MiR-126 Mediates Brain Endothelial Cell Exosome Treatment–Induced Neurorestorative Effects After Stroke in Type 2 Diabetes Mellitus Mice

Exosome-mediated amplification of endogenous brain repair mechanisms and brain and systemic organ interaction in modulating neurological outcome after stroke

(2018) Poornima Venkat et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Therapeutic potential of extracellular vesicles derived from human mesenchymal stem cells in a model of progressive multiple sclerosis

(2018) Fernando Laso-García et al.   PLoS One

Diabetes Mellitus Impairs White Matter Repair and Long-Term Functional Deficits After Cerebral Ischemia

(2018) Shubei Ma et al.   STROKE

Exosomes promote restoration after an experimental animal model of intracerebral hemorrhage

(2017) Laura Otero-Ortega et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Systemic administration of cell-free exosomes generated by human bone marrow derived mesenchymal stem cells cultured under 2D and 3D conditions improves functional recovery in rats after traumatic brain injury

(2017) Yanlu Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

Intranasal MSC-derived A1-exosomes ease inflammation, and prevent abnormal neurogenesis and memory dysfunction after status epilepticus

(2017) Qianfa Long et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

D-4F increases microRNA-124a and reduces neuroinflammation in diabetic stroke rats

(2017) Ruizhuo Ning et al.   Oncotarget

MiR-126 Affects Brain-Heart Interaction after Cerebral Ischemic Stroke

(2017) Jieli Chen et al.   Translational Stroke Research

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

(2016) Joanna Kowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MiR-126 Contributes to Human Umbilical Cord Blood Cell-Induced Neurorestorative Effects After Stroke in Type-2 Diabetic Mice

(2016) Jieli Chen et al.   STEM CELLS

Bone marrow-derived mesenchymal stem cells improve diabetes-induced cognitive impairment by exosome transfer into damaged neurons and astrocytes

(2016) Masako Nakano et al.   Scientific Reports

miR-126 promotes angiogenesis and attenuates inflammation after contusion spinal cord injury in rats

(2015) Jianzhong Hu et al.   BRAIN RESEARCH

MiR-21-5p and miR-126a-3p levels in plasma and circulating angiogenic cells: relationship with type 2 diabetes complications

(2015) Fabiola Olivieri et al.   Oncotarget

Effects of Focal Cerebral Ischemia on Exosomal Versus Serum miR126

(2015) Fan Chen et al.   Translational Stroke Research

Dynamic Biodistribution of Extracellular Vesicles in Vivo Using a Multimodal Imaging Reporter

(2014) Charles P. Lai et al.   ACS Nano

Improvement of functional recovery by chronic metformin treatment is associated with enhanced alternative activation of microglia/macrophages and increased angiogenesis and neurogenesis following experimental stroke

(2014) Qin Jin et al.   BRAIN BEHAVIOR AND IMMUNITY

The Role of Circulating MicroRNA-126 (miR-126): A Novel Biomarker for Screening Prediabetes and Newly Diagnosed Type 2 Diabetes Mellitus

(2014) Yang Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Exosomes/miRNAs as mediating cell-based therapy of stroke

(2014) Hongqi Xin et al.   Frontiers in Cellular Neuroscience

Endothelial Microparticle–Mediated Transfer of MicroRNA-126 Promotes Vascular Endothelial Cell Repair via SPRED1 and Is Abrogated in Glucose-Damaged Endothelial Microparticles

(2013) Felix Jansen et al.   CIRCULATION

The MicroRNA-17-92 Cluster Enhances Axonal Outgrowth in Embryonic Cortical Neurons

(2013) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Downregulation of microRNA-126 in endothelial progenitor cells from diabetes patients, impairs their functional properties, via target gene Spred-1

(2012) S. Meng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Transplantation of Mesenchymal Stem Cells Promotes an Alternative Pathway of Macrophage Activation and Functional Recovery after Spinal Cord Injury

(2012) Hideaki Nakajima et al.   JOURNAL OF NEUROTRAUMA

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

(2012) Xiaoming Hu et al.   STROKE

A long-term observation of olfactory ensheathing cells transplantation to repair white matter and functional recovery in a focal ischemia model in rat

(2010) Xianzhong Shi et al.   BRAIN RESEARCH

Diabetes Mellitus Reveals Its Micro-Signature

(2010) Romano Regazzi   CIRCULATION RESEARCH

Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes

(2010) Anna Zampetaki et al.   CIRCULATION RESEARCH

Comparison of Bone Marrow Stromal Cells Derived From Stroke and Normal Rats for Stroke Treatment

(2010) Alex Zacharek et al.   STROKE

White Matter Damage and the Effect of Matrix Metalloproteinases in Type 2 Diabetic Mice After Stroke

(2010) Jieli Chen et al.   STROKE

miR-126 Regulates Angiogenic Signaling and Vascular Integrity

(2008) Jason E. Fish et al.   DEVELOPMENTAL CELL

The Endothelial-Specific MicroRNA miR-126 Governs Vascular Integrity and Angiogenesis

(2008) Shusheng Wang et al.   DEVELOPMENTAL CELL

Alcohol-induced retrograde memory impairment in rats: prevention by caffeine

(2008) Michael J. Spinetta et al.   PSYCHOPHARMACOLOGY