Self-tunable engineered yeast probiotics for the treatment of inflammatory bowel disease
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Title
Self-tunable engineered yeast probiotics for the treatment of inflammatory bowel disease
Authors
Keywords
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Journal
NATURE MEDICINE
Volume 27, Issue 7, Pages 1212-1222
Publisher
Springer Science and Business Media LLC
Online
2021-06-29
DOI
10.1038/s41591-021-01390-x
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- (2017) INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
- Molecular Recognition of Agonists and Antagonists by the Nucleotide-Activated G Protein-Coupled P2Y2 Receptor
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- (2015) Sergey V. Prykhozhij et al. PLoS One
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