Metformin facilitates mesenchymal stem cell-derived extracellular nanovesicles release and optimizes therapeutic efficacy in intervertebral disc degeneration

Title
Metformin facilitates mesenchymal stem cell-derived extracellular nanovesicles release and optimizes therapeutic efficacy in intervertebral disc degeneration
Authors
Keywords
Intervertebral disc degeneration, Mesenchymal stem cells, Extracellular vesicles, Metformin, Autophagy
Journal
BIOMATERIALS
Volume 274, Issue -, Pages 120850
Publisher
Elsevier BV
Online
2021-05-06
DOI
10.1016/j.biomaterials.2021.120850

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