Regulation of Oxygen Homeostasis at the Intestinal Epithelial Barrier Site

Lost in application: Measuring hypoxia for radiotherapy optimisation

(2021) Niluja Thiruthaneeswaran et al.   EUROPEAN JOURNAL OF CANCER

Genetic approaches to understand cellular responses to oxygen availability

(2021) Brian M. Ortmann et al.   FEBS Journal

Cellular adaptation to hypoxia through hypoxia inducible factors and beyond

(2020) Pearl Lee et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondrial TCA cycle metabolites control physiology and disease

(2020) Inmaculada Martínez-Reyes et al.   Nature Communications

Oxygen battle in the gut: Hypoxia and hypoxia-inducible factors in metabolic and inflammatory responses in the intestine

(2020) Rashi Singhal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biological validation of electron paramagnetic resonance (EPR) image oxygen thresholds in tissue

(2020) Inna Gertsenshteyn et al.   JOURNAL OF PHYSIOLOGY-LONDON

Presenting symptoms in inflammatory bowel disease: descriptive analysis of a community-based inception cohort

(2019) Bryce Perler et al.   BMC GASTROENTEROLOGY

The Thermic Effect of Food: A Review

(2019) Manuel Calcagno et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism

(2019) José Luís Fachi et al.   Cell Reports

Repeatability and reproducibility of longitudinal relaxation rate in 12 small-animal MRI systems

(2019) John C. Waterton et al.   MAGNETIC RESONANCE IMAGING

Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis

(2019) Nupur K. Das et al.   Cell Metabolism

Mitocellular communication: Shaping health and disease

(2019) Adrienne Mottis et al.   SCIENCE

Metabolic adaptation of cancer and immune cells mediated by hypoxia-inducible factors

(2018) Debangshu Samanta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Mitochondrial function — gatekeeper of intestinal epithelial cell homeostasis

(2018) Eva Rath et al.   Nature Reviews Gastroenterology & Hepatology

Regulation of chromatin and gene expression by metabolic enzymes and metabolites

(2018) Xinjian Li et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases

(2018) Rachel Fellows et al.   Nature Communications

The Metabolic Sensor GPR43 Receptor Plays a Role in the Control of Klebsiella pneumoniae Infection in the Lung

(2018) Izabela Galvão et al.   Frontiers in Immunology

Enteric Microbiota–Gut–Brain Axis from the Perspective of Nuclear Receptors

(2018) Kalina Duszka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Imaging tumour hypoxia with oxygen-enhanced MRI and BOLD MRI

(2018) James O'Connor et al.   BRITISH JOURNAL OF RADIOLOGY

Colonocyte metabolism shapes the gut microbiota

(2018) Yael Litvak et al.   SCIENCE

Mitochondria control acute and chronic responses to hypoxia

(2017) G.S. McElroy et al.   EXPERIMENTAL CELL RESEARCH

Tissue metabolism and host-microbial interactions in the intestinal mucosa

(2017) Carlene Chun et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxygen as a driver of gut dysbiosis

(2017) Fabian Rivera-Chávez et al.   FREE RADICAL BIOLOGY AND MEDICINE

PPARγ Modulates Long Chain Fatty Acid Processing in the Intestinal Epithelium

(2017) Kalina Duszka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The IBD interactome: an integrated view of aetiology, pathogenesis and therapy

(2017) Heitor S. P. de Souza et al.   Nature Reviews Gastroenterology & Hepatology

Intestinal hypoxia and hypoxia-induced signalling as therapeutic targets for IBD

(2017) Sophie Van Welden et al.   Nature Reviews Gastroenterology & Hepatology

Microbiota-activated PPAR-γ signaling inhibits dysbiotic Enterobacteriaceae expansion

(2017) Mariana X. Byndloss et al.   SCIENCE

Intrinsic Autophagy Is Required for the Maintenance of Intestinal Stem Cells and for Irradiation-Induced Intestinal Regeneration

(2017) Jumpei Asano et al.   Cell Reports

Commensal gut bacteria modulate phosphorylation-dependent PPARγ transcriptional activity in human intestinal epithelial cells

(2017) Malgorzata Nepelska et al.   Scientific Reports

Role of Intestinal HIF-2α in Health and Disease

(2016) Sadeesh K. Ramakrishnan et al.   Annual Review of Physiology

The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites

(2016) Gerard E. Kaiko et al.   CELL

Dietary fiber and the short-chain fatty acid acetate promote resolution of neutrophilic inflammation in a model of gout in mice

(2016) Angélica T. Vieira et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Distinct cytoprotective roles of pyruvate and ATP by glucose metabolism on epithelial necroptosis and crypt proliferation in ischaemic gut

(2016) Ching-Ying Huang et al.   JOURNAL OF PHYSIOLOGY-LONDON

TCA Cycle and Mitochondrial Membrane Potential Are Necessary for Diverse Biological Functions

(2016) Inmaculada Martínez-Reyes et al.   MOLECULAR CELL

The hypoxia-inducible factor (HIF) couples immunity with metabolism

(2016) Doug N. Halligan et al.   SEMINARS IN IMMUNOLOGY

Lipids Reprogram Metabolism to Become a Major Carbon Source for Histone Acetylation

(2016) Eoin McDonnell et al.   Cell Reports

Bidirectional communication between the Aryl hydrocarbon Receptor (AhR) and the microbiome tunes host metabolism

(2016) Agata Korecka et al.   npj Biofilms and Microbiomes

Physiologic hypoxia and oxygen homeostasis in the healthy intestine. A Review in the Theme: Cellular Responses to Hypoxia

(2015) Leon Zheng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Luminescent sensing and imaging of oxygen: Fierce competition to the Clark electrode

(2015) Otto S. Wolfbeis   BIOESSAYS

Mitochondrial ROS Signaling in Organismal Homeostasis

(2015) Gerald S. Shadel et al.   CELL

Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function

(2015) Caleb J. Kelly et al.   Cell Host & Microbe

Gut biogeography of the bacterial microbiota

(2015) Gregory P. Donaldson et al.   NATURE REVIEWS MICROBIOLOGY

Oxygen Sensing and Homeostasis

(2015) Nanduri R. Prabhakar et al.   PHYSIOLOGY

High resolution imaging of intracellular oxygen concentration by phosphorescence lifetime

(2015) Hiromi Kurokawa et al.   Scientific Reports

The Meaning, Measurement and Modification of Hypoxia in the Laboratory and the Clinic

(2014) E.M. Hammond et al.   CLINICAL ONCOLOGY

Correlation Between Intraluminal Oxygen Gradient and Radial Partitioning of Intestinal Microbiota

(2014) Lindsey Albenberg et al.   GASTROENTEROLOGY

Transmigrating Neutrophils Shape the Mucosal Microenvironment through Localized Oxygen Depletion to Influence Resolution of Inflammation

(2014) Eric L. Campbell et al.   IMMUNITY

An integrated catalog of reference genes in the human gut microbiome

(2014) Junhua Li et al.   NATURE BIOTECHNOLOGY

Mitochondrial pathology: stress signals from the energy factory

(2014) Nuno Raimundo   TRENDS IN MOLECULAR MEDICINE

Pan-genomic binding of hypoxia-inducible transcription factors

(2013) Johannes Schödel et al.   BIOLOGICAL CHEMISTRY

Increased Proportions of Bifidobacterium and the Lactobacillus Group and Loss of Butyrate-Producing Bacteria in Inflammatory Bowel Disease

(2013) W. Wang et al.   JOURNAL OF CLINICAL MICROBIOLOGY

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

(2013) Gijs den Besten et al.   JOURNAL OF LIPID RESEARCH

Lactobacillus GG and Tributyrin Supplementation Reduce Antibiotic-Induced Intestinal Injury

(2013) Gail Cresci et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Fundamental role for HIF-1α in constitutive expression of human β defensin-1

(2013) C J Kelly et al.   Mucosal Immunology

Adult intestinal stem cells: critical drivers of epithelial homeostasis and regeneration

(2013) Nick Barker   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43

(2013) Ikuo Kimura et al.   Nature Communications

Microbial butyrate and its role for barrier function in the gastrointestinal tract

(2012) Svenja Plöger et al.   Annals of the New York Academy of Sciences

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

The gut microbiota in IBD

(2012) Chaysavanh Manichanh et al.   Nature Reviews Gastroenterology & Hepatology

Exogenous Stimuli Maintain Intraepithelial Lymphocytes via Aryl Hydrocarbon Receptor Activation

(2011) Ying Li et al.   CELL

The Microbiome and Butyrate Regulate Energy Metabolism and Autophagy in the Mammalian Colon

(2011) Dallas R. Donohoe et al.   Cell Metabolism

Inflammation and cellular stress: a mechanistic link between immune-mediated and metabolically driven pathologies

(2011) Eva Rath et al.   EUROPEAN JOURNAL OF NUTRITION

Hypoxia and Metabolic Factors That Influence Inflammatory Bowel Disease Pathogenesis

(2011) Louise E. Glover et al.   GASTROENTEROLOGY

Hypoxia: an alarm signal during intestinal inflammation

(2010) Sean P. Colgan et al.   Nature Reviews Gastroenterology & Hepatology

Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon

(2010) L. Peyrin-Biroulet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia-induced changes in pulmonary and systemic vascular resistance: Where is the O2 sensor?

(2010) Gregory B. Waypa et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

The Role of NF-κB in Hypoxia-Induced Gene Expression

(2009) Cormac T. Taylor et al.   Annals of the New York Academy of Sciences

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL

Polysaccharide utilization by gut bacteria: potential for new insights from genomic analysis

(2008) Harry J. Flint et al.   NATURE REVIEWS MICROBIOLOGY