Autophagy upregulation promotes macrophages to escape mesoporous silica nanoparticle (MSN)-induced NF-κB-dependent inflammation

Graphene quantum dots induce apoptosis, autophagy, and inflammatory response via p38 mitogen-activated protein kinase and nuclear factor-κB mediated signaling pathways in activated THP-1 macrophages

(2015) Yiru Qin et al.   TOXICOLOGY

The Practicality of Mesoporous Silica Nanoparticles as Drug Delivery Devices and Progress Toward This Goal

(2014) Robert Roggers et al.   AAPS PHARMSCITECH

Interference in Autophagosome Fusion by Rare Earth Nanoparticles Disrupts Autophagic Flux and Regulation of an Interleukin-1β Producing Inflammasome

(2014) Ruibin Li et al.   ACS Nano

MSN-Mediated Sequential Vascular-to-Cell Nuclear-Targeted Drug Delivery for Efficient Tumor Regression

(2014) Limin Pan et al.   ADVANCED MATERIALS

Inhibition of autophagy enhances the anticancer activity of silver nanoparticles

(2014) Jun Lin et al.   Autophagy

In vivo toxicity of orally administrated silicon dioxide nanoparticles in healthy adult mice

(2014) Ramin Hassankhani et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Importance of Kupffer Cells in the Development of Acute Liver Injuries in Mice

(2014) Hiroko Tsutsui et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Silica nanoparticles induce autophagy and endothelial dysfunction via the PI3K/Akt/mTOR signaling pathway

(2014) Duan et al.   International Journal of Nanomedicine

Autophagy: Detection, regulation and its role in cancer and therapy response

(2014) Pia Hönscheid et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Silica nanoparticles enhance autophagic activity, disturb endothelial cell homeostasis and impair angiogenesis

(2014) Junchao Duan et al.   Particle and Fibre Toxicology

Functional Nanovalves on Protein-Coated Nanoparticles for In vitro and In vivo Controlled Drug Delivery

(2014) Angela A. Hwang et al.   Small

Magnetic iron oxide nanoparticles induce autophagy preceding apoptosis through mitochondrial damage and ER stress in RAW264.7 cells

(2014) Eun-Jung Park et al.   TOXICOLOGY IN VITRO

Zinc oxide nanoparticles induce apoptosis by enhancement of autophagy via PI3K/Akt/mTOR inhibition

(2014) Ruchi Roy et al.   TOXICOLOGY LETTERS

Triptolide-induced oxidative stress involved with Nrf2 contribute to cardiomyocyte apoptosis through mitochondrial dependent pathways

(2014) Jie Zhou et al.   TOXICOLOGY LETTERS

Chloroquine inhibits HMGB1 inflammatory signaling and protects mice from lethal sepsis

(2013) Minghua Yang et al.   BIOCHEMICAL PHARMACOLOGY

The absorption, distribution, excretion and toxicity of mesoporous silica nanoparticles in mice following different exposure routes

(2013) Changhui Fu et al.   BIOMATERIALS

EGFR-Mediated Beclin 1 Phosphorylation in Autophagy Suppression, Tumor Progression, and Tumor Chemoresistance

(2013) Yongjie Wei et al.   CELL

Autophagy: A critical regulator of cellular metabolism and homeostasis

(2013) Stefan W. Ryter et al.   MOLECULES AND CELLS

Silica nanoparticle uptake induces survival mechanism in A549 cells by the activation of autophagy but not apoptosis

(2013) Jakub Stanislaw Nowak et al.   TOXICOLOGY LETTERS

Cross talk between NADPH oxidase and autophagy in pulmonary artery endothelial cells with intrauterine persistent pulmonary hypertension

(2012) Ru-Jeng Teng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Interplay between apoptotic and autophagy pathways after exposure to cerium dioxide nanoparticles in human monocytes

(2012) Salik Hussain et al.   Autophagy

Amorphous nanosilicas induce consumptive coagulopathy after systemic exposure

(2012) Hiromi Nabeshi et al.   NANOTECHNOLOGY

Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity

(2012) Stephan T Stern et al.   Particle and Fibre Toxicology

Dietary Blue Pigments Derived from Genipin, Attenuate Inflammation by Inhibiting LPS-Induced iNOS and COX-2 Expression via the NF-κB Inactivation

(2012) Qiang-Song Wang et al.   PLoS One

Systemic distribution, nuclear entry and cytotoxicity of amorphous nanosilica following topical application

(2011) Hiromi Nabeshi et al.   BIOMATERIALS

The comparative effects of mesoporous silica nanoparticles and colloidal silica on inflammation and apoptosis

(2011) Soyoung Lee et al.   BIOMATERIALS

Pathological mechanisms of liver injury caused by continuous intraperitoneal injection of silica nanoparticles

(2011) Tianlong Liu et al.   BIOMATERIALS

Methyl-1-hydroxy-2-naphthoate, a novel naphthol derivative, inhibits lipopolysaccharide-induced inflammatory response in macrophages via suppression of NF-κB, JNK and p38 MAPK pathways

(2011) Jun-Yan Zhang et al.   INFLAMMATION RESEARCH

Silica nanoconstruct cellular toleration threshold in vitro

(2011) Heather L. Herd et al.   JOURNAL OF CONTROLLED RELEASE

Autophagy-related proteins Beclin-1 and LC3 predict cetuximab efficacy in advanced colorectal cancer

(2011) Gui-Fang Guo   WORLD JOURNAL OF GASTROENTEROLOGY

Multifunctional Gold Nanoshells on Silica Nanorattles: A Platform for the Combination of Photothermal Therapy and Chemotherapy with Low Systemic Toxicity

(2010) Huiyu Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Autophagosome Formation and Molecular Mechanism of Autophagy

(2010) Isei Tanida   ANTIOXIDANTS & REDOX SIGNALING

Single and repeated dose toxicity of mesoporous hollow silica nanoparticles in intravenously exposed mice

(2010) Tianlong Liu et al.   BIOMATERIALS

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase

(2010) You-Tong Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mesoporosity and Functional Group Dependent Endocytosis and Cytotoxicity of Silica Nanomaterials

(2009) Zhimin Tao et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Histological analysis of 70-nm silica particles-induced chronic toxicity in mice

(2009) Hikaru Nishimori et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Rapamycin protects against rotenone-induced apoptosis through autophagy induction

(2009) T. Pan et al.   NEUROSCIENCE

Mesoporous silica nanoparticles enhance MTT formazan exocytosis in HeLa cells and astrocytes

(2009) Matthieu Fisichella et al.   TOXICOLOGY IN VITRO

Bioconjugated quantum dots for in vivo molecular and cellular imaging☆

(2008) A SMITH et al.   ADVANCED DRUG DELIVERY REVIEWS

Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers☆

(2008) I SLOWING et al.   ADVANCED DRUG DELIVERY REVIEWS

Endocytosis of a single mesoporous silica nanoparticle into a human lung cancer cell observed by differential interference contrast microscopy

(2008) Wei Sun et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Mesoporous Silica Nanoparticles Inhibit Cellular Respiration

(2008) Zhimin Tao et al.   NANO LETTERS

Autophagy as an ultrastructural marker of heavy metal toxicity in human cord blood hematopoietic stem cells

(2008) Mario Di Gioacchino et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Mesoporous Silica Nanoparticles for Reducing Hemolytic Activity Towards Mammalian Red Blood Cells

(2008) Igor I. Slowing et al.   Small