Journal
HUMAN & EXPERIMENTAL TOXICOLOGY
Volume 36, Issue 12, Pages 1315-1325Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/0960327116689714
Keywords
High altitude; hypoxia; learning; memory; rats
Categories
Funding
- USM Short-term Grant [304/PPSP/61313086]
Ask authors/readers for more resources
Impairment of memory is one of the most frequently reported symptoms during sudden hypoxia exposure in human. Cortical atrophy has been linked to the impaired memory function and is suggested to occur with chronic high-altitude exposure. However, the precise molecular mechanism(s) of hypoxia-induced memory impairment remains an enigma. In this work, we review hypoxia-induced learning and memory deficit in human and rat studies. Based on data from rat studies using different protocols of continuous hypoxia, we try to elicit potential mechanisms of hypobaric hypoxia-induced memory deficit.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available