonalcoholic fatty liver disease: Systematic review and meta-analysis

(2017) Parambir S. Dulai et al.   HEPATOLOGY

Thrombin promotes diet-induced obesity through fibrin-driven inflammation

(2017) Anna K. Kopec et al.   JOURNAL OF CLINICAL INVESTIGATION

β 7 -Integrin and MAdCAM-1 play opposing roles during the development of non-alcoholic steatohepatitis

(2017) Hannah K. Drescher et al.   JOURNAL OF HEPATOLOGY

Antithrombotic therapy for patients with STEMI undergoing primary PCI

(2017) Francesco Franchi et al.   Nature Reviews Cardiology

Health Effects of Overweight and Obesity in 195 Countries over 25 Years

(2017)   NEW ENGLAND JOURNAL OF MEDICINE

A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis

(2017) Sebastian Dütting et al.   Nature Communications

Non-alcoholic fatty liver disease in 2016

(2016) S.A. Townsend et al.   BRITISH MEDICAL BULLETIN

Metabolic Inflammation-Associated IL-17A Causes Non-alcoholic Steatohepatitis and Hepatocellular Carcinoma

(2016) Ana L. Gomes et al.   CANCER CELL

Intestinal Phospholipid Remodeling Is Required for Dietary-Lipid Uptake and Survival on a High-Fat Diet

(2016) Bo Wang et al.   Cell Metabolism

Platelets: No longer bystanders in liver disease

(2016) Abhishek Chauhan et al.   HEPATOLOGY

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

Platelet Interaction with Innate Immune Cells

(2016) Julia Barbara Kral et al.   TRANSFUSION MEDICINE AND HEMOTHERAPY

The impact of amplification on differential expression analyses by RNA-seq

(2016) Swati Parekh et al.   Scientific Reports

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease

(2015) Paul Angulo et al.   GASTROENTEROLOGY

Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial

(2015) Brent A Neuschwander-Tetri et al.   LANCET

Nonalcoholic fatty liver disease

(2015) Elizabeth M. Brunt et al.   Nature Reviews Disease Primers

All-In-One: Advanced preparation of Human Parenchymal and Non-Parenchymal Liver Cells

(2015) Melanie Werner et al.   PLoS One

Association between aspirin use and the prevalence of nonalcoholic fatty liver disease: a cross-sectional study from the Third National Health and Nutrition Examination Survey

(2014) H. Shen et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Metabolic Activation of Intrahepatic CD8+ T Cells and NKT Cells Causes Nonalcoholic Steatohepatitis and Liver Cancer via Cross-Talk with Hepatocytes

(2014) Monika Julia Wolf et al.   CANCER CELL

Epidemiology of hepatocellular carcinoma in the United States: Where are we? Where do we go?

(2014) Hashem B. El-Serag et al.   HEPATOLOGY

Structural Basis of Regulation of von Willebrand Factor Binding to Glycoprotein Ib

(2014) Mark A. Blenner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis

(2014) Chris J. Weston et al.   JOURNAL OF CLINICAL INVESTIGATION

Twelve or 30 Months of Dual Antiplatelet Therapy after Drug-Eluting Stents

(2014) Laura Mauri et al.   NEW ENGLAND JOURNAL OF MEDICINE

Diet-induced mouse model of fatty liver disease and nonalcoholic steatohepatitis reflecting clinical disease progression and methods of assessment

(2013) Jason R. Clapper et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice

(2013) Carsten Deppermann et al.   JOURNAL OF CLINICAL INVESTIGATION

Effect of echo-sampling strategy on the accuracy of out-of-phase and in-phase multiecho gradient-Echo MRI hepatic fat fraction estimation

(2013) Yakir S. Levin et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Quantitative imaging of haematopoietic stem and progenitor cell localization and hypoxic status in the bone marrow microenvironment

(2013) César Nombela-Arrieta et al.   NATURE CELL BIOLOGY

Does size matter in platelet production?

(2012) J. N. Thon et al.   BLOOD

Increased Hepatic Synthesis and Dysregulation of Cholesterol Metabolism Is Associated with the Severity of Nonalcoholic Fatty Liver Disease

(2012) Hae-Ki Min et al.   Cell Metabolism

Platelets Contribute to the Pathogenesis of Experimental Autoimmune Encephalomyelitis

(2012) Harald F. Langer et al.   CIRCULATION RESEARCH

Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of randomised trials

(2012) G. Musso et al.   DIABETOLOGIA

Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B

(2012) G. Sitia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IκB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-κB in the central nervous system

(2011) Jenni Raasch et al.   BRAIN

Genetic and antibody-induced glycoprotein VI deficiency equally protects mice from mechanically and FeCl3-induced thrombosis

(2011) M. BENDER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Mutations in NBEAL2, encoding a BEACH protein, cause gray platelet syndrome

(2011) Walter HA Kahr et al.   NATURE GENETICS

Exome sequencing identifies NBEAL2 as the causative gene for gray platelet syndrome

(2011) Cornelis A Albers et al.   NATURE GENETICS

NBEAL2 is mutated in gray platelet syndrome and is required for biogenesis of platelet α-granules

(2011) Meral Gunay-Aygun et al.   NATURE GENETICS

Arterial thrombosis—insidious, unpredictable and deadly

(2011) Shaun P Jackson   NATURE MEDICINE

NF-κB and STAT3 – key players in liver inflammation and cancer

(2010) Guobin He et al.   CELL RESEARCH

CLEC-2 is an essential platelet-activating receptor in hemostasis and thrombosis

(2009) F. May et al.   BLOOD

Ticagrelor: The First Reversibly Binding Oral P2Y12Receptor Antagonist

(2009) Steen Husted et al.   Cardiovascular Therapeutics

Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes

(2009) Lars Wallentin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effectiveness of antiplatelet drugs against experimental non-alcoholic fatty liver disease

(2008) K Fujita et al.   GUT

Aggravation of viral hepatitis by platelet-derived serotonin

(2008) Philipp A Lang et al.   NATURE MEDICINE