Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A

Gut Microbiota Promotes Tumor Growth in Mice by Modulating Immune Response

(2018) Vrishketan Sethi et al.   GASTROENTEROLOGY

Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling

(2018) Frederik Johannes Verweij et al.   JOURNAL OF CELL BIOLOGY

The microbiome in cancer immunotherapy: Diagnostic tools and therapeutic strategies

(2018) Laurence Zitvogel et al.   SCIENCE

High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer

(2018) Amrita Datta et al.   Scientific Reports

Structural ensemble-based docking simulation and biophysical studies discovered new inhibitors of Hsp90 N-terminal domain

(2018) Hyun-Hwi Kim et al.   Scientific Reports

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

(2018) Gang Chen et al.   NATURE

Disruption of Circulating Extracellular Vesicles as a Novel Therapeutic Strategy against Cancer Metastasis

(2017) Nao Nishida-Aoki et al.   MOLECULAR THERAPY

Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding

(2017) Manuel Alonso Y Adell et al.   eLife

Exosomal MicroRNAs in Breast Cancer towards Diagnostic and Therapeutic Applications

(2017) Lorenzo Sempere et al.   Cancers

Increased liver-specific proteins in circulating extracellular vesicles as potential biomarkers for drug- and alcohol-induced liver injury

(2017) Young-Eun Cho et al.   PLoS One

Endothelin therapeutics in cancer: Where are we?

(2016) Laura Rosanò et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Communication by Extracellular Vesicles: Where We Are and Where We Need to Go

(2016) Mercedes Tkach et al.   CELL

Quantitative determination of sulfisoxazole and its three N-acetylated metabolites using HPLC–MS/MS, and the saturable pharmacokinetics of sulfisoxazole in mice

(2016) Kyungsoo Oh et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Malignant messengers

(2016) J. Kaiser   SCIENCE

Exosomes: The Link between GPCR Activation and Metastatic Potential?

(2016) Allison L. Isola et al.   Frontiers in Genetics

Cells release subpopulations of exosomes with distinct molecular and biological properties

(2016) Eduard Willms et al.   Scientific Reports

Identification of Developmental Endothelial Locus-1 on Circulating Extracellular Vesicles as a Novel Biomarker for Early Breast Cancer Detection

(2015) P.-G. Moon et al.   CLINICAL CANCER RESEARCH

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

Glypican-1 identifies cancer exosomes and detects early pancreatic cancer

(2015) Sonia A. Melo et al.   NATURE

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

(2015) Bruno Costa-Silva et al.   NATURE CELL BIOLOGY

Cancer and the microbiota

(2015) W. S. Garrett   SCIENCE

Role of the normal gut microbiota

(2015) Sai Manasa Jandhyala   WORLD JOURNAL OF GASTROENTEROLOGY

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Controlled exosome release from the retinal pigment epithelium in situ

(2014) Christina J. Locke et al.   EXPERIMENTAL EYE RESEARCH

Exosomes and Autophagy: Coordinated Mechanisms for the Maintenance of Cellular Fitness

(2014) Francesc Baixauli et al.   Frontiers in Immunology

Cardiomyocyte-specific deletion of endothelin receptor A rescues aging-associated cardiac hypertrophy and contractile dysfunction: role of autophagy

(2013) Asli F. Ceylan-Isik et al.   BASIC RESEARCH IN CARDIOLOGY

Tumor metastasis: moving new biological insights into the clinic

(2013) Liling Wan et al.   NATURE MEDICINE

Extracellular vesicles: biology and emerging therapeutic opportunities

(2013) Samir EL Andaloussi et al.   NATURE REVIEWS DRUG DISCOVERY

Rab27a Supports Exosome-Dependent and -Independent Mechanisms That Modify the Tumor Microenvironment and Can Promote Tumor Progression

(2012) A. Bobrie et al.   CANCER RESEARCH

Microvesicle and tunneling nanotube mediated intercellular transfer of g-protein coupled receptors in cell cultures

(2012) M. Guescini et al.   EXPERIMENTAL CELL RESEARCH

Clinical trials with endothelin receptor antagonists: What went wrong and where can we improve?

(2012) Donald E. Kohan et al.   LIFE SCIENCES

Get on the exosome bus with ALIX

(2012) James H. Hurley et al.   NATURE CELL BIOLOGY

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

Tumor Metastasis: Molecular Insights and Evolving Paradigms

(2011) Scott Valastyan et al.   CELL

The ESCRT Pathway

(2011) William M. Henne et al.   DEVELOPMENTAL CELL

The Tetraspanin CD63 Regulates ESCRT-Independent and -Dependent Endosomal Sorting during Melanogenesis

(2011) Guillaume van Niel et al.   DEVELOPMENTAL CELL

In-depth Identification of Pathways Related to Cisplatin-induced Hepatotoxicity through an Integrative Method Based on an Informatics-assisted Label-free Protein Quantitation and Microarray Gene Expression Approach

(2011) Young-Eun Cho et al.   MOLECULAR & CELLULAR PROTEOMICS

Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy

(2011) Pyong-Gon Moon et al.   PROTEOMICS

Secretion of extracellular hsp90α via exosomes increases cancer cell motility: a role for plasminogen activation

(2010) Jessica McCready et al.   BMC CANCER

Acid sphingomyelinase activity triggers microparticle release from glial cells

(2009) Fabio Bianco et al.   EMBO JOURNAL

Systemic Spread Is an Early Step in Breast Cancer

(2008) Yves Hüsemann et al.   CANCER CELL

Microphthalmia-associated Transcription Factor RegulatesRAB27AGene Expression and Controls Melanosome Transport

(2008) Christine Chiaverini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL