NUAK2 and RCan2 participate in the p53 mutant pro-tumorigenic network

Mutant p53 as a Regulator and Target of Autophagy

(2021) Yong Shi et al.   Frontiers in Oncology

Mutant p53 Gain-of-Function: Role in Cancer Development, Progression, and Therapeutic Approaches

(2021) Eduardo Alvarado-Ortiz et al.   Frontiers in Cell and Developmental Biology

The biological underpinnings of therapeutic resistance in pancreatic cancer

(2021) Gregory L. Beatty et al.   GENES & DEVELOPMENT

Epigenetic “Drivers” of Cancer

(2021) Alessio Butera et al.   JOURNAL OF MOLECULAR BIOLOGY

The International Collaboration for Research methods Development in Oncology (CReDO) workshops: shaping the future of global oncology research

(2021) Priya Ranganathan et al.   LANCET ONCOLOGY

The pancreatic cancer genome revisited

(2021) Akimasa Hayashi et al.   Nature Reviews Gastroenterology & Hepatology

A Narrative Review of Implementing Precision Oncology in Metastatic Castration-Resistant Prostate Cancer in Emerging Countries

(2021) Shouki Bazarbashi et al.   Oncology and Therapy

Predictability of drug-induced liver injury by machine learning

(2020) Marco Chierici et al.   Biology Direct

Autophagy, replication stress and DNA synthesis, an intricate relationship

(2020) Francesco Cecconi   CELL DEATH AND DIFFERENTIATION

Autophagy participates in, well, just about everything

(2020) Daniel J. Klionsky   CELL DEATH AND DIFFERENTIATION

Saga of Mcl-1: regulation from transcription to degradation

(2020) Viacheslav V. Senichkin et al.   CELL DEATH AND DIFFERENTIATION

Deleting key autophagy elongation proteins induces acquirement of tumor-associated phenotypes via ISG15

(2020) EunBin Kong et al.   CELL DEATH AND DIFFERENTIATION

Pan-cancer analysis of whole genomes

(2020)   NATURE

Paradise revealed III: why so many ways to die? Apoptosis, necroptosis, pyroptosis, and beyond

(2020) Marcelo Pires Amaral et al.   CELL DEATH AND DIFFERENTIATION

Computational identification and characterization of glioma candidate biomarkers through multi-omics integrative profiling

(2020) Lin Liu et al.   Biology Direct

The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic

(2020) Eliran Kadosh et al.   NATURE

Outcome of Clinical Genetic Testing in Patients with Features Suggestive for Hereditary Predisposition to PTH-Mediated Hypercalcemia

(2020) Shafaq Khairi et al.   Hormones & Cancer

Cancer predictive studies

(2020) Ivano Amelio et al.   Biology Direct

p53 deficiency triggers dysregulation of diverse cellular processes in physiological oxygen

(2020) Liz J. Valente et al.   JOURNAL OF CELL BIOLOGY

A loss-of-function NUAK2 mutation in humans causes anencephaly due to impaired Hippo-YAP signaling

(2020) Carine Bonnard et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Attenuation of p53 mutant as an approach for treatment Her2-positive cancer

(2020) Olga Fedorova et al.   Cell Death Discovery

Systematic evaluation of supervised machine learning for sample origin prediction using metagenomic sequencing data

(2020) Julie Chih-yu Chen et al.   Biology Direct

Commensal microbes and p53 in cancer progression

(2020) Ivana Celardo et al.   Biology Direct

Nerve fibers in the tumor microenvironment in neurotropic cancer—pancreatic cancer and cholangiocarcinoma

(2020) Xiuxiang Tan et al.   ONCOGENE

Dissecting the DNA binding landscape and gene regulatory network of p63 and p53

(2020) Konstantin Riege et al.   eLife

Liquid biopsies and cancer omics

(2020) Ivano Amelio et al.   Cell Death Discovery

From tumors to species: a SCANDAL hypothesis

(2019) A. Y. Panchin et al.   Biology Direct

Robust pathway-based multi-omics data integration using directed random walks for survival prediction in multiple cancer studies

(2019) So Yeon Kim et al.   Biology Direct

Associating expression and genomic data using co-occurrence measures

(2019) Maarten Larmuseau et al.   Biology Direct

Two well-differentiated pancreatic neuroendocrine tumor mouse models

(2019) Chung Wong et al.   CELL DEATH AND DIFFERENTIATION

Siva plays a critical role in mouse embryonic development

(2019) Suzanne B. R. Jacobs et al.   CELL DEATH AND DIFFERENTIATION

Integration of molecular features with clinical information for predicting outcomes for neuroblastoma patients

(2019) Yatong Han et al.   Biology Direct

Life or Death after a Break: What Determines the Choice?

(2019) Lenno Krenning et al.   MOLECULAR CELL

A novel framework for horizontal and vertical data integration in cancer studies with application to survival time prediction models

(2019) Iliyan Mihaylov et al.   Biology Direct

Do Mutations Turn p53 into an Oncogene?

(2019) Consuelo Pitolli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Computational Statistics Approach to Evaluate Blood Biomarkers for Breast Cancer Risk Stratification

(2019) Kaan Oktay et al.   Hormones & Cancer

Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors

(2018) Jaclyn Andricovich et al.   CANCER CELL

Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics

(2018) Li Ding et al.   CELL

TP53 gain-of-function mutation promotes inflammation in glioblastoma

(2018) Seok Won Ham et al.   CELL DEATH AND DIFFERENTIATION

Deciphering p53 signaling in tumor suppression

(2018) Stephano S Mello et al.   CURRENT OPINION IN CELL BIOLOGY

p73 Alternative Splicing: Exploring a Biological Role for the C-Terminal Isoforms

(2018) Polina Vikhreva et al.   JOURNAL OF MOLECULAR BIOLOGY

Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion

(2018) Ramona Schulz-Heddergott et al.   CANCER CELL

A feed forward loop enforces YAP/TAZ signaling during tumorigenesis

(2018) Mandeep K. Gill et al.   Nature Communications

Familial Cancer Clustering in Patients with Prolactinoma

(2018) Sandra Pekic et al.   Hormones & Cancer

Mutant p53-dependent mitochondrial metabolic alterations in a mesenchymal stem cell-based model of progressive malignancy

(2018) Giuseppe Lonetto et al.   CELL DEATH AND DIFFERENTIATION

Hypoxia-induced autophagy of stellate cells inhibits expression and secretion of lumican into microenvironment of pancreatic ductal adenocarcinoma

(2018) Xinqun Li et al.   CELL DEATH AND DIFFERENTIATION

Mutant p53 as a guardian of the cancer cell

(2018) Fiamma Mantovani et al.   CELL DEATH AND DIFFERENTIATION

p53 mutants cooperate with HIF-1 in transcriptional regulation of extracellular matrix components to promote tumor progression

(2018) Ivano Amelio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NUAK2 is a critical YAP target in liver cancer

(2018) Wei-Chien Yuan et al.   Nature Communications

Aggressiveness of Localized Prostate Cancer: the Key Value of Testosterone Deficiency Evaluated by Both Total and Bioavailable Testosterone: AndroCan Study Results

(2018) Yann Neuzillet et al.   Hormones & Cancer

Downregulation of IGF1R Expression Inhibits Growth and Enhances Cisplatin Sensitivity of Head and Neck Squamous Cell Carcinoma Cells In Vitro

(2018) Ashraf Khalil et al.   Hormones & Cancer

A Targeted Bivalent Androgen Receptor Binding Compound for Prostate Cancer Therapy

(2018) Shafinaz Chowdhury et al.   Hormones & Cancer

Design of a Novel Composite H2S-Releasing Hydrogel for Cardiac Tissue Repair

(2016) Arianna Mauretti et al.   MACROMOLECULAR BIOSCIENCE

Genomic analyses identify molecular subtypes of pancreatic cancer

(2016) Peter Bailey et al.   NATURE

KRAS mutation leads to decreased expression of regulator of calcineurin 2, resulting in tumor proliferation in colorectal cancer

(2016) H Niitsu et al.   Oncogenesis

Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment

(2015) E. M. Alexandrova et al.   NATURE

The p53 family and the hypoxia-inducible factors (HIFs): determinants of cancer progression

(2015) Ivano Amelio et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling

(2014) Susann Weissmueller et al.   CELL

Evolution and dynamics of pancreatic cancer progression

(2013) S Yachida et al.   ONCOGENE

Recognition mechanism of p63 by the E3 ligase Itch

(2012) Alessia Bellomaria et al.   CELL CYCLE

Oxidative species and S-glutathionyl conjugates in the apoptosis induction by allyl thiosulfate

(2011) Ridvan Nepravishta et al.   FEBS Journal

Skn-1a/Oct-11 and ΔNp63α exert antagonizing effects on human keratin expression

(2010) Anna Maria Lena et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Recognition of p63 by the E3 ligase ITCH: Effect of an ectodermal dysplasia mutant

(2010) Alessia Bellomaria et al.   CELL CYCLE

Mutant p53 Drives Invasion by Promoting Integrin Recycling

(2009) Patricia A.J. Muller et al.   CELL

A Mutant-p53/Smad Complex Opposes p63 to Empower TGFβ-Induced Metastasis

(2009) Maddalena Adorno et al.   CELL

Nucleic Acid Binding of the RTN1-C C-Terminal Region: Toward the Functional Role of a Reticulon Protein†

(2008) Sonia Melino et al.   BIOCHEMISTRY