Alterations in the gut microbiota contribute to cognitive impairment induced by the ketogenic diet and hypoxia

Ketogenic diet and fasting diet as Nutritional Approaches in Multiple Sclerosis (NAMS): protocol of a randomized controlled study

(2020) Lina Samira Bahr et al.   Trials

Gut microbiota mediates intermittent-fasting alleviation of diabetes-induced cognitive impairment

(2020) Zhigang Liu et al.   Nature Communications

Influence of the Mediterranean and Ketogenic Diets on Cognitive Status and Decline: A Narrative Review

(2020) Federica Vinciguerra et al.   Nutrients

Parkinson’s disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions

(2020) Federico Baldini et al.   BMC BIOLOGY

Priming of microglia with IFN ‐γ impairs adult hippocampal neurogenesis and leads to depression‐like behaviors and cognitive defects

(2020) Jinqiang Zhang et al.   GLIA

Alzheimer’s Disease: The Link Between Amyloid-β and Neurovascular Dysfunction

(2020) Ernesto Solis et al.   JOURNAL OF ALZHEIMERS DISEASE

A HIF1a-Dependent Pro-Oxidant State Disrupts Synaptic Plasticity and Impairs Spatial Memory in Response to Intermittent Hypoxia

(2020) Alejandra Arias-Cavieres et al.   eNeuro

Trends in the Risk of Cognitive Impairment in the United States, 1996–2014

(2020) Jo Mhairi Hale et al.   EPIDEMIOLOGY

Gut microbiota composition in children with Obstructive Sleep Apnoea Syndrome: a pilot study

(2020) Francesco Valentini et al.   SLEEP MEDICINE

Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients

(2020) Alfonsina D’Amato et al.   Microbiome

Fecal microbiota transplantation from mice exposed to chronic intermittent hypoxia elicits sleep disturbances in naïve mice

(2020) Mohammad Badran et al.   EXPERIMENTAL NEUROLOGY

Age-Related Changes of the Neurovascular Unit in the Cerebral Cortex of Alzheimer Disease Mouse Models: A Neuroanatomical and Molecular Study

(2019) Alessandro Giuliani et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Priming of microglia with IFN-γ slows neuronal gamma oscillations in situ

(2019) Thuy-Truc Ta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Abnormal gut microbiota composition contributes to cognitive dysfunction in streptozotocin-induced diabetic mice

(2019) Fan Yu et al.   Aging-US

Thinking bigger: How early‐life environmental exposures shape the gut microbiome and influence the development of asthma and allergic disease

(2019) Hind Sbihi et al.   ALLERGY

Altered gut microbiota and inflammatory cytokine responses in patients with Parkinson’s disease

(2019) Chin-Hsien Lin et al.   Journal of Neuroinflammation

Single-cell analysis reveals T cell infiltration in old neurogenic niches

(2019) Ben W. Dulken et al.   NATURE

Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2

(2019) Evan Bolyen et al.   NATURE BIOTECHNOLOGY

Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

(2019) Daehwan Kim et al.   NATURE BIOTECHNOLOGY

Modified Mediterranean-ketogenic diet modulates gut microbiome and short-chain fatty acids in association with Alzheimer's disease markers in subjects with mild cognitive impairment

(2019) Ravinder Nagpal et al.   EBioMedicine

The Role of Gut Microbiota in Intestinal Inflammation with Respect to Diet and Extrinsic Stressors

(2019) Stefani Lobionda et al.   Microorganisms

Lessons learned from recent clinical trials of ketogenic diet therapies in adults

(2019) Tanya J.W. McDonald et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

The microbiota regulate neuronal function and fear extinction learning

(2019) Coco Chu et al.   NATURE

Berberine improved experimental chronic colitis by regulating interferon-γ- and IL-17A-producing lamina propria CD4+ T cells through AMPK activation

(2019) Masahiro Takahara et al.   Scientific Reports

AMPK activation increases postoperative cognitive impairment in intermittent hypoxia rats via direct activating PAK2

(2019) Xi Mei et al.   BEHAVIOURAL BRAIN RESEARCH

An integrated fecal microbiome and metabolome in the aged mice reveal anti-aging effects from the intestines and biochemical mechanism of FuFang zhenshu TiaoZhi(FTZ)

(2019) Piao Shenghua et al.   BIOMEDICINE & PHARMACOTHERAPY

The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet

(2018) Christine A. Olson et al.   CELL

Altered interferon-γ expression in lymphocytes as a potential peripheral marker of chronic stress-induced cognitive deficit

(2018) María Laura Palumbo et al.   CYTOKINE

High altitude with monotonous environment has significant impact on mood and cognitive performance of acclimatized lowlanders: Possible role of altered serum BDNF and plasma homocysteine level

(2018) Saroj Kumar Das et al.   JOURNAL OF AFFECTIVE DISORDERS

Hypoxia-Induced Signaling Activation in Neurodegenerative Diseases: Targets for New Therapeutic Strategies

(2018) Niraj Kumar Jha et al.   JOURNAL OF ALZHEIMERS DISEASE

Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

(2018) Melanie D. Sweeney et al.   Nature Reviews Neurology

High-fat diet aggravates postoperative cognitive dysfunction in aged mice

(2018) Lan Wei et al.   BMC Anesthesiology

Intermittent Hypoxia and Hypercapnia, a Hallmark of Obstructive Sleep Apnea, Alters the Gut Microbiome and Metabolome

(2018) Anupriya Tripathi et al.   mSystems

Cognitive benefits of the ketogenic diet in patients with epilepsy: A systematic overview

(2018) Annemiek A. van Berkel et al.   EPILEPSY & BEHAVIOR

Short-chain fatty acids: microbial metabolites that alleviate stress-induced brain-gut axis alterations

(2018) Marcel van de Wouw et al.   JOURNAL OF PHYSIOLOGY-LONDON

Low-fat versus ketogenic diet in Parkinson's disease: A pilot randomized controlled trial

(2018) Matthew C.L. Phillips et al.   MOVEMENT DISORDERS

IFN-γ, IL-17A, or zonulin rapidly increase the permeability of the blood-brain and small intestinal epithelial barriers: Relevance for neuro-inflammatory diseases

(2018) Mohammed T. Rahman et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effects of a medium-chain triglyceride-based ketogenic formula on cognitive function in patients with mild-to-moderate Alzheimer’s disease

(2018) Miho Ota et al.   NEUROSCIENCE LETTERS

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Insight into potential mechanisms of hypobaric hypoxia–induced learning and memory deficit – Lessons from rat studies

(2017) EYA Qaid et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Differential Regulation of NMDA Receptor-Mediated Transmission by SK Channels Underlies Dorsal-Ventral Differences in Dynamics of Schaffer Collateral Synaptic Function

(2017) Walter E. Babiec et al.   JOURNAL OF NEUROSCIENCE

Impact of High-Fat Diet and Early Stress on Depressive-Like Behavior and Hippocampal Plasticity in Adult Male Rats

(2017) Danusa Mar Arcego et al.   MOLECULAR NEUROBIOLOGY

Ketogenic diets improve behaviors associated with autism spectrum disorder in a sex-specific manner in the EL mouse

(2017) David N. Ruskin et al.   PHYSIOLOGY & BEHAVIOR

Deblur Rapidly Resolves Single-Nucleotide Community Sequence Patterns

(2017) Amnon Amir et al.   mSystems

The Effects of a High-Energy Diet on Hippocampal Function and Blood-Brain Barrier Integrity in the Rat

(2017) Scott E. Kanoski et al.   JOURNAL OF ALZHEIMERS DISEASE

Gut microbiome alterations in Alzheimer’s disease

(2017) Nicholas M. Vogt et al.   Scientific Reports

Cognitive impairment by antibiotic-induced gut dysbiosis: Analysis of gut microbiota-brain communication

(2016) Esther E. Fröhlich et al.   BRAIN BEHAVIOR AND IMMUNITY

Microbial Reconstitution Reverses Maternal Diet-Induced Social and Synaptic Deficits in Offspring

(2016) Shelly A. Buffington et al.   CELL

Translational Challenge Models in Support of Efficacy Studies: Effect of Cerebral Hypoxia on Cognitive Performances in Rodents

(2016) Julie Deguil et al.   CNS & Neurological Disorders-Drug Targets

Synergistic stress exacerbation in hippocampal neurons: Evidence favoring the dual-hit hypothesis of neurodegeneration

(2016) Scott D. Heinemann et al.   HIPPOCAMPUS

A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain

(2016) Knut H. Lauritzen et al.   NEUROBIOLOGY OF AGING

Global hypoxia induced impairment in learning and spatial memory is associated with precocious hippocampal aging

(2016) Suryanarayan Biswal et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Behavioural and neurochemical consequences of chronic gut microbiota depletion during adulthood in the rat

(2016) A.E. Hoban et al.   NEUROSCIENCE

Ly6Chi Monocytes Provide a Link between Antibiotic-Induced Changes in Gut Microbiota and Adult Hippocampal Neurogenesis

(2016) Luisa Möhle et al.   Cell Reports

Absence of IFNγ promotes hippocampal plasticity and enhances cognitive performance

(2016) S Monteiro et al.   Translational Psychiatry

Influence of gonadal hormones on the behavioral effects of intermittent hypoxia in mice

(2015) Taryn G. Aubrecht et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Bifidobacteria modulate cognitive processes in an anxious mouse strain

(2015) H.M. Savignac et al.   BEHAVIOURAL BRAIN RESEARCH

Adult Hippocampal Neurogenesis Is Regulated by the Microbiome

(2015) Ebere S. Ogbonnaya et al.   BIOLOGICAL PSYCHIATRY

Control of Brain Development, Function, and Behavior by the Microbiome

(2015) Timothy R. Sampson et al.   Cell Host & Microbe

Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling

(2015) Robert Caesar et al.   Cell Metabolism

Role of the Gut Microbiome in Obstructive Sleep Apnea–Induced Hypertension

(2015) David J. Durgan et al.   HYPERTENSION

TGFβ1 inhibits IFNγ-mediated microglia activation and protects mDA neurons from IFNγ-driven neurotoxicity

(2015) Xiaolai Zhou et al.   JOURNAL OF NEUROCHEMISTRY

Effects of high-fat diet exposure on learning & memory

(2015) Zachary A. Cordner et al.   PHYSIOLOGY & BEHAVIOR

Spatial Cognition in Adult and Aged Mice Exposed to High-Fat Diet

(2015) James P. Kesby et al.   PLoS One

Gut microbiota and aging

(2015) P. W. OToole et al.   SCIENCE

Diet-Induced Cognitive Deficits: The Role of Fat and Sugar, Potential Mechanisms and Nutritional Interventions

(2015) Jessica Beilharz et al.   Nutrients

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

From Chronic Cerebral Hypoperfusion to Alzheimer-Like Brain Pathology and Neurodegeneration

(2014) Yang Zhao et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

IFN-γ differentially modulates memory-related processes under basal and chronic stressor conditions

(2014) Darcy Litteljohn et al.   Frontiers in Cellular Neuroscience

Prevalences of dementia and cognitive impairment among older people in sub-Saharan Africa: a systematic review

(2013) Angelique Mavrodaris et al.   BULLETIN OF THE WORLD HEALTH ORGANIZATION

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

(2013) Elaine Y. Hsiao et al.   CELL

Vascular Risk Factors and Neurodegeneration in Ageing Related Dementias: Alzheimer’s Disease and Vascular Dementia

(2013) Rufus Akinyemi et al.   Current Alzheimer Research

Interleukin-2 at the Crossroads of Effector Responses, Tolerance, and Immunotherapy

(2013) Wei Liao et al.   IMMUNITY

IFN-  Production by Amyloid  -Specific Th1 Cells Promotes Microglial Activation and Increases Plaque Burden in a Mouse Model of Alzheimer's Disease

(2013) T. C. Browne et al.   JOURNAL OF IMMUNOLOGY

Microbiota is essential for social development in the mouse

(2013) L Desbonnet et al.   MOLECULAR PSYCHIATRY

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

A Shortened Barnes Maze Protocol Reveals Memory Deficits at 4-Months of Age in the Triple-Transgenic Mouse Model of Alzheimer's Disease

(2013) Aida Attar et al.   PLoS One

Estriol preserves synaptic transmission in the hippocampus during autoimmune demyelinating disease

(2012) Marina O Ziehn et al.   LABORATORY INVESTIGATION

Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10 −/− mice

(2012) Suzanne Devkota et al.   NATURE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

High altitude exposure impairs sleep patterns, mood, and cognitive functions

(2012) Valdir Aquino Lemos et al.   PSYCHOPHYSIOLOGY

Immunohistological markers for proliferative events, gliogenesis, and neurogenesis within the adult hippocampus

(2011) Oliver von Bohlen und Halbach   CELL AND TISSUE RESEARCH

Protective effect of the ketogenic diet in Scn1a mutant mice

(2011) Stacey B. B. Dutton et al.   EPILEPSIA

T-bet deficient mice exhibit resistance to stress-induced development of depression-like behaviors

(2011) Soo-Jeong Kim et al.   JOURNAL OF NEUROIMMUNOLOGY

Depletion of Murine Intestinal Microbiota: Effects on Gut Mucosa and Epithelial Gene Expression

(2011) Dag Henrik Reikvam et al.   PLoS One

Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

(2011) J. A. Bravo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Programming infant gut microbiota: influence of dietary and environmental factors

(2010) Tatiana Milena Marques et al.   CURRENT OPINION IN BIOTECHNOLOGY

Bacterial infection causes stress-induced memory dysfunction in mice

(2010) M. G. Gareau et al.   GUT

Regulation of learning and memory by meningeal immunity: a key role for IL-4

(2010) Noël C. Derecki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Western diet consumption and cognitive impairment: Links to hippocampal dysfunction and obesity

(2010) Scott E. Kanoski et al.   PHYSIOLOGY & BEHAVIOR

Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample

(2010) J. G. Caporaso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cognitive impairment following high fat diet consumption is associated with brain inflammation

(2009) Paul J. Pistell et al.   JOURNAL OF NEUROIMMUNOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Anticonvulsant profile of a balanced ketogenic diet in acute mouse seizure models

(2008) Ramakrishna Samala et al.   EPILEPSY RESEARCH

Interferon-γ directly induces neurotoxicity through a neuron specific, calcium-permeable complex of IFN-γ receptor and AMPA GluR1 receptor

(2008) Tetsuya Mizuno et al.   FASEB JOURNAL

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH