Ammonia lowering reverses sarcopenia of cirrhosis by restoring skeletal muscle proteostasis

Metabolic adaptation of skeletal muscle to hyperammonemia drives the beneficial effects of l-leucine in cirrhosis

(2016) Gangarao Davuluri et al.   JOURNAL OF HEPATOLOGY

Hyperammonaemia-induced skeletal muscle mitochondrial dysfunction results in cataplerosis and oxidative stress

(2016) Gangarao Davuluri et al.   JOURNAL OF PHYSIOLOGY-LONDON

Metabolic and molecular responses to leucine-enriched branched chain amino acid supplementation in the skeletal muscle of alcoholic cirrhosis

(2015) Cynthia Tsien et al.   HEPATOLOGY

Clinical and prognostic role of ammonia in advanced decompensated heart failure. The cardio-abdominal syndrome?

(2015) Simone Frea et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Alcohol-induced autophagy contributes to loss in skeletal muscle mass

(2014) Samjhana Thapaliya et al.   Autophagy

Post-liver transplantation sarcopenia in cirrhosis: A prospective evaluation

(2014) Cynthia Tsien et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Branched-chain amino acids and ammonia metabolism in liver disease: Therapeutic implications

(2013) Milan Holecek   NUTRITION

Hyperammonemia in cirrhosis induces transcriptional regulation of myostatin by an NF- B-mediated mechanism

(2013) J. Qiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hyperammonemia-mediated autophagy in skeletal muscle contributes to sarcopenia of cirrhosis

(2012) Jia Qiu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Ammonia-Lowering Strategies for the Treatment of Hepatic Encephalopathy

(2012) C F Rose   CLINICAL PHARMACOLOGY & THERAPEUTICS

Malnutrition in Cirrhosis: Contribution and Consequences of Sarcopenia on Metabolic and Clinical Responses

(2012) Pranav Periyalwar et al.   Clinics in Liver Disease

Severe muscle depletion in patients on the liver transplant wait list: Its prevalence and independent prognostic value

(2012) Puneeta Tandon et al.   LIVER TRANSPLANTATION

Muscle depletion increases the risk of overt and minimal hepatic encephalopathy: results of a prospective study

(2012) Manuela Merli et al.   METABOLIC BRAIN DISEASE

Rifaximin, but not growth factor 1, reduces brain edema in cirrhotic rats

(2012) Gemma Òdena   WORLD JOURNAL OF GASTROENTEROLOGY

The dysfunction of ammonia in heart failure increases with an increase in the intensity of resistance exercise, even with the use of appropriate drug therapy

(2012) Wladimir M Medeiros et al.   European Journal of Preventive Cardiology

Consilience in sarcopenia of cirrhosis

(2012) Srinivasan Dasarathy   Journal of Cachexia Sarcopenia and Muscle

Ammonia reduction with ornithine phenylacetate restores brain eNOS activity via the DDAH-ADMA pathway in bile duct-ligated cirrhotic rats

(2011) Vairappan Balasubramaniyan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Muscle Wasting Is Associated With Mortality in Patients With Cirrhosis

(2011) Aldo J. Montano–Loza et al.   Clinical Gastroenterology and Hepatology

Sarcopenia associated with portosystemic shunting is reversed by follistatin

(2010) Srinivasan Dasarathy et al.   JOURNAL OF HEPATOLOGY

Sarcopenia and Mortality after Liver Transplantation

(2010) Michael J. Englesbe et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Ammonia: A Diffusible Factor Released by Proliferating Cells That Induces Autophagy

(2010) G. Marino et al.   Science Signaling

Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size

(2009) Anne Ulrike Trendelenburg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Efficacy of L-Ornithine L-Aspartate in Acute Liver Failure: A Double-Blind, Randomized, Placebo-Controlled Study

(2009) Subrat Kumar Acharya et al.   GASTROENTEROLOGY

Backflux of ammonia from brain to blood in human subjects with and without hepatic encephalopathy

(2008) Michael Sørensen et al.   METABOLIC BRAIN DISEASE