Antiviral Activity of Carrageenans and Processing Implications

Antiviral activity of lambda-carrageenan against influenza viruses and severe acute respiratory syndrome coronavirus 2

(2021) Yejin Jang et al.   Scientific Reports

Carrageenan containing over-the-counter nasal and oral sprays inhibit SARS-CoV-2 infection of airway epithelial cultures

(2021) Desiree Schütz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Antiviral Potential of Algal Metabolites—A Comprehensive Review

(2021) António Pagarete et al.   Marine Drugs

Iota-carrageenan neutralizes SARS-CoV-2 and inhibits viral replication in vitro

(2021) Martina Morokutti-Kurz et al.   PLoS One

Insight on structure-property relationships of carrageenan from marine red algal: A review

(2021) Jia-Li Jiang et al.   CARBOHYDRATE POLYMERS

Formulation of a Composite Nasal Spray Enabling Enhanced Surface Coverage and Prophylaxis of SARS‐COV‐2

(2021) Richard J. A. Moakes et al.   ADVANCED MATERIALS

Marine sulfated polysaccharides as potential antiviral drug candidates to treat Corona Virus disease (COVID-19)

(2021) Monic Andrew et al.   CARBOHYDRATE RESEARCH

Eco-friendly extraction of Mastocarpus stellatus carrageenan for the synthesis of gold nanoparticles with improved biological activity

(2021) N. González-Ballesteros et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Prophylactic antiviral activity of sulfated glycomimetic oligomers and polymers

(2020) Laura Soria-Martinez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Investigation on bio-properties and in-vivo antioxidant potential of carrageenans against alloxan induced oxidative stress in Wistar albino rats

(2020) Muthusamy Sanjivkumar et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

The COVID 19 novel coronavirus pandemic 2020: seaweeds to the rescue? Why does substantial, supporting research about the antiviral properties of seaweed polysaccharides seem to go unrecognized by the pharmaceutical community in these desperate times?

(2020) Leonel Pereira et al.   JOURNAL OF APPLIED PHYCOLOGY

Marine Algal Antioxidants as Potential Vectors for Controlling Viral Diseases

(2020) Clementina Sansone et al.   Antioxidants

The style and substance of plant flavonoid decoration; towards defining both structure and function

(2020) Saleh Alseekh et al.   PHYTOCHEMISTRY

Marine‐polysaccharide degrading enzymes: Status and prospects

(2020) Huihui Sun et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Carrageenans as Broad-Spectrum Microbicides: Current Status and Challenges

(2020) Choongho Lee   Marine Drugs

The Potential of Algal Biotechnology to Produce Antiviral Compounds and Biopharmaceuticals

(2020) Sergio Rosales-Mendoza et al.   MOLECULES

Therapeutic Uses of Red Macroalgae

(2020) Mona M. Ismail et al.   MOLECULES

Antibody-independent and dependent infection of human myeloid cells with dengue virus is inhibited by carrageenan

(2020) Luana E. Piccini et al.   VIRUS RESEARCH

The microwave assisted extraction sway on the features of antioxidant compounds and gelling biopolymers from Mastocarpus stellatus

(2020) E. Ponthier et al.   Algal Research-Biomass Biofuels and Bioproducts

Microwave-assisted depolymerization of carrageenans from Kappaphycus alvarezii and Eucheuma spinosum: Controlled and green production of oligosaccharides from the algae biomass

(2020) Tiffani Bouanati et al.   Algal Research-Biomass Biofuels and Bioproducts

Structural Diversity in Galactans From Red Seaweeds and Its Influence on Rheological Properties

(2020) Marina Ciancia et al.   Frontiers in Plant Science

Application prospect of polysaccharides in the development of anti-novel coronavirus drugs and vaccines

(2020) Xiangyan Chen et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Anti-Herpes simplex virus (HSV-1) activity and antioxidant capacity of carrageenan-rich enzymatic extracts from Solieria filiformis (Gigartinales, Rhodophyta)

(2020) Peñuela Ana et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Carrageenan: Drug Delivery Systems and Other Biomedical Applications

(2020) Edisson-Mauricio Pacheco-Quito et al.   Marine Drugs

Carrageenan: A Wonder Polymer from Marine Algae for Potential Drug Delivery Applications

(2019) Dilshad Qureshia et al.   CURRENT PHARMACEUTICAL DESIGN

Integral Utilization of Red Seaweed for Bioactive Production

(2019) Torres et al.   Marine Drugs

Marine glycan–based antiviral agents in clinical or preclinical trials

(2019) Cui Hao et al.   REVIEWS IN MEDICAL VIROLOGY

On the use of carrageenan matrices for the development of antiviral edible coatings of interest in berries

(2019) Irene Falcó et al.   FOOD HYDROCOLLOIDS

Chemically modified polysaccharides: Synthesis, characterization, structure activity relationships of action

(2019) Yong Xu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Marine Algae Metabolites as Promising Therapeutics for the Prevention and Treatment of HIV/AIDS

(2019) Natalya N. Besednova et al.   Metabolites

Antiviral bioactivity of renewable polysaccharides against Varicella Zoster

(2019) Eiman Abu-Galiyun et al.   CELL CYCLE

Successful Approaches for a Red Seaweed Biorefinery

(2019) Álvarez-Viñas et al.   Marine Drugs

A review of extractions of seaweed hydrocolloids: Properties and applications

(2018) H. P. S. Abdul Khalil et al.   Express Polymer Letters

Impact of counterions on the thermo-rheological features of hybrid carrageenan systems isolated from red seaweed Gigartina skottsbergii

(2018) M.D. Torres et al.   FOOD HYDROCOLLOIDS

The antiviral activity of polysaccharides and their derivatives

(2018) Ling Chen et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Carrageenans and carrageenases: versatile polysaccharides and promising marine enzymes

(2018) Mehri Ghanbarzadeh et al.   PHYTOCHEMISTRY REVIEWS

Recovery of carrageenan from Solomon Islands red seaweed using ionic liquid-assisted subcritical water extraction

(2018) Collin Rudolf Nobbs Gereniu et al.   SEPARATION AND PURIFICATION TECHNOLOGY

Oligosaccharides Derived from Red Seaweed: Production, Properties, and Potential Health and Cosmetic Applications

(2018) Kit-Leong Cheong et al.   MOLECULES

Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPV infections in vivo

(2018) Nina Derby et al.   Nature Communications

Environmentally Friendly Valorization of Solieria filiformis (Gigartinales, Rhodophyta) from IMTA Using a Biorefinery Concept

(2018) Ana Peñuela et al.   Marine Drugs

Antiherpetic (HSV-1) activity of carrageenans from the red seaweed Solieria chordalis (Rhodophyta, Gigartinales) extracted by microwave-assisted extraction (MAE)

(2017) Romain Boulho et al.   JOURNAL OF APPLIED PHYCOLOGY

Degradation of Polysaccharides from Grateloupia filicina and Their Antiviral Activity to Avian Leucosis Virus Subgroup J

(2017) Yuhao Sun et al.   Marine Drugs

An intravaginal ring that releases three antiviral agents and a contraceptive blocks SHIV-RT infection, reduces HSV-2 shedding, and suppresses hormonal cycling in rhesus macaques

(2017) Nina Derby et al.   Drug Delivery and Translational Research

Glycan–protein interactions in viral pathogenesis

(2016) Rahul Raman et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Parameters and pitfalls to consider in the conduct of food additive research, Carrageenan as a case study

(2016) Myra L. Weiner   FOOD AND CHEMICAL TOXICOLOGY

Effects of lambda-carrageenan on equid herpesvirus 3 in vitro

(2016) M.A. Vissani et al.   JOURNAL OF EQUINE VETERINARY SCIENCE

Characterization of in vitro dengue virus resistance to carrageenan

(2016) Laura B. Talarico et al.   JOURNAL OF MEDICAL VIROLOGY

Inhibition of Human Metapneumovirus Binding to Heparan Sulfate Blocks Infection in Human Lung Cells and Airway Tissues

(2016) Edita M. Klimyte et al.   JOURNAL OF VIROLOGY

The Experimental Research (In Vitro) of Carrageenans and Fucoidans to Decrease Activity of Hantavirus

(2016) Stanislav N. Pavliga et al.   Food and Environmental Virology

Griffithsin and Carrageenan Combination To Target Herpes Simplex Virus 2 and Human Papillomavirus

(2015) Keith Levendosky et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Partial and total C-6 oxidation of gelling carrageenans. Modulation of the antiviral activity with the anionic character

(2015) Vanina A. Cosenza et al.   CARBOHYDRATE POLYMERS

An infant formula toxicity and toxicokinetic feeding study on carrageenan in preweaning piglets with special attention to the immune system and gastrointestinal tract

(2015) M.L. Weiner et al.   FOOD AND CHEMICAL TOXICOLOGY

Effect of pre-extraction alkali treatment on the chemical structure and gelling properties of extracted hybrid carrageenan from Chondrus crispus and Ahnfeltiopsis devoniensis

(2015) G. Azevedo et al.   FOOD HYDROCOLLOIDS

BAHD or SCPL acyltransferase? What a dilemma for acylation in the world of plant phenolic compounds

(2015) Thibaut Bontpart et al.   NEW PHYTOLOGIST

λ-Carrageenan P32 Is a Potent Inhibitor of Rabies Virus Infection

(2015) Zhaochen Luo et al.   PLoS One

Antiviral activity of lambda-carrageenan prepared from red seaweed (Gigartina skottsbergii) against BoHV-1 and SuHV-1

(2015) Jésica V. Diogo et al.   RESEARCH IN VETERINARY SCIENCE

Antitumor and Adjuvant Activity of λ-carrageenan by Stimulating Immune Response in Cancer Immunotherapy

(2015) Min Luo et al.   Scientific Reports

Antiviral Potential of Algae Polysaccharides Isolated from Marine Sources: A Review

(2015) Azin Ahmadi et al.   Biomed Research International

Specific Inhibitory Effect of κ-Carrageenan Polysaccharide on Swine Pandemic 2009 H1N1 Influenza Virus

(2015) Qiang Shao et al.   PLoS One

Non-Clinical Safety Evaluation of Intranasal Iota-Carrageenan

(2015) Alexandra Hebar et al.   PLoS One

The Intranasal Application of Zanamivir and Carrageenan Is Synergistically Active against Influenza A Virus in the Murine Model

(2015) Martina Morokutti-Kurz et al.   PLoS One

Crystal structure of the human glucose transporter GLUT1

(2014) Dong Deng et al.   NATURE

A Potent Combination Microbicide that Targets SHIV-RT, HSV-2 and HPV

(2014) Larisa Kizima et al.   PLoS One

Carrageenan nasal spray in virus confirmed common cold: individual patient data analysis of two randomized controlled trials

(2014) Martin Koenighofer et al.   MULTIDISCIPLINARY RESPIRATORY MEDICINE

Antioxidant activity potential of gamma irradiated carrageenan

(2013) Lucille V. Abad et al.   APPLIED RADIATION AND ISOTOPES

Structure and anti-metapneumovirus activity of sulfated galactans from the red seaweed Cryptonemia seminervis

(2013) Gabriella S. Mendes et al.   CARBOHYDRATE POLYMERS

Enzymatic preparation of κ-carrageenan oligosaccharides and their anti-angiogenic activity

(2013) Ziang Yao et al.   CARBOHYDRATE POLYMERS

Sulfated polysaccharides as bioactive agents from marine algae

(2013) Dai-Hung Ngo et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Efficacy of a Carrageenan nasal spray in patients with common cold: a randomized controlled trial

(2013) Martin Ludwig et al.   RESPIRATORY RESEARCH

Prevention of human enterovirus 71 infection by kappa carrageenan

(2012) Ya-Huang Chiu et al.   ANTIVIRAL RESEARCH

Lessons learned from a double-blind randomised placebo-controlled study with a iota-carrageenan nasal spray as medical device in children with acute symptoms of common cold

(2012) Tamas Fazekas et al.   BMC Complementary and Alternative Medicine

Preparation and anti-influenza A virus activity of κ-carrageenan oligosaccharide and its sulphated derivatives

(2012) Wei Wang et al.   FOOD CHEMISTRY

Low molecular weight derivatives of different carrageenan types and their antiviral activity

(2012) A. A. Kalitnik et al.   JOURNAL OF APPLIED PHYCOLOGY

Preparation and potentialin vivoanti-influenza virus activity of low molecular-weight κ-carrageenans and their derivatives

(2012) Fengxiang Tang et al.   JOURNAL OF APPLIED POLYMER SCIENCE

The Antiviral Activities and Mechanisms of Marine Polysaccharides: An Overview

(2012) Wei Wang et al.   Marine Drugs

Zinc Acetate/Carrageenan Gels Exhibit Potent ActivityIn Vivoagainst High-Dose Herpes Simplex Virus 2 Vaginal and Rectal Challenge

(2011) José A. Fernández-Romero et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In vitro inhibitory effect of carrageenan oligosaccharide on influenza A H1N1 virus

(2011) Wei Wang et al.   ANTIVIRAL RESEARCH

In vitro inhibition of influenza A virus infection by marine microalga-derived sulfated polysaccharide p-KG03

(2011) Meehyein Kim et al.   ANTIVIRAL RESEARCH

The effectiveness of Carraguard, a vaginal microbicide, in protecting women against high-risk human papillomavirus infection

(2011) Dianne Marais et al.   ANTIVIRAL THERAPY

Differential inhibition of dengue virus infection in mammalian and mosquito cells by iota-carrageenan

(2011) L. B. Talarico et al.   JOURNAL OF GENERAL VIROLOGY

Chemical Structures and Bioactivities of Sulfated Polysaccharides from Marine Algae

(2011) Guangling Jiao et al.   Marine Drugs

Antiviral Activities of Sulfated Polysaccharides Isolated from Sphaerococcus coronopifolius (Rhodophytha, Gigartinales) and Boergeseniella thuyoides (Rhodophyta, Ceramiales)

(2011) Rhimou Bouhlal et al.   Marine Drugs

Portuguese carrageenophytes: Carrageenan composition and geographic distribution of eight species (Gigartinales, Rhodophyta)

(2010) Leonel Pereira et al.   CARBOHYDRATE POLYMERS

Antiviral Drug Resistance: Mechanisms and Clinical Implications

(2010) Lynne Strasfeld et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Radiolysis studies of aqueous κ-carrageenan

(2010) L.V. Abad et al.   NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS

Iota-Carrageenan Is a Potent Inhibitor of Influenza A Virus Infection

(2010) Andreas Leibbrandt et al.   PLoS One

Virucidal activity of polysaccharide extracts from four algal species against herpes simplex virus

(2009) Emma A. Harden et al.   ANTIVIRAL RESEARCH

Radiation degradation studies of carrageenans

(2009) L.V. Abad et al.   CARBOHYDRATE POLYMERS

Mechanism of mild acid hydrolysis of galactan polysaccharides with highly ordered disaccharide repeats leading to a complete series of exclusively odd-numbered oligosaccharides

(2009) Bo Yang et al.   FEBS Journal

The Cyclization of the 3,6-Anhydro-Galactose Ring of  -Carrageenan Is Catalyzed by Two D-Galactose-2,6-Sulfurylases in the Red Alga Chondrus crispus

(2009) S. Genicot-Joncour et al.   PLANT PHYSIOLOGY

Focus on antivirally active sulfated polysaccharides: From structure–activity analysis to clinical evaluation

(2008) Tuhin Ghosh et al.   GLYCOBIOLOGY

Efficacy of Carraguard for prevention of HIV infection in women in South Africa: a randomised, double-blind, placebo-controlled trial

(2008) Stephanie Skoler-Karpoff et al.   LANCET

Iota-Carrageenan is a potent inhibitor of rhinovirus infection

(2008) Andreas Grassauer et al.   Virology Journal

The importance of heparan sulfate in herpesvirus infection

(2008) Christopher D. O’Donnell et al.   VIROLOGICA SINICA