Biosafety of mesoporous silica nanoparticles: a combined experimental and literature study

Mesoporous silica with precisely controlled pores reduces food efficiency and suppresses weight gain in mice

(2020) Mia Rinde et al.   Nanomedicine

One-year chronic toxicity evaluation of single dose intravenously administered silica nanoparticles in mice and their Ex vivo human hemocompatibility

(2020) Raziye Mohammadpour et al.   JOURNAL OF CONTROLLED RELEASE

A nanoscale metal organic frameworks-based vaccine synergises with PD-1 blockade to potentiate anti-tumour immunity

(2020) Xia Li et al.   Nature Communications

Macrophage cell tracking PET imaging using mesoporous silica nanoparticles via in vivo bioorthogonal F-18 labeling

(2019) Hyeon Jin Jeong et al.   BIOMATERIALS

Subchronic toxicity of silica nanoparticles as a function of size and porosity

(2019) Raziye Mohammadpour et al.   JOURNAL OF CONTROLLED RELEASE

Mesoporous silica nanoparticles for tissue‐engineering applications

(2019) Liang Chen et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Red Blood Cell Membrane Bioengineered Zr-89 Labelled Hollow Mesoporous Silica Nanosphere for Overcoming Phagocytosis

(2019) Jun Young Lee et al.   Scientific Reports

Synergistical chemotherapy and cancer immunotherapy using dual drug-delivering and immunopotentiating mesoporous silica

(2019) Xia Li et al.   Applied Materials Today

In vitro and in vivo evaluation of degradation, toxicity, biodistribution, and clearance of silica nanoparticles as a function of size, porosity, density, and composition

(2019) Seyyed Pouya Hadipour Moghaddam et al.   JOURNAL OF CONTROLLED RELEASE

PEGylated lipid bilayer coated mesoporous silica nanoparticles co-delivery of paclitaxel and curcumin leads to increased tumor site drug accumulation and reduced tumor burden

(2019) Jiafeng Gao et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Synergistic effects of stellated fibrous mesoporous silica and synthetic dsRNA analogues for cancer immunotherapy

(2018) Xiupeng Wang et al.   CHEMICAL COMMUNICATIONS

Tailoring inorganic nanoadjuvants towards next-generation vaccines

(2018) Xia Li et al.   CHEMICAL SOCIETY REVIEWS

One-pot green synthesis of doxorubicin loaded-silica nanoparticles for in vivo cancer therapy

(2018) Shan Jiang et al.   Materials Science & Engineering C-Materials for Biological Applications

A Transferrin-Conjugated Hollow Nanoplatform for Redox-Controlled and Targeted Chemotherapy of Tumor with Reduced Inflammatory Reactions

(2018) Jun Zhou et al.   Theranostics

Mesoporous Silica as a Versatile Platform for Cancer Immunotherapy

(2018) Thanh Loc Nguyen et al.   ADVANCED MATERIALS

Cardiac and pulmonary toxicity of mesoporous silica nanoparticles is associated with excessive ROS production and redox imbalance in Wistar rats

(2018) Walaa G. Hozayen et al.   BIOMEDICINE & PHARMACOTHERAPY

Cargo-influences on the biodistribution of hollow mesoporous silica nanoparticles as studied by quantitative 19 F-magnetic resonance imaging

(2017) Alexander Pochert et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Mesoporous Silica Nanoparticles for Drug Delivery: Current Insights

(2017) María Vallet-Regí et al.   MOLECULES

Extra-Large Pore Mesoporous Silica Nanoparticles for Directing in Vivo M2 Macrophage Polarization by Delivering IL-4

(2017) Dohyeong Kwon et al.   NANO LETTERS

Quantitative and correlative biodistribution analysis of 89Zr-labeled mesoporous silica nanoparticles intravenously injected into tumor-bearing mice

(2017) Larissa Kramer et al.   Nanoscale

Autophagy upregulation promotes macrophages to escape mesoporous silica nanoparticle (MSN)-induced NF-κB-dependent inflammation

(2016) Chen Xi et al.   INFLAMMATION RESEARCH

Acute Toxicity Evaluation of Glycosylated Gd3+-Based Silica Nanoprobe

(2016) Bita Mehravi et al.   MOLECULAR IMAGING AND BIOLOGY

Improving paclitaxel pharmacokinetics by using tumor-specific mesoporous silica nanoparticles with intraperitoneal delivery

(2016) Qiang Fu et al.   Nanomedicine-Nanotechnology Biology and Medicine

Comparative in vivo toxicity assessment places multiwalled carbon nanotubes at a higher level than mesoporous silica nanoparticles

(2016) Nidhi Rawat et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Comprehensive Mechanism Analysis of Mesoporous-Silica-Nanoparticle-Induced Cancer Immunotherapy

(2016) Xiupeng Wang et al.   Advanced Healthcare Materials

In Vivo Integrity and Biological Fate of Chelator-Free Zirconium-89-Labeled Mesoporous Silica Nanoparticles

(2015) Feng Chen et al.   ACS Nano

Stimulation of In Vivo Antitumor Immunity with Hollow Mesoporous Silica Nanospheres

(2015) Xiupeng Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bi 2 S 3 -embedded mesoporous silica nanoparticles for efficient drug delivery and interstitial radiotherapy sensitization

(2015) Ming Ma et al.   BIOMATERIALS

A Biodegradation Study of SBA-15 Microparticles in Simulated Body Fluid and in Vivo

(2015) Youngjin Choi et al.   LANGMUIR

Poly(I:C) as cancer vaccine adjuvant: Knocking on the door of medical breakthroughs

(2015) Rachid Ammi et al.   PHARMACOLOGY & THERAPEUTICS

The elements of life and medicines

(2015) P. Chellan et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1

(2015) E. Vacchelli et al.   SCIENCE

Hollow Mesoporous Silica Nanocarriers with Multifunctional Capping Agents for In Vivo Cancer Imaging and Therapy

(2015) Shun Yang et al.   Small

Defined TLR3-specific adjuvant that induces NK and CTL activation without significant cytokine production in vivo

(2015) Misako Matsumoto et al.   Nature Communications

Metal chelate grafting at the surface of mesoporous silica nanoparticles (MSNs): physico-chemical and biomedical imaging assessment

(2015) Myriam Laprise-Pelletier et al.   Journal of Materials Chemistry B

Racotumomab–alum vaccine for the treatment of non-small-cell lung cancer

(2014) Ana María Hernández et al.   Expert Review of Vaccines

Renal interstitial fibrosis induced by high-dose mesoporous silica nanoparticles via the NF-κB signaling pathway

(2014) Chen Xi et al.   International Journal of Nanomedicine

Mesoporous silica particles potentiate antigen-specific T-cell responses

(2014) Natalia Kupferschmidt et al.   Nanomedicine

Particle-size-dependent toxicity and immunogenic activity of mesoporous silica-based adjuvants for tumor immunotherapy

(2013) Xiupeng Wang et al.   Acta Biomaterialia

The absorption, distribution, excretion and toxicity of mesoporous silica nanoparticles in mice following different exposure routes

(2013) Changhui Fu et al.   BIOMATERIALS

The comparative immunotoxicity of mesoporous silica nanoparticles and colloidal silica nanoparticles in mice

(2013) Sang-Hyun Kim et al.   International Journal of Nanomedicine

Increasing Cellular Uptake of Mesoporous Silica Nanoparticles in Human Embryonic Kidney Cell Line 293T Cells by Using Lipofectamine 2000

(2013) Jiandong Wang et al.   Journal of Biomedical Nanotechnology

Smaller Silica Nanorattles Reabsorbed by Intestinal Aggravate Multiple Organs Damage

(2013) Tianlong Liu et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Mesoporous Silica Nanoparticles Act as a Self-Adjuvant for Ovalbumin Model Antigen in Mice

(2013) Donna Mahony et al.   Small

Mesoporous Silica-Calcium Phosphate-Tuberculin Purified Protein Derivative Composites as an Effective Adjuvant for Cancer Immunotherapy

(2013) Xia Li et al.   Advanced Healthcare Materials

Influence of Geometry, Porosity, and Surface Characteristics of Silica Nanoparticles on Acute Toxicity: Their Vasculature Effect and Tolerance Threshold

(2012) Tian Yu et al.   ACS Nano

Multifunctional ZnPc-loaded mesoporous silica nanoparticles for enhancement of photodynamic therapy efficacy by endolysosomal escape

(2012) Jing Tu et al.   BIOMATERIALS

In vivo biodistribution and pharmacokinetics of silica nanoparticles as a function of geometry, porosity and surface characteristics

(2012) Tian Yu et al.   JOURNAL OF CONTROLLED RELEASE

Neutron-Activatable Holmium-Containing Mesoporous Silica Nanoparticles as a Potential Radionuclide Therapeutic Agent for Ovarian Cancer

(2012) A. J. Di Pasqua et al.   JOURNAL OF NUCLEAR MEDICINE

The Shape Effect of Mesoporous Silica Nanoparticles on Biodistribution, Clearance, and Biocompatibility in Vivo

(2011) Xinglu Huang et al.   ACS Nano

Pathological mechanisms of liver injury caused by continuous intraperitoneal injection of silica nanoparticles

(2011) Tianlong Liu et al.   BIOMATERIALS

DNA released from dying host cells mediates aluminum adjuvant activity

(2011) Thomas Marichal et al.   NATURE MEDICINE

Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

(2011) M. Michaud et al.   SCIENCE

Single and repeated dose toxicity of mesoporous hollow silica nanoparticles in intravenously exposed mice

(2010) Tianlong Liu et al.   BIOMATERIALS

The nanosilica hazard: another variable entity

(2010) Dorota Napierska et al.   Particle and Fibre Toxicology

In vivo Biodistribution and Urinary Excretion of Mesoporous Silica Nanoparticles: Effects of Particle Size and PEGylation

(2010) Qianjun He et al.   Small

Biocompatibility, Biodistribution, and Drug-Delivery Efficiency of Mesoporous Silica Nanoparticles for Cancer Therapy in Animals

(2010) Jie Lu et al.   Small

Intracellular Localization and Cytotoxicity of Spherical Mesoporous Silica Nano- and Microparticles

(2009) Qianjun He et al.   Small

Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers☆

(2008) I SLOWING et al.   ADVANCED DRUG DELIVERY REVIEWS

The biocompatibility of mesoporous silicates

(2008) Sarah P. Hudson et al.   BIOMATERIALS