Mesenchymal derived exosomes enhance recovery of motor function in a monkey model of cortical injury

Exosomes derived from umbilical cord mesenchymal stem cells reduce microglia-mediated neuroinflammation in perinatal brain injury

(2019) Gierin Thomi et al.   Stem Cell Research & Therapy

Cell based therapy reduces secondary damage and increases extent of microglial activation following cortical injury

(2019) Mary E. Orczykowski et al.   BRAIN RESEARCH

Cell based therapy enhances activation of ventral premotor cortex to improve recovery following primary motor cortex injury

(2018) Mary E. Orczykowski et al.   EXPERIMENTAL NEUROLOGY

Exosome-mediated amplification of endogenous brain repair mechanisms and brain and systemic organ interaction in modulating neurological outcome after stroke

(2018) Poornima Venkat et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Multipotent mesenchymal stromal cell–derived exosomes improve functional recovery after experimental intracerebral hemorrhage in the rat

(2018) Yuxia Han et al.   JOURNAL OF NEUROSURGERY

Mesenchymal Stem Cell-Derived Exosomes Provide Neuroprotection and Improve Long-Term Neurologic Outcomes in a Swine Model of Traumatic Brain Injury and Hemorrhagic Shock

(2018) Aaron M Williams et al.   JOURNAL OF NEUROTRAUMA

Exosome Therapy for Stroke

(2018) Jieli Chen et al.   STROKE

Cell-Based and Exosome Therapy in Diabetic Stroke

(2018) Poornima Venkat et al.   Stem Cells Translational Medicine

The potential role of exosomes in the diagnosis and therapy of ischemic diseases

(2018) WENTING WANG et al.   CYTOTHERAPY

Post-stroke inflammation—target or tool for therapy?

(2018) Kate Lykke Lambertsen et al.   ACTA NEUROPATHOLOGICA

Evaluation of Long-Term Cryostorage of Brain Tissue Sections for Quantitative Histochemistry

(2017) Larissa I. Estrada et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Systemic administration of cell-free exosomes generated by human bone marrow derived mesenchymal stem cells cultured under 2D and 3D conditions improves functional recovery in rats after traumatic brain injury

(2017) Yanlu Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

Stem cell therapy for abrogating stroke-induced neuroinflammation and relevant secondary cell death mechanisms

(2017) Connor Stonesifer et al.   PROGRESS IN NEUROBIOLOGY

Mesenchymal Stem Cell-Derived Microvesicles Modulate Lipopolysaccharides-Induced Inflammatory Responses to Microglia Cells

(2017) Yarúa Jaimes et al.   STEM CELLS

Exosomes secreted by stem cells from human exfoliated deciduous teeth contribute to functional recovery after traumatic brain injury by shifting microglia M1/M2 polarization in rats

(2017) Ye Li et al.   Stem Cell Research & Therapy

Understanding the Mechanisms of Recovery and/or Compensation following Injury

(2017) Michael J. Hylin et al.   NEURAL PLASTICITY

How to Translate Time? The Temporal Aspect of Human and Rodent Biology

(2017) Denes V. Agoston   Frontiers in Neurology

Exosomes in stroke pathogenesis and therapy

(2016) Zheng Gang Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Exosomes Derived from Mesenchymal Stromal Cells Promote Axonal Growth of Cortical Neurons

(2016) Yi Zhang et al.   MOLECULAR NEUROBIOLOGY

Inflammation and Stroke: An Overview

(2016) Josef Anrather et al.   Neurotherapeutics

Inosine enhances recovery of grasp following cortical injury to the primary motor cortex of the rhesus monkey

(2016) Tara L. Moore et al.   RESTORATIVE NEUROLOGY AND NEUROSCIENCE

Differential and transferable modulatory effects of mesenchymal stromal cell-derived extracellular vesicles on T, B and NK cell functions

(2016) Mariano Di Trapani et al.   Scientific Reports

Emerging potential of exosomes and noncoding microRNAs for the treatment of neurological injury/diseases

(2015) Michael Chopp et al.   EXPERT OPINION ON EMERGING DRUGS

Effect of exosomes derived from multipluripotent mesenchymal stromal cells on functional recovery and neurovascular plasticity in rats after traumatic brain injury

(2015) Yanlu Zhang et al.   JOURNAL OF NEUROSURGERY

Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs

(2015) Donald G. Phinney et al.   Nature Communications

The Ischemic Environment Drives Microglia and Macrophage Function

(2015) Stefano Fumagalli et al.   Frontiers in Neurology

Exosomal Tumor MicroRNA Modulates Premetastatic Organ Cells

(2015) Sanyukta Rana et al.   NEOPLASIA

Post-ischemic inflammation regulates neural damage and protection

(2014) Takashi Shichita et al.   Frontiers in Cellular Neuroscience

Mesenchymal Stem Cells Expressing Brain-Derived Neurotrophic Factor Enhance Endogenous Neurogenesis in an Ischemic Stroke Model

(2014) Chang Hyun Jeong et al.   Biomed Research International

Exosomes from marrow stromal cells expressing miR-146b inhibit glioma growth

(2013) Mark Katakowski et al.   CANCER LETTERS

Neuronal Exosomal miRNA-dependent Translational Regulation of Astroglial Glutamate Transporter GLT1

(2013) Lydie Morel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systemic Administration of Exosomes Released from Mesenchymal Stromal Cells Promote Functional Recovery and Neurovascular Plasticity After Stroke in Rats

(2013) Hongqi Xin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Regulation of Postsynaptic Retrograde Signaling by Presynaptic Exosome Release

(2013) Ceren Korkut et al.   NEURON

Recovery of fine motor performance after ischemic damage to motor cortex is facilitated by cell therapy in the rhesus monkey

(2013) Tara L. Moore et al.   SOMATOSENSORY AND MOTOR RESEARCH

MiR-133b Promotes Neural Plasticity and Functional Recovery After Treatment of Stroke with Multipotent Mesenchymal Stromal Cells in Rats Via Transfer of Exosome-Enriched Extracellular Particles

(2013) Hongqi Xin et al.   STEM CELLS

Mesenchymal Stem Cells Secrete Immunologically Active Exosomes

(2013) Bin Zhang et al.   STEM CELLS AND DEVELOPMENT

The role of exosomes and microRNAs in senescence and aging

(2012) Dan Xu et al.   ADVANCED DRUG DELIVERY REVIEWS

Exosomes and microvesicles: extracellular vesicles for genetic information transfer and gene therapy

(2012) Y. Lee et al.   HUMAN MOLECULAR GENETICS

Exosome-Mediated Transfer of miR-133b from Multipotent Mesenchymal Stromal Cells to Neural Cells Contributes to Neurite Outgrowth

(2012) Hongqi Xin et al.   STEM CELLS

Axonal Outgrowth and Dendritic Plasticity in the Cortical Peri-Infarct Area After Experimental Stroke

(2012) Yuji Ueno et al.   STROKE

Recovery from ischemia in the middle-aged brain: a nonhuman primate model

(2011) Tara L. Moore et al.   NEUROBIOLOGY OF AGING

Erythropoietin Mediates Neurobehavioral Recovery and Neurovascular Remodeling Following Traumatic Brain Injury in Rats by Increasing Expression of Vascular Endothelial Growth Factor

(2011) Ye Xiong et al.   Translational Stroke Research

Bone Marrow Stromal Cells Enhance Inter- and Intracortical Axonal Connections after Ischemic Stroke in Adult Rats

(2010) Zhongwu Liu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Assessment of motor function of the hand in aged rhesus monkeys

(2010) Tara L. Moore et al.   SOMATOSENSORY AND MOTOR RESEARCH

The complexity of neurobiological processes in acute ischemic stroke

(2009) R. Brouns et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Exosomes – vesicular carriers for intercellular communication

(2009) Mikael Simons et al.   CURRENT OPINION IN CELL BIOLOGY

Inflammatory mechanisms in ischemic stroke: therapeutic approaches

(2009) Shaheen E Lakhan et al.   Journal of Translational Medicine

Gains in Upper Extremity Function After Stroke via Recovery or Compensation: Potential Differential Effects on Amount of Real-World Limb Use

(2009) Peter S. Lum et al.   Topics in Stroke Rehabilitation

Mechanisms Underlying Improved Recovery of Neurological Function After Stroke in the Rodent After Treatment With Neurorestorative Cell-Based Therapies

(2008) M. Chopp et al.   STROKE