Sarcopenia and frailty in decompensated cirrhosis

Mitochondrial TCA cycle metabolites control physiology and disease

(2020) Inmaculada Martínez-Reyes et al.   Nature Communications

Changes in frailty are associated with waitlist mortality in patients with cirrhosis

(2020) Jennifer C. Lai et al.   JOURNAL OF HEPATOLOGY

Use of Skeletal Muscle Index as a Predictor of Wait List Mortality in Patients with End‐Stage Liver Disease

(2020) Matthew R. Kappus et al.   LIVER TRANSPLANTATION

Cystatin C and Sarcopenia Predict Acute on Chronic Liver Failure Development and Mortality in Patients on the Liver Transplant Waiting List

(2020) Ezequiel Mauro et al.   TRANSPLANTATION

Myogenic Response to Increasing Concentrations of Ammonia Differs between Mammalian, Avian, and Fish Species: Cell Differentiation and Genetic Study

(2020) Emily Miramontes et al.   Genes

Validation of the Clinical Frailty Scale for the Prediction of Mortality in Patients With Liver Cirrhosis

(2020) Wolfgang M. Kremer et al.   Clinical and Translational Gastroenterology

ESPEN guideline on clinical nutrition in liver disease

(2019) Mathias Plauth et al.   CLINICAL NUTRITION

Frailty Associated With Waitlist Mortality Independent of Ascites and Hepatic Encephalopathy in a Multi-Center Study

(2019) Jennifer C. Lai et al.   GASTROENTEROLOGY

Are Predictive Energy Expenditure Equations Accurate in Cirrhosis?

(2019) Tannaz Eslamparast et al.   Nutrients

Use of Dual X-ray Absorptiometry in men with advanced cirrhosis to predict sarcopenia-associated mortality risk

(2019) Marie Sinclair et al.   LIVER INTERNATIONAL

The modification of quantity and quality of muscle mass improves the cognitive impairment after TIPS

(2019) Stefania Gioia et al.   LIVER INTERNATIONAL

Ethanol sensitizes skeletal muscle to ammonia-induced molecular perturbations

(2019) Sashi Kant et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impaired Ribosomal Biogenesis by Non-Canonical Degradation of β-catenin during Hyperammonemia

(2019) Gangarao Davuluri et al.   MOLECULAR AND CELLULAR BIOLOGY

Clinical review: peripheral muscular ultrasound in the ICU

(2019) Paolo Formenti et al.   Annals of Intensive Care

Sarcopenia Is Associated With Development of Acute-on-Chronic Liver Failure in Decompensated Liver Cirrhosis Receiving Transjugular Intrahepatic Portosystemic Shunt

(2019) Michael Praktiknjo et al.   Clinical and Translational Gastroenterology

Frailty Assessment in Animal Models

(2019) Stefan D. Heinze-Milne et al.   GERONTOLOGY

A North American Expert Opinion Statement on Sarcopenia in Liver Transplantation

(2019) Elizabeth J. Carey et al.   HEPATOLOGY

Effects of beta‐hydroxy‐beta‐methylbutyrate supplementation on skeletal muscle in healthy and cirrhotic rats

(2019) Milan Holeček et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Nutritional Assessment in Inpatients with Cirrhosis can be Improved after Training and is Associated with Lower Readmissions

(2019) Bradley Reuter et al.   LIVER TRANSPLANTATION

Handgrip strength adds more prognostic value to the MELD score than imaging‐based measures of muscle mass in men with cirrhosis

(2019) Marie Sinclair et al.   LIVER TRANSPLANTATION

The value of different CT‐based methods for diagnosing low muscle mass and predicting mortality in patients with cirrhosis

(2019) Rafael Paternostro et al.   LIVER INTERNATIONAL

Oxidative stress mediates ethanol-induced skeletal muscle mitochondrial dysfunction and dysregulated protein synthesis and autophagy

(2019) Avinash Kumar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Continued muscle loss increases mortality in cirrhosis: Impact of aetiology of liver disease

(2019) Nicole Welch et al.   LIVER INTERNATIONAL

CT-assessed sarcopenia is a predictive factor for both long-term and short-term outcomes in gastrointestinal oncology patients: a systematic review and meta-analysis

(2019) Huaiying Su et al.   CANCER IMAGING

Hyperammonemia and proteostasis in cirrhosis

(2018) Srinivasan Dasarathy et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Fat-free muscle mass in magnetic resonance imaging predicts acute-on-chronic liver failure and survival in decompensated cirrhosis

(2018) Michael Praktiknjo et al.   HEPATOLOGY

Myosteatosis and sarcopenia are associated with hepatic encephalopathy in patients with cirrhosis

(2018) Rahima A. Bhanji et al.   Hepatology International

Karnofsky Performance Status Before and After Liver Transplantation Predicts Graft and Patient Survival

(2018) Paul J. Thuluvath et al.   JOURNAL OF HEPATOLOGY

Exercise in Cirrhosis: Translating evidence and experience to practice

(2018) Puneeta Tandon et al.   JOURNAL OF HEPATOLOGY

A low muscle mass increases mortality in compensated cirrhotic patients with sepsis

(2018) Cristina Lucidi et al.   LIVER INTERNATIONAL

Sarcopenic obesity in cirrhosis-The confluence of 2 prognostic titans

(2018) Tannaz Eslamparast et al.   LIVER INTERNATIONAL

EASL Clinical Practice Guidelines on nutrition in chronic liver disease

(2018) Manuela Merli et al.   JOURNAL OF HEPATOLOGY

Differing Impact of Sarcopenia and Frailty in Non-Alcoholic Steatohepatitis (NASH) and Alcoholic Liver Disease (ALD)

(2018) Rahima A Bhanji et al.   LIVER TRANSPLANTATION

Poor performance of psoas muscle index for identification of patients with higher waitlist mortality risk in cirrhosis

(2018) Maryam Ebadi et al.   Journal of Cachexia Sarcopenia and Muscle

Loss of paraspinal muscle mass is a gender-specific consequence of cirrhosis that predicts complications and death

(2018) Cornelius Engelmann et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Assessment of muscle mass depletion in chronic liver disease; dual-energy X-ray absorptiometry compared with computed tomography

(2018) Catarina Lindqvist et al.   NUTRITION

Ammonia lowering reverses sarcopenia of cirrhosis by restoring skeletal muscle proteostasis

(2017) Avinash Kumar et al.   HEPATOLOGY

The Role of Growth Hormone and Insulin-Like Growth Factor-I in the Liver

(2017) Yutaka Takahashi   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Development of a Rat Clinical Frailty Index

(2017) Amy Yorke et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Exercise and physical activity for patients with end-stage liver disease: Improving functional status and sarcopenia while on the transplant waiting list

(2017) Andrés Duarte-Rojo et al.   LIVER TRANSPLANTATION

Myostatin and beyond in cirrhosis: all roads lead to sarcopenia

(2017) Srinivasan Dasarathy   Journal of Cachexia Sarcopenia and Muscle

A Rapid Bedside Screen to Predict Unplanned Hospitalization and Death in Outpatients With Cirrhosis: A Prospective Evaluation of the Clinical Frailty Scale

(2016) Puneeta Tandon et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Frailty as Tested by Gait Speed is an Independent Risk Factor for Cirrhosis Complications that Require Hospitalization

(2016) Michael A Dunn et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Depression and Frailty in Patients With End-Stage Liver Disease Referred for Transplant Evaluation

(2016) D. C. Cron et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Comparing the Variability Between Measurements for Sarcopenia Using Magnetic Resonance Imaging and Computed Tomography Imaging

(2016) P. Tandon et al.   AMERICAN JOURNAL OF TRANSPLANTATION

A Model to Identify Sarcopenia in Patients With Cirrhosis

(2016) Puneeta Tandon et al.   Clinical Gastroenterology and Hepatology

Efficacy of Nutritional Therapy for Patients With Cirrhosis and Minimal Hepatic Encephalopathy in a Randomized Trial

(2016) Sudhir Maharshi et al.   Clinical Gastroenterology and Hepatology

Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient

(2016) Beth E. Taylor et al.   CRITICAL CARE MEDICINE

A Karnofsky performance status-based score predicts death after hospital discharge in patients with cirrhosis

(2016) Puneeta Tandon et al.   HEPATOLOGY

Metabolic adaptation of skeletal muscle to hyperammonemia drives the beneficial effects of l-leucine in cirrhosis

(2016) Gangarao Davuluri et al.   JOURNAL OF HEPATOLOGY

Testosterone therapy increases muscle mass in men with cirrhosis and low testosterone: A randomised controlled trial

(2016) Marie Sinclair et al.   JOURNAL OF HEPATOLOGY

Sarcopenia from mechanism to diagnosis and treatment in liver disease

(2016) Srinivasan Dasarathy et al.   JOURNAL OF HEPATOLOGY

Hyperammonaemia-induced skeletal muscle mitochondrial dysfunction results in cataplerosis and oxidative stress

(2016) Gangarao Davuluri et al.   JOURNAL OF PHYSIOLOGY-LONDON

A Comparison of Muscle Function, Mass, and Quality in Liver Transplant Candidates

(2016) Connie W. Wang et al.   TRANSPLANTATION

Signatures of early frailty in the gut microbiota

(2016) Matthew A. Jackson et al.   Genome Medicine

Malnutrition and sarcopenia predict post-liver transplantation outcomes independently of the Model for End-stage Liver Disease score

(2016) Maria Kalafateli et al.   Journal of Cachexia Sarcopenia and Muscle

Animal models of frailty: current applications in clinical research

(2016) Alice Kane et al.   Clinical Interventions in Aging

Muscle at Risk: The Multiple Impacts of Ammonia on Sarcopenia and Frailty in Cirrhosis

(2016) Hui-Wei Chen et al.   Clinical and Translational Gastroenterology

Relationship between sarcopenia, six-minute walk distance and health-related quality of life in liver transplant candidates

(2015) Anitha Yadav et al.   CLINICAL TRANSPLANTATION

Standard assessments of frailty are validated predictors of mortality in hospitalized patients with cirrhosis

(2015) Elliot B. Tapper et al.   HEPATOLOGY

Metabolic and molecular responses to leucine-enriched branched chain amino acid supplementation in the skeletal muscle of alcoholic cirrhosis

(2015) Cynthia Tsien et al.   HEPATOLOGY

Testosterone in men with advanced liver disease: Abnormalities and implications

(2015) Marie Sinclair et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Muscle wasting in disease: molecular mechanisms and promising therapies

(2015) Shenhav Cohen et al.   NATURE REVIEWS DRUG DISCOVERY

Sarcopenia in the prognosis of cirrhosis: Going beyond the MELD score

(2015) Hee Yeon Kim   WORLD JOURNAL OF GASTROENTEROLOGY

Inclusion of Sarcopenia Within MELD (MELD-Sarcopenia) and the Prediction of Mortality in Patients With Cirrhosis

(2015) Aldo J Montano-Loza et al.   Clinical and Translational Gastroenterology

Frailty Predicts Waitlist Mortality in Liver Transplant Candidates

(2014) J. C. Lai et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Alcohol-induced autophagy contributes to loss in skeletal muscle mass

(2014) Samjhana Thapaliya et al.   Autophagy

Bedside ultrasound measurement of skeletal muscle

(2014) Marina Mourtzakis et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Ribosome Biogenesis: Emerging Evidence for a Central Role in the Regulation of Skeletal Muscle Mass

(2014) Thomas Chaillou et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Prognostic value of muscle atrophy in cirrhosis using psoas muscle thickness on computed tomography

(2014) François Durand et al.   JOURNAL OF HEPATOLOGY

Sarcopenia as a Useful Predictor for Long-Term Mortality in Cirrhotic Patients with Ascites

(2014) Tae Yeob Kim et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Renin-angiotensin system and fibrosis in non-alcoholic fatty liver disease

(2014) George B Goh et al.   LIVER INTERNATIONAL

Impact of quality as well as quantity of skeletal muscle on outcomes after liver transplantation

(2014) Yuhei Hamaguchi et al.   LIVER TRANSPLANTATION

Meta-analysis: oral or enteral nutritional supplementation in cirrhosis

(2013) M. Ney et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Interleukin-6 myokine signaling in skeletal muscle: a double-edged sword?

(2013) Pura Muñoz-Cánoves et al.   FEBS Journal

The nutritional management of hepatic encephalopathy in patients with cirrhosis: International society for hepatic encephalopathy and nitrogen metabolism consensus

(2013) Piero Amodio et al.   HEPATOLOGY

Sarcopenia and a physiologically low respiratory quotient in patients with cirrhosis: a prospective controlled study

(2013) Cathy Glass et al.   JOURNAL OF APPLIED PHYSIOLOGY

Clinically Relevant Frailty Index for Mice

(2013) H. Liu et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Muscle mass predicts outcomes following liver transplantation

(2013) Andrea DiMartini et al.   LIVER TRANSPLANTATION

Hyperammonemia in cirrhosis induces transcriptional regulation of myostatin by an NF- B-mediated mechanism

(2013) J. Qiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hyperammonemia-mediated autophagy in skeletal muscle contributes to sarcopenia of cirrhosis

(2012) Jia Qiu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Malnutrition in Cirrhosis: Contribution and Consequences of Sarcopenia on Metabolic and Clinical Responses

(2012) Pranav Periyalwar et al.   Clinics in Liver Disease

Consilience in sarcopenia of cirrhosis

(2012) Srinivasan Dasarathy   Journal of Cachexia Sarcopenia and Muscle

Oral acetyl-l-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a randomized, double-blind, placebo-controlled study

(2011) Michele Malaguarnera et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Late evening snack: Exploiting a period of anabolic opportunity in cirrhosis

(2011) Cynthia D Tsien et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Sarcopenia associated with portosystemic shunting is reversed by follistatin

(2010) Srinivasan Dasarathy et al.   JOURNAL OF HEPATOLOGY

Six-minute walk distance predicts mortality in liver transplant candidates

(2010) Elizabeth J. Carey et al.   LIVER TRANSPLANTATION

Neural mechanisms of ageing and cognitive decline

(2010) Nicholas A. Bishop et al.   NATURE

Inflammation and frailty measures in older people

(2009) Ruth E. Hubbard et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Nocturnal nutritional supplementation improves total body protein status of patients with liver cirrhosis: A randomized 12-month trial

(2008) Lindsay D. Plank et al.   HEPATOLOGY

Nuclear factor-kappa B signaling in skeletal muscle atrophy

(2008) Hong Li et al.   JOURNAL OF MOLECULAR MEDICINE-JMM