Dysfunction of the Neurovascular Unit in Ischemic Stroke: Highlights on microRNAs and Exosomes as Potential Biomarkers and Therapy
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Dysfunction of the Neurovascular Unit in Ischemic Stroke: Highlights on microRNAs and Exosomes as Potential Biomarkers and Therapy
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 11, Pages 5621
Publisher
MDPI AG
Online
2021-05-26
DOI
10.3390/ijms22115621
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Neurovascular Unit: A critical role in ischemic stroke
- (2021) Liyun Wang et al. CNS Neuroscience & Therapeutics
- Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke
- (2021) Jin Yang et al. Cell Death & Disease
- Exosomal microRNA-22-3p alleviates cerebral ischemic injury by modulating KDM6B/BMP2/BMF axis
- (2021) Yamei Zhang et al. Stem Cell Research & Therapy
- The effects of trifluoperazine on brain edema, aquaporin-4 expression and metabolic markers during the acute phase of stroke using photothrombotic mouse model
- (2021) Nicole J. Sylvain et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Advances in Applying Computer-Aided Drug Design for Neurodegenerative Diseases
- (2021) Mootaz M. Salman et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Astrocyte Activation in Neurovascular Damage and Repair Following Ischaemic Stroke
- (2021) Adjanie Patabendige et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Bone marrow mesenchymal stem cell-derived exosomes attenuate cerebral ischemia-reperfusion injury-induced neuroinflammation and pyroptosis by modulating microglia M1/M2 phenotypes
- (2021) Xiaoli Liu et al. EXPERIMENTAL NEUROLOGY
- The Effect of Exosomes Derived from Bone Marrow Stem Cells in Combination with Rosuvastatin on Functional Recovery and Neuroprotection in Rats After Ischemic Stroke
- (2020) Mohsen Safakheil et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- MSCs-Derived Exosomes Attenuate Acute Brain Injury and Inhibit Microglial Inflammation by Reversing CysLT2R-ERK1/2 Mediated Microglia M1 Polarization
- (2020) Yangmin Zhao et al. NEUROCHEMICAL RESEARCH
- Glial Cells: Role of the Immune Response in Ischemic Stroke
- (2020) Shenbin Xu et al. Frontiers in Immunology
- Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema
- (2020) Philip Kitchen et al. CELL
- Astrocyte-derived exosomes transfer miR-190b to inhibit oxygen and glucose deprivation-induced autophagy and neuronal apoptosis
- (2020) Xiaoxi Pei et al. CELL CYCLE
- Mesenchymal Stem Cell-Derived Extracellular Vesicles: Challenges in Clinical Applications
- (2020) Austin Gowen et al. Frontiers in Cell and Developmental Biology
- Brain Endothelial Cell-Derived Exosomes Induce Neuroplasticity in Rats with Ischemia/Reperfusion Injury
- (2020) Beiyao Gao et al. ACS Chemical Neuroscience
- Moderate exercise has beneficial effects on mouse ischemic stroke by enhancing the functions of circulating endothelial progenitor cell-derived exosomes
- (2020) Jinju Wang et al. EXPERIMENTAL NEUROLOGY
- Vascular Endothelial Cell-derived Exosomes Protect Neural Stem Cells Against Ischemia/reperfusion Injury
- (2020) Shaoting Zhou et al. NEUROSCIENCE
- Multicellular 3D Neurovascular Unit Model for Assessing Hypoxia and Neuroinflammation Induced Blood-Brain Barrier Dysfunction
- (2020) Goodwell Nzou et al. Scientific Reports
- miR-132-3p priming enhances the effects of mesenchymal stromal cell-derived exosomes on ameliorating brain ischemic injury
- (2020) Qunwen Pan et al. Stem Cell Research & Therapy
- Astrocyte-derived exosome-transported microRNA-34c is neuroprotective against cerebral ischemia/reperfusion injury via TLR7 and the NF-κB/MAPK pathways
- (2020) Weicheng Wu et al. BRAIN RESEARCH BULLETIN
- Exosomes from miRNA‐126‐modified endothelial progenitor cells alleviate brain injury and promote functional recovery after stroke
- (2020) Jinju Wang et al. CNS Neuroscience & Therapeutics
- Design and Validation of a Human Brain Endothelial Microvessel-on-a-Chip Open Microfluidic Model Enabling Advanced Optical Imaging
- (2020) Mootaz M. Salman et al. Frontiers in Bioengineering and Biotechnology
- The Involvement of Exosomes in Glioblastoma Development, Diagnosis, Prognosis, and Treatment
- (2020) Adrian Bălașa et al. Brain Sciences
- Microglial vesicles improve post-stroke recovery by preventing immune cell senescence and favoring oligodendrogenesis
- (2020) Stefano Raffaele et al. MOLECULAR THERAPY
- Ischemic Cerebral Endothelial Cell–Derived Exosomes Promote Axonal Growth
- (2020) Yi Zhang et al. STROKE
- Exosome-Shuttled circSHOC2 from IPASs Regulates Neuronal Autophagy and Ameliorates Ischemic Brain Injury via the miR-7670-3p/SIRT1 Axis
- (2020) Wanghao Chen et al. Molecular Therapy-Nucleic Acids
- IL-4-polarized BV2 microglia cells promote angiogenesis by secreting exosomes
- (2019) Yan Tian et al. Advances in Clinical and Experimental Medicine
- Exosomes — beyond stem cells for restorative therapy in stroke and neurological injury
- (2019) Zheng Gang Zhang et al. Nature Reviews Neurology
- Astrocyte-derived exosomes suppress autophagy and ameliorate neuronal damage in experimental ischemic stroke
- (2019) Xiaoxi Pei et al. EXPERIMENTAL CELL RESEARCH
- Therapeutic strategy against ischemic stroke with the concept of neurovascular unit
- (2019) Tomohiko Ozaki et al. NEUROCHEMISTRY INTERNATIONAL
- Mesenchymal derived exosomes enhance recovery of motor function in a monkey model of cortical injury
- (2019) T.L. Moore et al. RESTORATIVE NEUROLOGY AND NEUROSCIENCE
- Exosome-shuttled miR-92b-3p from ischemic preconditioned astrocytes protects neurons against oxygen and glucose deprivation
- (2019) Lili Xu et al. BRAIN RESEARCH
- Circulating exosomes and their role in stroke
- (2019) Reza Jafarzadeh-Esfehani et al. CURRENT DRUG TARGETS
- Stimulus-dependent modifications in astrocyte-derived extracellular vesicle cargo regulate neuronal excitability
- (2019) Amrita Datta Chaudhuri et al. GLIA
- Exosomal miRNAs in central nervous system diseases: biomarkers, pathological mediators, protective factors and therapeutic agents
- (2019) Xiaohuan Xia et al. PROGRESS IN NEUROBIOLOGY
- Stem Cell-Derived Exosomes Protect Astrocyte Cultures From in vitro Ischemia and Decrease Injury as Post-stroke Intravenous Therapy
- (2019) Xiaoyun Sun et al. Frontiers in Cellular Neuroscience
- Exosomes derived from microRNA-138-5p-overexpressing bone marrow-derived mesenchymal stem cells confer neuroprotection to astrocytes following ischemic stroke via inhibition of LCN2
- (2019) Yiming Deng et al. Journal of Biological Engineering
- Adipose-derived mesenchymal stem cells attenuate ischemic brain injuries in rats by modulating miR-21-3p/MAT2B signaling transduction
- (2019) Chunshuang Li et al. CROATIAN MEDICAL JOURNAL
- MiR-126 Mediates Brain Endothelial Cell Exosome Treatment–Induced Neurorestorative Effects After Stroke in Type 2 Diabetes Mellitus Mice
- (2019) Poornima Venkat et al. STROKE
- Neurovascular Unit as a Source of Ischemic Stroke Biomarkers—Limitations of Experimental Studies and Perspectives for Clinical Application
- (2019) Aleksandra Steliga et al. Translational Stroke Research
- Extracellular vesicles from mesenchymal stem cells reduce microglial-mediated neuroinflammation after cortical injury in aged Rhesus monkeys
- (2019) Veronica Go et al. GeroScience
- Effects of neural stem cell‐derived extracellular vesicles on neuronal protection and functional recovery in the rat model of middle cerebral artery occlusion
- (2019) Marzieh Mahdavipour et al. CELL BIOCHEMISTRY AND FUNCTION
- Cerebral Organoids Repair Ischemic Stroke Brain Injury
- (2019) Shu-Na Wang et al. Translational Stroke Research
- Loading MiR-210 in Endothelial Progenitor Cells Derived Exosomes Boosts Their Beneficial Effects on Hypoxia/Reoxygeneation-Injured Human Endothelial Cells via Protecting Mitochondrial Function
- (2018) Xiaotang Ma et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Exosomes from MiR-30d-5p-ADSCs Reverse Acute Ischemic Stroke-Induced, Autophagy-Mediated Brain Injury by Promoting M2 Microglial/Macrophage Polarization
- (2018) Mei Jiang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Diagnosis of Hyperacute and Acute Ischaemic Stroke: The Potential Utility of Exosomal MicroRNA-21-5p and MicroRNA-30a-5p
- (2018) Wei Wang et al. CEREBROVASCULAR DISEASES
- Plasma Exosomal miR-422a and miR-125b-2-3p Serve as Biomarkers for Ischemic Stroke
- (2018) Dong-Bin Li et al. CURRENT NEUROVASCULAR RESEARCH
- Exosomes Secreted by Adipose-Derived Stem Cells Contribute to Angiogenesis of Brain Microvascular Endothelial Cells Following Oxygen–Glucose Deprivation In Vitro Through MicroRNA-181b/TRPM7 Axis
- (2018) Yujia Yang et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Global Burden of Stroke
- (2018) Mira Katan et al. SEMINARS IN NEUROLOGY
- Human Neural Stem Cell Extracellular Vesicles Improve Recovery in a Porcine Model of Ischemic Stroke
- (2018) Robin L. Webb et al. STROKE
- Tissue Engineering 3D Neurovascular Units: A Biomaterials and Bioprinting Perspective
- (2018) Geoffrey Potjewyd et al. TRENDS IN BIOTECHNOLOGY
- Extracellular Vesicles: Multimodal Envoys in Neural Maintenance and Repair
- (2018) Mea M. Holm et al. TRENDS IN NEUROSCIENCES
- Exosomes derived from PEDF modified adipose-derived mesenchymal stem cells ameliorate cerebral ischemia-reperfusion injury by regulation of autophagy and apoptosis
- (2018) Xiao Huang et al. EXPERIMENTAL CELL RESEARCH
- Bone marrow-derived mesenchymal stem cells-derived exosomes prevent oligodendrocyte apoptosis through exosomal miR-134 by targeting caspase-8
- (2018) Yilei Xiao et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Astrocyte-Derived Exosomes Treated With a Semaphorin 3A Inhibitor Enhance Stroke Recovery via Prostaglandin D 2 Synthase
- (2018) Kenichiro Hira et al. STROKE
- Role of Exosomes as a Treatment and Potential Biomarker for Stroke
- (2018) Laura Otero-Ortega et al. Translational Stroke Research
- Increased serum exosomal miR-134 expression in the acute ischemic stroke patients
- (2018) Jingxia Zhou et al. BMC Neurology
- Application of Mesenchymal Stem Cell-Derived Extracellular Vesicles for Stroke: Biodistribution and MicroRNA Study
- (2018) Gyeong Joon Moon et al. Translational Stroke Research
- Multicellular Crosstalk Between Exosomes and the Neurovascular Unit After Cerebral Ischemia. Therapeutic Implications
- (2018) Ana-Maria Zagrean et al. Frontiers in Neuroscience
- Endothelial cell-derived exosomes protect SH-SY5Y nerve cells against ischemia/reperfusion injury
- (2017) Bing Xiao et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Neural stem cell therapy for neurodegenerative disorders: The role of neurotrophic support
- (2017) Samuel E. Marsh et al. NEUROCHEMISTRY INTERNATIONAL
- The biphasic function of microglia in ischemic stroke
- (2017) Yuanyuan Ma et al. PROGRESS IN NEUROBIOLOGY
- Inflammatory Stroke Extracellular Vesicles Induce Macrophage Activation
- (2017) Yvonne Couch et al. STROKE
- MicroRNA-17–92 Cluster in Exosomes Enhance Neuroplasticity and Functional Recovery After Stroke in Rats
- (2017) Hongqi Xin et al. STROKE
- MicroRNA-9 Couples Brain Neurogenesis and Angiogenesis
- (2017) Romain Madelaine et al. Cell Reports
- Human Neural Stem Cell Extracellular Vesicles Improve Tissue and Functional Recovery in the Murine Thromboembolic Stroke Model
- (2017) Robin L. Webb et al. Translational Stroke Research
- Increased Circulating Exosomal miRNA-223 Is Associated with Acute Ischemic Stroke
- (2017) Yajing Chen et al. Frontiers in Neurology
- Distinct repertoires of microRNAs present in mouse astrocytes compared to astrocyte-secreted exosomes
- (2017) Ana Jovičić et al. PLoS One
- MALAT1 in human adipose stem cells modulates survival and alternative splicing of PKCδII in HT22 cells
- (2016) Ghattas El Bassit et al. ENDOCRINOLOGY
- Ischemic stroke outcome: A review of the influence of post-stroke complications within the different scenarios of stroke care
- (2016) Alejandro Bustamante et al. European Journal of Internal Medicine
- Improvement of neuronal cell survival by astrocyte-derived exosomes under hypoxic and ischemic conditions depends on prion protein
- (2016) Kathrin Guitart et al. GLIA
- Exosomes in stroke pathogenesis and therapy
- (2016) Zheng Gang Zhang et al. JOURNAL OF CLINICAL INVESTIGATION
- Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation
- (2016) Ángel Chamorro et al. LANCET NEUROLOGY
- Exosomes Derived from Mesenchymal Stromal Cells Promote Axonal Growth of Cortical Neurons
- (2016) Yi Zhang et al. MOLECULAR NEUROBIOLOGY
- Circulating MicroRNAs as Novel Biomarkers of Stenosis Progression in Asymptomatic Carotid Stenosis
- (2016) Sandra Dolz et al. STROKE
- Astrocytes: Key Regulators of Neuroinflammation
- (2016) Emanuela Colombo et al. TRENDS IN IMMUNOLOGY
- Increased Brain-Specific MiR-9 and MiR-124 in the Serum Exosomes of Acute Ischemic Stroke Patients
- (2016) Qiuhong Ji et al. PLoS One
- MSCs: The Sentinel and Safe-Guards of Injury
- (2015) Arnold I. Caplan JOURNAL OF CELLULAR PHYSIOLOGY
- Driving the Hypoxia-Inducible Pathway in Human Pericytes Promotes Vascular Density in an Exosome-Dependent Manner
- (2015) Jamie N. Mayo et al. MICROCIRCULATION
- Cerebral Ischemic Preconditioning: the Road So Far…
- (2015) Thushara Vijayakumar N et al. MOLECULAR NEUROBIOLOGY
- Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases
- (2015) Yu Tang et al. MOLECULAR NEUROBIOLOGY
- Targeting brain microvascular endothelial cells: a therapeutic approach to neuroprotection against stroke
- (2015) Qi-jin Yu et al. Neural Regeneration Research
- EVpedia: A community web resource for prokaryotic and eukaryotic extracellular vesicles research
- (2015) Dae-Kyum Kim et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- An updated role of microRNA-124 in central nervous system disorders: a review
- (2015) Yang Sun et al. Frontiers in Cellular Neuroscience
- Extracellular Vesicles Improve Post-Stroke Neuroregeneration and Prevent Postischemic Immunosuppression
- (2015) Thorsten R. Doeppner et al. Stem Cells Translational Medicine
- The neurovascular unit - concept review
- (2014) V. Muoio et al. Acta Physiologica
- To be or not to be, the level of autophagy is the question: Dual roles of autophagy in the survival response to starvation
- (2014) Chanhee Kang et al. Autophagy
- A comprehensive overview of exosomes as drug delivery vehicles — Endogenous nanocarriers for targeted cancer therapy
- (2014) Kasper Bendix Johnsen et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Multifaceted effects of oligodendroglial exosomes on neurons: impact on neuronal firing rate, signal transduction and gene regulation
- (2014) D. Frohlich et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Protection after stroke: cellular effectors of neurovascular unit integrity
- (2014) Rafael Andres Posada-Duque et al. Frontiers in Cellular Neuroscience
- Systemic Administration of Exosomes Released from Mesenchymal Stromal Cells Promote Functional Recovery and Neurovascular Plasticity After Stroke in Rats
- (2013) Hongqi Xin et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Exosomes: Mediators of Neurodegeneration, Neuroprotection and Therapeutics
- (2013) Anuradha Kalani et al. MOLECULAR NEUROBIOLOGY
- MiR-133b Promotes Neural Plasticity and Functional Recovery After Treatment of Stroke with Multipotent Mesenchymal Stromal Cells in Rats Via Transfer of Exosome-Enriched Extracellular Particles
- (2013) Hongqi Xin et al. STEM CELLS
- An Updated Definition of Stroke for the 21st Century
- (2013) Ralph L. Sacco et al. STROKE
- Extracellular vesicles as mediators of neuron-glia communication
- (2013) Carsten Frühbeis et al. Frontiers in Cellular Neuroscience
- Effects of intravenous administration of allogenic bone marrow- and adipose tissue-derived mesenchymal stem cells on functional recovery and brain repair markers in experimental ischemic stroke
- (2013) María Gutiérrez-Fernández et al. Stem Cell Research & Therapy
- Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte–Neuron Communication
- (2013) Carsten Frühbeis et al. PLOS BIOLOGY
- Brain-Immune Interactions and Ischemic Stroke
- (2012) Costantino Iadecola ARCHIVES OF NEUROLOGY
- Exosome-Mediated Transfer of miR-133b from Multipotent Mesenchymal Stromal Cells to Neural Cells Contributes to Neurite Outgrowth
- (2012) Hongqi Xin et al. STEM CELLS
- Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation
- (2012) Hina Kalra et al. PLOS BIOLOGY
- Synapsin I Is an Oligomannose-Carrying Glycoprotein, Acts As an Oligomannose-Binding Lectin, and Promotes Neurite Outgrowth and Neuronal Survival When Released via Glia-Derived Exosomes
- (2011) S. Wang et al. JOURNAL OF NEUROSCIENCE
- ExoCarta 2012: database of exosomal proteins, RNA and lipids
- (2011) S. Mathivanan et al. NUCLEIC ACIDS RESEARCH
- Release of exosomes from differentiated neurons and its regulation by synaptic glutamatergic activity
- (2010) Gaelle Lachenal et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- A novel pathway regulates memory and plasticity via SIRT1 and miR-134
- (2010) Jun Gao et al. NATURE
- Targeting the Ischemic Penumbra
- (2010) P. Ramos-Cabrer et al. STROKE
- MicroRNAs in brain development and physiology
- (2009) Marion Coolen et al. CURRENT OPINION IN NEUROBIOLOGY
- Neurorestorative therapies for stroke: underlying mechanisms and translation to the clinic
- (2009) Zheng Gang Zhang et al. LANCET NEUROLOGY
- ExoCarta: A compendium of exosomal proteins and RNA
- (2009) Suresh Mathivanan et al. PROTEOMICS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now