“Off-Spotter”: very fast and exhaustive enumeration of genomic lookalikes for designing CRISPR/Cas guide RNAs
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
“Off-Spotter”: very fast and exhaustive enumeration of genomic lookalikes for designing CRISPR/Cas guide RNAs
Authors
Keywords
CRISPR, Off-targets, Cas endonucleases, Cas9, Guide RNAs, gRNAs, Indexing, Hashing
Journal
Biology Direct
Volume 10, Issue 1, Pages 4
Publisher
Springer Nature
Online
2015-01-29
DOI
10.1186/s13062-015-0035-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases
- (2014) S. Bae et al. BIOINFORMATICS
- Gene regulation by engineered CRISPR-Cas systems
- (2014) Peter C Fineran et al. CURRENT OPINION IN MICROBIOLOGY
- A New World Order: Tailored Gene Targeting and Regulation Using CRISPR
- (2014) Marc S Weinberg et al. MOLECULAR THERAPY
- Group size and cultural complexity
- (2014) Claes Andersson et al. NATURE
- Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells
- (2014) Xuebing Wu et al. NATURE BIOTECHNOLOGY
- Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
- (2014) Yanfang Fu et al. NATURE BIOTECHNOLOGY
- Rational design of highly active sgRNAs for CRISPR-Cas9–mediated gene inactivation
- (2014) John G Doench et al. NATURE BIOTECHNOLOGY
- CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing
- (2014) Tessa G. Montague et al. NUCLEIC ACIDS RESEARCH
- sgRNAcas9: A Software Package for Designing CRISPR sgRNA and Evaluating Potential Off-Target Cleavage Sites
- (2014) Shengsong Xie et al. PLoS One
- CRISPRseek: A Bioconductor Package to Identify Target-Specific Guide RNAs for CRISPR-Cas9 Genome-Editing Systems
- (2014) Lihua J. Zhu et al. PLoS One
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- Ensembl 2014
- (2013) Paul Flicek et al. NUCLEIC ACIDS RESEARCH
- Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis
- (2013) Z. Hou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The CRISPR Craze
- (2013) E. Pennisi SCIENCE
- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus
- (2013) Hirotaka Ebina et al. Scientific Reports
- RNA-guided genetic silencing systems in bacteria and archaea
- (2012) Blake Wiedenheft et al. NATURE
- Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
- (2012) G. Gasiunas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
- (2012) M. Jinek et al. SCIENCE
- RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions
- (2011) B. Wiedenheft et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence
- (2011) E. Semenova et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CRISPR/Cas System and Its Role in Phage-Bacteria Interactions
- (2010) Hélène Deveau et al. Annual Review of Microbiology
- Short RNAs: How Big Is This Iceberg?
- (2010) Isidore Rigoutsos CURRENT BIOLOGY
- CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea
- (2010) Luciano A. Marraffini et al. NATURE REVIEWS GENETICS
- New Tricks for Animal MicroRNAs: Targeting of Amino Acid Coding Regions at Conserved and Nonconserved Sites
- (2009) I. Rigoutsos CANCER RESEARCH
- Short motif sequences determine the targets of the prokaryotic CRISPR defence system
- (2009) MICROBIOLOGY-SGM
- Alu and B1 Repeats Have Been Selectively Retained in the Upstream and Intronic Regions of Genes of Specific Functional Classes
- (2009) Aristotelis Tsirigos et al. PLoS Computational Biology
- Human and mouse introns are linked to the same processes and functions through each genome's most frequent non-conserved motifs
- (2008) Aristotelis Tsirigos et al. NUCLEIC ACIDS RESEARCH
- Small CRISPR RNAs Guide Antiviral Defense in Prokaryotes
- (2008) S. J. J. Brouns et al. SCIENCE
- CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA
- (2008) Luciano A. Marraffini et al. SCIENCE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started