Glial Cells: Role of the Immune Response in Ischemic Stroke

Interleukin-17A-mediated alleviation of cortical astrocyte ischemic injuries affected the neurological outcome of mice with ischemic stroke

(2019) Qingqing Dai et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Preventative, but not post-stroke, inhibition of CD36 attenuates brain swelling in hyperlipidemic stroke

(2019) Eunhee Kim et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

T-Regulatory Cells Confer Increased Myelination and Stem Cell Activity after Stroke-Induced White Matter Injury

(2019) Sydney Zarriello et al.   Journal of Clinical Medicine

The interleukin-4/PPARγ signaling axis promotes oligodendrocyte differentiation and remyelination after brain injury

(2019) Qingxiu Zhang et al.   PLOS BIOLOGY

The active contribution of OPCs to neuroinflammation is mediated by LRP1

(2019) Anthony Fernández-Castañeda et al.   ACTA NEUROPATHOLOGICA

Upregulated microRNA‐31 inhibits oxidative stress‐induced neuronal injury through the JAK/STAT3 pathway by binding to PKD1 in mice with ischemic stroke

(2019) Jie Li et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration

(2019) Amit U. Joshi et al.   NATURE NEUROSCIENCE

Immune cell modulation of oligodendrocyte lineage cells

(2019) Emily P. Harrington et al.   NEUROSCIENCE LETTERS

Interleukin 15 blockade protects the brain from cerebral ischemia-reperfusion injury

(2018) Gilbert Aaron Lee et al.   BRAIN BEHAVIOR AND IMMUNITY

Enriched environment promotes post-stroke neurogenesis through NF-κB-mediated secretion of IL-17A from astrocytes

(2018) Yujing Zhang et al.   BRAIN RESEARCH

Enriched housing promotes post-stroke neurogenesis through calpain 1-STAT3/HIF-1α/VEGF signaling

(2018) Xiaoying Wu et al.   BRAIN RESEARCH BULLETIN

RGMa mediates reactive astrogliosis and glial scar formation through TGFβ1/Smad2/3 signaling after stroke

(2018) Rongrong Zhang et al.   CELL DEATH AND DIFFERENTIATION

Interferon regulatory factor 4/5 signaling impacts on microglial activation after ischemic stroke in mice

(2018) Abdullah Al Mamun et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease

(2018) Seung Pil Yun et al.   NATURE MEDICINE

Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion

(2018) Yubin Huang et al.   NATURE NEUROSCIENCE

Mechanisms of demyelination and remyelination in the young and aged brain following white matter stroke

(2018) Miguel Alejandro Marin et al.   NEUROBIOLOGY OF DISEASE

TIGAR inhibits ischemia/reperfusion-induced inflammatory response of astrocytes

(2018) Jieyu Chen et al.   NEUROPHARMACOLOGY

Astrocyte activation and reactive gliosis—A new target in stroke?

(2018) Milos Pekny et al.   NEUROSCIENCE LETTERS

Functional dissection of astrocyte-secreted proteins: Implications in brain health and diseases

(2018) Mithilesh Kumar Jha et al.   PROGRESS IN NEUROBIOLOGY

Blood-brain barrier dysfunction and recovery after ischemic stroke

(2018) Xiaoyan Jiang et al.   PROGRESS IN NEUROBIOLOGY

Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development

(2018) Ilia D. Vainchtein et al.   SCIENCE

Targeted complement inhibition salvages stressed neurons and inhibits neuroinflammation after stroke in mice

(2018) Ali Alawieh et al.   Science Translational Medicine

Brain Ischemia Induces Diversified Neuroantigen-Specific T-Cell Responses That Exacerbate Brain Injury

(2018) Wei-Na Jin et al.   STROKE

Immunosignals of Oligodendrocyte Markers and Myelin-Associated Proteins Are Critically Affected after Experimental Stroke in Wild-Type and Alzheimer Modeling Mice of Different Ages

(2018) Dominik Michalski et al.   Frontiers in Cellular Neuroscience

Experimental ischemic stroke induces long-term T cell activation in the brain

(2018) Luokun Xie et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Microglia in neurodegeneration

(2018) Suzanne Hickman et al.   NATURE NEUROSCIENCE

Apoptosis Signal-regulating Kinase 1 Silencing on Astroglial Inflammasomes in an Experimental Model of Ischemic Stroke

(2018) So Yeong Cheon et al.   NEUROSCIENCE

Pivotal role of innate myeloid cells in cerebral post-ischemic sterile inflammation

(2018) Jun Tsuyama et al.   Seminars in Immunopathology

Post-stroke inflammation—target or tool for therapy?

(2018) Kate Lykke Lambertsen et al.   ACTA NEUROPATHOLOGICA

Microglial cell loss after ischemic stroke favors brain neutrophil accumulation

(2018) Amaia Otxoa-de-Amezaga et al.   ACTA NEUROPATHOLOGICA

Activated T cells induce proliferation of oligodendrocyte progenitor cells via release of vascular endothelial cell growth factor-A

(2018) Elliot H. Choi et al.   GLIA

Stroke target identification guided by astrocyte transcriptome analysis

(2018) Cordula Rakers et al.   GLIA

Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery

(2018) Minako Ito et al.   NATURE

Glia as architects of central nervous system formation and function

(2018) Nicola J. Allen et al.   SCIENCE

Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells

(2018) Harald Lund et al.   Nature Communications

Reactive Astrocytes: Production, Function, and Therapeutic Potential

(2017) Shane A. Liddelow et al.   IMMUNITY

Microglia and Monocytes/Macrophages Polarization Reveal Novel Therapeutic Mechanism against Stroke

(2017) Masato Kanazawa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Stroke

(2017) Graeme J Hankey   LANCET

P2Y1 receptor antagonists mitigate oxygen and glucose deprivation‑induced astrocyte injury

(2017) Hui Guo et al.   Molecular Medicine Reports

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

The biphasic function of microglia in ischemic stroke

(2017) Yuanyuan Ma et al.   PROGRESS IN NEUROBIOLOGY

Author Correction: Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway

(2017) Yosuke M. Morizawa et al.   Nature Communications

A Combination of Three Repurposed Drugs Administered at Reperfusion as a Promising Therapy for Postischemic Brain Injury

(2017) I-Chen Yu et al.   Translational Stroke Research

Toll-like Receptor 2: A Novel Therapeutic Target for Ischemic White Matter Injury and Oligodendrocyte Death

(2017) Jun Young Choi et al.   Experimental Neurobiology

Transcriptome Analysis Reveals Neuroprotective aspects of Human Reactive Astrocytes induced by Interleukin 1β

(2017) Daniel Boon Loong Teh et al.   Scientific Reports

NLRP2 is highly expressed in a mouse model of ischemic stroke

(2016) Xia Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Complement peptide C3a stimulates neural plasticity after experimental brain ischaemia

(2016) Anna Stokowska et al.   BRAIN

Microglia in central nervous system repair after injury

(2016) Xuemei Jin et al.   JOURNAL OF BIOCHEMISTRY

The search for true numbers of neurons and glial cells in the human brain: A review of 150 years of cell counting

(2016) Christopher S. von Bartheld et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Sinomenine activates astrocytic dopamine D2 receptors and alleviates neuroinflammatory injury via the CRYAB/STAT3 pathway after ischemic stroke in mice

(2016) Jing Qiu et al.   Journal of Neuroinflammation

Complement component C3a plays a critical role in endothelial activation and leukocyte recruitment into the brain

(2016) Fengjiao Wu et al.   Journal of Neuroinflammation

Megf10 Is a Receptor for C1Q That Mediates Clearance of Apoptotic Cells by Astrocytes

(2016) Tal Iram et al.   JOURNAL OF NEUROSCIENCE

Astrocytic GAP43 Induced by the TLR4/NF- B/STAT3 Axis Attenuates Astrogliosis-Mediated Microglial Activation and Neurotoxicity

(2016) C.-C. Hung et al.   JOURNAL OF NEUROSCIENCE

Stroke induces specific alteration of T memory compartment controlling auto-reactive CNS antigen-specific T cell responses

(2016) Juliane Klehmet et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation

(2016) Ángel Chamorro et al.   LANCET NEUROLOGY

A polarizing question: do M1 and M2 microglia exist?

(2016) Richard M Ransohoff   NATURE NEUROSCIENCE

Reactive astrocytes and therapeutic potential in focal ischemic stroke

(2016) Gourav Roy Choudhury et al.   NEUROBIOLOGY OF DISEASE

Blood/Brain Biomarkers of Inflammation After Stroke and Their Association With Outcome: From C-Reactive Protein to Damage-Associated Molecular Patterns

(2016) Alejandro Bustamante et al.   Neurotherapeutics

Astrocytes: Integrative Regulators of Neuroinflammation in Stroke and Other Neurological Diseases

(2016) Egle Cekanaviciute et al.   Neurotherapeutics

Astrocyte-derived interleukin-15 exacerbates ischemic brain injury via propagation of cellular immunity

(2016) Minshu Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astrocytes, therapeutic targets for neuroprotection and neurorestoration in ischemic stroke

(2016) Zhongwu Liu et al.   PROGRESS IN NEUROBIOLOGY

Functions and mechanisms of microglia/macrophages in neuroinflammation and neurogenesis after stroke

(2016) Xiao-Yi Xiong et al.   PROGRESS IN NEUROBIOLOGY

Non-Smad Signaling Pathways of the TGF-β Family

(2016) Ying E. Zhang   Cold Spring Harbor Perspectives in Biology

Critical role of astrocytic interleukin-17 A in post-stroke survival and neuronal differentiation of neural precursor cells in adult mice

(2016) Y Lin et al.   Cell Death & Disease

Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke

(2016) Gergely Szalay et al.   Nature Communications

Mechanisms of Axonal Damage and Repair after Central Nervous System Injury

(2016) Naohiro Egawa et al.   Translational Stroke Research

Spontaneous and Therapeutic-Induced Mechanisms of Functional Recovery After Stroke

(2016) Jessica M. Cassidy et al.   Translational Stroke Research

Astrocytes: a central element in neurological diseases

(2015) Milos Pekny et al.   ACTA NEUROPATHOLOGICA

Microglia–blood vessel interactions: a double-edged sword in brain pathologies

(2015) Nevenka Dudvarski Stankovic et al.   ACTA NEUROPATHOLOGICA

Enhanced phasic GABA inhibition during the repair phase of stroke: a novel therapeutic target

(2015) Takeshi Hiu et al.   BRAIN

Demyelination as a rational therapeutic target for ischemic or traumatic brain injury

(2015) Hong Shi et al.   EXPERIMENTAL NEUROLOGY

Salipiger nanhaiensis sp. nov., a bacterium isolated from deep sea water

(2015) Xiaofeng Dai et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Determining the role of IL-4 induced neuroinflammation in microglial activity and amyloid-β using BV2 microglial cells and APP/PS1 transgenic mice

(2015) Clare H Latta et al.   Journal of Neuroinflammation

Functional differences between microglia and monocytes after ischemic stroke

(2015) Rodney M. Ritzel et al.   Journal of Neuroinflammation

Alteration in rectification of potassium channels in perinatal hypoxia ischemia brain damage

(2015) Penghui Chen et al.   JOURNAL OF NEUROPHYSIOLOGY

Blocking Stroke-Induced Immunodeficiency Increases CNS Antigen-Specific Autoreactivity But Does Not Worsen Functional Outcome after Experimental Stroke

(2015) C. Romer et al.   JOURNAL OF NEUROSCIENCE

Complement Peptide C3a Promotes Astrocyte Survival in Response to Ischemic Stress

(2015) Noriko Shinjyo et al.   MOLECULAR NEUROBIOLOGY

Elusive roles for reactive astrocytes in neurodegenerative diseases

(2015) Lucile Ben Haim et al.   Frontiers in Cellular Neuroscience

The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia

(2015) Han Seok Koh et al.   Nature Communications

Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation

(2015) Miguel Angel Burguillos et al.   Cell Reports

CXCL12Gene Therapy Ameliorates Ischemia-Induced White Matter Injury in Mouse Brain

(2015) Yaning Li et al.   Stem Cells Translational Medicine

Rational modulation of the innate immune system for neuroprotection in ischemic stroke

(2015) Diana Amantea et al.   Frontiers in Neuroscience

Perivascular microglia promote blood vessel disintegration in the ischemic penumbra

(2014) Valérie Jolivel et al.   ACTA NEUROPATHOLOGICA

Dynamic structural remodelling of microglia in health and disease: A review of the models, the signals and the mechanisms

(2014) F. Rohan Walker et al.   BRAIN BEHAVIOR AND IMMUNITY

Oligodendrocyte Pathophysiology and Treatment Strategies in Cerebral Ischemia

(2014) Gabriella Mifsud et al.   CNS Neuroscience & Therapeutics

Toll-like receptor 4 modulates cell migration and cortical neurogenesis after focal cerebral ischemia

(2014) Ana Moraga et al.   FASEB JOURNAL

IL-17A activates ERK1/2 and enhances differentiation of oligodendrocyte progenitor cells

(2014) Jane M. Rodgers et al.   GLIA

Astrocytic transforming growth factor-beta signaling reduces subacute neuroinflammation after stroke in mice

(2014) Egle Cekanaviciute et al.   GLIA

Activation and Regulation of Cellular Inflammasomes: Gaps in Our Knowledge for Central Nervous System Injury

(2014) Juan Pablo de Rivero Vaccari et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neurogenesis and Inflammation after Ischemic Stroke: What is Known and Where We Go from Here

(2014) Matthew K Tobin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuroinflammation and M2 microglia: the good, the bad, and the inflamed

(2014) Jonathan D Cherry et al.   Journal of Neuroinflammation

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Microglial phagocytosis of live neurons

(2014) Guy C. Brown et al.   NATURE REVIEWS NEUROSCIENCE

Nogo-A: Multiple Roles in CNS Development, Maintenance, and Disease

(2014) A. Schmandke et al.   NEUROSCIENTIST

Peroxiredoxin 5 (PRX5) Is Correlated Inversely to Systemic Markers of Inflammation in Acute Stroke

(2014) Allison Kunze et al.   STROKE

The impact of microglial activation on blood-brain barrier in brain diseases

(2014) Anna Carolina Carvalho da Fonseca et al.   Frontiers in Cellular Neuroscience

Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro

(2013) Vibol Chhor et al.   BRAIN BEHAVIOR AND IMMUNITY

In Vivo Direct Reprogramming of Reactive Glial Cells into Functional Neurons after Brain Injury and in an Alzheimer’s Disease Model

(2013) Ziyuan Guo et al.   Cell Stem Cell

Crosstalk between cerebral endothelium and oligodendrocyte

(2013) Nobukazu Miyamoto et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Interferon Regulatory Factor 4 Regulates Obesity-Induced Inflammation Through Regulation of Adipose Tissue Macrophage Polarization

(2013) J. Eguchi et al.   DIABETES

SMND-309, a novel derivative of salvianolic acid B, protects rat brains ischemia and reperfusion injury by targeting the JAK2/STAT3 pathway

(2013) Haibo Zhu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Receptor for complement peptide C3a: a therapeutic target for neonatal hypoxic-ischemic brain injury

(2013) Katarina Järlestedt et al.   FASEB JOURNAL

Human astrocytes express a novel NLRP2 inflammasome

(2013) Julia Minkiewicz et al.   GLIA

P2Y1R-Initiated, IP3R-Dependent Stimulation of Astrocyte Mitochondrial Metabolism Reduces and Partially Reverses Ischemic Neuronal Damage in Mouse

(2013) Wei Zheng et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Netrin-1 Overexpression Promotes White Matter Repairing and Remodeling after Focal Cerebral Ischemia in Mice

(2013) Xiaosong He et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Oligodendrocyte precursors induce early blood-brain barrier opening after white matter injury

(2013) Ji Hae Seo et al.   JOURNAL OF CLINICAL INVESTIGATION

BNIP3 mediates pre-myelinating oligodendrocyte cell death in hypoxia and ischemia

(2013) Chengren Li et al.   JOURNAL OF NEUROCHEMISTRY

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

(2013) Veronique E Miron et al.   NATURE NEUROSCIENCE

Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain

(2013) Ethan G Hughes et al.   NATURE NEUROSCIENCE

Microglia Actively Regulate the Number of Functional Synapses

(2013) Kyungmin Ji et al.   PLoS One

Phagocytosis executes delayed neuronal death after focal brain ischemia

(2013) J. J. Neher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oligodendrogenesis after cerebral ischemia

(2013) Ruilan Zhang et al.   Frontiers in Cellular Neuroscience

Genetic deletion of CD36 enhances injury after acute neonatal stroke

(2012) Moon-Sook Woo et al.   ANNALS OF NEUROLOGY

Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke

(2012) M. Gelderblom et al.   BLOOD

Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature

(2012) C. Kleinschnitz et al.   BLOOD

Generation of complement component C5a by ischemic neurons promotes neuronal apoptosis

(2012) Dale Pavlovski et al.   FASEB JOURNAL

Comparison of polarization properties of human adult microglia and blood-derived macrophages

(2012) Bryce A. Durafourt et al.   GLIA

Inflammatory Cytokines in Experimental and Human Stroke

(2012) Kate Lykke Lambertsen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

CD36 is Involved in Astrocyte Activation and Astroglial Scar Formation

(2012) Yi Bao et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The cytokine tumor necrosis factor-like weak inducer of apoptosis and its receptor fibroblast growth factor-inducible 14 have a neuroprotective effect in the central nervous system

(2012) Ramiro Echeverry et al.   Journal of Neuroinflammation

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain

(2012) Takashi Shichita et al.   NATURE MEDICINE

Neuroinflammatory phenotype in early Alzheimer's disease

(2012) Tiffany L. Sudduth et al.   NEUROBIOLOGY OF AGING

Complement Inhibition Promotes Endogenous Neurogenesis and Sustained Anti-Inflammatory Neuroprotection following Reperfused Stroke

(2012) Andrew F. Ducruet et al.   PLoS One

Astrocytic high-mobility group box 1 promotes endothelial progenitor cell-mediated neurovascular remodeling during stroke recovery

(2012) K. Hayakawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myelin Loss Associated With Neuroinflammation in Hypertensive Rats

(2012) Fakhreya Y. Jalal et al.   STROKE

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

(2012) Xiaoming Hu et al.   STROKE

Vascular Endothelial Growth Factors A and C are Induced in the SVZ Following Neonatal Hypoxia–Ischemia and Exert Different Effects on Neonatal Glial Progenitors

(2012) Jennifer M. Bain et al.   Translational Stroke Research

Reactive Oxygen Species Scavenger Inhibits STAT3 Activation After Transient Focal Cerebral Ischemia–Reperfusion Injury in Rats

(2011) Chong Lei et al.   ANESTHESIA AND ANALGESIA

Heart Disease and Stroke Statistics—2012 Update

(2011) et al.   CIRCULATION

Astrocytic P2Y1 receptor is involved in the regulation of cytokine/chemokine transcription and cerebral damage in a rat model of cerebral ischemia

(2011) Kazuya Kuboyama et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Inhibition of Microglial Phagocytosis Is Sufficient To Prevent Inflammatory Neuronal Death

(2011) J. J. Neher et al.   JOURNAL OF IMMUNOLOGY

Temporal pattern of expression and colocalization of microglia/macrophage phenotype markers following brain ischemic injury in mice

(2011) Carlo Perego et al.   Journal of Neuroinflammation

Tissue inhibitor of metalloproteinases-3 mediates the death of immature oligodendrocytes via TNF-α/TACE in focal cerebral ischemia in mice

(2011) Yi Yang et al.   Journal of Neuroinflammation

Myelin specific cells infiltrate MCAO lesions and exacerbate stroke severity

(2011) Xuefang Ren et al.   METABOLIC BRAIN DISEASE

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Heterogeneity of CNS myeloid cells and their roles in neurodegeneration

(2011) Marco Prinz et al.   NATURE NEUROSCIENCE

Neuroprotection by Interleukin-6 Is Mediated by Signal Transducer and Activator of Transcription 3 and Antioxidative Signaling in Ischemic Stroke

(2011) Joo Eun Jung et al.   STROKE

Proliferating Reactive Astrocytes Are Regulated by Notch-1 in the Peri-Infarct Area After Stroke

(2011) Issei S. Shimada et al.   STROKE

Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFκB signaling, MAPK, and Jak1/Stat1 pathways

(2010) Roser Gorina et al.   GLIA

Astrocyte-Restricted Ablation of Interleukin-17-Induced Act1-Mediated Signaling Ameliorates Autoimmune Encephalomyelitis

(2010) Zizhen Kang et al.   IMMUNITY

The Interaction between Tumor Necrosis Factor-Like Weak Inducer of Apoptosis and its Receptor Fibroblast Growth Factor-Inducible 14 Promotes the Recruitment of Neutrophils into the Ischemic Brain

(2010) Woldeab B Haile et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

HMBG1 Mediates Ischemia—Reperfusion Injury by TRIF-Adaptor Independent Toll-Like Receptor 4 Signaling

(2010) Qing-Wu Yang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

TGFβ signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke

(2010) Kristian P Doyle et al.   Journal of Neuroinflammation

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease

(2010) Martin Fuhrmann et al.   NATURE NEUROSCIENCE

Tumor necrosis factor-like weak inducer of apoptosis and fibroblast growth factor-inducible 14 mediate cerebral ischemia-induced poly(ADP-ribose) polymerase-1 activation and neuronal death

(2010) W.B. Haile et al.   NEUROSCIENCE

Toll-like receptor 4 (TLR4), but not TLR3 or TLR9, knock-out mice have neuroprotective effects against focal cerebral ischemia

(2010) K. Hyakkoku et al.   NEUROSCIENCE

Microglial activation in stroke: Therapeutic targets

(2010) Midori A. Yenari et al.   Neurotherapeutics

Purinergic Receptor Stimulation Reduces Cytotoxic Edema and Brain Infarcts in Mouse Induced by Photothrombosis by Energizing Glial Mitochondria

(2010) Wei Zheng et al.   PLoS One

Regulation of Oligodendrocyte Differentiation and Myelination

(2010) B. Emery   SCIENCE

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

High-Mobility Group Box 1 Promotes Metalloproteinase-9 Upregulation Through Toll-Like Receptor 4 After Cerebral Ischemia

(2010) Jianhua Qiu et al.   STROKE

Inflammation, plasticity and real-time imaging after cerebral ischemia

(2009) Jasna Kriz et al.   ACTA NEUROPATHOLOGICA

Inactivation of astroglial NF-κB promotes survival of retinal neurons following ischemic injury

(2009) Galina Dvoriantchikova et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

An Oligovascular Niche: Cerebral Endothelial Cells Promote the Survival and Proliferation of Oligodendrocyte Precursor Cells

(2009) K. Arai et al.   JOURNAL OF NEUROSCIENCE

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Neurorestorative therapies for stroke: underlying mechanisms and translation to the clinic

(2009) Zheng Gang Zhang et al.   LANCET NEUROLOGY

Periventricular white matter damage in the hypoxic neonatal brain: Role of microglial cells

(2009) C. Kaur et al.   PROGRESS IN NEUROBIOLOGY

Amoeboid Microglia in the Periventricular White Matter Induce Oligodendrocyte Damage through Expression of Proinflammatory Cytokines via MAP Kinase Signaling Pathway in Hypoxic Neonatal Rats

(2008) YiYu Deng et al.   BRAIN PATHOLOGY

Functional Characterization of Murine Interferon Regulatory Factor 5 (IRF-5) and Its Role in the Innate Antiviral Response

(2008) Andrea Paun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The life, death, and replacement of oligodendrocytes in the adult CNS

(2008) Dana M. McTigue et al.   JOURNAL OF NEUROCHEMISTRY

Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice

(2008) Bettina H Clausen et al.   Journal of Neuroinflammation

Neuregulin-1/ErbB Signaling Serves Distinct Functions in Myelination of the Peripheral and Central Nervous System

(2008) Bastian G. Brinkmann et al.   NEURON

Inflammation and the neurovascular unit in the setting of focal cerebral ischemia

(2008) G.J. del Zoppo   NEUROSCIENCE

PROTECTIVE EFFECT OF C5A RECEPTOR INHIBITION AFTER MURINE REPERFUSED STROKE

(2008) Grace H. Kim et al.   NEUROSURGERY

Neocortical glial cell numbers in human brains

(2007) D.P. Pelvig et al.   NEUROBIOLOGY OF AGING